LU82677A1 - Nouveaux derives de la 3,4,5-trimethoxy cinnamoyle piperazine,leur procede de preparation et leur application en therapeutique - Google Patents

Nouveaux derives de la 3,4,5-trimethoxy cinnamoyle piperazine,leur procede de preparation et leur application en therapeutique Download PDF

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Publication number
LU82677A1
LU82677A1 LU82677A LU82677A LU82677A1 LU 82677 A1 LU82677 A1 LU 82677A1 LU 82677 A LU82677 A LU 82677A LU 82677 A LU82677 A LU 82677A LU 82677 A1 LU82677 A1 LU 82677A1
Authority
LU
Luxembourg
Prior art keywords
formula
group
compound
methyl
compounds
Prior art date
Application number
LU82677A
Other languages
English (en)
French (fr)
Inventor
Gerard Moinet
Alain Lacour
Guy Bourgery
Bernard Pourrias
Anne M Ruch
Original Assignee
Delalande Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Delalande Sa filed Critical Delalande Sa
Publication of LU82677A1 publication Critical patent/LU82677A1/fr

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182Radicals derived from carboxylic acids
    • C07D295/185Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/54Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition of compounds containing doubly bound oxygen atoms, e.g. esters
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/12Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/24Ethers with hydroxy compounds containing no oxirane rings with polyhydroxy compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D319/00Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/101,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/141,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C07D319/161,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D319/18Ethylenedioxybenzenes, not substituted on the hetero ring

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
LU82677A 1979-08-03 1980-08-01 Nouveaux derives de la 3,4,5-trimethoxy cinnamoyle piperazine,leur procede de preparation et leur application en therapeutique LU82677A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR7919990A FR2462432A2 (fr) 1979-08-03 1979-08-03 Nouveaux derives de la 3,4,5 trimethoxy cinnamoyle piperazine, leur procede de preparation et leur application en therapeutique
FR7919990 1979-08-03

Publications (1)

Publication Number Publication Date
LU82677A1 true LU82677A1 (fr) 1982-05-10

Family

ID=9228620

Family Applications (1)

Application Number Title Priority Date Filing Date
LU82677A LU82677A1 (fr) 1979-08-03 1980-08-01 Nouveaux derives de la 3,4,5-trimethoxy cinnamoyle piperazine,leur procede de preparation et leur application en therapeutique

Country Status (14)

Country Link
JP (1) JPS5626885A (el)
AU (1) AU6100380A (el)
BE (1) BE884602R (el)
CA (1) CA1155121A (el)
CH (1) CH646694A5 (el)
DE (1) DE3028912A1 (el)
ES (2) ES8107195A1 (el)
FR (1) FR2462432A2 (el)
GB (1) GB2057433B (el)
GR (1) GR68073B (el)
LU (1) LU82677A1 (el)
NL (1) NL8004434A (el)
SE (1) SE8005300L (el)
ZA (1) ZA804709B (el)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2507604A2 (fr) * 1977-04-19 1982-12-17 Delalande Sa Nouvelles trimethoxy-3,4,5 cinnamoyle piperazines, leur procede de preparation et leur application en therapeutique
US4567264A (en) * 1983-05-18 1986-01-28 Syntex (U.S.A.) Inc. Cardioselective aryloxy- and arylthio- hydroxypropylene-piperazinyl acetanilides which affect calcium entry
US4558129A (en) * 1983-05-18 1985-12-10 Syntex (U.S.A.) Inc. Benzodioxanyl-hydroxyethylene-piperazinyl acetanilides which effect calcium entry and β-blockade
US4499100A (en) * 1983-05-18 1985-02-12 Syntex (U.S.A.) Inc. Benzodioxanyl-hydroxyethyleneamino-piperidinyl acetanilides, ketones, esters and carbamates which effect immunity and calcium entry and β-blockade
US4997836A (en) * 1988-11-11 1991-03-05 Takeda Chemical Industries, Ltd. Trisubstituted piperazine compounds, their production and use
US6514996B2 (en) 1995-05-19 2003-02-04 Kyowa Hakko Kogyo Co., Ltd. Derivatives of benzofuran or benzodioxole
EP0943613A4 (en) * 1996-11-19 2002-07-10 Kyowa Hakko Kogyo Kk HETEROCYCLIC COMPOUNDS CONTAINING OXYGEN
WO2008144933A1 (en) 2007-05-29 2008-12-04 Université de Montréal Cinnamoyl inhibitors of transglutaminase

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2387971A1 (fr) * 1977-04-19 1978-11-17 Delalande Sa Nouvelles trimethoxy cinnamoyles piperazines, leur procede de preparation et leur application en therapeutique

Also Published As

Publication number Publication date
FR2462432A2 (fr) 1981-02-13
SE8005300L (sv) 1981-02-04
BE884602R (fr) 1981-02-02
ES499814A0 (es) 1982-12-16
JPS634827B2 (el) 1988-02-01
ZA804709B (en) 1981-10-28
GB2057433B (en) 1983-08-10
CH646694A5 (fr) 1984-12-14
ES493931A0 (es) 1981-10-01
ES8301944A1 (es) 1982-12-16
AU6100380A (en) 1981-02-05
JPS5626885A (en) 1981-03-16
CA1155121A (en) 1983-10-11
ES8107195A1 (es) 1981-10-01
GB2057433A (en) 1981-04-01
DE3028912A1 (de) 1981-09-24
FR2462432B2 (el) 1983-05-27
GR68073B (el) 1981-10-29
NL8004434A (nl) 1981-02-05

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