LT5354B - Ląstelių linijų išskyrimo baltymų neturinčioje terpėje būdas ir šiuo būdu išskirtos ląstelių linijos - Google Patents

Ląstelių linijų išskyrimo baltymų neturinčioje terpėje būdas ir šiuo būdu išskirtos ląstelių linijos Download PDF

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Publication number
LT5354B
LT5354B LT2005053A LT2005053A LT5354B LT 5354 B LT5354 B LT 5354B LT 2005053 A LT2005053 A LT 2005053A LT 2005053 A LT2005053 A LT 2005053A LT 5354 B LT5354 B LT 5354B
Authority
LT
Lithuania
Prior art keywords
protein
protein concentration
cell line
cells
medium
Prior art date
Application number
LT2005053A
Other languages
English (en)
Lithuanian (lt)
Other versions
LT2005053A (en
Inventor
Rolando Perez Rodriguez
Adolfo Castillo Vitlloch
Svieta Vitores Sarazola
Tammy Boggiano Ayo
Luis Rojas Del Calvo
Original Assignee
Centro De Immunologia Molecular
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centro De Immunologia Molecular filed Critical Centro De Immunologia Molecular
Publication of LT2005053A publication Critical patent/LT2005053A/xx
Publication of LT5354B publication Critical patent/LT5354B/lt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0693—Tumour cells; Cancer cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0693—Tumour cells; Cancer cells
    • C12N5/0694—Cells of blood, e.g. leukemia cells, myeloma cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
    • C12N2500/95—Protein-free medium and culture conditions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/02—Cells for production

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
LT2005053A 2002-10-23 2005-05-19 Ląstelių linijų išskyrimo baltymų neturinčioje terpėje būdas ir šiuo būdu išskirtos ląstelių linijos LT5354B (lt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CU20020239A CU23097A1 (es) 2002-10-23 2002-10-23 Método para la obtención de líneas celulares en medio libre de proteína y líneas celulares obtenidas por este método

Publications (2)

Publication Number Publication Date
LT2005053A LT2005053A (en) 2006-04-25
LT5354B true LT5354B (lt) 2006-07-25

Family

ID=40134843

Family Applications (1)

Application Number Title Priority Date Filing Date
LT2005053A LT5354B (lt) 2002-10-23 2005-05-19 Ląstelių linijų išskyrimo baltymų neturinčioje terpėje būdas ir šiuo būdu išskirtos ląstelių linijos

Country Status (27)

Country Link
US (2) US20060036082A1 (de)
EP (2) EP2363418B1 (de)
JP (1) JP4674087B2 (de)
KR (1) KR101186048B1 (de)
CN (1) CN1714147B (de)
AR (1) AR041645A1 (de)
AT (1) ATE502103T1 (de)
AU (1) AU2003273727B2 (de)
BR (1) BR0315565B1 (de)
CA (1) CA2503315C (de)
CU (1) CU23097A1 (de)
DE (1) DE60336415D1 (de)
DK (1) DK1564285T3 (de)
EA (1) EA007465B1 (de)
EC (1) ECSP055740A (de)
ES (2) ES2360049T3 (de)
GE (1) GEP20084444B (de)
HR (1) HRP20050760A2 (de)
LT (1) LT5354B (de)
LV (1) LV13361B (de)
MY (1) MY144088A (de)
NZ (1) NZ540171A (de)
PE (1) PE20040552A1 (de)
PT (1) PT1564285E (de)
TN (1) TNSN05116A1 (de)
UY (1) UY28037A1 (de)
WO (1) WO2004038010A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104673754B (zh) * 2015-02-14 2018-03-02 百泰生物药业有限公司 重组骨髓瘤细胞克隆的筛选方法及由此获得的抗体分子
CN104651314B (zh) * 2015-02-14 2018-06-19 百泰生物药业有限公司 获得高产稳定表达细胞克隆的方法及由此获得的抗体分子

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991005240A1 (en) 1989-09-29 1991-04-18 Atomic Energy Of Canada Limited Infrared-based gas detector
US5393668A (en) 1991-09-11 1995-02-28 Hans-Wilhelm Doerr Cultivation of mammalian cells in a protein-free medium on a polyvinylformal and/or polyvinyl butyral surface
WO1996015231A2 (en) 1994-11-10 1996-05-23 Immuno Aktiengesellschaft Method for producing biologicals in protein-free culture
WO1996026266A1 (en) 1995-02-23 1996-08-29 Quest International B.V. Peptides for tissue and cell culture media
WO1997019111A2 (es) 1995-11-17 1997-05-29 Centro De Inmunologia Molecular (Cim) Anticuerpos monoclonales anti-cd6 y sus utilizaciones
JP2696001B2 (ja) 1991-04-15 1998-01-14 財団法人化学及血清療法研究所 組換え蛋白質産生用培地
US5891996A (en) 1972-09-17 1999-04-06 Centro De Inmunologia Molecular Humanized and chimeric monoclonal antibodies that recognize epidermal growth factor receptor (EGF-R); diagnostic and therapeutic use

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3694263A (en) * 1970-10-23 1972-09-26 Joseph J Korn Sr Swimming pool cleaning methods and apparatus therefor
US3886616A (en) * 1972-12-06 1975-06-03 Fay A Hayes Hand propelled swimming pool cleaner
US4275474A (en) * 1979-04-30 1981-06-30 Woodard Randle C Vacuum head for swimming pool cleaning system
US4240174A (en) * 1979-07-30 1980-12-23 Scott Jeffrey L Self-contained mobile pool cleaning apparatus
US4430214A (en) * 1982-09-15 1984-02-07 Baker Marvin E Strainer mill for swimming pool pump intake
AU2986484A (en) * 1983-06-27 1985-01-03 Monash University Leptospira strains grown in protein free medium
US4558479A (en) * 1984-01-26 1985-12-17 Alopex Industries, Inc. Pool cleaner
US4683599A (en) * 1984-03-30 1987-08-04 Fahet Nv Automatic pool cleaner fitting
US4581075A (en) * 1985-03-15 1986-04-08 Maxi-Sweep, Inc. Self-propelled water borne pool cleaner
WO1996008565A2 (en) * 1994-09-16 1996-03-21 Cancer Research Fund Of Contra Costa RECOMBINANT PEPTIDES DERIVED FROM THE Mc3 ANTI-BA46 ANTIBODY, METHODS OF USE THEREOF, AND METHODS OF HUMANIZING ANTIBODY PEPTIDES
AUPN442295A0 (en) 1995-07-26 1995-08-17 Commonwealth Scientific And Industrial Research Organisation Regulated autocrine growth of mammalian cells
AT407255B (de) * 1997-06-20 2001-02-26 Immuno Ag Rekombinanter zellklon mit erhöhter stabilität in serum- und proteinfreiem medium und verfahren zur gewinnung des stabilen zellklons

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5891996A (en) 1972-09-17 1999-04-06 Centro De Inmunologia Molecular Humanized and chimeric monoclonal antibodies that recognize epidermal growth factor receptor (EGF-R); diagnostic and therapeutic use
WO1991005240A1 (en) 1989-09-29 1991-04-18 Atomic Energy Of Canada Limited Infrared-based gas detector
JP2696001B2 (ja) 1991-04-15 1998-01-14 財団法人化学及血清療法研究所 組換え蛋白質産生用培地
US5393668A (en) 1991-09-11 1995-02-28 Hans-Wilhelm Doerr Cultivation of mammalian cells in a protein-free medium on a polyvinylformal and/or polyvinyl butyral surface
WO1996015231A2 (en) 1994-11-10 1996-05-23 Immuno Aktiengesellschaft Method for producing biologicals in protein-free culture
WO1996026266A1 (en) 1995-02-23 1996-08-29 Quest International B.V. Peptides for tissue and cell culture media
WO1997019111A2 (es) 1995-11-17 1997-05-29 Centro De Inmunologia Molecular (Cim) Anticuerpos monoclonales anti-cd6 y sus utilizaciones

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
MATEO C. ET AL.: "Removal of amphipathic epitopes from genetically engineered antibodies: production of modified immunoglobulins with reduced immunogenicity", HYBRIDOMA, 2000, pages 463 - 471
REITER M ET AL.: "Flow cytometry and two-dimensional electrophoresis (2-DE) for system evaluation of long term continuous perfused animal cell cultures in macroporous beads", CYTOTECHNOLOGY, 1992, pages 247 - 253

Also Published As

Publication number Publication date
TNSN05116A1 (en) 2007-05-14
EP2363418A2 (de) 2011-09-07
EA200500695A1 (ru) 2005-10-27
EP1564285A1 (de) 2005-08-17
CA2503315C (en) 2014-02-18
UY28037A1 (es) 2004-04-30
WO2004038010A1 (es) 2004-05-06
HRP20050760A2 (en) 2006-08-31
KR101186048B1 (ko) 2012-09-25
US20060036082A1 (en) 2006-02-16
ES2360049T3 (es) 2011-05-31
US20100197011A1 (en) 2010-08-05
AU2003273727B2 (en) 2008-04-03
ATE502103T1 (de) 2011-04-15
BR0315565A (pt) 2005-08-23
CN1714147B (zh) 2011-01-12
DE60336415D1 (de) 2011-04-28
CU23097A1 (es) 2005-11-18
ES2624279T3 (es) 2017-07-13
CN1714147A (zh) 2005-12-28
EA007465B1 (ru) 2006-10-27
PT1564285E (pt) 2011-04-20
JP2006503879A (ja) 2006-02-02
AR041645A1 (es) 2005-05-26
NZ540171A (en) 2008-04-30
PE20040552A1 (es) 2004-10-26
DK1564285T3 (da) 2011-05-16
KR20050088403A (ko) 2005-09-06
LT2005053A (en) 2006-04-25
ECSP055740A (es) 2005-09-20
CA2503315A1 (en) 2004-05-06
GEP20084444B (en) 2008-08-10
MY144088A (en) 2011-08-15
BR0315565B1 (pt) 2022-01-25
EP2363418B1 (de) 2017-02-08
AU2003273727A1 (en) 2004-05-13
LV13361B (en) 2006-02-20
EP1564285B1 (de) 2011-03-16
HK1084414A1 (en) 2006-07-28
EP2363418A3 (de) 2011-11-16
JP4674087B2 (ja) 2011-04-20

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