NL7804974A - 2-penem-3-carbonzuurverbindingen. - Google Patents

2-penem-3-carbonzuurverbindingen.

Info

Publication number
NL7804974A
NL7804974A NL7804974A NL7804974A NL7804974A NL 7804974 A NL7804974 A NL 7804974A NL 7804974 A NL7804974 A NL 7804974A NL 7804974 A NL7804974 A NL 7804974A NL 7804974 A NL7804974 A NL 7804974A
Authority
NL
Netherlands
Prior art keywords
penem
carbonic acid
acid compounds
compounds
carbonic
Prior art date
Application number
NL7804974A
Other languages
English (en)
Original Assignee
Ciba Geigy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy filed Critical Ciba Geigy
Publication of NL7804974A publication Critical patent/NL7804974A/nl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/568—Four-membered rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NL7804974A 1977-05-09 1978-05-09 2-penem-3-carbonzuurverbindingen. NL7804974A (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
LU77306A LU77306A1 (nl) 1977-05-09 1977-05-09

Publications (1)

Publication Number Publication Date
NL7804974A true NL7804974A (nl) 1978-11-13

Family

ID=19728568

Family Applications (1)

Application Number Title Priority Date Filing Date
NL7804974A NL7804974A (nl) 1977-05-09 1978-05-09 2-penem-3-carbonzuurverbindingen.

Country Status (13)

Country Link
US (5) US4331676A (nl)
JP (1) JPS53137951A (nl)
AU (1) AU527917B2 (nl)
BE (1) BE866845A (nl)
CH (1) CH646173A5 (nl)
DE (1) DE2819655A1 (nl)
DK (1) DK200578A (nl)
ES (1) ES469568A1 (nl)
FR (8) FR2405949A1 (nl)
GB (4) GB1604753A (nl)
LU (1) LU77306A1 (nl)
NL (1) NL7804974A (nl)
SE (2) SE443980B (nl)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0002210A1 (en) * 1977-11-17 1979-06-13 Merck & Co. Inc. 6- and 6,6- disubstituted-2-substituted-pen-2-em-3-carboxylic acids; processes for their preparation and pharmaceutical compositions containing such compounds

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5055573A (en) * 1976-11-19 1991-10-08 Merck & Co., Inc. Process for preparing 1-carba-2-penem-3-carboxylic acid
IN149747B (nl) * 1977-06-07 1982-04-03 Pfizer
US4234579A (en) * 1977-06-07 1980-11-18 Pfizer Inc. Penicillanic acid 1,1-dioxides as β-lactamase inhibitors
JPS54117459A (en) * 1978-01-20 1979-09-12 Glaxo Group Ltd Novel lactam compound
EP0042026B1 (de) * 1978-02-02 1986-01-08 Ciba-Geigy Ag 3,4-Disubstituierte Azetidin-2-onverbindungen und Verfahren zu ihrer Herstellung
JPS54145692A (en) * 1978-02-16 1979-11-14 Glaxo Group Ltd Betaalactam compound
EP0010358A1 (en) * 1978-09-20 1980-04-30 Glaxo Group Limited Beta-lactam compounds, processes for their preparation, compositions containing them, intermediates of use in their preparation and methods for the production thereof
US4290948A (en) 1978-11-22 1981-09-22 Beecham Group Limited Process for their preparation of β-lactam antibacterial agents
US4331677A (en) * 1978-11-24 1982-05-25 Farmitalia Carlo Erba S.P.A. 7-Oxo-4-1-aza-bicyclo-[3,2,0]-heptane derivatives
US4282150A (en) 1978-12-18 1981-08-04 Bristol-Myers Company 2,6-Disubstituted penem compounds
US4272437A (en) 1978-12-18 1981-06-09 Bristol-Myers Company Antibacterial agents, and 4-thio azetidinone intermediates
JPS5625110A (en) * 1978-12-18 1981-03-10 Bristol Myers Co Antibacterial
EP0013067A1 (en) * 1978-12-22 1980-07-09 Beecham Group Plc Bicyclic beta-lactam antibacterial agents, their use in pharmaceutical compositions, processes for their preparation and intermediates for use in such processes
IL59081A0 (en) * 1979-01-10 1980-05-30 Schering Corp 2-penem compounds and a method for preparing them
DE3071497D1 (en) * 1979-01-10 1986-04-17 Schering Corp 2-penem compounds; a method for their preparation and pharmaceutical compositions comprising them
AU535080B2 (en) * 1979-02-24 1984-03-01 Farmitalia Carlo Erba S.R.L. Penicillins
US4420426A (en) 1979-03-05 1983-12-13 Pfizer Inc. 6-Alpha-halopenicillanic acid 1,1-dioxides
US4714761A (en) * 1979-03-05 1987-12-22 Pfizer Inc. 6,6-dihalopenicillanic acid 1,1-dioxides and process
US4269771A (en) * 1979-04-06 1981-05-26 Farmitalia Carlo Erba Total synthesis of 7-oxo-4-thia-1-azabicyclo-[3,2,0]-heptane-2-carboxyl derivatives useful as β-lactamase inhibitors and antibacterial agents
US4683226A (en) * 1979-08-01 1987-07-28 Schering Corporation 6-hydroxyalkyl-2-(substituted-thio)penem-3-carboxylic acids
US4406834A (en) 1979-09-21 1983-09-27 Bristol-Myers Company 2,6 Disubstituted penems and intermediates therefor
US4378314A (en) 1979-09-21 1983-03-29 Bristol Myers Company Antibacterial agents and metal containing azetidinone intermediates therefore
US4374065A (en) 1979-09-21 1983-02-15 Bristol-Myers Company Antibacterial agents of the β-lactam type
EP0031509B1 (en) * 1979-12-20 1984-10-24 Hoechst Uk Limited Penem derivatives
US4482565A (en) * 1980-02-22 1984-11-13 Farmitalia Carlo Erba S.P.A. β-Lactam-containing antibacterial agents and β-lactamase inhibitors
JPS56142282A (en) * 1980-03-10 1981-11-06 Sankyo Co Ltd Penem-3-carboxylic acid derivative and its preparation
JPS56142283A (en) * 1980-03-17 1981-11-06 Sankyo Co Ltd Penem-3-carboxylic acid derivative and its preparation
EP0176064A1 (en) * 1980-11-06 1986-04-02 Hoechst Uk Limited Intermediates for the production of 7-oxo-4-thia-1-aza[3,2,0]heptane and 7-oxo-4-thia-1-aza[3,2,0]hept-2-ene derivatives
ES8305366A1 (es) * 1981-07-08 1983-04-01 Hoechst Uk Ltd "procedimiento para la preparacion de derivados de penem".
DE3274982D1 (en) * 1981-07-08 1987-02-12 Hoechst Uk Ltd Antibacterial penem derivatives
JPS58116487A (ja) * 1981-12-28 1983-07-11 Sumitomo Chem Co Ltd 新規なβ−ラクタム化合物及びその製造法
JPS5835190A (ja) * 1981-08-25 1983-03-01 Sankyo Co Ltd ペネム−３−カルボン酸誘導体
JPS5946289A (ja) * 1982-09-08 1984-03-15 Sumitomo Chem Co Ltd 新規なβ−ラクタム化合物及びその製造法
US4725678A (en) * 1983-06-10 1988-02-16 Pfizer Inc. Azetidinone intermediates for the preparation of penem derivatives
US4595539A (en) * 1983-06-10 1986-06-17 Pfizer Inc. Preparation of penem derivatives and azetidinone intermediates
US5229510A (en) * 1983-12-01 1993-07-20 Merck & Co., Inc. β-lactams useful in determining the amount of elastase in a clinical sample
US4680391A (en) * 1983-12-01 1987-07-14 Merck & Co., Inc. Substituted azetidinones as anti-inflammatory and antidegenerative agents
US5229381A (en) * 1983-12-01 1993-07-20 Merck & Co., Inc. Substituted azetidinones as anti-inflammatory and antidegenerative agents
JPS60243064A (ja) * 1984-05-17 1985-12-03 Taiho Yakuhin Kogyo Kk アゼチジノンジスルフイド誘導体
EP0379281A3 (en) * 1989-01-19 1991-03-20 Cosmopolitan Textile Company Limited Web inspecting method and apparatus
US5100880A (en) * 1991-03-20 1992-03-31 Merck & Co., Inc. Novel betalactam elastase inhibitors containing phosphorous acid derivatives at the 4-position of the 2-azetidinone
US5104862A (en) * 1991-03-20 1992-04-14 Merck & Co., Inc. Bethalactam elastase inhibitors containing phosphorous acid derivatives at the 4-position of the 2-azetidinone
US5348953A (en) * 1991-06-25 1994-09-20 Merck & Co., Inc. Substituted azetidinones as anti-inflammatory and antidegenerative agents
CA2147129A1 (en) * 1992-10-27 1994-05-11 James B. Doherty New substituted azetidinones as anti-inflammatory and antidegenerative agents
US5591737A (en) * 1992-12-17 1997-01-07 Merck & Co., Inc. Substituted azetidinones as anti-inflammatory and antidegenerative agents
US5747485A (en) * 1995-04-13 1998-05-05 Merck & Co., Inc. Substituted azetidiones as anti-inflammatory and antidegenerative agents
WO2004039776A2 (en) * 2002-11-01 2004-05-13 Orchid Chemicals & Pharmaceuticals Ltd A process for the preparation of benzyl 2-oxo-4- (heteroaryl) dithio-alpha-isoprenyl-1- azetidineazetate derivatives
US8883772B2 (en) 2007-10-09 2014-11-11 Sopharmia, Inc. Broad spectrum beta-lactamase inhibitors
EP2852569B1 (en) * 2012-05-23 2020-10-14 Cellixbio Private Limited Compositions and methods for the treatment of multiple sclerosis
US11905177B2 (en) * 2018-05-07 2024-02-20 Covestro Intellectual Property Gmbh & Co. Kg Storage medium and method for separating, storing and transporting chlorine from chlorine-containing gases
CN114720591B (zh) * 2022-03-22 2022-12-30 北京安胜瑞力科技有限公司 一种工业废水中dmac的定量分析方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE648188A (nl) 1963-05-29 1964-09-16
BE755940A (fr) * 1969-09-09 1971-03-09 Hoechst Ag Azetidinones-2 portant des substituants en position 4 et leur preparation
GB1368074A (en) * 1971-02-04 1974-09-25 Beecham Group Ltd Substituted beta-lactams and their preparation
FR2143211B1 (nl) * 1971-06-24 1975-10-31 Fujisawa Pharmaceutical Co
JPS4854056A (nl) * 1971-11-12 1973-07-30
US4070477A (en) * 1975-12-08 1978-01-24 Ciba-Geigy Corporation 2-Penem compounds
IN149747B (nl) * 1977-06-07 1982-04-03 Pfizer
JPS5439090A (en) * 1977-07-13 1979-03-24 Glaxo Group Ltd Betaalactam compound and its preparation
GB2005246A (en) * 1977-07-13 1979-04-19 Glaxo Group Ltd beta -Lactam compounds and processes for their preparation
US4155912A (en) * 1977-12-14 1979-05-22 Bristol-Myers Company 2-Methylpenem-3-carboxylic acid antibiotics
US4169833A (en) * 1977-12-14 1979-10-02 Bristol-Myers Company Novel phosphorane intermediates for use in preparing penem antibiotics
US4192801A (en) * 1978-04-27 1980-03-11 Bristol-Myers Company Novel phosphorane intermediates for use in preparing penem antibiotics
US4182711A (en) * 1978-04-27 1980-01-08 Bristol-Myers Company Antibacterial agents of the β-lactam type
US4282150A (en) * 1978-12-18 1981-08-04 Bristol-Myers Company 2,6-Disubstituted penem compounds
US4272437A (en) * 1978-12-18 1981-06-09 Bristol-Myers Company Antibacterial agents, and 4-thio azetidinone intermediates

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0002210A1 (en) * 1977-11-17 1979-06-13 Merck & Co. Inc. 6- and 6,6- disubstituted-2-substituted-pen-2-em-3-carboxylic acids; processes for their preparation and pharmaceutical compositions containing such compounds

Also Published As

Publication number Publication date
JPS53137951A (en) 1978-12-01
FR2411179A1 (fr) 1979-07-06
FR2405950A1 (fr) 1979-05-11
FR2405949B1 (nl) 1980-10-24
FR2405955B1 (nl) 1981-07-31
ES469568A1 (es) 1980-01-01
AU3588478A (en) 1979-11-15
FR2405946B1 (nl) 1983-09-30
US4331676A (en) 1982-05-25
FR2405950B1 (nl) 1981-07-31
SE8305299D0 (sv) 1983-09-29
FR2422637B1 (nl) 1982-04-23
FR2405934B1 (nl) 1980-09-05
US4518533A (en) 1985-05-21
FR2422637A1 (fr) 1979-11-09
FR2405945B1 (nl) 1982-04-09
FR2405934A1 (fr) 1979-05-11
DE2819655A1 (de) 1978-11-23
FR2405949A1 (fr) 1979-05-11
LU77306A1 (nl) 1979-01-18
CH646173A5 (de) 1984-11-15
FR2411179B1 (nl) 1982-04-23
US4524028A (en) 1985-06-18
FR2405945A1 (fr) 1979-05-11
SE7805217L (sv) 1978-11-10
GB1604751A (en) 1981-12-16
FR2405946A1 (fr) 1979-05-11
GB1604754A (en) 1981-12-16
AU527917B2 (en) 1983-03-31
US4447360A (en) 1984-05-08
US4515717A (en) 1985-05-07
SE443980B (sv) 1986-03-17
GB1604752A (en) 1981-12-16
SE8305299L (sv) 1983-09-29
GB1604753A (en) 1981-12-16
BE866845A (fr) 1978-11-09
DK200578A (da) 1978-11-10
FR2405955A1 (fr) 1979-05-11

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Legal Events

Date Code Title Description
A85 Still pending on 85-01-01
BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
BV The patent application has lapsed