LU84282A1 - Procede,composition et produit virulicides - Google Patents
Procede,composition et produit virulicides Download PDFInfo
- Publication number
- LU84282A1 LU84282A1 LU84282A LU84282A LU84282A1 LU 84282 A1 LU84282 A1 LU 84282A1 LU 84282 A LU84282 A LU 84282A LU 84282 A LU84282 A LU 84282A LU 84282 A1 LU84282 A1 LU 84282A1
- Authority
- LU
- Luxembourg
- Prior art keywords
- acid
- group
- lower alkyl
- alkyl group
- mixture
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title claims description 68
- 230000003253 viricidal effect Effects 0.000 title claims description 46
- 238000000034 method Methods 0.000 title claims description 26
- 230000008569 process Effects 0.000 title claims description 14
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 78
- 239000002253 acid Substances 0.000 claims description 68
- 241000700605 Viruses Species 0.000 claims description 62
- 125000000217 alkyl group Chemical group 0.000 claims description 38
- KDYFGRWQOYBRFD-UHFFFAOYSA-N Succinic acid Natural products OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 claims description 32
- 150000007513 acids Chemical class 0.000 claims description 29
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 claims description 26
- 239000000758 substrate Substances 0.000 claims description 23
- 239000004094 surface-active agent Substances 0.000 claims description 19
- BJEPYKJPYRNKOW-REOHCLBHSA-N (S)-malic acid Chemical compound OC(=O)[C@@H](O)CC(O)=O BJEPYKJPYRNKOW-REOHCLBHSA-N 0.000 claims description 18
- BJEPYKJPYRNKOW-UHFFFAOYSA-N alpha-hydroxysuccinic acid Natural products OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 claims description 18
- 239000001630 malic acid Substances 0.000 claims description 18
- 235000011090 malic acid Nutrition 0.000 claims description 18
- -1 alkyl phenols Chemical class 0.000 claims description 15
- 230000001815 facial effect Effects 0.000 claims description 14
- 239000005711 Benzoic acid Substances 0.000 claims description 13
- 235000010233 benzoic acid Nutrition 0.000 claims description 13
- 235000015165 citric acid Nutrition 0.000 claims description 13
- 239000001384 succinic acid Substances 0.000 claims description 13
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 claims description 11
- 125000003342 alkenyl group Chemical group 0.000 claims description 11
- 239000004744 fabric Substances 0.000 claims description 9
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 claims description 8
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims description 8
- 210000002345 respiratory system Anatomy 0.000 claims description 8
- 239000000463 material Substances 0.000 claims description 7
- 239000003945 anionic surfactant Substances 0.000 claims description 6
- KDYFGRWQOYBRFD-NUQCWPJISA-N butanedioic acid Chemical compound O[14C](=O)CC[14C](O)=O KDYFGRWQOYBRFD-NUQCWPJISA-N 0.000 claims description 6
- 150000002148 esters Chemical class 0.000 claims description 6
- 241001465754 Metazoa Species 0.000 claims description 5
- 159000000000 sodium salts Chemical class 0.000 claims description 5
- 125000001931 aliphatic group Chemical group 0.000 claims description 4
- 125000002091 cationic group Chemical group 0.000 claims description 4
- 150000001768 cations Chemical class 0.000 claims description 4
- 239000002085 irritant Substances 0.000 claims description 4
- 231100000021 irritant Toxicity 0.000 claims description 4
- 229910052751 metal Inorganic materials 0.000 claims description 4
- 239000002184 metal Substances 0.000 claims description 4
- 231100000252 nontoxic Toxicity 0.000 claims description 4
- 230000003000 nontoxic effect Effects 0.000 claims description 4
- 239000004753 textile Substances 0.000 claims description 3
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 claims description 2
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 claims 6
- ULUAUXLGCMPNKK-UHFFFAOYSA-N Sulfobutanedioic acid Chemical compound OC(=O)CC(C(O)=O)S(O)(=O)=O ULUAUXLGCMPNKK-UHFFFAOYSA-N 0.000 claims 4
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 claims 3
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 claims 3
- 239000003093 cationic surfactant Substances 0.000 claims 3
- 239000002736 nonionic surfactant Substances 0.000 claims 3
- 150000003839 salts Chemical class 0.000 claims 3
- 150000003242 quaternary ammonium salts Chemical class 0.000 claims 2
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims 1
- OFOBLEOULBTSOW-UHFFFAOYSA-N Propanedioic acid Natural products OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 claims 1
- VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid Chemical compound OC(=O)\C=C/C(O)=O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 claims 1
- 239000011976 maleic acid Substances 0.000 claims 1
- 239000004745 nonwoven fabric Substances 0.000 claims 1
- 125000001453 quaternary ammonium group Chemical class 0.000 claims 1
- 239000000600 sorbitol Substances 0.000 claims 1
- 210000001519 tissue Anatomy 0.000 description 35
- 241000709661 Enterovirus Species 0.000 description 24
- 238000010790 dilution Methods 0.000 description 19
- 239000012895 dilution Substances 0.000 description 19
- 238000012360 testing method Methods 0.000 description 15
- 208000015181 infectious disease Diseases 0.000 description 11
- 239000000243 solution Substances 0.000 description 11
- 239000003795 chemical substances by application Substances 0.000 description 10
- 241000701161 unidentified adenovirus Species 0.000 description 10
- 241000712461 unidentified influenza virus Species 0.000 description 10
- 238000002474 experimental method Methods 0.000 description 8
- 238000003556 assay Methods 0.000 description 7
- 230000002779 inactivation Effects 0.000 description 6
- 229910052740 iodine Inorganic materials 0.000 description 6
- 150000007524 organic acids Chemical class 0.000 description 6
- 235000005985 organic acids Nutrition 0.000 description 6
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 description 5
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 5
- 230000000844 anti-bacterial effect Effects 0.000 description 5
- 230000002458 infectious effect Effects 0.000 description 5
- 239000011630 iodine Substances 0.000 description 5
- 230000003612 virological effect Effects 0.000 description 5
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 4
- 241001135569 Human adenovirus 5 Species 0.000 description 4
- 239000007864 aqueous solution Substances 0.000 description 4
- 150000001735 carboxylic acids Chemical class 0.000 description 4
- 201000010099 disease Diseases 0.000 description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 4
- 210000003296 saliva Anatomy 0.000 description 4
- 241000894006 Bacteria Species 0.000 description 3
- 108020004414 DNA Proteins 0.000 description 3
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 3
- 230000009471 action Effects 0.000 description 3
- 230000005540 biological transmission Effects 0.000 description 3
- 239000006071 cream Substances 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 230000002070 germicidal effect Effects 0.000 description 3
- 239000006210 lotion Substances 0.000 description 3
- 238000012986 modification Methods 0.000 description 3
- 230000004048 modification Effects 0.000 description 3
- 230000003472 neutralizing effect Effects 0.000 description 3
- 238000002360 preparation method Methods 0.000 description 3
- 230000000241 respiratory effect Effects 0.000 description 3
- 208000023504 respiratory system disease Diseases 0.000 description 3
- 239000011780 sodium chloride Substances 0.000 description 3
- XZMCDFZZKTWFGF-UHFFFAOYSA-N Cyanamide Chemical compound NC#N XZMCDFZZKTWFGF-UHFFFAOYSA-N 0.000 description 2
- 102000053602 DNA Human genes 0.000 description 2
- VZCYOOQTPOCHFL-OWOJBTEDSA-N Fumaric acid Chemical compound OC(=O)\C=C\C(O)=O VZCYOOQTPOCHFL-OWOJBTEDSA-N 0.000 description 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 description 2
- LCTONWCANYUPML-UHFFFAOYSA-N Pyruvic acid Chemical compound CC(=O)C(O)=O LCTONWCANYUPML-UHFFFAOYSA-N 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 2
- 229940027983 antiseptic and disinfectant quaternary ammonium compound Drugs 0.000 description 2
- 239000012298 atmosphere Substances 0.000 description 2
- 239000003899 bactericide agent Substances 0.000 description 2
- 239000000969 carrier Substances 0.000 description 2
- NEHMKBQYUWJMIP-UHFFFAOYSA-N chloromethane Chemical compound ClC NEHMKBQYUWJMIP-UHFFFAOYSA-N 0.000 description 2
- 238000004140 cleaning Methods 0.000 description 2
- 239000011248 coating agent Substances 0.000 description 2
- 238000000576 coating method Methods 0.000 description 2
- 230000000120 cytopathologic effect Effects 0.000 description 2
- 238000001035 drying Methods 0.000 description 2
- 238000007654 immersion Methods 0.000 description 2
- 238000005470 impregnation Methods 0.000 description 2
- 238000011081 inoculation Methods 0.000 description 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 2
- 201000009240 nasopharyngitis Diseases 0.000 description 2
- 150000003856 quaternary ammonium compounds Chemical class 0.000 description 2
- YGSDEFSMJLZEOE-UHFFFAOYSA-N salicylic acid Chemical compound OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 description 2
- 238000009738 saturating Methods 0.000 description 2
- 210000002966 serum Anatomy 0.000 description 2
- 239000011734 sodium Substances 0.000 description 2
- APSBXTVYXVQYAB-UHFFFAOYSA-M sodium docusate Chemical compound [Na+].CCCCC(CC)COC(=O)CC(S([O-])(=O)=O)C(=O)OCC(CC)CCCC APSBXTVYXVQYAB-UHFFFAOYSA-M 0.000 description 2
- 239000007921 spray Substances 0.000 description 2
- 238000003892 spreading Methods 0.000 description 2
- 230000007480 spreading Effects 0.000 description 2
- 235000011044 succinic acid Nutrition 0.000 description 2
- 239000000725 suspension Substances 0.000 description 2
- 239000002966 varnish Substances 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 210000002268 wool Anatomy 0.000 description 2
- SUDDXMSROFLAQH-UHFFFAOYSA-N 2,3-dihydroxy-2-methylbutanedioic acid Chemical compound OC(=O)C(O)(C)C(O)C(O)=O SUDDXMSROFLAQH-UHFFFAOYSA-N 0.000 description 1
- YNOXCRMFGMSKIJ-UHFFFAOYSA-N 2-methylcitric acid Chemical compound OC(=O)C(C)C(O)(C(O)=O)CC(O)=O YNOXCRMFGMSKIJ-UHFFFAOYSA-N 0.000 description 1
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 description 1
- 208000010370 Adenoviridae Infections Diseases 0.000 description 1
- 108010077805 Bacterial Proteins Proteins 0.000 description 1
- 101100334117 Caenorhabditis elegans fah-1 gene Proteins 0.000 description 1
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 description 1
- 201000009030 Carcinoma Diseases 0.000 description 1
- 206010061041 Chlamydial infection Diseases 0.000 description 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 1
- 208000035473 Communicable disease Diseases 0.000 description 1
- 229930182566 Gentamicin Natural products 0.000 description 1
- CEAZRRDELHUEMR-URQXQFDESA-N Gentamicin Chemical compound O1[C@H](C(C)NC)CC[C@@H](N)[C@H]1O[C@H]1[C@H](O)[C@@H](O[C@@H]2[C@@H]([C@@H](NC)[C@@](C)(O)CO2)O)[C@H](N)C[C@@H]1N CEAZRRDELHUEMR-URQXQFDESA-N 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 239000012981 Hank's balanced salt solution Substances 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- ZDXPYRJPNDTMRX-VKHMYHEASA-N L-glutamine Chemical compound OC(=O)[C@@H](N)CCC(N)=O ZDXPYRJPNDTMRX-VKHMYHEASA-N 0.000 description 1
- 102000004895 Lipoproteins Human genes 0.000 description 1
- 108090001030 Lipoproteins Proteins 0.000 description 1
- 241000282560 Macaca mulatta Species 0.000 description 1
- CERQOIWHTDAKMF-UHFFFAOYSA-M Methacrylate Chemical compound CC(=C)C([O-])=O CERQOIWHTDAKMF-UHFFFAOYSA-M 0.000 description 1
- 101100412856 Mus musculus Rhod gene Proteins 0.000 description 1
- RSPISYXLHRIGJD-UHFFFAOYSA-N OOOO Chemical compound OOOO RSPISYXLHRIGJD-UHFFFAOYSA-N 0.000 description 1
- YAVWDJDEOLOYQO-UHFFFAOYSA-N OOOOOOOOOO Chemical compound OOOOOOOOOO YAVWDJDEOLOYQO-UHFFFAOYSA-N 0.000 description 1
- 208000002606 Paramyxoviridae Infections Diseases 0.000 description 1
- 201000007100 Pharyngitis Diseases 0.000 description 1
- BELBBZDIHDAJOR-UHFFFAOYSA-N Phenolsulfonephthalein Chemical compound C1=CC(O)=CC=C1C1(C=2C=CC(O)=CC=2)C2=CC=CC=C2S(=O)(=O)O1 BELBBZDIHDAJOR-UHFFFAOYSA-N 0.000 description 1
- 241000709664 Picornaviridae Species 0.000 description 1
- 241000711798 Rabies lyssavirus Species 0.000 description 1
- 208000018569 Respiratory Tract disease Diseases 0.000 description 1
- 206010039101 Rhinorrhoea Diseases 0.000 description 1
- 241000606651 Rickettsiales Species 0.000 description 1
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 description 1
- 208000036142 Viral infection Diseases 0.000 description 1
- 239000000443 aerosol Substances 0.000 description 1
- 238000013019 agitation Methods 0.000 description 1
- 230000007815 allergy Effects 0.000 description 1
- 229910000147 aluminium phosphate Inorganic materials 0.000 description 1
- 125000003277 amino group Chemical group 0.000 description 1
- 125000000129 anionic group Chemical group 0.000 description 1
- 230000000840 anti-viral effect Effects 0.000 description 1
- 239000000427 antigen Substances 0.000 description 1
- 230000000890 antigenic effect Effects 0.000 description 1
- 102000036639 antigens Human genes 0.000 description 1
- 108091007433 antigens Proteins 0.000 description 1
- 229960000686 benzalkonium chloride Drugs 0.000 description 1
- 229960003872 benzethonium Drugs 0.000 description 1
- CADWTSSKOVRVJC-UHFFFAOYSA-N benzyl(dimethyl)azanium;chloride Chemical compound [Cl-].C[NH+](C)CC1=CC=CC=C1 CADWTSSKOVRVJC-UHFFFAOYSA-N 0.000 description 1
- 239000013060 biological fluid Substances 0.000 description 1
- 229910052794 bromium Inorganic materials 0.000 description 1
- 206010006451 bronchitis Diseases 0.000 description 1
- 238000004364 calculation method Methods 0.000 description 1
- 244000309466 calf Species 0.000 description 1
- 210000000234 capsid Anatomy 0.000 description 1
- 125000004432 carbon atom Chemical group C* 0.000 description 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 description 1
- 125000005019 carboxyalkenyl group Chemical group 0.000 description 1
- 229910052801 chlorine Inorganic materials 0.000 description 1
- XFTRTWQBIOMVPK-UHFFFAOYSA-N citramalic acid Chemical compound OC(=O)C(O)(C)CC(O)=O XFTRTWQBIOMVPK-UHFFFAOYSA-N 0.000 description 1
- 239000011538 cleaning material Substances 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 125000004093 cyano group Chemical group *C#N 0.000 description 1
- 239000000645 desinfectant Substances 0.000 description 1
- 230000001627 detrimental effect Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 238000002405 diagnostic procedure Methods 0.000 description 1
- SIYLLGKDQZGJHK-UHFFFAOYSA-N dimethyl-(phenylmethyl)-[2-[2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]ethoxy]ethyl]ammonium Chemical compound C1=CC(C(C)(C)CC(C)(C)C)=CC=C1OCCOCC[N+](C)(C)CC1=CC=CC=C1 SIYLLGKDQZGJHK-UHFFFAOYSA-N 0.000 description 1
- 231100000676 disease causative agent Toxicity 0.000 description 1
- 229910000397 disodium phosphate Inorganic materials 0.000 description 1
- 238000004821 distillation Methods 0.000 description 1
- 210000000981 epithelium Anatomy 0.000 description 1
- 230000001605 fetal effect Effects 0.000 description 1
- 239000002657 fibrous material Substances 0.000 description 1
- 229910052731 fluorine Inorganic materials 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 238000007710 freezing Methods 0.000 description 1
- 230000008014 freezing Effects 0.000 description 1
- 239000001530 fumaric acid Substances 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- ZDXPYRJPNDTMRX-UHFFFAOYSA-N glutamine Natural products OC(=O)C(N)CCC(N)=O ZDXPYRJPNDTMRX-UHFFFAOYSA-N 0.000 description 1
- 238000007646 gravure printing Methods 0.000 description 1
- 125000005843 halogen group Chemical group 0.000 description 1
- 230000009931 harmful effect Effects 0.000 description 1
- 239000008240 homogeneous mixture Substances 0.000 description 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 description 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 1
- 125000004464 hydroxyphenyl group Chemical group 0.000 description 1
- 230000001524 infective effect Effects 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 230000007794 irritation Effects 0.000 description 1
- 239000004310 lactic acid Substances 0.000 description 1
- 235000014655 lactic acid Nutrition 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 229940050176 methyl chloride Drugs 0.000 description 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
- 230000002906 microbiologic effect Effects 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 238000002941 microtiter virus yield reduction assay Methods 0.000 description 1
- 239000002324 mouth wash Substances 0.000 description 1
- LNOPIUAQISRISI-UHFFFAOYSA-N n'-hydroxy-2-propan-2-ylsulfonylethanimidamide Chemical compound CC(C)S(=O)(=O)CC(N)=NO LNOPIUAQISRISI-UHFFFAOYSA-N 0.000 description 1
- 208000010753 nasal discharge Diseases 0.000 description 1
- 239000007922 nasal spray Substances 0.000 description 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 description 1
- 231100000344 non-irritating Toxicity 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 description 1
- 239000012188 paraffin wax Substances 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 229960003531 phenolsulfonphthalein Drugs 0.000 description 1
- 229920000136 polysorbate Polymers 0.000 description 1
- UAJUXJSXCLUTNU-UHFFFAOYSA-N pranlukast Chemical compound C=1C=C(OCCCCC=2C=CC=CC=2)C=CC=1C(=O)NC(C=1)=CC=C(C(C=2)=O)C=1OC=2C=1N=NNN=1 UAJUXJSXCLUTNU-UHFFFAOYSA-N 0.000 description 1
- 229960004583 pranlukast Drugs 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 229940107700 pyruvic acid Drugs 0.000 description 1
- 230000035484 reaction time Effects 0.000 description 1
- 210000005084 renal tissue Anatomy 0.000 description 1
- 229920002477 rna polymer Polymers 0.000 description 1
- 229960004889 salicylic acid Drugs 0.000 description 1
- 239000012266 salt solution Substances 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 238000005201 scrubbing Methods 0.000 description 1
- 238000013207 serial dilution Methods 0.000 description 1
- 239000002356 single layer Substances 0.000 description 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 125000000020 sulfo group Chemical group O=S(=O)([*])O[H] 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 230000009897 systematic effect Effects 0.000 description 1
- 235000002906 tartaric acid Nutrition 0.000 description 1
- 239000011975 tartaric acid Substances 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 238000010257 thawing Methods 0.000 description 1
- 125000003396 thiol group Chemical group [H]S* 0.000 description 1
- 238000004448 titration Methods 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- GPRLSGONYQIRFK-MNYXATJNSA-N triton Chemical compound [3H+] GPRLSGONYQIRFK-MNYXATJNSA-N 0.000 description 1
- 241001529453 unidentified herpesvirus Species 0.000 description 1
- 230000009385 viral infection Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US28468881A | 1981-07-20 | 1981-07-20 | |
| US28468881 | 1981-07-20 | ||
| US39278182A | 1982-06-30 | 1982-06-30 | |
| US39278182 | 1982-06-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| LU84282A1 true LU84282A1 (fr) | 1983-02-07 |
Family
ID=26962741
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| LU84282A LU84282A1 (fr) | 1981-07-20 | 1982-07-20 | Procede,composition et produit virulicides |
Country Status (14)
| Country | Link |
|---|---|
| KR (1) | KR870002047B1 (de) |
| AU (1) | AU554127B2 (de) |
| CA (1) | CA1188225A (de) |
| DE (1) | DE3227126C2 (de) |
| DK (1) | DK315482A (de) |
| FI (1) | FI822542L (de) |
| FR (1) | FR2509577B1 (de) |
| GB (1) | GB2103089B (de) |
| GR (1) | GR76879B (de) |
| IT (1) | IT1212049B (de) |
| LU (1) | LU84282A1 (de) |
| NL (1) | NL8202885A (de) |
| PH (1) | PH21282A (de) |
| SE (1) | SE8204372L (de) |
Families Citing this family (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3229097A1 (de) * | 1982-08-04 | 1984-02-09 | Schülke & Mayr GmbH, 2000 Hamburg | Mikrobizide mittel |
| DE3333443A1 (de) * | 1983-09-16 | 1985-03-28 | B. Braun Melsungen Ag, 3508 Melsungen | Desinfektionsmittel-konzentrate auf der basis von kurzkettigen fettsaeuren |
| US4719235A (en) * | 1984-10-16 | 1988-01-12 | Gerald N. Kern | Methods and compositions for treating viral infection |
| US4738847A (en) * | 1985-01-14 | 1988-04-19 | Kimberly-Clark Corporation | Multi-ply virucidal product |
| US4885310A (en) * | 1985-05-09 | 1989-12-05 | Gerald N. Kern | Anti-fungal methods and agent |
| US4717737A (en) * | 1985-06-05 | 1988-01-05 | Gerald N. Kern | Anti-bacterial methods and agent |
| US4752617A (en) * | 1985-06-05 | 1988-06-21 | Gerald N. Kern | Anti-bacterial methods and agents |
| IT1213453B (it) * | 1985-08-02 | 1989-12-20 | Merz & Co Gmbh & Co | Composizione farmaceutica. |
| US4615937A (en) * | 1985-09-05 | 1986-10-07 | The James River Corporation | Antimicrobially active, non-woven web used in a wet wiper |
| US4740398A (en) * | 1985-09-30 | 1988-04-26 | James River Corporation | Binder catalyst for an antimicrobially active, non-woven web |
| US4737405A (en) * | 1985-09-30 | 1988-04-12 | James River Corporation | Binder catalyst for an antimicrobially active, non-woven web |
| DE3622089A1 (de) * | 1986-07-02 | 1988-01-07 | Krueger Gmbh & Co Kg | Viruzides mittel mit breitbandwirkung |
| US4732797A (en) * | 1987-02-27 | 1988-03-22 | James River Corporation | Wet wiper natural acid preservation system |
| US4997851A (en) * | 1987-12-31 | 1991-03-05 | Isaacs Charles E | Antiviral and antibacterial activity of fatty acids and monoglycerides |
| DK311489A (da) * | 1989-06-23 | 1990-12-24 | John Ejnar Andersen | Metode til at bekaempe virus-svampe og bakteriesygdomme hos mennesker og dyr |
| US5244922A (en) * | 1990-09-04 | 1993-09-14 | Burzynski Stanislaw R | Methods for treating viral infections |
| DE4031664A1 (de) * | 1990-10-05 | 1992-04-09 | Heimo Wessollek | Mittel zur verringerung des bakterienwachstums in wasser |
| US5489433A (en) * | 1991-01-04 | 1996-02-06 | Safe-Tee Chemical Products Company | Environmentally safe insecticide |
| US5665307A (en) * | 1991-03-27 | 1997-09-09 | Fresenius Ag | Aqueous disinfecting agent |
| DE4200066C2 (de) * | 1991-03-27 | 1994-09-15 | Fresenius Ag | Verwendung eines wäßrigen zitronensäurehaltigen Desinfektionsmittels zur Inaktivierung von Hepatitis-B-Viren |
| US5234719A (en) * | 1991-06-04 | 1993-08-10 | Ecolab Inc. | Food additive sanitizing compositions |
| NZ240355A (en) * | 1991-06-04 | 1994-09-27 | Ecolab Inc | Sanitising composition comprising sorbic and benzoic acids |
| JPH06510547A (ja) * | 1992-07-06 | 1994-11-24 | コミスサローバ，イリナ アレクセエフナ | 抗アルコール活性を有し、エネルギー代謝と胃粘膜の酸を生成し分泌する機能とを刺激し、放射能防御活性と抗コレラ活性を有する医薬組成物 |
| CA2142605A1 (en) * | 1992-08-27 | 1994-03-17 | Saeed Fereshtehkhou | Tissue paper treated with nonionic softeners that are biodegradable |
| DE4229713B4 (de) * | 1992-09-05 | 2005-06-23 | Schiller, Friedrich, Prof. Dr.med.habil. | Lippencreme |
| US5436008A (en) * | 1992-12-11 | 1995-07-25 | Ecolab Inc. | Sanitizing compositions |
| US5683724A (en) * | 1993-03-17 | 1997-11-04 | Ecolab Inc. | Automated process for inhibition of microbial growth in aqueous food transport or process streams |
| US5409713A (en) * | 1993-03-17 | 1995-04-25 | Ecolab Inc. | Process for inhibition of microbial growth in aqueous transport streams |
| US6238682B1 (en) * | 1993-12-13 | 2001-05-29 | The Procter & Gamble Company | Anhydrous skin lotions having antimicrobial components for application to tissue paper products which mitigate the potential for skin irritation |
| US5830487A (en) * | 1996-06-05 | 1998-11-03 | The Procter & Gamble Company | Anti-viral, anhydrous, and mild skin lotions for application to tissue paper products |
| US6302968B1 (en) | 1994-04-19 | 2001-10-16 | Ecolab Inc. | Precarboxylic acid rinse method |
| US5578134A (en) * | 1994-04-19 | 1996-11-26 | Ecolab Inc. | Method of sanitizing and destaining tableware |
| US6257253B1 (en) | 1994-04-19 | 2001-07-10 | Ecolab Inc. | Percarboxylic acid rinse method |
| DE4435188A1 (de) * | 1994-09-30 | 1996-04-04 | Beiersdorf Ag | Verwendung von alpha,omega-Alkandicarbonsäuren gegen Superinfektionen |
| SE9403541L (sv) * | 1994-10-14 | 1996-04-15 | Sven Moberg | Antimikrobiell komposition |
| JPH09173020A (ja) * | 1995-12-28 | 1997-07-08 | Shiro Tanaka | クエン酸・リンゴ酸カルシウムの可溶性濃厚カルシウム凍結品／冷蔵品およびその製造法 |
| DE19800006A1 (de) * | 1998-01-02 | 1999-07-08 | Banda Fruehbauer Brigitte | Taschentuch und Verfahren zu seiner Herstellung |
| EP0966883A1 (de) * | 1998-06-26 | 1999-12-29 | The Procter & Gamble Company | Verwendung einer antimikrobiellen Verbindung zur Desinfektion |
| EP1034701A1 (de) * | 1999-03-09 | 2000-09-13 | Arconia GmbH | Flächiges Gebilde und Verfahren sowie Mittel zu seiner Herstellung |
| US6187332B1 (en) | 1999-06-14 | 2001-02-13 | Wisconsin Alumni Research Foundation | Acidic buffered nasal spray |
| US20020064542A1 (en) * | 1999-06-29 | 2002-05-30 | George Endel Deckner | Tissue products utilizing water soluble films as carriers for antiviral compositions and process for making |
| US6860967B2 (en) | 2001-01-19 | 2005-03-01 | Sca Hygiene Products Gmbh | Tissue paper penetrated with softening lotion |
| US6905697B2 (en) | 2001-01-19 | 2005-06-14 | Sca Hygiene Products Gmbh | Lotioned fibrous web having a short water absorption time |
| DE10223934B4 (de) | 2002-05-29 | 2009-04-09 | Schülke & Mayr GmbH | Verwendung eines Desinfektionsmittels zur Inaktivierung von Hepatitis B-Virus |
| DE10248276A1 (de) * | 2002-10-16 | 2004-05-06 | Predinal Gmbh | Mittel zur Inaktivierung infektiöser Prionen, auf Flächen Instrumenten und in kontaminierten Flüssigkeiten |
| DE10317931A1 (de) | 2003-04-17 | 2004-11-11 | Schülke & Mayr GmbH | Chemothermisches Desinfektionsverfahren |
| US20050271710A1 (en) | 2004-06-04 | 2005-12-08 | Argo Brian P | Antimicrobial tissue products with reduced skin irritation potential |
| WO2008045860A2 (en) * | 2006-10-10 | 2008-04-17 | Michael Lynch | Methods of inactivating viruses |
| DE102009038213A1 (de) | 2009-08-20 | 2011-09-08 | Fresenius Medical Care Deutschland Gmbh | Desinfektionsmittel, dessen Verwendung und Desinfektionsverfahren |
| EP3231939A1 (de) | 2016-04-11 | 2017-10-18 | Fuhrmann, Uwe | Mehrlagiges papiertaschentuch zur reduzierung der übertragung von krankheitserregern |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH323778A (de) * | 1953-05-21 | 1957-08-15 | Schuelke & Mayr Gmbh | Desinfektionsmittel |
| DE1105549B (de) * | 1957-07-06 | 1961-04-27 | Johannes Roedger Dr Med | Desinfizierende Wasch- und Reinigungsmittel |
| US3141821A (en) * | 1959-03-17 | 1964-07-21 | Lehn & Fink Products Corp | Synergistic combination of alkyl sulfonates, alkylaryl sulfonates and topical antibacterial agents for local antisepsis |
| US3650964A (en) * | 1968-05-13 | 1972-03-21 | Basf Wyandotte Corp | Low foam anionic acid sanitizer compositions |
| DE1924490A1 (de) * | 1968-05-14 | 1969-11-20 | Heinz Co H J | Verfahren zum Herstellen von trockenem Tomatenkonzentrat und gemaess diesem Verfahren hergestelltes Tomatenkonzentrat |
| US3567118A (en) * | 1968-09-05 | 1971-03-02 | Nat Patent Dev Corp | Entrapped essences in dry composite fiber base products giving a strong fragrance when wet in water |
| DE2312280A1 (de) * | 1973-03-13 | 1974-09-26 | Henkel & Cie Gmbh | Verwendung von beta-hydroxycarbonsaeuren als antimikrobielle substanzen |
| US3969258A (en) * | 1974-10-10 | 1976-07-13 | Pennwalt Corporation | Low foaming acid-anionic surfactant sanitizer compositions |
| US4045364A (en) * | 1975-11-24 | 1977-08-30 | American Cyanamid Company | Iodophor soap tissues |
| GB1505388A (en) * | 1975-11-27 | 1978-03-30 | Bp Chem Int Ltd | Acid salt solutions |
| FR2370471A1 (fr) * | 1976-11-13 | 1978-06-09 | Kohler Valentin | Agents a base d'acide glucarique possedant une activite pharmaceutique et/ou anti-microbienne |
| IL58009A (en) * | 1978-08-14 | 1982-11-30 | Sterling Drug Inc | Process and compositions comprising glutaric acid for neutralizing or destroying viruses |
| EP0049354A3 (de) * | 1980-09-08 | 1983-02-23 | Sterling Drug Inc. | Mischung zur therapeutischen, antiviralen Verwendung sowie Artikel und Packungen, die diese Mischung enthalten |
| JPS5817167B2 (ja) * | 1980-11-10 | 1983-04-05 | 持田製薬株式会社 | 抗ウイルス作用を有する医薬組成物 |
-
1982
- 1982-07-14 DK DK315482A patent/DK315482A/da not_active Application Discontinuation
- 1982-07-15 CA CA000407348A patent/CA1188225A/en not_active Expired
- 1982-07-16 NL NL8202885A patent/NL8202885A/nl not_active Application Discontinuation
- 1982-07-16 IT IT8248833A patent/IT1212049B/it active
- 1982-07-19 KR KR828203196A patent/KR870002047B1/ko active
- 1982-07-19 FI FI822542A patent/FI822542L/fi not_active Application Discontinuation
- 1982-07-19 GR GR68791A patent/GR76879B/el unknown
- 1982-07-19 PH PH27588A patent/PH21282A/en unknown
- 1982-07-19 SE SE8204372A patent/SE8204372L/ unknown
- 1982-07-20 AU AU86210/82A patent/AU554127B2/en not_active Ceased
- 1982-07-20 FR FR8212634A patent/FR2509577B1/fr not_active Expired
- 1982-07-20 LU LU84282A patent/LU84282A1/fr unknown
- 1982-07-20 GB GB08220966A patent/GB2103089B/en not_active Expired
- 1982-07-20 DE DE3227126A patent/DE3227126C2/de not_active Revoked
Also Published As
| Publication number | Publication date |
|---|---|
| FR2509577B1 (fr) | 1988-06-03 |
| SE8204372D0 (sv) | 1982-07-19 |
| DE3227126C2 (de) | 1993-11-18 |
| FI822542L (fi) | 1983-01-21 |
| KR870002047B1 (ko) | 1987-12-03 |
| FI822542A0 (fi) | 1982-07-19 |
| DE3227126A1 (de) | 1983-02-03 |
| AU554127B2 (en) | 1986-08-07 |
| PH21282A (en) | 1987-09-28 |
| SE8204372L (sv) | 1983-01-21 |
| AU8621082A (en) | 1983-01-27 |
| GB2103089B (en) | 1986-03-12 |
| IT1212049B (it) | 1989-11-08 |
| GR76879B (de) | 1984-09-04 |
| GB2103089A (en) | 1983-02-16 |
| KR840000243A (ko) | 1984-02-18 |
| CA1188225A (en) | 1985-06-04 |
| IT8248833A0 (it) | 1982-07-16 |
| NL8202885A (nl) | 1983-02-16 |
| DK315482A (da) | 1983-01-21 |
| FR2509577A1 (fr) | 1983-01-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| LU84282A1 (fr) | Procede,composition et produit virulicides | |
| US4828912A (en) | Virucidal product having virucidal and/or germicidal properties | |
| US4897304A (en) | Virucidal composition, the method of use and the product therefor | |
| US4975217A (en) | Virucidal composition, the method of use and the product therefor | |
| TWI439274B (zh) | 抗病毒方法 | |
| JP5829293B2 (ja) | カリシウイルス不活化方法 | |
| JP2799210B2 (ja) | Ａｉｄｓ伝播阻止組成物 | |
| US20090061019A1 (en) | Disinfectant compositions and methods of use thereof | |
| JP2010505964A (ja) | ウイルスを不活性化する方法 | |
| JP5571577B2 (ja) | Ａ型インフルエンザウイルス属のエンベロープウイルスに対する抗ウイルス性衛生用繊維製品 | |
| JP2009173768A (ja) | 便座用除菌洗浄剤組成物およびこれを含有する除菌洗浄材、ならびにこれらを用いた除菌洗浄方法 | |
| US20190216085A1 (en) | Preservative Composition for Wet Wipes | |
| EP0478445B1 (de) | Zusammensetzung zur Reinigung und Entseuchung, insbesondere von chirurgischen Instrumenten | |
| JPH10504322A (ja) | 汚染された環境を消毒するための方法および組成物 | |
| WO2006097758A2 (en) | Antimicrobial composition | |
| WO1990006677A1 (en) | Virucidal low toxicity compositions | |
| DK2471559T3 (en) | Antiviral method | |
| JPH0476967B2 (de) | ||
| US20230399581A1 (en) | Detergent composition | |
| WO2020222123A1 (en) | Sprayable antimicrobial coatings for wound treatments | |
| BE893895A (fr) | Procede, composition et produit pour agir contre les virus | |
| CN115103592A (zh) | 通用制剂 | |
| HU226400B1 (en) | Disinfectant compound based on didecyl dimethyl ammonium bromide carbamide clathrate | |
| RU2173337C1 (ru) | Дезинфицирующе-моющий раствор | |
| JPH0563446B2 (de) |