ZA834119B - Optically active derivatives of n-arylated oxazolidine-2-one,the process for preparing same and their application in therapeutics - Google Patents

Optically active derivatives of n-arylated oxazolidine-2-one,the process for preparing same and their application in therapeutics

Info

Publication number
ZA834119B
ZA834119B ZA834119A ZA834119A ZA834119B ZA 834119 B ZA834119 B ZA 834119B ZA 834119 A ZA834119 A ZA 834119A ZA 834119 A ZA834119 A ZA 834119A ZA 834119 B ZA834119 B ZA 834119B
Authority
ZA
South Africa
Prior art keywords
arylated
oxazolidine
therapeutics
application
optically active
Prior art date
Application number
ZA834119A
Other languages
English (en)
Inventor
Margherita Strolin-Benedetti
Patrick Guerret
Michel Langlois
Philippe Dostert
Original Assignee
Delalande Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Delalande Sa filed Critical Delalande Sa
Publication of ZA834119B publication Critical patent/ZA834119B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • C07D263/24—Oxygen atoms attached in position 2 with hydrocarbon radicals, substituted by oxygen atoms, attached to other ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/28—Radicals substituted by nitrogen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Enzymes And Modification Thereof (AREA)
ZA834119A 1982-06-08 1983-06-07 Optically active derivatives of n-arylated oxazolidine-2-one,the process for preparing same and their application in therapeutics ZA834119B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8209972A FR2528046B1 (fr) 1982-06-08 1982-06-08 Derives de l'oxazolidinone-2 n-arylee optiquement actifs, inhibiteurs specifiques et reversibles de la monoamine oxydase de type b et leur procede de preparation

Publications (1)

Publication Number Publication Date
ZA834119B true ZA834119B (en) 1984-03-28

Family

ID=9274766

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA834119A ZA834119B (en) 1982-06-08 1983-06-07 Optically active derivatives of n-arylated oxazolidine-2-one,the process for preparing same and their application in therapeutics

Country Status (13)

Country Link
US (1) US4598084A (fr)
JP (1) JPS5980668A (fr)
AU (1) AU1546283A (fr)
BE (1) BE896972A (fr)
CH (3) CH661500A5 (fr)
DE (1) DE3320394A1 (fr)
FR (1) FR2528046B1 (fr)
GB (3) GB2121413B (fr)
IT (1) IT1164269B (fr)
LU (1) LU84851A1 (fr)
NL (1) NL8302013A (fr)
SE (2) SE8303136L (fr)
ZA (1) ZA834119B (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60241893A (ja) * 1984-05-15 1985-11-30 Kanegafuchi Chem Ind Co Ltd 光学活性（ｓ）―オキサゾリジノン誘導体の製造方法
DE3525648A1 (de) * 1985-07-18 1987-01-29 Bokel Heinz Hermann Dr 1-oxa-2-oxo-2-r-3-aza-5-z-cyclopentanderivate
FR2609029B1 (fr) * 1986-12-30 1989-12-08 Delalande Sa Derives 5-aminoethyles de l'oxazolidinone-2, leur procede de preparation et leur application en therapeutique
US4897409A (en) * 1986-09-03 1990-01-30 Delalande S.A. 5-aminoethyloxazolidin-2-one derivatives
FR2603279B1 (fr) * 1986-09-03 1988-12-16 Rech Ind Benzyloxy-phenyl-oxazolidinones, procede de preparation et utilisation en therapeutique
FR2626877B1 (fr) * 1988-02-05 1991-04-05 Delalande Sa Ethers alkyliques ou benzyliques du phenol, leurs procedes de preparation et leur application en therapeutique
US5196543A (en) * 1989-10-17 1993-03-23 Delalande S.A. 3-aryloxazolidinone derivatives, process for their preparation and their use in therapy
US5235063A (en) * 1989-10-17 1993-08-10 Delalande S.A. Process of preparing by condensation certain
CA2112487C (fr) * 1991-06-26 2003-04-15 James W. Young Methode et compositions pour le traitement des vomissements, des nausees et d'autres troubles a l'ondansetron optiquement pur r(+)
JPH07501547A (ja) * 1991-11-26 1995-02-16 セプラコア，インコーポレーテッド 光学的に純粋な（−）アムロジピンを用いる，高血圧，狭心症および他の疾患を治療するための方法および組成物
US6548082B1 (en) * 1999-03-01 2003-04-15 Sepracor Inc. Methods for treating apnea and apnea disorders using optically pure R(+) ondansetron

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2356422A1 (fr) * 1976-03-01 1978-01-27 Delalande Sa Nouveaux hydroxymethyl-5 oxazolidinone-2, leur procede de preparation et leur application en therapeutique
FR2380780A2 (fr) * 1977-02-22 1978-09-15 Delalande Sa Application en therapeutique des hydroxymethyl-5 oxazolidinones-2, notamment comme antidepresseurs
LU80081A1 (fr) * 1977-08-26 1979-05-15 Delalande Sa Nouvelles hydroxymethyl-5 oxazolidinones-2,leur procede de preparation et leur application therapeutique
FR2428032A1 (fr) * 1978-06-09 1980-01-04 Delalande Sa Nouvelles oxazolidimones, oxazolidinethiones et pyrrolidinones, leur procede de preparation et leur application en therapeutique
US4348393A (en) * 1978-06-09 1982-09-07 Delalande S.A. N-Aryl oxazolidinones, oxazolidinethiones, pyrrolidinones, pyrrolidines and thiazolidinones

Also Published As

Publication number Publication date
GB2121413A (en) 1983-12-21
US4598084A (en) 1986-07-01
JPS5980668A (ja) 1984-05-10
GB2157693A (en) 1985-10-30
FR2528046A1 (fr) 1983-12-09
SE8303136D0 (sv) 1983-06-03
GB8315433D0 (en) 1983-07-13
CH661500A5 (fr) 1987-07-31
IT1164269B (it) 1987-04-08
DE3320394A1 (de) 1983-12-08
GB2157692A (en) 1985-10-30
SE8303136L (sv) 1983-12-09
CH657362A5 (fr) 1986-08-29
AU1546283A (en) 1983-12-15
GB8512020D0 (en) 1985-06-19
SE8802281L (sv) 1988-06-17
NL8302013A (nl) 1984-01-02
BE896972A (fr) 1983-12-06
CH661507A5 (fr) 1987-07-31
SE8802281D0 (sv) 1988-06-17
FR2528046B1 (fr) 1985-06-21
GB2157693B (en) 1986-05-08
GB2121413B (en) 1986-05-08
IT8321497A0 (it) 1983-06-07
GB2157692B (en) 1986-05-08
LU84851A1 (fr) 1985-03-29
GB8512019D0 (en) 1985-06-19

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