LT3809B - Therapeutically active fluoro substituted benzimidazoles, process for their preparation as well as their use - Google Patents

Therapeutically active fluoro substituted benzimidazoles, process for their preparation as well as their use Download PDF

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Publication number
LT3809B
LT3809B LTIP1732A LTIP1732A LT3809B LT 3809 B LT3809 B LT 3809B LT IP1732 A LTIP1732 A LT IP1732A LT IP1732 A LTIP1732 A LT IP1732A LT 3809 B LT3809 B LT 3809B
Authority
LT
Lithuania
Prior art keywords
compound
fluoro
compounds
formula
pyridinyl
Prior art date
Application number
LTIP1732A
Other languages
English (en)
Lithuanian (lt)
Inventor
Arne Elof Braendstroem
Per Lennart Lindberg
Gunnel Elisabeth Sunden
Original Assignee
Haessle Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Haessle Ab filed Critical Haessle Ab
Publication of LTIP1732A publication Critical patent/LTIP1732A/xx
Publication of LT3809B publication Critical patent/LT3809B/lt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Fertilizers (AREA)
LTIP1732A 1989-12-20 1993-12-30 Therapeutically active fluoro substituted benzimidazoles, process for their preparation as well as their use LT3809B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/454,048 US5049674A (en) 1989-12-20 1989-12-20 Therapeutically active fluoro substituted benzimidazoles

Publications (2)

Publication Number Publication Date
LTIP1732A LTIP1732A (en) 1995-08-25
LT3809B true LT3809B (en) 1996-03-25

Family

ID=23803077

Family Applications (1)

Application Number Title Priority Date Filing Date
LTIP1732A LT3809B (en) 1989-12-20 1993-12-30 Therapeutically active fluoro substituted benzimidazoles, process for their preparation as well as their use

Country Status (22)

Country Link
US (1) US5049674A (lv)
EP (1) EP0506759A1 (lv)
JP (1) JPH05502448A (lv)
KR (1) KR927003573A (lv)
CN (1) CN1052670A (lv)
AU (1) AU641465B2 (lv)
CA (1) CA2070651A1 (lv)
EG (1) EG19360A (lv)
FI (1) FI922864A0 (lv)
HU (1) HUT61995A (lv)
IE (1) IE904248A1 (lv)
IL (1) IL96397A (lv)
IS (1) IS3658A7 (lv)
LT (1) LT3809B (lv)
LV (1) LV10952A (lv)
NO (1) NO922437L (lv)
NZ (1) NZ236102A (lv)
PL (1) PL167703B1 (lv)
PT (1) PT96256A (lv)
WO (1) WO1991009028A1 (lv)
YU (1) YU47750B (lv)
ZA (1) ZA909142B (lv)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE144421T1 (de) * 1992-07-28 1996-11-15 Astra Ab Injizierbares arzneimittel und satz, die omoprazol oder verwandte verbindungenenthalten
GB9423970D0 (en) * 1994-11-28 1995-01-11 Astra Ab Oxidation
SE9600070D0 (sv) * 1996-01-08 1996-01-08 Astra Ab New oral pharmaceutical dosage forms

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US176308A (en) 1876-04-18 Improvement in buttons
GB1500043A (en) 1974-02-18 1978-02-08 Haessle Ab Benzimidazole derivatives their preparation and their use in affecting gastric acid secretion
GB1525958A (en) 1974-05-16 1978-09-27 Haessle Ab 2-(heterocyclic substituted alkylsulphinyl)-benzimidazoles and their pharmaceutical compositions
US4182766A (en) 1977-09-19 1980-01-08 Hoffmann-La Roche Inc. Naphth[2,3-d]imidazoles
US4359465A (en) 1980-07-28 1982-11-16 The Upjohn Company Methods for treating gastrointestinal inflammation
US4555518A (en) 1983-05-03 1985-11-26 Byk Gulden Lomberg Chemische Fabrik Gmbh Fluoroalkoxy substituted benzimidazoles useful as gastric acid secretion inhibitors
US4599347A (en) 1980-08-21 1986-07-08 Hoffmann-La Roche Inc. Tetrahydro-naphth (2.3-d) imidazole derivatives

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE7804231L (sv) * 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
SE8301182D0 (sv) * 1983-03-04 1983-03-04 Haessle Ab Novel compounds
JPS6150978A (ja) * 1984-08-16 1986-03-13 Takeda Chem Ind Ltd ピリジン誘導体およびその製造法
JPS6150979A (ja) * 1984-08-16 1986-03-13 Takeda Chem Ind Ltd ピリジン誘導体およびその製造法
AU568441B2 (en) * 1984-09-24 1987-12-24 Upjohn Company, The 2-(pyridylalkenesulfinyl) benzimidazole derivatives
US4738975A (en) * 1985-07-02 1988-04-19 Takeda Chemical Industries, Ltd. Pyridine derivatives, and use as anti-ulcer agents
SE8505112D0 (sv) * 1985-10-29 1985-10-29 Haessle Ab Novel pharmacological compounds
FI90544C (fi) * 1986-11-13 1994-02-25 Eisai Co Ltd Menetelmä lääkeaineina käyttökelpoisten 2-pyridin-2-yyli-metyylitio- ja sulfinyyli-1H-bensimidatsolijohdannaisten valmistamiseksi
NZ234564A (en) * 1986-11-21 1991-04-26 Haessle Ab 1-substituted benzimidazoles and pharmaceutical compositions
FI96860C (fi) * 1987-06-17 1996-09-10 Eisai Co Ltd Analogiamenetelmä lääkeaineena käytettävän pyridiinijohdannaisen valmistamiseksi
DE3722810A1 (de) * 1987-07-10 1989-01-19 Hoechst Ag Substituierte benzimidazole, verfahren zu deren herstellung, diese enthaltende pharmazeutische zubereitungen und deren verwendung
ZA889194B (en) * 1987-12-11 1989-08-30 Byk Gulden Lomberg Chemisch Fa Novel benzimidazole derivatives

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US176308A (en) 1876-04-18 Improvement in buttons
GB1500043A (en) 1974-02-18 1978-02-08 Haessle Ab Benzimidazole derivatives their preparation and their use in affecting gastric acid secretion
GB1525958A (en) 1974-05-16 1978-09-27 Haessle Ab 2-(heterocyclic substituted alkylsulphinyl)-benzimidazoles and their pharmaceutical compositions
US4182766A (en) 1977-09-19 1980-01-08 Hoffmann-La Roche Inc. Naphth[2,3-d]imidazoles
US4359465A (en) 1980-07-28 1982-11-16 The Upjohn Company Methods for treating gastrointestinal inflammation
US4599347A (en) 1980-08-21 1986-07-08 Hoffmann-La Roche Inc. Tetrahydro-naphth (2.3-d) imidazole derivatives
US4555518A (en) 1983-05-03 1985-11-26 Byk Gulden Lomberg Chemische Fabrik Gmbh Fluoroalkoxy substituted benzimidazoles useful as gastric acid secretion inhibitors

Also Published As

Publication number Publication date
NO922437L (no) 1992-08-13
FI922864A (fi) 1992-06-18
AU7038091A (en) 1991-07-18
NO922437D0 (no) 1992-06-19
HUT61995A (en) 1993-03-29
IE904248A1 (en) 1991-07-03
HU9202071D0 (en) 1992-09-28
NZ236102A (en) 1992-12-23
ZA909142B (en) 1991-08-28
YU47750B (sh) 1996-01-08
KR927003573A (ko) 1992-12-18
CA2070651A1 (en) 1991-06-21
WO1991009028A1 (en) 1991-06-27
US5049674A (en) 1991-09-17
LV10952A (lv) 1995-12-20
PL288337A1 (en) 1991-12-02
PT96256A (pt) 1991-09-30
PL167703B1 (en) 1995-10-31
EG19360A (en) 1994-12-30
IL96397A0 (en) 1991-08-16
IS3658A7 (is) 1991-06-21
AU641465B2 (en) 1993-09-23
JPH05502448A (ja) 1993-04-28
EP0506759A1 (en) 1992-10-07
LTIP1732A (en) 1995-08-25
FI922864A0 (fi) 1992-06-18
CN1052670A (zh) 1991-07-03
YU237190A (sh) 1994-11-15
IL96397A (en) 1995-10-31

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Effective date: 19961230