LTC3209302I2 - - Google Patents

Info

Publication number
LTC3209302I2
LTC3209302I2 LTPA2023519C LTPA2023519C LTC3209302I2 LT C3209302 I2 LTC3209302 I2 LT C3209302I2 LT PA2023519 C LTPA2023519 C LT PA2023519C LT PA2023519 C LTPA2023519 C LT PA2023519C LT C3209302 I2 LTC3209302 I2 LT C3209302I2
Authority
LT
Lithuania
Application number
LTPA2023519C
Other languages
Lithuanian (lt)
Original Assignee
Abbvie Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=54478240&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LTC3209302(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Abbvie Inc. filed Critical Abbvie Inc.
Publication of LTPA2023519I1 publication Critical patent/LTPA2023519I1/lt
Publication of LTC3209302I2 publication Critical patent/LTC3209302I2/lt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/661Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/661Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
    • A61K31/6615Compounds having two or more esterified phosphorus acid groups, e.g. inositol triphosphate, phytic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C281/00Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
    • C07C281/02Compounds containing any of the groups, e.g. carbazates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/01Sulfonic acids
    • C07C309/02Sulfonic acids having sulfo groups bound to acyclic carbon atoms
    • C07C309/24Sulfonic acids having sulfo groups bound to acyclic carbon atoms of a carbon skeleton containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00Compounds having —CHO groups
    • C07C47/20Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
    • C07C47/277Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing ether groups, groups, groups, or groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/06Phosphorus compounds without P—C bonds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/06Phosphorus compounds without P—C bonds
    • C07F9/08Esters of oxyacids of phosphorus
    • C07F9/09Esters of phosphoric acids
    • C07F9/094Esters of phosphoric acids with arylalkanols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
LTPA2023519C 2014-10-21 2023-06-08 LTC3209302I2 (en:Method)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462066771P 2014-10-21 2014-10-21
PCT/US2015/056686 WO2016065019A1 (en) 2014-10-21 2015-10-21 Carbidopa and l-dopa prodrugs and their use to treat parkinson's disease

Publications (2)

Publication Number Publication Date
LTPA2023519I1 LTPA2023519I1 (en:Method) 2023-06-26
LTC3209302I2 true LTC3209302I2 (en:Method) 2025-10-10

Family

ID=54478240

Family Applications (2)

Application Number Title Priority Date Filing Date
LTEP15791424.3T LT3209302T (lt) 2014-10-21 2015-10-21 Provaistai karbidopa ir l-dopa ir jų panaudojimas parkinsono ligai gydyti
LTPA2023519C LTC3209302I2 (en:Method) 2014-10-21 2023-06-08

Family Applications Before (1)

Application Number Title Priority Date Filing Date
LTEP15791424.3T LT3209302T (lt) 2014-10-21 2015-10-21 Provaistai karbidopa ir l-dopa ir jų panaudojimas parkinsono ligai gydyti

Country Status (37)

Country Link
US (7) US9446059B2 (en:Method)
EP (3) EP3569587A1 (en:Method)
JP (6) JP6567049B2 (en:Method)
KR (3) KR20240113982A (en:Method)
CN (4) CN107206013A (en:Method)
AR (1) AR102389A1 (en:Method)
AU (4) AU2015335941B2 (en:Method)
BR (1) BR112017008198B1 (en:Method)
CA (1) CA2965379A1 (en:Method)
CY (2) CY1121826T1 (en:Method)
DK (1) DK3209302T3 (en:Method)
ES (1) ES2739536T3 (en:Method)
FI (1) FIC20230014I1 (en:Method)
FR (1) FR23C1035I2 (en:Method)
HR (1) HRP20191285T1 (en:Method)
HU (2) HUE044115T2 (en:Method)
IL (3) IL251829B (en:Method)
LT (2) LT3209302T (en:Method)
LU (1) LUC00304I2 (en:Method)
MX (2) MX393568B (en:Method)
MY (1) MY189519A (en:Method)
NL (1) NL301224I2 (en:Method)
NO (1) NO2023013I1 (en:Method)
PH (1) PH12017500746B1 (en:Method)
PL (1) PL3209302T3 (en:Method)
PT (1) PT3209302T (en:Method)
RS (1) RS58972B1 (en:Method)
RU (2) RU2743347C2 (en:Method)
SA (1) SA521421115B1 (en:Method)
SG (1) SG11201703170RA (en:Method)
SI (1) SI3209302T1 (en:Method)
SM (1) SMT201900376T1 (en:Method)
TR (1) TR201908296T4 (en:Method)
TW (2) TWI755257B (en:Method)
UA (1) UA120437C2 (en:Method)
WO (1) WO2016065019A1 (en:Method)
ZA (1) ZA201702760B (en:Method)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112016021034A8 (pt) 2014-03-13 2021-06-29 Neuroderm Ltd composição farmacêutica, uso da mesma e kit
US10258585B2 (en) 2014-03-13 2019-04-16 Neuroderm, Ltd. DOPA decarboxylase inhibitor compositions
TWI755257B (zh) * 2014-10-21 2022-02-11 美商艾伯維有限公司 卡比多巴及左旋多巴之前藥及使用方法
US20190224220A1 (en) * 2016-04-20 2019-07-25 Abbvie Inc. Carbidopa and L-Dopa Prodrugs and Methods of Use
WO2017223182A1 (en) * 2016-06-22 2017-12-28 Medchem Partners, Llc. Nitric oxide donors
WO2018154447A1 (en) * 2017-02-21 2018-08-30 Neuroderm Ltd Dopa decarboxylase inhibitor compositions
US20180311238A1 (en) * 2017-04-28 2018-11-01 Saniona A/S Selective Agonist Of a6 Containing nAChRs
WO2019097120A1 (en) 2017-11-16 2019-05-23 Orion Corporation New use and pharmaceutical dosage forms
MA50800A (fr) 2017-11-24 2020-09-30 H Lundbeck As Nouveaux promédicaments de catécholamine destinés à être utilisés dans le traitement de la maladie de parkinson
CN110294789A (zh) * 2018-03-21 2019-10-01 海南大学 含多巴寡肽的合成方法及其在抗帕金森病前药方面的应用
EP3849533A4 (en) 2018-09-13 2022-06-22 University of Canberra Methods of inhibition
CA3117983A1 (en) * 2018-11-15 2020-05-22 Abbvie Inc. Pharmaceutical formulations for subcutaneous administration
WO2020178810A1 (en) * 2019-03-04 2020-09-10 Neuroderm, Ltd. Pharmaceutical compositions comprising levodopa amide derivatives and uses thereof
US11111263B2 (en) 2019-05-20 2021-09-07 H. Lundbeck A/S Process for the manufacture of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4aR,10aR)-7-hydroxy-1-propyl-1,2,3,4,4a,5,10,10a-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid
US11104697B2 (en) 2019-05-20 2021-08-31 H. Lundbeck A/S Process for the manufacture of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4AR,10AR)-7-hydroxy-1- propyl-1,2,3,4,4A,5,10,10A-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid
US11130775B2 (en) 2019-05-20 2021-09-28 H. Lundbeck A/S Solid forms of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4aR,10aR)-7-hydroxy-1-propyl-1,2,3,4,4A,5,10,10A-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid
US11168056B2 (en) 2019-05-20 2021-11-09 H. Lundbeck A/S Process for the manufacturing of (6aR,10aR)-7-propyl-6,6a,7,8,9,10,10a,11-octahydro-[1,3]dioxolo[4′,5′:5,6]benzo[1,2-G]quinoline and (4aR,10aR)-1-propyl-1,2,3,4,4a,5,10,10a-octahydro-benzo[G]quinoline-6,7-diol
CN113727979B (zh) 2019-05-21 2024-09-20 H.隆德贝克有限公司 用于治疗帕金森病的新儿茶酚胺前药
JP7562562B2 (ja) 2019-05-21 2024-10-07 ハー・ルンドベック・アクチエゼルスカベット パーキンソン病の治療に使用するための新規なカテコールアミンプロドラッグ
WO2020234275A1 (en) 2019-05-21 2020-11-26 H. Lundbeck A/S New catecholamine prodrugs for use in the treatment of parkinson's diseases
JP7696829B2 (ja) 2019-05-21 2025-06-23 ハー・ルンドベック・アクチエゼルスカベット パーキンソン病の治療に使用するためのカテコールアミンカルバメートプロドラッグ
US11844754B2 (en) 2020-11-17 2023-12-19 Neuroderm, Ltd. Methods for treatment of Parkinson's disease
US11331293B1 (en) 2020-11-17 2022-05-17 Neuroderm, Ltd. Method for treatment of Parkinson's disease
US11213502B1 (en) 2020-11-17 2022-01-04 Neuroderm, Ltd. Method for treatment of parkinson's disease
EP4223288B1 (en) 2022-02-07 2024-03-06 Berlirem GmbH Novel kit of pharmaceutical preparations for the treatment of parkinson's disease
US12161612B2 (en) 2023-04-14 2024-12-10 Neuroderm, Ltd. Methods and compositions for reducing symptoms of Parkinson's disease

Family Cites Families (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3132171A (en) * 1962-06-18 1964-05-05 Strong Cobb Arner Inc 3, 4-diphosphatophenyl-alanine and process for making same
US4016288A (en) * 1975-08-13 1977-04-05 Merck & Co., Inc. Compositions and method of treating hypertension
DD230865B1 (de) * 1982-08-09 1987-05-20 Dresden Arzneimittel Verfahren zur herstellung von hydrazinocarbonsaeurederivaten durch n-aminierung von aminocarbonsaeurederivaten
US4618484A (en) 1983-03-30 1986-10-21 Yale University Composition and method for treatment of melanomas
US4508706A (en) * 1983-03-30 1985-04-02 Yale University Composition for increasing melanin in mammalian skin and hair
IT1213182B (it) * 1984-06-25 1989-12-14 Simes Derivati di composti a struttura catecolamminica.
US4616484A (en) 1984-11-30 1986-10-14 Kysor Industrial Corporation Vehicle refrigerant heating and cooling system
IT1200427B (it) 1985-03-22 1989-01-18 Afros Spa Procedimento ed impianto per lo stampaggio di pezzi in materiale plastico espanso,con parti o inserti preformati a spruzzo nello stesso stampo di formatura
JPH02138A (ja) 1987-09-18 1990-01-05 Banyu Pharmaceut Co Ltd L‐ドーパ誘導体
IT1226727B (it) 1988-07-29 1991-02-05 Simes Farmaci precursori della dopamina.
DE69016688T2 (de) * 1989-04-20 1995-10-05 Zambon Spa Dopamin-Medikament-Vorstufe.
GB9102812D0 (en) 1991-02-11 1991-03-27 Enzymatix Ltd Compounds
IT1255471B (it) 1992-07-30 1995-11-02 Zambon Spa Derivati di catecolammine,processo per la loro preparazione e composizioni farmaceutiche che li contengono
SE9203594D0 (sv) 1992-11-30 1992-11-30 Christer Nystroem Laekemedel i dispersa system
US6576766B1 (en) * 1997-11-12 2003-06-10 Ariad Pharmaceuticals, Inc. Signal transduction inhibitors, compositions containing them
US6365180B1 (en) 1998-01-20 2002-04-02 Glenn A. Meyer Oral liquid compositions
US6204257B1 (en) 1998-08-07 2001-03-20 Universtiy Of Kansas Water soluble prodrugs of hindered alcohols
KR20050016449A (ko) * 2002-05-29 2005-02-21 임팩스 라보라토리즈, 인코포레이티드 레보도파/카르비도파의 즉시 방출 및 제어 방출 조합 투여형
WO2004000863A1 (ja) 2002-06-20 2003-12-31 Nippon Suisan Kaisha, Ltd. プロドラッグ、その医薬としての使用、およびその製法
WO2004052841A1 (en) 2002-12-06 2004-06-24 Xenoport, Inc. Carbidopa prodrugs and uses thereof
WO2004069146A2 (en) 2003-02-07 2004-08-19 Yissum Research Development Company Of The Hebrew University Of Jerusalem L-dopa amide derivatives and uses thereof
ES2360759T3 (es) * 2003-08-29 2011-06-08 Centocor Ortho Biotech Inc. Composiciones farmacéuticas y procedimiento de utilización de la levodopa y de la carbidopa.
AU2004270174B2 (en) 2003-08-29 2010-05-20 Transform Pharmaceuticals, Inc. Pharmaceutical compositions and method of using levodopa and carbidopa
CA2543227A1 (en) 2003-10-31 2005-05-12 Alza Corporation Administration of levodopa and carbidopa
EP1751087B1 (en) 2004-06-04 2012-06-27 XenoPort, Inc. Levodopa derivatives, and compositions and uses thereof
NZ552276A (en) 2004-07-06 2011-03-31 Abbott Lab Prodrugs of HIV protease inhibitors
BRPI0619425A2 (pt) * 2005-12-05 2011-10-04 Xenoport Inc mesilato de pró-fármaco de levedopa, composição farmacêutica, método de preparar (2s)-2- amino-3-(3,4-diidróxi fenil) propanoato de mesilato de (2r)-2- fenil carbonilóxi propila e uso do referido composto
JP2009543761A (ja) * 2006-05-31 2009-12-10 ゾルファイ ファーマスーティカルズ ゲゼルシャフト ミット ベシュレンクテル ハフツング レボドパ/カルビドパの長期間24時間腸内投与
CA2654557A1 (en) * 2006-06-16 2007-12-21 Solvay Pharmaceuticals B.V. Combination preparations comprising bifeprunox and l-dopa
CA2673336A1 (en) 2006-12-21 2008-06-26 Xenoport, Inc. Levodopa dimethyl-substituted diester prodrugs, compositions, and methods of use
GB0713189D0 (en) 2007-07-06 2007-08-15 Proximagen Ltd Amino acid derivatives
PT2252284E (pt) * 2008-02-06 2011-08-23 Wockhardt Research Center COMPOSIÇÕES FARMACjUTICAS DE ENTACAPONE, LEVODOPA E CARBIDOPA COM BIODISPONIBILIDADE MELHORADA
JP5757864B2 (ja) 2008-05-20 2015-08-05 ニューロジェシックス, インコーポレイテッド 水溶性アセトアミノフェン類似体
BRPI1011031B8 (pt) 2009-05-19 2021-05-25 Neuroderm Ltd composição líquida farmaceuticamente aceitável e kit
US20130253056A1 (en) 2009-05-19 2013-09-26 Neuroderm, Ltd. Continuous Administration of Levodopa and/or Dopa Decarboxylase Inhibitors and Compositions for Same
EP2515876B1 (en) 2009-11-09 2016-01-06 XenoPort, Inc. Pharmaceutical compositions and oral dosage forms of a levodopa prodrug and methods of use
WO2011109767A2 (en) 2010-03-04 2011-09-09 University Of Notre Dame Du Lac Gelatinase inhibitors and prodrugs
DK3326615T3 (da) 2010-11-15 2020-03-09 Neuroderm Ltd Kontinuerlig indgivelse af l-dopa-, dopa- decarboxylase-inhibitorer, catechol-o-methyltransferaseinhibitorer og sammensætninger til samme
DK2647619T3 (en) 2010-12-02 2015-03-02 Ono Pharmaceutical Co NEW RELATIONSHIP AND MEDICAL USE THEREOF
AU2011341316A1 (en) 2010-12-10 2013-07-04 Synagile Corporation Subcutaneously infusible levodopa prodrug compositions and methods of infusion
US8765189B2 (en) * 2011-05-13 2014-07-01 Howmedica Osteonic Corp. Organophosphorous and multivalent metal compound compositions and methods
KR20130070371A (ko) * 2011-12-19 2013-06-27 울산대학교 산학협력단 퇴행성 신경질환 예방 또는 치료용 조성물
PT2968218T (pt) 2013-03-13 2021-09-24 Neuroderm Ltd Combinação para tratamento da doença de parkinson
CA2917145C (en) 2013-03-15 2023-10-24 Techfields Pharma Co., Ltd. Novel high penetration drugs and their compositions thereof for treatment of parkinson diseases
TWI755257B (zh) 2014-10-21 2022-02-11 美商艾伯維有限公司 卡比多巴及左旋多巴之前藥及使用方法
MA41377A (fr) 2015-01-20 2017-11-28 Abbvie Inc Gel intestinal de lévodopa et de carbidona et procédés d'utilisation
US20190224220A1 (en) 2016-04-20 2019-07-25 Abbvie Inc. Carbidopa and L-Dopa Prodrugs and Methods of Use
WO2018059739A1 (en) 2016-09-29 2018-04-05 Berlirem Gmbh L-dopa derivatives for the treatment of neurological diseases
WO2018154447A1 (en) 2017-02-21 2018-08-30 Neuroderm Ltd Dopa decarboxylase inhibitor compositions

Also Published As

Publication number Publication date
LUC00304I2 (en:Method) 2025-09-22
MX2017005236A (es) 2017-07-26
KR20240113982A (ko) 2024-07-23
JP6567049B2 (ja) 2019-08-28
HRP20191285T1 (hr) 2019-10-18
NZ730996A (en) 2024-04-26
US20180079762A1 (en) 2018-03-22
CA2965379A1 (en) 2016-04-28
CY2023010I2 (el) 2023-06-09
MX393568B (es) 2025-03-24
IL251829A0 (en) 2017-06-29
MY189519A (en) 2022-02-16
US11091507B2 (en) 2021-08-17
CN111494395B (zh) 2024-06-21
UA120437C2 (uk) 2019-12-10
CN111454290A (zh) 2020-07-28
US20160362431A1 (en) 2016-12-15
PT3209302T (pt) 2019-07-19
US20230106081A1 (en) 2023-04-06
SG11201703170RA (en) 2017-05-30
IL251829B (en) 2019-09-26
US20190375770A1 (en) 2019-12-12
NZ769153A (en) 2024-04-26
RU2743347C2 (ru) 2021-02-17
WO2016065019A1 (en) 2016-04-28
EP3209302B1 (en) 2019-04-24
RU2017117413A (ru) 2018-11-26
BR112017008198A2 (pt) 2017-12-26
FR23C1035I1 (fr) 2023-12-08
HUS2300009I1 (hu) 2023-03-28
PH12017500746A1 (en) 2017-10-30
JP7688087B2 (ja) 2025-06-03
US20200262852A1 (en) 2020-08-20
NL301224I1 (en:Method) 2023-03-29
NL301224I2 (nl) 2023-08-16
CN111494395A (zh) 2020-08-07
CY2023010I1 (el) 2023-06-09
TWI755257B (zh) 2022-02-11
US20220153765A1 (en) 2022-05-19
JP2017537066A (ja) 2017-12-14
CN111362980A (zh) 2020-07-03
PL3209302T3 (pl) 2019-10-31
AR102389A1 (es) 2017-02-22
LTPA2023519I1 (en:Method) 2023-06-26
SI3209302T1 (sl) 2019-06-28
CY1121826T1 (el) 2020-07-31
JP6750076B2 (ja) 2020-09-02
AU2021201414B2 (en) 2023-05-11
EP3209302A1 (en) 2017-08-30
IL268885B (en) 2020-08-31
ES2739536T3 (es) 2020-01-31
AU2015335941A1 (en) 2017-05-04
TR201908296T4 (tr) 2019-06-21
US10730895B2 (en) 2020-08-04
KR102537018B1 (ko) 2023-05-30
AU2015335941B2 (en) 2021-04-01
JP2019218356A (ja) 2019-12-26
HUE044115T2 (hu) 2019-10-28
IL268885A (en) 2019-10-31
US9446059B2 (en) 2016-09-20
TW202131931A (zh) 2021-09-01
TW201630924A (zh) 2016-09-01
BR112017008198B1 (pt) 2021-02-09
CN107206013A (zh) 2017-09-26
JP2025118978A (ja) 2025-08-13
MX381069B (es) 2025-03-12
RS58972B1 (sr) 2019-08-30
JP2023174770A (ja) 2023-12-08
SA521421115B1 (ar) 2022-03-01
MX2021003840A (es) 2022-06-30
KR20170071599A (ko) 2017-06-23
AU2023210650A1 (en) 2023-08-24
IL276493A (en) 2020-09-30
DK3209302T3 (da) 2019-05-13
FIC20230014I1 (fi) 2023-03-31
EP3569587A1 (en) 2019-11-20
US20160106765A1 (en) 2016-04-21
AU2025238004A1 (en) 2025-10-16
FR23C1035I2 (fr) 2025-04-18
NO2023013I1 (no) 2023-03-20
RU2017117413A3 (en:Method) 2019-05-30
JP6932227B2 (ja) 2021-09-08
KR20230066484A (ko) 2023-05-15
SMT201900376T1 (it) 2019-09-09
AU2021201414A1 (en) 2021-03-25
CN111362980B (zh) 2022-10-18
RU2021103000A (ru) 2021-03-01
ZA201702760B (en) 2022-05-25
JP2020189864A (ja) 2020-11-26
PH12017500746B1 (en) 2021-12-15
EP4186510A1 (en) 2023-05-31
LT3209302T (lt) 2019-06-10
TWI718999B (zh) 2021-02-21
CN111454290B (zh) 2022-12-23
JP2021183628A (ja) 2021-12-02
US10174061B2 (en) 2019-01-08

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