LU77306A1 - - Google Patents

Info

Publication number
LU77306A1
LU77306A1 LU77306A LU77306A LU77306A1 LU 77306 A1 LU77306 A1 LU 77306A1 LU 77306 A LU77306 A LU 77306A LU 77306 A LU77306 A LU 77306A LU 77306 A1 LU77306 A1 LU 77306A1
Authority
LU
Luxembourg
Application number
LU77306A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Priority to LU77306A priority Critical patent/LU77306A1/xx
Priority to CH439078A priority patent/CH646173A5/de
Priority to US05/902,639 priority patent/US4331676A/en
Priority to DE19782819655 priority patent/DE2819655A1/de
Priority to FR7813535A priority patent/FR2405949A1/fr
Priority to SE7805217A priority patent/SE443980B/sv
Priority to ES469568A priority patent/ES469568A1/es
Priority to GB2015/81A priority patent/GB1604752A/en
Priority to IT4923178A priority patent/IT1156725B/it
Priority to DK200578A priority patent/DK200578A/da
Priority to GB18282/78A priority patent/GB1604751A/en
Priority to GB2016/81A priority patent/GB1604753A/en
Priority to GB2017/81A priority patent/GB1604754A/en
Priority to AU35884/78A priority patent/AU527917B2/en
Priority to JP5415778A priority patent/JPS53137951A/ja
Priority to BE187509A priority patent/BE866845A/xx
Priority to NL7804974A priority patent/NL7804974A/xx
Priority to FR7900171A priority patent/FR2405946A1/fr
Priority to FR7900172A priority patent/FR2411179A1/fr
Priority to FR7900167A priority patent/FR2405955A1/fr
Priority to FR7900173A priority patent/FR2422637A1/fr
Priority to FR7900168A priority patent/FR2405934A1/fr
Priority to FR7900170A priority patent/FR2405945A1/fr
Priority to FR7900169A priority patent/FR2405950A1/fr
Publication of LU77306A1 publication Critical patent/LU77306A1/xx
Priority to US06/214,316 priority patent/US4447360A/en
Priority to US06/353,288 priority patent/US4500457A/en
Priority to DK388582A priority patent/DK388582A/da
Priority to DK388482A priority patent/DK388482A/da
Priority to DK398082A priority patent/DK398082A/da
Priority to US06/423,359 priority patent/US4524028A/en
Priority to US06/423,350 priority patent/US4518533A/en
Priority to US06/423,351 priority patent/US4515717A/en
Priority to SE8305299A priority patent/SE8305299D0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/568—Four-membered rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
LU77306A 1977-05-09 1977-05-09 LU77306A1 (pl)

Priority Applications (33)

Application Number Priority Date Filing Date Title
LU77306A LU77306A1 (pl) 1977-05-09 1977-05-09
CH439078A CH646173A5 (de) 1977-05-09 1978-04-24 Thia-azaverbindungen mit beta-lactamring.
US05/902,639 US4331676A (en) 1977-05-09 1978-05-04 Thia-aza compounds with a β-lactam ring
DE19782819655 DE2819655A1 (de) 1977-05-09 1978-05-05 Thia-azaverbindungen mit beta- lactamring
FR7813535A FR2405949A1 (fr) 1977-05-09 1978-05-08 Composes thia-aza a noyau b-lactame utiles notamment comme medicaments
SE7805217A SE443980B (sv) 1977-05-09 1978-05-08 Forfarande for framstellning av 2-penem-3-karboxylsyraforeningar
ES469568A ES469568A1 (es) 1977-05-09 1978-05-08 Procedimiento para la obtencion de compuestos de acido 2-pe-nem-3-carboxilicos
GB2015/81A GB1604752A (en) 1977-05-09 1978-05-08 4-thio-2-oxoazetidine derivatives
IT4923178A IT1156725B (it) 1977-05-09 1978-05-08 Tia-azacomposti con anello betalattamico e procedimento per produrli
DK200578A DK200578A (da) 1977-05-09 1978-05-08 Thia-azaforbindelser med beta-lactamring fremgangsmaade til fremstilling deraf samt anvendelsen deraf
GB18282/78A GB1604751A (en) 1977-05-09 1978-05-08 2-substituted and 2-unsubstituted 2-penem-3-carboxylic acid derivatives
GB2016/81A GB1604753A (en) 1977-05-09 1978-05-08 2-(2-oxo-1-azetidinyl)-acetic acid derivatives
GB2017/81A GB1604754A (en) 1977-05-09 1978-05-08 2-(2-oxo-1-azetidinyl)-2-phpshonio-or-phosphonoacetic acid derivatives
AU35884/78A AU527917B2 (en) 1977-05-09 1978-05-08 2-pemer compounds
BE187509A BE866845A (fr) 1977-05-09 1978-05-09 Composes thia-aza a noyau beta-lactame utiles notamment comme medicaments
JP5415778A JPS53137951A (en) 1977-05-09 1978-05-09 Thiaaaza compound having betaalactum ring
NL7804974A NL7804974A (nl) 1977-05-09 1978-05-09 2-penem-3-carbonzuurverbindingen.
FR7900170A FR2405945A1 (fr) 1977-05-09 1979-01-04 Nouveaux derives de l'acide 4 dithio 3-methylenebutyrique et procede pour leur preparation
FR7900169A FR2405950A1 (fr) 1977-05-09 1979-01-04 Nouveaux 1 oxydes de l'acide penicillanique utiles dans la synthese de medicaments
FR7900172A FR2411179A1 (fr) 1977-05-09 1979-01-04 Nouveaux derives de l'acide 2-(4-thio-2-oxoazetidine-1-yl)-3-methyl-crotonique et procedes pour leur preparation
FR7900167A FR2405955A1 (fr) 1977-05-09 1979-01-04 Nouveaux ylides utiles dans la synthese de medicaments
FR7900173A FR2422637A1 (fr) 1977-05-09 1979-01-04 Nouveaux derives de l'acide 2(4-thio-2-oxo-azetidin-1-yl)-3-methylene-butyrique et procede de preparation
FR7900168A FR2405934A1 (fr) 1977-05-09 1979-01-04 Nouvelles 4-thio-2-oxo azetidines utiles dans la synthese de medicaments
FR7900171A FR2405946A1 (fr) 1977-05-09 1979-01-04 Nouveaux derives de l'acide 3-methyl-crotonique et procede pour leur preparation
US06/214,316 US4447360A (en) 1977-05-09 1980-12-08 Intermediates for thia-aza compounds with a β-lactam ring
US06/353,288 US4500457A (en) 1977-05-09 1982-03-01 Process for preparing thia-aza compounds with a beta-lactam ring
DK388582A DK388582A (da) 1977-05-09 1982-08-31 2-(-oxo-1-azetidinyl)-eddikesyre-forbindelser
DK388482A DK388482A (da) 1977-05-09 1982-08-31 4-thio-2-oxoazetidinon-forbindelser
DK398082A DK398082A (da) 1977-05-09 1982-09-06 Ylid-forbindelser
US06/423,359 US4524028A (en) 1977-05-09 1982-09-24 Monocyclic intermediates for thia-aza compounds with a β-lactam ring
US06/423,350 US4518533A (en) 1977-05-09 1982-09-24 Azetidinone-4-disulfides as intermediates for thia-aza compounds with a beta-lactam ring
US06/423,351 US4515717A (en) 1977-05-09 1982-09-24 Thia-aza compounds with a β-lactam ring
SE8305299A SE8305299D0 (sv) 1977-05-09 1983-09-29 Tiaazaforeningar med -laktamer

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
LU77306A LU77306A1 (pl) 1977-05-09 1977-05-09

Publications (1)

Publication Number Publication Date
LU77306A1 true LU77306A1 (pl) 1979-01-18

Family

ID=19728568

Family Applications (1)

Application Number Title Priority Date Filing Date
LU77306A LU77306A1 (pl) 1977-05-09 1977-05-09

Country Status (13)

Country Link
US (5) US4331676A (pl)
JP (1) JPS53137951A (pl)
AU (1) AU527917B2 (pl)
BE (1) BE866845A (pl)
CH (1) CH646173A5 (pl)
DE (1) DE2819655A1 (pl)
DK (1) DK200578A (pl)
ES (1) ES469568A1 (pl)
FR (8) FR2405949A1 (pl)
GB (4) GB1604752A (pl)
LU (1) LU77306A1 (pl)
NL (1) NL7804974A (pl)
SE (2) SE443980B (pl)

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5055573A (en) * 1976-11-19 1991-10-08 Merck & Co., Inc. Process for preparing 1-carba-2-penem-3-carboxylic acid
US4234579A (en) * 1977-06-07 1980-11-18 Pfizer Inc. Penicillanic acid 1,1-dioxides as β-lactamase inhibitors
IN149747B (pl) * 1977-06-07 1982-04-03 Pfizer
US4168314A (en) * 1977-11-17 1979-09-18 Merck & Co., Inc. 6-(1'-Hydroxyethyl)-2-aminoethylthio-pen-2-em-3-carboxylic acid
JPS54117459A (en) * 1978-01-20 1979-09-12 Glaxo Group Ltd Novel lactam compound
EP0042026B1 (de) * 1978-02-02 1986-01-08 Ciba-Geigy Ag 3,4-Disubstituierte Azetidin-2-onverbindungen und Verfahren zu ihrer Herstellung
JPS54145692A (en) * 1978-02-16 1979-11-14 Glaxo Group Ltd Betaalactam compound
EP0010358A1 (en) * 1978-09-20 1980-04-30 Glaxo Group Limited Beta-lactam compounds, processes for their preparation, compositions containing them, intermediates of use in their preparation and methods for the production thereof
US4290948A (en) 1978-11-22 1981-09-22 Beecham Group Limited Process for their preparation of β-lactam antibacterial agents
US4331677A (en) * 1978-11-24 1982-05-25 Farmitalia Carlo Erba S.P.A. 7-Oxo-4-1-aza-bicyclo-[3,2,0]-heptane derivatives
US4272437A (en) 1978-12-18 1981-06-09 Bristol-Myers Company Antibacterial agents, and 4-thio azetidinone intermediates
US4282150A (en) 1978-12-18 1981-08-04 Bristol-Myers Company 2,6-Disubstituted penem compounds
JPS5625110A (en) * 1978-12-18 1981-03-10 Bristol Myers Co Antibacterial
EP0013067A1 (en) * 1978-12-22 1980-07-09 Beecham Group Plc Bicyclic beta-lactam antibacterial agents, their use in pharmaceutical compositions, processes for their preparation and intermediates for use in such processes
IL59081A0 (en) * 1979-01-10 1980-05-30 Schering Corp 2-penem compounds and a method for preparing them
ATE3041T1 (de) * 1979-01-10 1983-04-15 Schering Corporation 2-penem-verbindungen, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen.
AT368506B (de) * 1979-02-24 1982-10-25 Erba Farmitalia Verfahren zur herstellung von neuen penemcarbonsaeuren und deren salzen
US4714761A (en) * 1979-03-05 1987-12-22 Pfizer Inc. 6,6-dihalopenicillanic acid 1,1-dioxides and process
US4420426A (en) 1979-03-05 1983-12-13 Pfizer Inc. 6-Alpha-halopenicillanic acid 1,1-dioxides
US4269771A (en) * 1979-04-06 1981-05-26 Farmitalia Carlo Erba Total synthesis of 7-oxo-4-thia-1-azabicyclo-[3,2,0]-heptane-2-carboxyl derivatives useful as β-lactamase inhibitors and antibacterial agents
US4683226A (en) * 1979-08-01 1987-07-28 Schering Corporation 6-hydroxyalkyl-2-(substituted-thio)penem-3-carboxylic acids
US4374065A (en) 1979-09-21 1983-02-15 Bristol-Myers Company Antibacterial agents of the β-lactam type
US4406834A (en) 1979-09-21 1983-09-27 Bristol-Myers Company 2,6 Disubstituted penems and intermediates therefor
US4378314A (en) 1979-09-21 1983-03-29 Bristol Myers Company Antibacterial agents and metal containing azetidinone intermediates therefore
DE3069524D1 (en) * 1979-12-20 1984-11-29 Hoechst Uk Ltd Penem derivatives
US4482565A (en) * 1980-02-22 1984-11-13 Farmitalia Carlo Erba S.P.A. β-Lactam-containing antibacterial agents and β-lactamase inhibitors
JPS56142283A (en) * 1980-03-17 1981-11-06 Sankyo Co Ltd Penem-3-carboxylic acid derivative and its preparation
JPS56142282A (en) * 1980-03-10 1981-11-06 Sankyo Co Ltd Penem-3-carboxylic acid derivative and its preparation
EP0176064A1 (en) * 1980-11-06 1986-04-02 Hoechst Uk Limited Intermediates for the production of 7-oxo-4-thia-1-aza[3,2,0]heptane and 7-oxo-4-thia-1-aza[3,2,0]hept-2-ene derivatives
DE3274982D1 (en) * 1981-07-08 1987-02-12 Hoechst Uk Ltd Antibacterial penem derivatives
ES8305366A1 (es) * 1981-07-08 1983-04-01 Hoechst Uk Ltd "procedimiento para la preparacion de derivados de penem".
JPS58116487A (ja) * 1981-12-28 1983-07-11 Sumitomo Chem Co Ltd 新規なβ−ラクタム化合物及びその製造法
JPS5835190A (ja) * 1981-08-25 1983-03-01 Sankyo Co Ltd ペネム−３−カルボン酸誘導体
JPS5946289A (ja) * 1982-09-08 1984-03-15 Sumitomo Chem Co Ltd 新規なβ−ラクタム化合物及びその製造法
US4595539A (en) * 1983-06-10 1986-06-17 Pfizer Inc. Preparation of penem derivatives and azetidinone intermediates
US4725678A (en) * 1983-06-10 1988-02-16 Pfizer Inc. Azetidinone intermediates for the preparation of penem derivatives
US5229381A (en) * 1983-12-01 1993-07-20 Merck & Co., Inc. Substituted azetidinones as anti-inflammatory and antidegenerative agents
US4680391A (en) * 1983-12-01 1987-07-14 Merck & Co., Inc. Substituted azetidinones as anti-inflammatory and antidegenerative agents
US5229510A (en) * 1983-12-01 1993-07-20 Merck & Co., Inc. β-lactams useful in determining the amount of elastase in a clinical sample
JPS60243064A (ja) * 1984-05-17 1985-12-03 Taiho Yakuhin Kogyo Kk アゼチジノンジスルフイド誘導体
EP0379281A3 (en) * 1989-01-19 1991-03-20 Cosmopolitan Textile Company Limited Web inspecting method and apparatus
US5104862A (en) * 1991-03-20 1992-04-14 Merck & Co., Inc. Bethalactam elastase inhibitors containing phosphorous acid derivatives at the 4-position of the 2-azetidinone
US5100880A (en) * 1991-03-20 1992-03-31 Merck & Co., Inc. Novel betalactam elastase inhibitors containing phosphorous acid derivatives at the 4-position of the 2-azetidinone
US5348953A (en) * 1991-06-25 1994-09-20 Merck & Co., Inc. Substituted azetidinones as anti-inflammatory and antidegenerative agents
WO1994010143A1 (en) * 1992-10-27 1994-05-11 Merck & Co., Inc. New substituted azetidinones as anti-inflammatory and antidegenerative agents
US5591737A (en) * 1992-12-17 1997-01-07 Merck & Co., Inc. Substituted azetidinones as anti-inflammatory and antidegenerative agents
US5747485A (en) * 1995-04-13 1998-05-05 Merck & Co., Inc. Substituted azetidiones as anti-inflammatory and antidegenerative agents
AU2003274518A1 (en) * 2002-11-01 2004-05-25 Orchid Chemicals And Pharmaceuticals Ltd A process for the preparation of benzyl 2-oxo-4- (heteroaryl) dithio-alpha-isoprenyl-1- azetidineazetate derivatives
EP2209474A4 (en) 2007-10-09 2013-07-24 Sopharmia Inc BROAD SPECTRUM BETA-LACTAMASE INHIBITORS
EP2852569B1 (en) * 2012-05-23 2020-10-14 Cellixbio Private Limited Compositions and methods for the treatment of multiple sclerosis
EP3790843A1 (de) * 2018-05-07 2021-03-17 Covestro Intellectual Property GmbH & Co. KG Speichermedium und verfahren für die abtrennung, die speicherung und den transport von chlor aus chlor enthaltenden gasen
CN114720591B (zh) * 2022-03-22 2022-12-30 北京安胜瑞力科技有限公司 一种工业废水中dmac的定量分析方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE648188A (pl) 1963-05-29 1964-09-16
BE755940A (fr) * 1969-09-09 1971-03-09 Hoechst Ag Azetidinones-2 portant des substituants en position 4 et leur preparation
GB1368074A (en) * 1971-02-04 1974-09-25 Beecham Group Ltd Substituted beta-lactams and their preparation
DE2265798C2 (de) * 1971-06-24 1985-09-26 Fujisawa Pharmaceutical Co., Ltd., Osaka Verfahren zur Herstellung von Oxoazetidin-Derivaten
JPS4854056A (pl) * 1971-11-12 1973-07-30
US4070477A (en) * 1975-12-08 1978-01-24 Ciba-Geigy Corporation 2-Penem compounds
IN149747B (pl) * 1977-06-07 1982-04-03 Pfizer
EP0000636A1 (en) * 1977-07-13 1979-02-07 Glaxo Group Limited Penem compounds, processes for their preparation, their use in pharmaceutical compositions and azetidinones used in their preparation
GB2005246A (en) * 1977-07-13 1979-04-19 Glaxo Group Ltd beta -Lactam compounds and processes for their preparation
US4155912A (en) * 1977-12-14 1979-05-22 Bristol-Myers Company 2-Methylpenem-3-carboxylic acid antibiotics
US4169833A (en) * 1977-12-14 1979-10-02 Bristol-Myers Company Novel phosphorane intermediates for use in preparing penem antibiotics
US4182711A (en) * 1978-04-27 1980-01-08 Bristol-Myers Company Antibacterial agents of the β-lactam type
US4192801A (en) * 1978-04-27 1980-03-11 Bristol-Myers Company Novel phosphorane intermediates for use in preparing penem antibiotics
US4282150A (en) * 1978-12-18 1981-08-04 Bristol-Myers Company 2,6-Disubstituted penem compounds
US4272437A (en) * 1978-12-18 1981-06-09 Bristol-Myers Company Antibacterial agents, and 4-thio azetidinone intermediates

Also Published As

Publication number Publication date
FR2405955A1 (fr) 1979-05-11
JPS53137951A (en) 1978-12-01
FR2405946A1 (fr) 1979-05-11
FR2405949A1 (fr) 1979-05-11
DK200578A (da) 1978-11-10
US4447360A (en) 1984-05-08
US4515717A (en) 1985-05-07
US4524028A (en) 1985-06-18
FR2411179B1 (pl) 1982-04-23
DE2819655A1 (de) 1978-11-23
FR2411179A1 (fr) 1979-07-06
FR2405949B1 (pl) 1980-10-24
FR2422637A1 (fr) 1979-11-09
GB1604752A (en) 1981-12-16
FR2405945B1 (pl) 1982-04-09
US4331676A (en) 1982-05-25
FR2405934A1 (fr) 1979-05-11
FR2422637B1 (pl) 1982-04-23
CH646173A5 (de) 1984-11-15
FR2405934B1 (pl) 1980-09-05
BE866845A (fr) 1978-11-09
AU3588478A (en) 1979-11-15
SE8305299L (sv) 1983-09-29
GB1604753A (en) 1981-12-16
FR2405955B1 (pl) 1981-07-31
FR2405950B1 (pl) 1981-07-31
SE443980B (sv) 1986-03-17
SE8305299D0 (sv) 1983-09-29
SE7805217L (sv) 1978-11-10
NL7804974A (nl) 1978-11-13
FR2405946B1 (pl) 1983-09-30
GB1604751A (en) 1981-12-16
FR2405945A1 (fr) 1979-05-11
FR2405950A1 (fr) 1979-05-11
GB1604754A (en) 1981-12-16
US4518533A (en) 1985-05-21
AU527917B2 (en) 1983-03-31
ES469568A1 (es) 1980-01-01

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