LT3597189T - Kristaliniai junginia - Google Patents

Kristaliniai junginia

Info

Publication number
LT3597189T
LT3597189T LTEP19196556.5T LT19196556T LT3597189T LT 3597189 T LT3597189 T LT 3597189T LT 19196556 T LT19196556 T LT 19196556T LT 3597189 T LT3597189 T LT 3597189T
Authority
LT
Lithuania
Prior art keywords
crystalline compounds
crystalline
compounds
Prior art date
Application number
LTEP19196556.5T
Other languages
English (en)
Lithuanian (lt)
Inventor
Anthony Alexander Mckinney
Franklin Bymaster
Walter Piskorski
Fred J. Fleitz
Yonglai Yang
David A. Engers
Valeriya Smolenskaya
Venkat Kusukuntla
Original Assignee
Otsuka America Pharmaceutical, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka America Pharmaceutical, Inc. filed Critical Otsuka America Pharmaceutical, Inc.
Publication of LT3597189T publication Critical patent/LT3597189T/lt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/16Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of a saturated carbon skeleton containing rings other than six-membered aromatic rings
    • C07C211/17Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of a saturated carbon skeleton containing rings other than six-membered aromatic rings containing only non-condensed rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Epidemiology (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
LTEP19196556.5T 2015-06-17 2016-06-17 Kristaliniai junginia LT3597189T (lt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201562181174P 2015-06-17 2015-06-17

Publications (1)

Publication Number Publication Date
LT3597189T true LT3597189T (lt) 2022-07-11

Family

ID=57546597

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEP19196556.5T LT3597189T (lt) 2015-06-17 2016-06-17 Kristaliniai junginia

Country Status (25)

Country Link
US (5) US9708261B2 (https=)
EP (3) EP4049997A1 (https=)
JP (4) JP6896651B2 (https=)
KR (1) KR102593783B1 (https=)
CN (3) CN107921021A (https=)
AU (2) AU2016279075C1 (https=)
CA (2) CA3200692A1 (https=)
CY (1) CY1125352T1 (https=)
DK (1) DK3597189T3 (https=)
ES (1) ES2922158T3 (https=)
HK (1) HK1247125A1 (https=)
HR (1) HRP20220829T1 (https=)
HU (1) HUE059348T2 (https=)
LT (1) LT3597189T (https=)
MX (2) MX387591B (https=)
MY (1) MY194868A (https=)
NZ (2) NZ776973A (https=)
PH (1) PH12017502324A1 (https=)
PL (1) PL3597189T3 (https=)
PT (1) PT3597189T (https=)
SA (1) SA517390552B1 (https=)
SG (1) SG10201911417PA (https=)
SI (1) SI3597189T1 (https=)
TW (1) TWI751998B (https=)
WO (1) WO2016205762A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ592836A (en) 2005-07-27 2013-01-25 Dov Pharmaceutical Inc Novel 1-aryl-3-azabicyclo[3.1.0]hexanes: preparation and use to treat neuropsychiatric disorders
US20140206740A1 (en) 2011-07-30 2014-07-24 Neurovance, Inc. Use Of (1R,5S)-(+)-(Napthalen-2-yl)-3-Azabicyclo[3.1.0]Hexane In The Treatment Of Conditions Affected By Monoamine Neurotransmitters
KR20160101012A (ko) 2013-12-09 2016-08-24 뉴로반스, 인크. 신규 조성물
SG10201911417PA (en) 2015-06-17 2020-01-30 Otsuka America Pharmaceutical Inc Crystalline compounds
WO2019114394A1 (zh) * 2017-12-11 2019-06-20 苏州科睿思制药有限公司 Eb-1020的晶型及其制备方法和用途
JP7704681B2 (ja) * 2019-10-16 2025-07-08 大塚製薬株式会社 センタナファジンの製造方法
WO2022256215A1 (en) 2021-05-31 2022-12-08 Teva Pharmaceuticals International Gmbh Solid state form of centanafadine hcl and process for preparation thereof
US12502358B1 (en) 2024-08-13 2025-12-23 Innovate Therapeutics Llc Centanafadine multiphasic controlled-release pharmaceutical formulation

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL376604A1 (pl) 2002-11-08 2006-01-09 Dov Pharmaceuticals, Inc. Polimorfy chlorowodorku bicifadyny
PL1740593T3 (pl) 2004-04-19 2016-09-30 Sposoby wytwarzania wodorosiarczanu klopidogrelu w formie polimorficznej I
US20070043100A1 (en) 2005-08-16 2007-02-22 Hagen Eric J Novel polymorphs of azabicyclohexane
MX2007001827A (es) 2004-08-18 2007-04-23 Dov Pharmaceutical Inc Nuevas sustancias polimorfas de azabiciclohexano.
US20070082939A1 (en) 2005-07-26 2007-04-12 Lippa Arnold S Methods and compositions for the treatment of neuropathies and related disorders
NZ592836A (en) 2005-07-27 2013-01-25 Dov Pharmaceutical Inc Novel 1-aryl-3-azabicyclo[3.1.0]hexanes: preparation and use to treat neuropsychiatric disorders
US7919598B2 (en) 2006-06-28 2011-04-05 Bristol-Myers Squibb Company Crystal structures of SGLT2 inhibitors and processes for preparing same
US20080058535A1 (en) 2006-07-25 2008-03-06 Zhengming Chen Methods and compositions for production, formulation and use of 1 aryl-3-azabicyclo[3.1.0]hexanes
US8576985B2 (en) 2009-09-01 2013-11-05 Aptuit (West Lafayette) Llc Methods for indexing solid forms of compounds
CN103476770B (zh) * 2010-11-25 2017-02-15 拉蒂欧制药有限责任公司 阿法替尼盐和多晶型物
PT2819516T (pt) * 2011-07-30 2020-03-25 Otsuka America Pharmaceutical Inc Utilização de (1r,5s)-(+)-1-(naftalen-2-il)-3-azabiciclo[3.1.0]hexano no tratamento de doenças afectadas por neurotransmissores monoaminas
US20140206740A1 (en) * 2011-07-30 2014-07-24 Neurovance, Inc. Use Of (1R,5S)-(+)-(Napthalen-2-yl)-3-Azabicyclo[3.1.0]Hexane In The Treatment Of Conditions Affected By Monoamine Neurotransmitters
US20140228421A1 (en) 2011-09-07 2014-08-14 Anthony McKinney Methods For Inhibiting Native And Promiscuous Uptake Of Monoamine Neurotransmitters
KR20160101012A (ko) 2013-12-09 2016-08-24 뉴로반스, 인크. 신규 조성물
SG10201911417PA (en) 2015-06-17 2020-01-30 Otsuka America Pharmaceutical Inc Crystalline compounds

Also Published As

Publication number Publication date
US20170334850A1 (en) 2017-11-23
PT3597189T (pt) 2022-07-05
MX387591B (es) 2025-03-18
JP7244575B2 (ja) 2023-03-22
EP3310352A4 (en) 2019-03-13
KR20180014830A (ko) 2018-02-09
RU2018101244A (ru) 2019-07-22
JP2025022896A (ja) 2025-02-14
AU2016279075B2 (en) 2020-10-22
CY1125352T1 (el) 2025-05-09
US11299458B2 (en) 2022-04-12
KR102593783B1 (ko) 2023-10-25
EP3597189A1 (en) 2020-01-22
US20180194726A1 (en) 2018-07-12
NZ739044A (en) 2022-08-26
JP7583851B2 (ja) 2024-11-14
EP4049997A1 (en) 2022-08-31
JP2023071978A (ja) 2023-05-23
TWI751998B (zh) 2022-01-11
EP3597189B1 (en) 2022-06-01
AU2016279075A1 (en) 2018-02-01
CN117088802A (zh) 2023-11-21
US20160368871A1 (en) 2016-12-22
AU2021200314B2 (en) 2022-08-04
TW201800392A (zh) 2018-01-01
MX2017016430A (es) 2018-11-09
WO2016205762A1 (en) 2016-12-22
US9708261B2 (en) 2017-07-18
AU2021200314A1 (en) 2021-03-18
HRP20220829T1 (hr) 2022-12-23
PH12017502324A1 (en) 2018-06-25
SA517390552B1 (ar) 2022-04-13
JP2021138747A (ja) 2021-09-16
SI3597189T1 (sl) 2022-08-31
CA2989431C (en) 2023-08-29
SG10201911417PA (en) 2020-01-30
HUE059348T2 (hu) 2022-11-28
US10280141B2 (en) 2019-05-07
PL3597189T3 (pl) 2022-07-25
CA3200692A1 (en) 2016-12-22
JP6896651B2 (ja) 2021-06-30
JP2018517742A (ja) 2018-07-05
US10800740B2 (en) 2020-10-13
MX2020009949A (es) 2020-10-16
NZ776973A (en) 2022-11-25
HK1247125A1 (zh) 2018-09-21
CA2989431A1 (en) 2016-12-22
EP3310352A1 (en) 2018-04-25
DK3597189T3 (da) 2022-06-27
ES2922158T3 (es) 2022-09-09
RU2018101244A3 (https=) 2019-12-23
MY194868A (en) 2022-12-21
CN107921021A (zh) 2018-04-17
US9856217B2 (en) 2018-01-02
US20200039934A1 (en) 2020-02-06
CN117466800A (zh) 2024-01-30
US20210198198A1 (en) 2021-07-01
AU2016279075C1 (en) 2021-04-01

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