NL8004434A - Nieuwe 3,4,5-trimethoxy-cinnamoylpiperazine- verbindingen, werkwijze voor hun bereiding en hun toepassing als geneesmiddelen. - Google Patents

Nieuwe 3,4,5-trimethoxy-cinnamoylpiperazine- verbindingen, werkwijze voor hun bereiding en hun toepassing als geneesmiddelen. Download PDF

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Publication number
NL8004434A
NL8004434A NL8004434A NL8004434A NL8004434A NL 8004434 A NL8004434 A NL 8004434A NL 8004434 A NL8004434 A NL 8004434A NL 8004434 A NL8004434 A NL 8004434A NL 8004434 A NL8004434 A NL 8004434A
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NL
Netherlands
Prior art keywords
formula
group
compound
compounds
sheet
Prior art date
Application number
NL8004434A
Other languages
English (en)
Dutch (nl)
Original Assignee
Delalande Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Delalande Sa filed Critical Delalande Sa
Publication of NL8004434A publication Critical patent/NL8004434A/nl

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/54—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition of compounds containing doubly bound oxygen atoms, e.g. esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/24—Ethers with hydroxy compounds containing no oxirane rings with polyhydroxy compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D319/18—Ethylenedioxybenzenes, not substituted on the hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
NL8004434A 1979-08-03 1980-08-04 Nieuwe 3,4,5-trimethoxy-cinnamoylpiperazine- verbindingen, werkwijze voor hun bereiding en hun toepassing als geneesmiddelen. NL8004434A (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR7919990A FR2462432A2 (fr) 1979-08-03 1979-08-03 Nouveaux derives de la 3,4,5 trimethoxy cinnamoyle piperazine, leur procede de preparation et leur application en therapeutique
FR7919990 1979-08-03

Publications (1)

Publication Number Publication Date
NL8004434A true NL8004434A (nl) 1981-02-05

Family

ID=9228620

Family Applications (1)

Application Number Title Priority Date Filing Date
NL8004434A NL8004434A (nl) 1979-08-03 1980-08-04 Nieuwe 3,4,5-trimethoxy-cinnamoylpiperazine- verbindingen, werkwijze voor hun bereiding en hun toepassing als geneesmiddelen.

Country Status (14)

Country Link
JP (1) JPS5626885A (el)
AU (1) AU6100380A (el)
BE (1) BE884602R (el)
CA (1) CA1155121A (el)
CH (1) CH646694A5 (el)
DE (1) DE3028912A1 (el)
ES (2) ES8107195A1 (el)
FR (1) FR2462432A2 (el)
GB (1) GB2057433B (el)
GR (1) GR68073B (el)
LU (1) LU82677A1 (el)
NL (1) NL8004434A (el)
SE (1) SE8005300L (el)
ZA (1) ZA804709B (el)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2507604A2 (fr) * 1977-04-19 1982-12-17 Delalande Sa Nouvelles trimethoxy-3,4,5 cinnamoyle piperazines, leur procede de preparation et leur application en therapeutique
US4567264A (en) * 1983-05-18 1986-01-28 Syntex (U.S.A.) Inc. Cardioselective aryloxy- and arylthio- hydroxypropylene-piperazinyl acetanilides which affect calcium entry
US4558129A (en) * 1983-05-18 1985-12-10 Syntex (U.S.A.) Inc. Benzodioxanyl-hydroxyethylene-piperazinyl acetanilides which effect calcium entry and β-blockade
US4499100A (en) * 1983-05-18 1985-02-12 Syntex (U.S.A.) Inc. Benzodioxanyl-hydroxyethyleneamino-piperidinyl acetanilides, ketones, esters and carbamates which effect immunity and calcium entry and β-blockade
US4997836A (en) * 1988-11-11 1991-03-05 Takeda Chemical Industries, Ltd. Trisubstituted piperazine compounds, their production and use
US6514996B2 (en) 1995-05-19 2003-02-04 Kyowa Hakko Kogyo Co., Ltd. Derivatives of benzofuran or benzodioxole
EP0943613A4 (en) * 1996-11-19 2002-07-10 Kyowa Hakko Kogyo Kk HETEROCYCLIC COMPOUNDS CONTAINING OXYGEN
WO2008144933A1 (en) 2007-05-29 2008-12-04 Université de Montréal Cinnamoyl inhibitors of transglutaminase

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2387971A1 (fr) * 1977-04-19 1978-11-17 Delalande Sa Nouvelles trimethoxy cinnamoyles piperazines, leur procede de preparation et leur application en therapeutique

Also Published As

Publication number Publication date
FR2462432A2 (fr) 1981-02-13
SE8005300L (sv) 1981-02-04
BE884602R (fr) 1981-02-02
ES499814A0 (es) 1982-12-16
JPS634827B2 (el) 1988-02-01
ZA804709B (en) 1981-10-28
GB2057433B (en) 1983-08-10
CH646694A5 (fr) 1984-12-14
ES493931A0 (es) 1981-10-01
LU82677A1 (fr) 1982-05-10
ES8301944A1 (es) 1982-12-16
AU6100380A (en) 1981-02-05
JPS5626885A (en) 1981-03-16
CA1155121A (en) 1983-10-11
ES8107195A1 (es) 1981-10-01
GB2057433A (en) 1981-04-01
DE3028912A1 (de) 1981-09-24
FR2462432B2 (el) 1983-05-27
GR68073B (el) 1981-10-29

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Legal Events

Date Code Title Description
BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
A85 Still pending on 85-01-01
BV The patent application has lapsed