BE896972A - Derives de l'oxazolidinone-2 n-arylee optiquement actifs, inhibiteurs specifiques t reversibles de la nonoamine oxydase de type b et leur procede de preparation - Google Patents

Derives de l'oxazolidinone-2 n-arylee optiquement actifs, inhibiteurs specifiques t reversibles de la nonoamine oxydase de type b et leur procede de preparation

Info

Publication number
BE896972A
BE896972A BE0/210943A BE210943A BE896972A BE 896972 A BE896972 A BE 896972A BE 0/210943 A BE0/210943 A BE 0/210943A BE 210943 A BE210943 A BE 210943A BE 896972 A BE896972 A BE 896972A
Authority
BE
Belgium
Prior art keywords
preparation
type
optically active
amine oxidase
reversible inhibitors
Prior art date
Application number
BE0/210943A
Other languages
English (en)
Original Assignee
Delalande Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Delalande Sa filed Critical Delalande Sa
Publication of BE896972A publication Critical patent/BE896972A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • C07D263/24—Oxygen atoms attached in position 2 with hydrocarbon radicals, substituted by oxygen atoms, attached to other ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/28—Radicals substituted by nitrogen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
BE0/210943A 1982-06-08 1983-06-06 Derives de l'oxazolidinone-2 n-arylee optiquement actifs, inhibiteurs specifiques t reversibles de la nonoamine oxydase de type b et leur procede de preparation BE896972A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8209972A FR2528046B1 (fr) 1982-06-08 1982-06-08 Derives de l'oxazolidinone-2 n-arylee optiquement actifs, inhibiteurs specifiques et reversibles de la monoamine oxydase de type b et leur procede de preparation

Publications (1)

Publication Number Publication Date
BE896972A true BE896972A (fr) 1983-12-06

Family

ID=9274766

Family Applications (1)

Application Number Title Priority Date Filing Date
BE0/210943A BE896972A (fr) 1982-06-08 1983-06-06 Derives de l'oxazolidinone-2 n-arylee optiquement actifs, inhibiteurs specifiques t reversibles de la nonoamine oxydase de type b et leur procede de preparation

Country Status (13)

Country Link
US (1) US4598084A (fr)
JP (1) JPS5980668A (fr)
AU (1) AU1546283A (fr)
BE (1) BE896972A (fr)
CH (3) CH661500A5 (fr)
DE (1) DE3320394A1 (fr)
FR (1) FR2528046B1 (fr)
GB (3) GB2121413B (fr)
IT (1) IT1164269B (fr)
LU (1) LU84851A1 (fr)
NL (1) NL8302013A (fr)
SE (2) SE8303136L (fr)
ZA (1) ZA834119B (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60241893A (ja) * 1984-05-15 1985-11-30 Kanegafuchi Chem Ind Co Ltd 光学活性（ｓ）―オキサゾリジノン誘導体の製造方法
DE3525648A1 (de) * 1985-07-18 1987-01-29 Bokel Heinz Hermann Dr 1-oxa-2-oxo-2-r-3-aza-5-z-cyclopentanderivate
FR2609029B1 (fr) * 1986-12-30 1989-12-08 Delalande Sa Derives 5-aminoethyles de l'oxazolidinone-2, leur procede de preparation et leur application en therapeutique
FR2603279B1 (fr) * 1986-09-03 1988-12-16 Rech Ind Benzyloxy-phenyl-oxazolidinones, procede de preparation et utilisation en therapeutique
CA1302422C (fr) * 1986-09-03 1992-06-02 Margherita Strolin-Benedetti Derives 5-aminoethyloxazolidin-2-one, procede pour leur preparation et leurutilisation therapeutique
FR2626877B1 (fr) * 1988-02-05 1991-04-05 Delalande Sa Ethers alkyliques ou benzyliques du phenol, leurs procedes de preparation et leur application en therapeutique
US5196543A (en) * 1989-10-17 1993-03-23 Delalande S.A. 3-aryloxazolidinone derivatives, process for their preparation and their use in therapy
US5235063A (en) * 1989-10-17 1993-08-10 Delalande S.A. Process of preparing by condensation certain
CA2112487C (fr) * 1991-06-26 2003-04-15 James W. Young Methode et compositions pour le traitement des vomissements, des nausees et d'autres troubles a l'ondansetron optiquement pur r(+)
CA2124445A1 (fr) * 1991-11-26 1993-06-10 James W. Young Methodes et compositions pour le traitement de l'hypertension, de l'angor et d'autres troubles par la (-) amlodipine optiquement pure
WO2000051582A2 (fr) 1999-03-01 2000-09-08 Sepracor Inc. Procedes de traitement de l'apnee et de troubles de l'apnee a l'aide de r(+) ondansetron optiquement pur

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2356422A1 (fr) * 1976-03-01 1978-01-27 Delalande Sa Nouveaux hydroxymethyl-5 oxazolidinone-2, leur procede de preparation et leur application en therapeutique
FR2380780A2 (fr) * 1977-02-22 1978-09-15 Delalande Sa Application en therapeutique des hydroxymethyl-5 oxazolidinones-2, notamment comme antidepresseurs
LU80081A1 (fr) * 1977-08-26 1979-05-15 Delalande Sa Nouvelles hydroxymethyl-5 oxazolidinones-2,leur procede de preparation et leur application therapeutique
FR2428032A1 (fr) * 1978-06-09 1980-01-04 Delalande Sa Nouvelles oxazolidimones, oxazolidinethiones et pyrrolidinones, leur procede de preparation et leur application en therapeutique
US4348393A (en) * 1978-06-09 1982-09-07 Delalande S.A. N-Aryl oxazolidinones, oxazolidinethiones, pyrrolidinones, pyrrolidines and thiazolidinones

Also Published As

Publication number Publication date
SE8303136L (sv) 1983-12-09
GB2121413B (en) 1986-05-08
GB8512019D0 (en) 1985-06-19
GB2157693B (en) 1986-05-08
SE8303136D0 (sv) 1983-06-03
LU84851A1 (fr) 1985-03-29
GB2157692B (en) 1986-05-08
FR2528046A1 (fr) 1983-12-09
GB8315433D0 (en) 1983-07-13
GB2157693A (en) 1985-10-30
CH661507A5 (fr) 1987-07-31
GB2157692A (en) 1985-10-30
IT8321497A0 (it) 1983-06-07
SE8802281D0 (sv) 1988-06-17
DE3320394A1 (de) 1983-12-08
CH657362A5 (fr) 1986-08-29
NL8302013A (nl) 1984-01-02
SE8802281L (sv) 1988-06-17
GB8512020D0 (en) 1985-06-19
FR2528046B1 (fr) 1985-06-21
ZA834119B (en) 1984-03-28
US4598084A (en) 1986-07-01
AU1546283A (en) 1983-12-15
JPS5980668A (ja) 1984-05-10
IT1164269B (it) 1987-04-08
GB2121413A (en) 1983-12-21
CH661500A5 (fr) 1987-07-31

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: DELALANDE S.A.

Effective date: 19910630