LT3977B - Dialkoxy-pyridinyl-benzimidazole derivatives, process for their preparation and their pharmaceutical use - Google Patents
Dialkoxy-pyridinyl-benzimidazole derivatives, process for their preparation and their pharmaceutical use Download PDFInfo
- Publication number
- LT3977B LT3977B LTIP1713A LTIP1713A LT3977B LT 3977 B LT3977 B LT 3977B LT IP1713 A LTIP1713 A LT IP1713A LT IP1713 A LTIP1713 A LT IP1713A LT 3977 B LT3977 B LT 3977B
- Authority
- LT
- Lithuania
- Prior art keywords
- methyl
- compound
- benzimidazole
- pyridinyl
- mmol
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9002206A SE9002206D0 (sv) | 1990-06-20 | 1990-06-20 | New compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
LTIP1713A LTIP1713A (en) | 1995-08-25 |
LT3977B true LT3977B (en) | 1996-06-25 |
Family
ID=20379831
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
LTIP1713A LT3977B (en) | 1990-06-20 | 1993-12-30 | Dialkoxy-pyridinyl-benzimidazole derivatives, process for their preparation and their pharmaceutical use |
LTIP1712A LT3952B (en) | 1990-06-20 | 1993-12-30 | Substituted benzimidazoles, process for their preparation and their pharmaceutical use |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
LTIP1712A LT3952B (en) | 1990-06-20 | 1993-12-30 | Substituted benzimidazoles, process for their preparation and their pharmaceutical use |
Country Status (26)
Country | Link |
---|---|
EP (1) | EP0535081A1 (ja) |
JP (1) | JPH05507713A (ja) |
CN (1) | CN1058212A (ja) |
AP (1) | AP215A (ja) |
AU (1) | AU649453B2 (ja) |
CA (1) | CA2083714A1 (ja) |
CZ (1) | CZ279772B6 (ja) |
FI (1) | FI925766A (ja) |
HU (1) | HUT62881A (ja) |
IE (1) | IE912025A1 (ja) |
IL (1) | IL98470A0 (ja) |
IS (1) | IS3721A7 (ja) |
LT (2) | LT3977B (ja) |
LV (1) | LV10953A (ja) |
MA (1) | MA22199A1 (ja) |
NO (1) | NO924775D0 (ja) |
NZ (1) | NZ238546A (ja) |
OA (1) | OA09682A (ja) |
PT (1) | PT98035A (ja) |
RO (1) | RO110493B1 (ja) |
SE (1) | SE9002206D0 (ja) |
TN (1) | TNSN91049A1 (ja) |
TW (1) | TW216418B (ja) |
WO (1) | WO1991019711A1 (ja) |
YU (1) | YU104191A (ja) |
ZA (2) | ZA914297B (ja) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE9002043D0 (sv) * | 1990-06-07 | 1990-06-07 | Astra Ab | Improved method for synthesis |
SE9103776D0 (sv) * | 1991-12-19 | 1991-12-19 | Astra Ab | New compounds |
IS4232A (is) * | 1993-12-06 | 1995-06-07 | Astra Aktiebolag | Súbstitúerað bensimidasól, aðferðir við framleiðslu þess og lyfjafræðileg notkun |
SE9500422D0 (sv) * | 1995-02-06 | 1995-02-06 | Astra Ab | New oral pharmaceutical dosage forms |
SE9500478D0 (sv) * | 1995-02-09 | 1995-02-09 | Astra Ab | New pharmaceutical formulation and process |
SE9600070D0 (sv) | 1996-01-08 | 1996-01-08 | Astra Ab | New oral pharmaceutical dosage forms |
AU5424500A (en) | 2000-02-24 | 2001-09-03 | Kopran Res Lab Ltd | Orally administrable acid stable anti-ulcer benzimidazole derivatives |
SE0101379D0 (sv) | 2001-04-18 | 2001-04-18 | Diabact Ab | Komposition som hämmar utsöndring av magsyra |
US8206741B2 (en) | 2001-06-01 | 2012-06-26 | Pozen Inc. | Pharmaceutical compositions for the coordinated delivery of NSAIDs |
KR101061351B1 (ko) | 2002-04-09 | 2011-08-31 | 플라멜 테크놀로지스 | 활성 성분 마이크로캡슐의 경구 현탁액 |
SE0203065D0 (sv) | 2002-10-16 | 2002-10-16 | Diabact Ab | Gastric acid secretion inhibiting composition |
ATE544447T1 (de) | 2003-09-26 | 2012-02-15 | Alza Corp | Arzneistoffcoating mit hohem wirkstoffanteil sowie methoden zu dessen herstellung |
TW200606163A (en) | 2004-04-22 | 2006-02-16 | Eisai Co Ltd | Imidazopyridine compound |
US8541026B2 (en) | 2004-09-24 | 2013-09-24 | Abbvie Inc. | Sustained release formulations of opioid and nonopioid analgesics |
US20070015782A1 (en) | 2005-04-15 | 2007-01-18 | Eisai Co., Ltd. | Benzimidazole compound |
US9040564B2 (en) | 2005-04-28 | 2015-05-26 | Eisai R&D Management Co., Ltd. | Stabilized composition |
US7981908B2 (en) | 2005-05-11 | 2011-07-19 | Vecta, Ltd. | Compositions and methods for inhibiting gastric acid secretion |
US7803817B2 (en) | 2005-05-11 | 2010-09-28 | Vecta, Ltd. | Composition and methods for inhibiting gastric acid secretion |
WO2007122686A1 (ja) * | 2006-04-14 | 2007-11-01 | Eisai R & D Management Co., Ltd. | ベンズイミダゾール化合物 |
PL2046334T3 (pl) | 2006-07-25 | 2015-02-27 | Vecta Ltd | Kompozycje i sposoby hamowania wydzielania kwasów żołądkowych z wykorzystaniem pochodnych małych kwasów dikarboksylowych w połączeniu z PPI |
US20110009624A9 (en) * | 2006-10-13 | 2011-01-13 | Masato Ueda | Benzimidazole compounds having gastric acid secretion inhibitory action |
US9220698B2 (en) | 2008-09-09 | 2015-12-29 | Pozen Inc. | Method for delivering a pharmaceutical composition to patient in need thereof |
EA201290026A1 (ru) | 2009-06-25 | 2012-07-30 | Астразенека Аб | Способ лечения пациента, имеющего риск развития язвы, связанной с приемом нестероидных противовоспалительных средств (nsaid) |
WO2011080502A2 (en) | 2009-12-29 | 2011-07-07 | Orexo Ab | New pharmaceutical dosage form for the treatment of gastric acid-related disorders |
EP2519229A2 (en) | 2009-12-29 | 2012-11-07 | Novartis AG | New pharmaceutical dosage form for the treatment of gastric acid-related disorders |
WO2011080500A2 (en) | 2009-12-29 | 2011-07-07 | Orexo Ab | New pharmaceutical dosage form for the treatment of gastric acid-related disorders |
EP2601947A1 (en) | 2011-12-05 | 2013-06-12 | Abo Bakr Mohammed Ali Al-Mehdar | Fixed-dose combination for treatment of helicobacter pylori associated diseases |
UA115139C2 (uk) | 2011-12-28 | 2017-09-25 | Поузен Інк. | Спосіб доставки фармацевтичної композиції, яка містить омепразол й ацетилсаліцилову кислоту, пацієнту |
KR20240042153A (ko) * | 2016-09-14 | 2024-04-01 | 위펑 제인 쳉 | D-아미노산 옥시다제 (daao) 저해제로서 신규한 치환된 벤즈이미다졸 유도체 |
Citations (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1500043A (en) | 1974-02-18 | 1978-02-08 | Haessle Ab | Benzimidazole derivatives their preparation and their use in affecting gastric acid secretion |
GB1525958A (en) | 1974-05-16 | 1978-09-27 | Haessle Ab | 2-(heterocyclic substituted alkylsulphinyl)-benzimidazoles and their pharmaceutical compositions |
US4182766A (en) | 1977-09-19 | 1980-01-08 | Hoffmann-La Roche Inc. | Naphth[2,3-d]imidazoles |
US4255431A (en) | 1978-04-14 | 1981-03-10 | Aktiebolaget Hassle | Gastric acid secretion inhibiting substituted 2-(2-benzimidazolyl)-pyridines, pharmaceutical preparations containing same, and method for inhibiting gastric acid secretion |
US4359465A (en) | 1980-07-28 | 1982-11-16 | The Upjohn Company | Methods for treating gastrointestinal inflammation |
BE898880A (fr) | 1983-02-11 | 1984-08-10 | Haessle Ab | Nouveaux benzimidazoles, preparations pharmaceutiques qui les contiennent et leur preparation |
EP0124495A2 (en) | 1983-03-04 | 1984-11-07 | Aktiebolaget Hässle | Omeprazole salts |
US4599347A (en) | 1980-08-21 | 1986-07-08 | Hoffmann-La Roche Inc. | Tetrahydro-naphth (2.3-d) imidazole derivatives |
EP0208452A2 (en) | 1985-07-02 | 1987-01-14 | Takeda Chemical Industries, Ltd. | Pyridine derivatives, their production and use |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL75400A (en) * | 1984-06-16 | 1988-10-31 | Byk Gulden Lomberg Chem Fab | Dialkoxypyridine methyl(sulfinyl or sulfonyl)benzimidazoles,processes for the preparation thereof and pharmaceutical compositions containing the same |
AU568441B2 (en) * | 1984-09-24 | 1987-12-24 | Upjohn Company, The | 2-(pyridylalkenesulfinyl) benzimidazole derivatives |
IL76839A (en) * | 1984-10-31 | 1988-08-31 | Byk Gulden Lomberg Chem Fab | Picoline derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same |
SE8505112D0 (sv) * | 1985-10-29 | 1985-10-29 | Haessle Ab | Novel pharmacological compounds |
NZ234564A (en) | 1986-11-21 | 1991-04-26 | Haessle Ab | 1-substituted benzimidazoles and pharmaceutical compositions |
DE3722810A1 (de) * | 1987-07-10 | 1989-01-19 | Hoechst Ag | Substituierte benzimidazole, verfahren zu deren herstellung, diese enthaltende pharmazeutische zubereitungen und deren verwendung |
HU886738D0 (en) * | 1987-10-30 | 1990-02-28 | Haessle Ab | Process for the preparation of pharmaceutical compositions against osteoporosis containing 2-pyridinyl-methyl-(sulfinyl or thio)-benzimidazoles |
JPH03501609A (ja) * | 1987-12-11 | 1991-04-11 | ビイク グルデン ロンベルク ヒエーミツシエ フアブリーク ゲゼルシヤフト ミツト ベシユレンクテル ハフツング | 新規ベンゾイミダゾール誘導体 |
JPH03504497A (ja) * | 1988-05-25 | 1991-10-03 | ビイク グルデン ロンベルク ヒエーミツシエ フアブリーク ゲゼルシヤフト ミツト ベシユレンクテル ハフツング | 新規フルオルアルコキシ化合物 |
-
1990
- 1990-06-20 SE SE9002206A patent/SE9002206D0/xx unknown
-
1991
- 1991-06-05 ZA ZA914297A patent/ZA914297B/xx unknown
- 1991-06-05 ZA ZA914296A patent/ZA914296B/xx unknown
- 1991-06-11 EP EP91911659A patent/EP0535081A1/en not_active Withdrawn
- 1991-06-11 CA CA002083714A patent/CA2083714A1/en not_active Abandoned
- 1991-06-11 RO RO92-01581A patent/RO110493B1/ro unknown
- 1991-06-11 AU AU80097/91A patent/AU649453B2/en not_active Ceased
- 1991-06-11 WO PCT/SE1991/000415 patent/WO1991019711A1/en not_active Application Discontinuation
- 1991-06-11 JP JP91511435A patent/JPH05507713A/ja active Pending
- 1991-06-11 HU HU924033A patent/HUT62881A/hu unknown
- 1991-06-12 TW TW080104582A patent/TW216418B/zh active
- 1991-06-12 IL IL98470A patent/IL98470A0/xx unknown
- 1991-06-12 YU YU104191A patent/YU104191A/sh unknown
- 1991-06-14 NZ NZ238546A patent/NZ238546A/en unknown
- 1991-06-14 IE IE202591A patent/IE912025A1/en unknown
- 1991-06-18 MA MA22462A patent/MA22199A1/fr unknown
- 1991-06-19 TN TNTNSN91049A patent/TNSN91049A1/fr unknown
- 1991-06-19 PT PT98035A patent/PT98035A/pt not_active Application Discontinuation
- 1991-06-19 AP APAP/P/1991/000285A patent/AP215A/en active
- 1991-06-20 IS IS3721A patent/IS3721A7/is unknown
- 1991-06-20 CN CN91105024A patent/CN1058212A/zh active Pending
- 1991-06-20 CZ CS911894A patent/CZ279772B6/cs unknown
-
1992
- 1992-11-27 OA OA60306A patent/OA09682A/en unknown
- 1992-12-10 NO NO924775A patent/NO924775D0/no unknown
- 1992-12-18 FI FI925766A patent/FI925766A/fi not_active Application Discontinuation
-
1993
- 1993-08-27 LV LV931045A patent/LV10953A/xx unknown
- 1993-12-30 LT LTIP1713A patent/LT3977B/lt not_active IP Right Cessation
- 1993-12-30 LT LTIP1712A patent/LT3952B/lt not_active IP Right Cessation
Patent Citations (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1500043A (en) | 1974-02-18 | 1978-02-08 | Haessle Ab | Benzimidazole derivatives their preparation and their use in affecting gastric acid secretion |
GB1525958A (en) | 1974-05-16 | 1978-09-27 | Haessle Ab | 2-(heterocyclic substituted alkylsulphinyl)-benzimidazoles and their pharmaceutical compositions |
US4182766A (en) | 1977-09-19 | 1980-01-08 | Hoffmann-La Roche Inc. | Naphth[2,3-d]imidazoles |
US4255431A (en) | 1978-04-14 | 1981-03-10 | Aktiebolaget Hassle | Gastric acid secretion inhibiting substituted 2-(2-benzimidazolyl)-pyridines, pharmaceutical preparations containing same, and method for inhibiting gastric acid secretion |
US4359465A (en) | 1980-07-28 | 1982-11-16 | The Upjohn Company | Methods for treating gastrointestinal inflammation |
US4599347A (en) | 1980-08-21 | 1986-07-08 | Hoffmann-La Roche Inc. | Tetrahydro-naphth (2.3-d) imidazole derivatives |
BE898880A (fr) | 1983-02-11 | 1984-08-10 | Haessle Ab | Nouveaux benzimidazoles, preparations pharmaceutiques qui les contiennent et leur preparation |
EP0124495A2 (en) | 1983-03-04 | 1984-11-07 | Aktiebolaget Hässle | Omeprazole salts |
EP0208452A2 (en) | 1985-07-02 | 1987-01-14 | Takeda Chemical Industries, Ltd. | Pyridine derivatives, their production and use |
Also Published As
Publication number | Publication date |
---|---|
YU104191A (sh) | 1994-01-20 |
LTIP1712A (en) | 1995-08-25 |
MA22199A1 (fr) | 1992-04-01 |
ZA914297B (en) | 1992-03-25 |
EP0535081A1 (en) | 1993-04-07 |
FI925766A0 (fi) | 1992-12-18 |
IE912025A1 (en) | 1992-01-01 |
LV10953A (lv) | 1995-12-20 |
CA2083714A1 (en) | 1991-12-21 |
SE9002206D0 (sv) | 1990-06-20 |
IS3721A7 (is) | 1991-12-21 |
CS189491A3 (en) | 1992-04-15 |
CN1058212A (zh) | 1992-01-29 |
CZ279772B6 (cs) | 1995-06-14 |
ZA914296B (en) | 1992-03-25 |
NO924775L (no) | 1992-12-10 |
NO924775D0 (no) | 1992-12-10 |
AP9100285A0 (en) | 1991-07-31 |
AP215A (en) | 1992-09-02 |
TNSN91049A1 (fr) | 1992-10-25 |
RO110493B1 (ro) | 1996-01-30 |
LT3952B (en) | 1996-05-27 |
TW216418B (ja) | 1993-11-21 |
LTIP1713A (en) | 1995-08-25 |
AU649453B2 (en) | 1994-05-26 |
HUT62881A (en) | 1993-06-28 |
FI925766A (fi) | 1992-12-18 |
JPH05507713A (ja) | 1993-11-04 |
NZ238546A (en) | 1994-03-25 |
HU9204033D0 (en) | 1993-03-29 |
OA09682A (en) | 1993-05-15 |
AU8009791A (en) | 1992-01-07 |
WO1991019711A1 (en) | 1991-12-26 |
IL98470A0 (en) | 1992-07-15 |
PT98035A (pt) | 1992-03-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM9A | Lapsed patents |
Effective date: 19961230 |