PT71736B - Process for the preparation of 6-pyridazinones useful as cardiotonics agents - Google Patents
Process for the preparation of 6-pyridazinones useful as cardiotonics agentsInfo
- Publication number
- PT71736B PT71736B PT71736A PT7173680A PT71736B PT 71736 B PT71736 B PT 71736B PT 71736 A PT71736 A PT 71736A PT 7173680 A PT7173680 A PT 7173680A PT 71736 B PT71736 B PT 71736B
- Authority
- PT
- Portugal
- Prior art keywords
- cardiotonics
- pyridazinones
- agents
- useful
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/57—Nitriles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7106579A | 1979-08-30 | 1979-08-30 | |
| US06/144,576 US4304777A (en) | 1979-08-30 | 1980-04-28 | 6-(Pyridinyl)-3(2H)-pyridazinones and their use as cardiotonics |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT71736A PT71736A (en) | 1980-09-01 |
| PT71736B true PT71736B (en) | 1981-06-15 |
Family
ID=26751794
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT71736A PT71736B (en) | 1979-08-30 | 1980-08-25 | Process for the preparation of 6-pyridazinones useful as cardiotonics agents |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US4304777A (pt) |
| AR (1) | AR226704A1 (pt) |
| AT (1) | ATA427680A (pt) |
| AU (1) | AU532052B2 (pt) |
| CA (1) | CA1155848A (pt) |
| DE (1) | DE3032137A1 (pt) |
| DK (1) | DK364880A (pt) |
| ES (1) | ES494559A0 (pt) |
| FI (1) | FI802676A (pt) |
| FR (1) | FR2464264A1 (pt) |
| GB (1) | GB2057438B (pt) |
| IL (1) | IL60918A (pt) |
| IT (1) | IT1141012B (pt) |
| LU (1) | LU82728A1 (pt) |
| NL (1) | NL8004815A (pt) |
| NO (1) | NO802507L (pt) |
| NZ (1) | NZ194811A (pt) |
| PT (1) | PT71736B (pt) |
| SE (1) | SE8005946L (pt) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4486431A (en) * | 1981-01-14 | 1984-12-04 | Sterling Drug Inc. | Cardiotonic use of 4,5-dihydro-6-(4-pyridinyl)-3(2H)-pyridazinones |
| IL62679A0 (en) * | 1980-04-28 | 1981-06-29 | Sterling Drug Inc | 4,5-dihydro-3(2h)-pyridazinone derivatives,their preparation and pharmaceutical compositions containing them |
| US4404203A (en) | 1981-05-14 | 1983-09-13 | Warner-Lambert Company | Substituted 6-phenyl-3(2H)-pyridazinones useful as cardiotonic agents |
| US4397854A (en) | 1981-05-14 | 1983-08-09 | Warner-Lambert Company | Substituted 6-phenyl-3(2H)-pyridazinones useful as cardiotonic agents |
| US4353905A (en) | 1981-09-17 | 1982-10-12 | Warner-Lambert Company | Substituted 4,5-dihydro-6-[4-(1H-imidazol-1-yl)phenyl]-3(2H)-pyridazinones and 6-[4-(1H-imidazol-1-yl)phenyl]-3(2H)-pyridazinones |
| IE54598B1 (en) * | 1981-11-12 | 1989-12-06 | Ici Plc | Pharmaceutically-active pyridylvinylpyridazinones |
| US4591591A (en) * | 1984-03-08 | 1986-05-27 | Eli Lilly And Company | Pyridazinone derivatives as inotropic agents |
| US4647564A (en) * | 1984-05-14 | 1987-03-03 | Eli Lilly And Company | Inotropic agents |
| US4617302A (en) * | 1984-10-15 | 1986-10-14 | Eli Lilly And Company | Inotropic agents |
| US4631279A (en) * | 1984-10-15 | 1986-12-23 | Eli Lilly And Company | 6-(pyridinylphenyl)dihydropyridazinones as inotropic agents |
| HU195645B (en) * | 1985-10-30 | 1988-06-28 | Gyogyszerkutato Intezet | Process for preparing novel 3(2h)-pyridazinone derivatives and pharmaceutical compositions comprising the same |
| DE3626865A1 (de) * | 1986-08-08 | 1988-02-11 | Boehringer Mannheim Gmbh | Neue pyridazinon-derivate, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
| GB9015764D0 (en) * | 1990-07-18 | 1990-09-05 | Fujisawa Pharmaceutical Co | Pyrazolopyridine compound and processes for preparation thereof |
| CN1038249C (zh) * | 1991-08-28 | 1998-05-06 | 罗姆和哈斯公司 | 含有二氢哒嗪酮及其相关化合物的杀菌组合物 |
| EP3365335B1 (en) | 2015-10-23 | 2024-02-14 | Array Biopharma, Inc. | 2-aryl- and 2-heteroaryl-substituted 2-pyridazin-3(2h)-one compounds as inhibitors of fgfr tyrosine kinases |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3822260A (en) * | 1970-10-09 | 1974-07-02 | American Cyanamid Co | 6-(cyanophenyl)-4,5-dihydro-3(2h)-pyridazinones |
| US3812256A (en) * | 1971-06-08 | 1974-05-21 | American Cyanamid Co | Novel method for lowering blood pressure in mammals |
| US3746712A (en) * | 1971-06-08 | 1973-07-17 | A Ross | 6-(substituted-phenyl)-5-methyl-4,5-dihydro-3(2h)-pyridazinones |
| US4004009A (en) * | 1975-07-31 | 1977-01-18 | Sandoz, Inc. | Antihypertensive aryl pyrazolo[4,3-c]pyridazinones |
| US4004012A (en) * | 1975-10-14 | 1977-01-18 | Sterling Drug Inc. | 3-Cyano-5-(pyridinyl)-2(1H)-pyridinones |
| US4072746A (en) * | 1975-10-14 | 1978-02-07 | Sterling Drug Inc. | 3-Amino-5-(pyridinyl)-2(1H)-pyridinones |
-
1980
- 1980-04-28 US US06/144,576 patent/US4304777A/en not_active Expired - Lifetime
- 1980-08-20 IT IT24230/80A patent/IT1141012B/it active
- 1980-08-21 GB GB8027262A patent/GB2057438B/en not_active Expired
- 1980-08-21 FR FR8018304A patent/FR2464264A1/fr active Pending
- 1980-08-22 AT AT0427680A patent/ATA427680A/de not_active Application Discontinuation
- 1980-08-22 NO NO802507A patent/NO802507L/no unknown
- 1980-08-25 SE SE8005946A patent/SE8005946L/xx not_active Application Discontinuation
- 1980-08-25 PT PT71736A patent/PT71736B/pt unknown
- 1980-08-25 FI FI802676A patent/FI802676A/fi not_active Application Discontinuation
- 1980-08-26 AR AR282296A patent/AR226704A1/es active
- 1980-08-26 LU LU82728A patent/LU82728A1/fr unknown
- 1980-08-26 NL NL8004815A patent/NL8004815A/nl not_active Application Discontinuation
- 1980-08-26 DE DE19803032137 patent/DE3032137A1/de not_active Withdrawn
- 1980-08-26 IL IL60918A patent/IL60918A/xx unknown
- 1980-08-26 DK DK364880A patent/DK364880A/da not_active Application Discontinuation
- 1980-08-28 ES ES494559A patent/ES494559A0/es active Granted
- 1980-08-29 NZ NZ194811A patent/NZ194811A/en unknown
- 1980-08-29 CA CA000359361A patent/CA1155848A/en not_active Expired
- 1980-09-01 AU AU61928/80A patent/AU532052B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| GB2057438A (en) | 1981-04-01 |
| AU532052B2 (en) | 1983-09-15 |
| AR226704A1 (es) | 1982-08-13 |
| IT8024230A0 (it) | 1980-08-20 |
| PT71736A (en) | 1980-09-01 |
| FR2464264A1 (fr) | 1981-03-06 |
| IT1141012B (it) | 1986-10-01 |
| IL60918A0 (en) | 1980-10-26 |
| DK364880A (da) | 1981-03-01 |
| AU6192880A (en) | 1981-03-05 |
| GB2057438B (en) | 1983-09-07 |
| IL60918A (en) | 1983-11-30 |
| FI802676A (fi) | 1981-03-01 |
| CA1155848A (en) | 1983-10-25 |
| DE3032137A1 (de) | 1981-03-19 |
| NO802507L (no) | 1981-03-02 |
| LU82728A1 (fr) | 1981-03-24 |
| NZ194811A (en) | 1984-05-31 |
| NL8004815A (nl) | 1981-03-03 |
| ES8107215A1 (es) | 1981-08-16 |
| US4304777A (en) | 1981-12-08 |
| SE8005946L (sv) | 1981-03-02 |
| ES494559A0 (es) | 1981-08-16 |
| ATA427680A (de) | 1983-12-15 |
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