YU237190A - Aktivni fluoro-supstituisani benzimidazoli i postupci za njihovo dobijanje - Google Patents

Aktivni fluoro-supstituisani benzimidazoli i postupci za njihovo dobijanje

Info

Publication number
YU237190A
YU237190A YU237190A YU237190A YU237190A YU 237190 A YU237190 A YU 237190A YU 237190 A YU237190 A YU 237190A YU 237190 A YU237190 A YU 237190A YU 237190 A YU237190 A YU 237190A
Authority
YU
Yugoslavia
Prior art keywords
procedures
obtaining
substituted benzimidazoles
active fluoro
group
Prior art date
Application number
YU237190A
Other languages
English (en)
Other versions
YU47750B (sh
Inventor
A.E. Brandstrom
P.L. Lindberg
G.E. Sunden
Original Assignee
Aktiebolaget Hassle
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aktiebolaget Hassle filed Critical Aktiebolaget Hassle
Publication of YU237190A publication Critical patent/YU237190A/sh
Publication of YU47750B publication Critical patent/YU47750B/sh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Abstract

TERAPEUTSKI AKTIVNI FLUORO-SUPSTITUISANI BENZIMIDAZOLI I POSTUPCI ZA NJIHOVO PRAVLJENJE, pronalazak se odnosi na nova jedinjenja formule I i I': gde je F u 5 ili 6 položaju, i: pri čemu je u obe formule R grupa -CH2OCOOR1, gde je R1 pravi ili račvasti alkil koji sadrži 1-6 atoma ugljenika ili benzil, ili je R1 grupa ili -(CH2)n-SO3H gde je n 1-6 kao i njihove fiziološki prihvatljive soli i inter-medijeri, farmaceutski preparati koji sadrže takva jedinjenja kao aktivan sastojak, i korišćenje jedinjenja u medicini.
YU237190A 1989-12-20 1990-12-17 Aktivni fluorosupstituisani benzimidazoli i postupci za njihovo dobijanje YU47750B (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/454,048 US5049674A (en) 1989-12-20 1989-12-20 Therapeutically active fluoro substituted benzimidazoles

Publications (2)

Publication Number Publication Date
YU237190A true YU237190A (sh) 1994-11-15
YU47750B YU47750B (sh) 1996-01-08

Family

ID=23803077

Family Applications (1)

Application Number Title Priority Date Filing Date
YU237190A YU47750B (sh) 1989-12-20 1990-12-17 Aktivni fluorosupstituisani benzimidazoli i postupci za njihovo dobijanje

Country Status (22)

Country Link
US (1) US5049674A (sh)
EP (1) EP0506759A1 (sh)
JP (1) JPH05502448A (sh)
KR (1) KR927003573A (sh)
CN (1) CN1052670A (sh)
AU (1) AU641465B2 (sh)
CA (1) CA2070651A1 (sh)
EG (1) EG19360A (sh)
FI (1) FI922864A (sh)
HU (1) HUT61995A (sh)
IE (1) IE904248A1 (sh)
IL (1) IL96397A (sh)
IS (1) IS3658A7 (sh)
LT (1) LT3809B (sh)
LV (1) LV10952A (sh)
NO (1) NO922437L (sh)
NZ (1) NZ236102A (sh)
PL (1) PL167703B1 (sh)
PT (1) PT96256A (sh)
WO (1) WO1991009028A1 (sh)
YU (1) YU47750B (sh)
ZA (1) ZA909142B (sh)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU226778B1 (en) * 1992-07-28 2009-10-28 Astra Ab Injection and injection kit containing omeprazole and its analogs
GB9423970D0 (en) * 1994-11-28 1995-01-11 Astra Ab Oxidation
SE9600070D0 (sv) * 1996-01-08 1996-01-08 Astra Ab New oral pharmaceutical dosage forms

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US176308A (en) 1876-04-18 Improvement in buttons
SE418966B (sv) * 1974-02-18 1981-07-06 Haessle Ab Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan
SE416649B (sv) * 1974-05-16 1981-01-26 Haessle Ab Forfarande for framstellning av foreningar som paverkar magsyrasekretionen
IN148930B (sh) * 1977-09-19 1981-07-25 Hoffmann La Roche
SE7804231L (sv) * 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
US4359465A (en) * 1980-07-28 1982-11-16 The Upjohn Company Methods for treating gastrointestinal inflammation
CH644116A5 (de) * 1980-08-21 1984-07-13 Hoffmann La Roche Imidazolderivate.
SE8301182D0 (sv) * 1983-03-04 1983-03-04 Haessle Ab Novel compounds
IL71664A (en) * 1983-05-03 1987-11-30 Byk Gulden Lomberg Chem Fab Fluoroalkoxy compounds,process for their preparation and pharmaceutical compositions containing the same
JPS6150979A (ja) * 1984-08-16 1986-03-13 Takeda Chem Ind Ltd ピリジン誘導体およびその製造法
JPS6150978A (ja) * 1984-08-16 1986-03-13 Takeda Chem Ind Ltd ピリジン誘導体およびその製造法
AU568441B2 (en) * 1984-09-24 1987-12-24 Upjohn Company, The 2-(pyridylalkenesulfinyl) benzimidazole derivatives
US4738975A (en) * 1985-07-02 1988-04-19 Takeda Chemical Industries, Ltd. Pyridine derivatives, and use as anti-ulcer agents
SE8505112D0 (sv) * 1985-10-29 1985-10-29 Haessle Ab Novel pharmacological compounds
FI90544C (fi) * 1986-11-13 1994-02-25 Eisai Co Ltd Menetelmä lääkeaineina käyttökelpoisten 2-pyridin-2-yyli-metyylitio- ja sulfinyyli-1H-bensimidatsolijohdannaisten valmistamiseksi
NZ222495A (en) * 1986-11-21 1991-04-26 Haessle Ab Benzimidazole derivatives and pharmaceutical compositions
FI96860C (fi) * 1987-06-17 1996-09-10 Eisai Co Ltd Analogiamenetelmä lääkeaineena käytettävän pyridiinijohdannaisen valmistamiseksi
DE3722810A1 (de) * 1987-07-10 1989-01-19 Hoechst Ag Substituierte benzimidazole, verfahren zu deren herstellung, diese enthaltende pharmazeutische zubereitungen und deren verwendung
AU2817989A (en) * 1987-12-11 1989-07-05 Byk Gulden Lomberg Chemische Fabrik Gmbh Novel benzimidazole derivatives

Also Published As

Publication number Publication date
KR927003573A (ko) 1992-12-18
NO922437D0 (no) 1992-06-19
IL96397A0 (en) 1991-08-16
NO922437L (no) 1992-08-13
NZ236102A (en) 1992-12-23
PL288337A1 (en) 1991-12-02
HU9202071D0 (en) 1992-09-28
IL96397A (en) 1995-10-31
JPH05502448A (ja) 1993-04-28
AU641465B2 (en) 1993-09-23
FI922864A0 (fi) 1992-06-18
AU7038091A (en) 1991-07-18
LTIP1732A (en) 1995-08-25
US5049674A (en) 1991-09-17
CN1052670A (zh) 1991-07-03
LT3809B (en) 1996-03-25
EP0506759A1 (en) 1992-10-07
HUT61995A (en) 1993-03-29
YU47750B (sh) 1996-01-08
WO1991009028A1 (en) 1991-06-27
PT96256A (pt) 1991-09-30
LV10952A (lv) 1995-12-20
CA2070651A1 (en) 1991-06-21
IE904248A1 (en) 1991-07-03
IS3658A7 (is) 1991-06-21
EG19360A (en) 1994-12-30
PL167703B1 (en) 1995-10-31
FI922864A (fi) 1992-06-18
ZA909142B (en) 1991-08-28

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