LU80654A1 - Derives peptidiques,procede pour leur preparation et leur application dans des compositions a usage therapeutique - Google Patents

Derives peptidiques,procede pour leur preparation et leur application dans des compositions a usage therapeutique

Info

Publication number
LU80654A1
LU80654A1 LU80654A LU80654A LU80654A1 LU 80654 A1 LU80654 A1 LU 80654A1 LU 80654 A LU80654 A LU 80654A LU 80654 A LU80654 A LU 80654A LU 80654 A1 LU80654 A1 LU 80654A1
Authority
LU
Luxembourg
Prior art keywords
compositions
preparation
application
therapeutic use
peptide derivatives
Prior art date
Application number
LU80654A
Other languages
English (en)
Inventor
B Morgan
Original Assignee
Reckitt & Colmann Prod Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Reckitt & Colmann Prod Ltd filed Critical Reckitt & Colmann Prod Ltd
Publication of LU80654A1 publication Critical patent/LU80654A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • C07K14/70—Enkephalins
    • C07K14/702—Enkephalins with at least 1 amino acid in D-form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/04—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms
    • C07C275/06—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an acyclic and saturated carbon skeleton
    • C07C275/14—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an acyclic and saturated carbon skeleton being further substituted by nitrogen atoms not being part of nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1016—Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Addiction (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
LU80654A 1977-12-15 1978-12-14 Derives peptidiques,procede pour leur preparation et leur application dans des compositions a usage therapeutique LU80654A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB5223777 1977-12-15
GB1384578 1978-04-08

Publications (1)

Publication Number Publication Date
LU80654A1 true LU80654A1 (fr) 1980-07-21

Family

ID=26250049

Family Applications (1)

Application Number Title Priority Date Filing Date
LU80654A LU80654A1 (fr) 1977-12-15 1978-12-14 Derives peptidiques,procede pour leur preparation et leur application dans des compositions a usage therapeutique

Country Status (25)

Country Link
US (1) US4178371A (fr)
JP (1) JPS5490142A (fr)
AT (1) AT363198B (fr)
AU (1) AU523732B2 (fr)
CA (1) CA1145330A (fr)
CH (1) CH638177A5 (fr)
CS (1) CS210679B2 (fr)
DD (1) DD140562A5 (fr)
DE (1) DE2854105A1 (fr)
DK (1) DK540678A (fr)
ES (1) ES475997A1 (fr)
FI (1) FI783751A (fr)
FR (1) FR2411829A1 (fr)
GR (1) GR72716B (fr)
IE (1) IE47764B1 (fr)
IL (1) IL56181A (fr)
IT (1) IT7869853A0 (fr)
LU (1) LU80654A1 (fr)
NL (1) NL7812166A (fr)
NZ (1) NZ189047A (fr)
PL (1) PL114981B1 (fr)
PT (1) PT68900A (fr)
SE (1) SE7812720L (fr)
SU (1) SU793386A3 (fr)
ZA (1) ZA786966B (fr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4259234A (en) * 1976-09-27 1981-03-31 Eli Lilly And Company Analgesic compounds
US4322342A (en) * 1977-06-20 1982-03-30 Eli Lilly And Company Analgesic compounds
US4254024A (en) * 1979-10-16 1981-03-03 Pennwalt Corporation Tetrapeptides and derivatives having opiate activity
JPS5692846A (en) * 1979-12-27 1981-07-27 Takeda Chem Ind Ltd Tetrapeptide derivative and its preparation
HU181013B (en) * 1980-01-25 1983-05-30 Gyogyszerkutato Intezet Process for preparing new enkephalin analogues
WO1982000640A1 (fr) * 1980-08-18 1982-03-04 Akita T Derives de tripeptides alkylamide
US4316892A (en) * 1980-11-03 1982-02-23 G. D. Searle & Co. 2,6-C-Dimethyltyrosine1 -D-amino acid2 -ε-amino caproic and γ aminobutyric acid5 derivatives of methionine enkephalin
ATE16495T1 (de) * 1981-06-22 1985-11-15 Ici Plc Peptide und pseudopeptide, die zwei substituenten am n-terminus aufweisen.
US4450155A (en) * 1981-07-24 1984-05-22 Sterling Drug Inc. Analgesic dipeptide amides and method of use and compositions thereof
US4454120A (en) * 1981-07-24 1984-06-12 Sterling Drug Inc. Analgesic dipeptide amides and method of use and compositions thereof
US4533657A (en) * 1981-07-24 1985-08-06 Sterling Drug Inc. Analgesic dipeptide amides and method of use and composition thereof
US4658013A (en) * 1981-07-28 1987-04-14 Sterling Drug Inc. Analgesic and/or opiate antagonist tripeptide amides and processes for preparation and compositions thereof
US4407746A (en) * 1981-12-14 1983-10-04 G. D. Searle & Co. Cyclohexyl and phenyl substituted enkephalins
JPS58146541A (ja) * 1982-02-05 1983-09-01 ザ・ウエルカム・フアウンデ−シヨン・リミテツド ペプチド化合物
US4430327A (en) 1982-05-18 1984-02-07 Eli Lilly And Company Method for treating pregnant females for pain and anxiety
GB8314646D0 (en) * 1983-05-26 1983-06-29 Wellcome Found Pharmaceutical amides
US4603121A (en) * 1983-10-06 1986-07-29 G. D. Searle & Co. Enkephalin analogs
US4495178A (en) * 1983-10-06 1985-01-22 G. D. Searle & Co. Enkephalin analogs
CA2215211A1 (fr) * 1995-03-31 1996-10-03 Takeda Chemical Industries, Ltd. Inhibiteur de la protease de cysteine
FR2788518B1 (fr) * 1999-01-14 2001-03-02 Centre Nat Rech Scient Nouveaux carbamates actives stables, leur procede de preparation et leur utilisation pour la preparation d'urees
US20080033167A1 (en) * 2005-12-29 2008-02-07 Gilles Guichard Compositions and methods for synthesizing heterocyclic therapeutic compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2702711A1 (de) * 1976-02-02 1977-08-04 Sandoz Ag Neue organische verbindungen, ihre herstellung und verwendung
NZ183712A (en) * 1976-04-08 1979-10-25 Ici Ltd Polypeptide analogues of enkephalins, and pharmaceutical compositions

Also Published As

Publication number Publication date
GR72716B (fr) 1983-12-01
CS210679B2 (en) 1982-01-29
SU793386A3 (ru) 1980-12-30
FR2411829A1 (fr) 1979-07-13
IL56181A0 (en) 1979-03-12
ZA786966B (en) 1980-11-26
CH638177A5 (fr) 1983-09-15
AU523732B2 (en) 1982-08-12
FI783751A (fi) 1979-06-16
ES475997A1 (es) 1979-11-01
PL211703A1 (pl) 1979-08-13
SE7812720L (sv) 1979-06-16
AU4219978A (en) 1979-06-21
DK540678A (da) 1979-07-06
ATA899878A (de) 1980-12-15
AT363198B (de) 1981-07-10
IT7869853A0 (it) 1978-12-14
IE47764B1 (en) 1984-06-13
US4178371A (en) 1979-12-11
NL7812166A (nl) 1979-06-19
IE782475L (en) 1979-06-15
IL56181A (en) 1982-05-31
DD140562A5 (de) 1980-03-12
DE2854105A1 (de) 1979-06-21
PL114981B1 (en) 1981-03-31
PT68900A (en) 1979-01-01
NZ189047A (en) 1981-12-15
JPS5490142A (en) 1979-07-17
FR2411829B1 (fr) 1983-11-18
CA1145330A (fr) 1983-04-26

Similar Documents

Publication Publication Date Title
LU80654A1 (fr) Derives peptidiques,procede pour leur preparation et leur application dans des compositions a usage therapeutique
LU80081A1 (fr) Nouvelles hydroxymethyl-5 oxazolidinones-2,leur procede de preparation et leur application therapeutique
ZA786185B (en) Improvements in and relating to pharmaceutical preparations in solid unit dosage form
BE878723A (fr) Derives de 4-anilinoquinazoline, leur procede de preparation et leur application en therapeutique
BE864112A (fr) Derives d'acide benzoique, leur procede de preparation et leur application en therapeutique
BE858520A (fr) Derives de thiazolidine leur procede de preparation leur application en therapeutique
BE854268A (fr) Pyrrolidones, leur procede de preparation et leur application therapeutique
BE851893A (fr) Nouvelles aryl-3 oxazolidinones-2, leur procede de preparation et leur application en therapeutique
LU80078A1 (fr) Procede de preparation de pyrazoles substitues en position 4 et leur utilisation therapeutique
MC1243A1 (fr) Derives peptidiques,procede pour leur preparation et leur application dans des preparations pharmaceutiques
BE864312A (fr) Nouveaux derives de la pyrrolidine, leur procede de preparation et leur application en therapeutique
IL55650A (en) Analgesic tetrapeptide amides,process for their preparation and pharmaceutical compositions comprising them
DE2860858D1 (en) Indolacetoxyacetylaminoacid derivatives, process for their preparation and their use in drugs
JPS5390297A (en) Novel imidazoquinoline salts thereof process for preparing same and pharmaceutical composition
ZA785628B (en) New imidazobenzoxazines and their salts,process for their preparation and pharmaceutical compositions
BE869605A (fr) Nouveaux derives de la diphenoxy-1,3 propanone-2, procede pour leur preparation et leur utilisation dans des compositions pharmaceutiques
FR2349587A1 (fr) 1,3-dihydro-heteroarylspiro(isobenzofurannes), leur procede de preparation et leur application therapeutique
BE866676A (fr) Derives de bisamidine, leur procede de preparation et leur application therapeutique
FR2351965A1 (fr) Benzenesulfonylurees, leur procede de preparation et leur application therapeutique
PT68267A (fr) Procede de preparation de derives d'oxadiazole-1,2,4 et leur application en therapeutique
BE863402A (fr) Azacycloalcanes, azacycloalcenes et derives de ceux-ci, leur procede de preparation et leur application en therapeutique
BE870687A (fr) Nouvelles monoalkylanilines substituees en position 4 utiles comme medicaments et procedes pour leur preparation
DE2860469D1 (en) 4"-ureido-oleandomycin derivatives, process for their preparation and their use in pharmaceutical compositions
DE2860659D1 (en) 1,4-dihydropyridazines, process for their preparation and their use in pharmaceuticals
DE2860726D1 (en) Antibacterially active amides, process for their preparation and pharmaceutical compositions containing said amides