LU82728A1 - 6-(pyridinyl)-3(2h)pyridazinones,leur preparation et leur utilisation therapeutique - Google Patents

6-(pyridinyl)-3(2h)pyridazinones,leur preparation et leur utilisation therapeutique Download PDF

Info

Publication number
LU82728A1
LU82728A1 LU82728A LU82728A LU82728A1 LU 82728 A1 LU82728 A1 LU 82728A1 LU 82728 A LU82728 A LU 82728A LU 82728 A LU82728 A LU 82728A LU 82728 A1 LU82728 A1 LU 82728A1
Authority
LU
Luxembourg
Prior art keywords
pyridinyl
pyridazinone
dihydro
methyl
acid
Prior art date
Application number
LU82728A
Other languages
English (en)
French (fr)
Original Assignee
Sterling Drug Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc
Publication of LU82728A1 publication Critical patent/LU82728A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/57—Nitriles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
LU82728A 1979-08-30 1980-08-26 6-(pyridinyl)-3(2h)pyridazinones,leur preparation et leur utilisation therapeutique LU82728A1 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US7106579A 1979-08-30 1979-08-30
US7106579 1979-08-30
US06/144,576 US4304777A (en) 1979-08-30 1980-04-28 6-(Pyridinyl)-3(2H)-pyridazinones and their use as cardiotonics
US14457680 1980-04-28

Publications (1)

Publication Number Publication Date
LU82728A1 true LU82728A1 (fr) 1981-03-24

Family

ID=26751794

Family Applications (1)

Application Number Title Priority Date Filing Date
LU82728A LU82728A1 (fr) 1979-08-30 1980-08-26 6-(pyridinyl)-3(2h)pyridazinones,leur preparation et leur utilisation therapeutique

Country Status (19)

Country Link
US (1) US4304777A (it)
AR (1) AR226704A1 (it)
AT (1) ATA427680A (it)
AU (1) AU532052B2 (it)
CA (1) CA1155848A (it)
DE (1) DE3032137A1 (it)
DK (1) DK364880A (it)
ES (1) ES494559A0 (it)
FI (1) FI802676A (it)
FR (1) FR2464264A1 (it)
GB (1) GB2057438B (it)
IL (1) IL60918A (it)
IT (1) IT1141012B (it)
LU (1) LU82728A1 (it)
NL (1) NL8004815A (it)
NO (1) NO802507L (it)
NZ (1) NZ194811A (it)
PT (1) PT71736B (it)
SE (1) SE8005946L (it)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4486431A (en) * 1981-01-14 1984-12-04 Sterling Drug Inc. Cardiotonic use of 4,5-dihydro-6-(4-pyridinyl)-3(2H)-pyridazinones
IL62679A0 (en) * 1980-04-28 1981-06-29 Sterling Drug Inc 4,5-dihydro-3(2h)-pyridazinone derivatives,their preparation and pharmaceutical compositions containing them
US4404203A (en) 1981-05-14 1983-09-13 Warner-Lambert Company Substituted 6-phenyl-3(2H)-pyridazinones useful as cardiotonic agents
US4397854A (en) 1981-05-14 1983-08-09 Warner-Lambert Company Substituted 6-phenyl-3(2H)-pyridazinones useful as cardiotonic agents
US4353905A (en) 1981-09-17 1982-10-12 Warner-Lambert Company Substituted 4,5-dihydro-6-[4-(1H-imidazol-1-yl)phenyl]-3(2H)-pyridazinones and 6-[4-(1H-imidazol-1-yl)phenyl]-3(2H)-pyridazinones
IE54598B1 (en) * 1981-11-12 1989-12-06 Ici Plc Pharmaceutically-active pyridylvinylpyridazinones
US4591591A (en) * 1984-03-08 1986-05-27 Eli Lilly And Company Pyridazinone derivatives as inotropic agents
US4647564A (en) * 1984-05-14 1987-03-03 Eli Lilly And Company Inotropic agents
US4617302A (en) * 1984-10-15 1986-10-14 Eli Lilly And Company Inotropic agents
US4631279A (en) * 1984-10-15 1986-12-23 Eli Lilly And Company 6-(pyridinylphenyl)dihydropyridazinones as inotropic agents
HU195645B (en) * 1985-10-30 1988-06-28 Gyogyszerkutato Intezet Process for preparing novel 3(2h)-pyridazinone derivatives and pharmaceutical compositions comprising the same
DE3626865A1 (de) * 1986-08-08 1988-02-11 Boehringer Mannheim Gmbh Neue pyridazinon-derivate, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
GB9015764D0 (en) * 1990-07-18 1990-09-05 Fujisawa Pharmaceutical Co Pyrazolopyridine compound and processes for preparation thereof
CN1038249C (zh) * 1991-08-28 1998-05-06 罗姆和哈斯公司 含有二氢哒嗪酮及其相关化合物的杀菌组合物
EP3365335B1 (en) 2015-10-23 2024-02-14 Array Biopharma, Inc. 2-aryl- and 2-heteroaryl-substituted 2-pyridazin-3(2h)-one compounds as inhibitors of fgfr tyrosine kinases

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3822260A (en) * 1970-10-09 1974-07-02 American Cyanamid Co 6-(cyanophenyl)-4,5-dihydro-3(2h)-pyridazinones
US3812256A (en) * 1971-06-08 1974-05-21 American Cyanamid Co Novel method for lowering blood pressure in mammals
US3746712A (en) * 1971-06-08 1973-07-17 A Ross 6-(substituted-phenyl)-5-methyl-4,5-dihydro-3(2h)-pyridazinones
US4004009A (en) * 1975-07-31 1977-01-18 Sandoz, Inc. Antihypertensive aryl pyrazolo[4,3-c]pyridazinones
US4004012A (en) * 1975-10-14 1977-01-18 Sterling Drug Inc. 3-Cyano-5-(pyridinyl)-2(1H)-pyridinones
US4072746A (en) * 1975-10-14 1978-02-07 Sterling Drug Inc. 3-Amino-5-(pyridinyl)-2(1H)-pyridinones

Also Published As

Publication number Publication date
GB2057438A (en) 1981-04-01
AU532052B2 (en) 1983-09-15
AR226704A1 (es) 1982-08-13
IT8024230A0 (it) 1980-08-20
PT71736A (en) 1980-09-01
FR2464264A1 (fr) 1981-03-06
IT1141012B (it) 1986-10-01
IL60918A0 (en) 1980-10-26
DK364880A (da) 1981-03-01
AU6192880A (en) 1981-03-05
GB2057438B (en) 1983-09-07
IL60918A (en) 1983-11-30
FI802676A (fi) 1981-03-01
PT71736B (en) 1981-06-15
CA1155848A (en) 1983-10-25
DE3032137A1 (de) 1981-03-19
NO802507L (no) 1981-03-02
NZ194811A (en) 1984-05-31
NL8004815A (nl) 1981-03-03
ES8107215A1 (es) 1981-08-16
US4304777A (en) 1981-12-08
SE8005946L (sv) 1981-03-02
ES494559A0 (es) 1981-08-16
ATA427680A (de) 1983-12-15

Similar Documents

Publication Publication Date Title
CH619936A5 (it)
LU82728A1 (fr) 6-(pyridinyl)-3(2h)pyridazinones,leur preparation et leur utilisation therapeutique
FR2553767A1 (fr) 1-pyridinyl-2-(dialkyl-amino) ethenyl alkyl cetones et leur procede de preparation
LU83259A1 (fr) Imidazopyridines,leur preparation et leur utilisation comme agents cardiotiniques
LU83214A1 (fr) Derives de pyrazolopyridine,leur preparation et leur utilisation comme agents cardiotoniques
US4298609A (en) 4,5-Dihydro-6-(4-pyridinyl)-3-pyridazinol and salts, their preparation and use as blood pressure lowering agents
US4331671A (en) 5-(Pyridinyl)-1H-benzimidazoles and 1-hydroxy-6-(pyridinyl)-1H-benzimidazoles and their cardiotonic use
EP0150205A1 (en) ad(pyridinyl)-2-pyrimidinyl bdureas useful as cardiotonics and preparation thereof
BE884859A (fr) 6-(pyridinyl)-3 (2h)pyridazinones, leur preparation et leur utilisation therapeutique
US4304775A (en) 3-Hydrazino-6-(pyridinyl) pyridazines and cardiotonic use thereof
LU83032A1 (fr) 3-acylamino-5(pyridinyl)-2(1h)-pyridinones,leur preparation et leur utilisation comme agents cardiotoniques
US4337253A (en) 4,5-Dihydro-2-methyl-6-(4-pyridinyl)-3(2H)-pyridazinone and its use as a cardiotonic
US4346221A (en) Preparation of 4-amino-6-(pyridinyl)-3(2H)-pyridazinones from 6-(pyridinyl)-3(2H)-pyridazinones
US4486431A (en) Cardiotonic use of 4,5-dihydro-6-(4-pyridinyl)-3(2H)-pyridazinones
US4590194A (en) 3-[methyl or dimethyl)amino]-6-(pyridinyl)pyridazines and their cardiotonic use
FR2496659A1 (fr) Derives de 1,2 dihydro-5(pyridinyl)nicotinamide, leur preparation et leur utilisation comme agents cardiotoniques et intermediaires
US4305943A (en) 4-Amino-6-(pyridinyl)-3(2H)-pyridazinones and their use as cardiotonics
LU83396A1 (fr) Compositions cardiotoniques contenant des aminophenylpyridines,nouvelles aminophenylpyridines et leur preparation
FR2465722A1 (fr) 3-(hydroxy ou hydroxymethyl)-5-(4-pyridinyl)-2(1h)-pyridinones, leur preparation et leur utilisation comme agents cardiotoniques
US4354026A (en) 3-Chloro-6-(pyridinyl)-pyridazines
LU83322A1 (fr) 6-(pyridinyl)-3(2h)-pyridazinones 4-substitutees,leur preparation,leur utilisation comme agents cardiotoniques,et composes intermediaires.
LU83320A1 (fr) 4,5-dihydro-6-(pyridinyl)-3(2h)-pyridazinones,leur preparation et leur utilisation comme agents cardiotoniques
BE886574A (fr) 6-(pyridinyl)-pyridazines, leur preparation et leur utilisation therapeutique
LU83498A1 (fr) Pyridinyl-amino-phenols,leur preparation et leur utilisation comme agents cardiotoniques
FR2478098A1 (fr) Pyrazolopyridinones et pyridinylnicotinates, leur preparation et leur utilisation comme agents cardiotoniques