LU79970A1 - Procede de preparation de derives de 1-phenyl-1-propanol - Google Patents

Procede de preparation de derives de 1-phenyl-1-propanol Download PDF

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Publication number
LU79970A1
LU79970A1 LU79970A LU79970A LU79970A1 LU 79970 A1 LU79970 A1 LU 79970A1 LU 79970 A LU79970 A LU 79970A LU 79970 A LU79970 A LU 79970A LU 79970 A1 LU79970 A1 LU 79970A1
Authority
LU
Luxembourg
Prior art keywords
formula
group
radical
derivatives
action
Prior art date
Application number
LU79970A
Other languages
English (en)
French (fr)
Inventor
G Lambelin
C Gillet
J Roba
R Roncucci
Original Assignee
Continental Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Continental Pharma filed Critical Continental Pharma
Priority to LU79970A priority Critical patent/LU79970A1/fr
Priority to FI792123A priority patent/FI792123A7/fi
Priority to DE19792927789 priority patent/DE2927789A1/de
Priority to SE7905992A priority patent/SE446631B/sv
Priority to CA331,500A priority patent/CA1127164A/en
Priority to AT0483579A priority patent/AT368491B/de
Priority to ES482432A priority patent/ES482432A1/es
Priority to NO792329A priority patent/NO148452C/no
Priority to DK293779A priority patent/DK293779A/da
Priority to GB7924292A priority patent/GB2025417B/en
Priority to FR7918156A priority patent/FR2438649A1/fr
Priority to CH651479A priority patent/CH644355A5/fr
Priority to PT69909A priority patent/PT69909A/pt
Priority to IT24357/79A priority patent/IT1122180B/it
Priority to ZA00793554A priority patent/ZA793554B/xx
Priority to NL7905507A priority patent/NL7905507A/nl
Priority to BE0/196294A priority patent/BE877694A/xx
Priority to JP54088352A priority patent/JPS5943943B2/ja
Priority to FR8003187A priority patent/FR2443457A1/fr
Publication of LU79970A1 publication Critical patent/LU79970A1/fr
Priority to AT0443181A priority patent/AT371107B/de
Priority to AT0443081A priority patent/AT371106B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
    • C07D207/27—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/26—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C317/32—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/10—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C323/18—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
    • C07C323/19—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton with singly-bound oxygen atoms bound to acyclic carbon atoms of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/31—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
    • C07C323/32—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton having at least one of the nitrogen atoms bound to an acyclic carbon atom of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/34—Compounds containing oxirane rings with hydrocarbon radicals, substituted by sulphur, selenium or tellurium atoms

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
LU79970A 1978-07-13 1978-07-13 Procede de preparation de derives de 1-phenyl-1-propanol LU79970A1 (fr)

Priority Applications (21)

Application Number Priority Date Filing Date Title
LU79970A LU79970A1 (fr) 1978-07-13 1978-07-13 Procede de preparation de derives de 1-phenyl-1-propanol
FI792123A FI792123A7 (fi) 1978-07-13 1979-07-05 1-fenyyli-1-propanolin johdannaisia.
DE19792927789 DE2927789A1 (de) 1978-07-13 1979-07-10 1-phenyl-1-propanol-derivate
SE7905992A SE446631B (sv) 1978-07-13 1979-07-10 1-fenyl-1-propanolderivat och sett att framstella detta
CA331,500A CA1127164A (en) 1978-07-13 1979-07-10 Derivatives of 1-phenyl-1-propanol
AT0483579A AT368491B (de) 1978-07-13 1979-07-11 Verfahren zum herstellen von neuen substituierten 1-phenyl-2-aminopropanolen sowie von deren ersternund saeureadditonssalzen
GB7924292A GB2025417B (en) 1978-07-13 1979-07-12 Derivatives of 1 - phenyl - 1 - propanol
NO792329A NO148452C (no) 1978-07-13 1979-07-12 Analogifremgangsmaate ved fremstilling av terapeutisk aktive 1-fenyl-1-propanol-derivater
DK293779A DK293779A (da) 1978-07-13 1979-07-12 Fremgangsmaade til fremstilling af 1-fenyl-1-propanol-derivater
ES482432A ES482432A1 (es) 1978-07-13 1979-07-12 Procedimiento para la preparacion de derivados de 1-fenil-1-propanol.
FR7918156A FR2438649A1 (fr) 1978-07-13 1979-07-12 Derives de 1-phenyl-1-propanol, leur preparation et leurs utilisations therapeutiques notamment comme antihypertenseurs, vasodilatateurs peripheriques et antithrombiques
CH651479A CH644355A5 (fr) 1978-07-13 1979-07-12 Derives de 1-phenyl-1-propanol.
PT69909A PT69909A (fr) 1978-07-13 1979-07-12 Procede pour la preparation de derives de 1-phenyl-1-propanol
IT24357/79A IT1122180B (it) 1978-07-13 1979-07-13 Derivati di 1-fenil-1-propanolo
ZA00793554A ZA793554B (en) 1978-07-13 1979-07-13 Derivatives of 1-phenyl-1-propanol
NL7905507A NL7905507A (nl) 1978-07-13 1979-07-13 1-fenylpropanol-1-derivaten, werkwijzen ter bereiding ervan, alsmede farmaceutische preparaten, die de derivaten bevatten.
BE0/196294A BE877694A (fr) 1978-07-13 1979-07-13 Derives de 1-phenyl-1-propanol.
JP54088352A JPS5943943B2 (ja) 1978-07-13 1979-07-13 １↓−フェニル↓−プロパノ−ル誘導体およびその製造方法
FR8003187A FR2443457A1 (fr) 1978-07-13 1980-02-13 Derives de 1-phenyl-2-amino-1-propanol, leur procede de preparation et leur utilisation comme medicaments
AT0443181A AT371107B (de) 1978-07-13 1981-10-15 Verfahren zur herstellung von neuen 1-(4'mercaptophenyl)-2-aminopropanolen und deren saeureadditionssalzen
AT0443081A AT371106B (de) 1978-07-13 1981-10-15 Verfahren zur herstellung von neuen substituierten 1-phenyl-2-aminopropanolen sowie deren estern undsaeureadditionssalzen

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
LU79970 1978-07-13
LU79970A LU79970A1 (fr) 1978-07-13 1978-07-13 Procede de preparation de derives de 1-phenyl-1-propanol

Publications (1)

Publication Number Publication Date
LU79970A1 true LU79970A1 (fr) 1980-02-14

Family

ID=19728955

Family Applications (1)

Application Number Title Priority Date Filing Date
LU79970A LU79970A1 (fr) 1978-07-13 1978-07-13 Procede de preparation de derives de 1-phenyl-1-propanol

Country Status (18)

Country Link
JP (1) JPS5943943B2 (de)
AT (1) AT368491B (de)
BE (1) BE877694A (de)
CA (1) CA1127164A (de)
CH (1) CH644355A5 (de)
DE (1) DE2927789A1 (de)
DK (1) DK293779A (de)
ES (1) ES482432A1 (de)
FI (1) FI792123A7 (de)
FR (2) FR2438649A1 (de)
GB (1) GB2025417B (de)
IT (1) IT1122180B (de)
LU (1) LU79970A1 (de)
NL (1) NL7905507A (de)
NO (1) NO148452C (de)
PT (1) PT69909A (de)
SE (1) SE446631B (de)
ZA (1) ZA793554B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3128117A1 (de) * 1980-07-29 1982-03-11 Yamanouchi Pharmaceutical Co., Ltd., Tokyo Neue phenyl-aethylaminderivate, verfahren zu ihrer herstellung
LU83039A1 (fr) * 1980-12-24 1982-07-07 Continental Pharma Procedes de synthese du 1-(4 isopropylthiophenyl)-2-n octylaminopropanol
DE3262620D1 (en) * 1981-05-27 1985-04-25 Maggioni Farma 4-alkyl-thiophenyl-ethanolamines, having an activity on the cerebral circulation, the blood platelet-aggregation and the lipemia
FR2537132B1 (fr) * 1982-12-06 1987-01-09 Lafon Labor Nouveaux derives soufres de 2-amino-1-phenyl-1-ethanol, utilisation en therapeutique et procede de preparation
US4582918A (en) * 1984-09-19 1986-04-15 Schering Corporation Preparation of intermediates for (threo)-1-aryl-2-acylamido-3-fluoro-1-propanols
BE1014245A4 (fr) * 2001-04-03 2003-07-01 Malak Jean Composes chimiques derives de l'octopamine et leurs utilisations en tant qu'agonistes beta 3-adrenergiques.
WO2006043710A1 (ja) * 2004-10-19 2006-04-27 Reverse Proteomics Research Institute Co., Ltd. 創薬標的タンパク質及び標的遺伝子、並びにスクリーニング方法
IL187245A0 (en) * 2007-11-08 2008-12-29 Hadasit Med Res Service Synthetic sphingolipid analogs

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1366096A (fr) * 1962-05-28 1964-07-10 Castrol Ltd Copolymères pour utilisation dans les compositions d'huiles lubrifiantes et leurs produits intermédiaires
FR1480780A (fr) * 1965-05-24 1967-05-12 Shell Int Research Production de pyrrolidone

Also Published As

Publication number Publication date
ZA793554B (en) 1980-06-25
ATA483579A (de) 1982-02-15
JPS5533467A (en) 1980-03-08
FI792123A7 (fi) 1981-01-01
GB2025417A (en) 1980-01-23
DE2927789A1 (de) 1980-01-24
JPS5943943B2 (ja) 1984-10-25
SE446631B (sv) 1986-09-29
NO792329L (no) 1980-01-15
PT69909A (fr) 1979-08-01
IT1122180B (it) 1986-04-23
FR2443457B1 (de) 1983-09-23
CA1127164A (en) 1982-07-06
ES482432A1 (es) 1980-04-01
NO148452B (no) 1983-07-04
FR2438649B1 (de) 1983-03-25
AT368491B (de) 1982-10-11
NO148452C (no) 1983-10-12
GB2025417B (en) 1983-03-02
CH644355A5 (fr) 1984-07-31
FR2443457A1 (fr) 1980-07-04
BE877694A (fr) 1979-11-05
NL7905507A (nl) 1980-01-15
FR2438649A1 (fr) 1980-05-09
IT7924357A0 (it) 1979-07-13
DK293779A (da) 1980-01-14
SE7905992L (sv) 1980-01-14

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Free format text: 860109 CONTINENTAL PHARMA INC. BRUXELLES