LT3436074T - Tiazolido junginiai, skirti virusinių infekcijų gydymui - Google Patents

Tiazolido junginiai, skirti virusinių infekcijų gydymui

Info

Publication number
LT3436074T
LT3436074T LTEP17716741.8T LT17716741T LT3436074T LT 3436074 T LT3436074 T LT 3436074T LT 17716741 T LT17716741 T LT 17716741T LT 3436074 T LT3436074 T LT 3436074T
Authority
LT
Lithuania
Prior art keywords
treatment
viral infections
thiazolide compounds
thiazolide
compounds
Prior art date
Application number
LTEP17716741.8T
Other languages
English (en)
Inventor
Jean-Francois Rossignol
Maria Gabriella Santoro
Original Assignee
Romark Laboratories, L.C.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Romark Laboratories, L.C. filed Critical Romark Laboratories, L.C.
Publication of LT3436074T publication Critical patent/LT3436074T/lt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/4261,3-Thiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
LTEP17716741.8T 2016-03-31 2017-03-30 Tiazolido junginiai, skirti virusinių infekcijų gydymui LT3436074T (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662316463P 2016-03-31 2016-03-31
PCT/US2017/024976 WO2017173056A1 (en) 2016-03-31 2017-03-30 Thiazolide compounds for treating viral infections

Publications (1)

Publication Number Publication Date
LT3436074T true LT3436074T (lt) 2020-09-25

Family

ID=58530692

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEP17716741.8T LT3436074T (lt) 2016-03-31 2017-03-30 Tiazolido junginiai, skirti virusinių infekcijų gydymui

Country Status (26)

Country Link
US (2) US11135202B2 (lt)
EP (2) EP3677282A1 (lt)
JP (2) JP6567781B2 (lt)
KR (3) KR102233826B1 (lt)
CN (1) CN108289961A (lt)
AU (2) AU2017244145B2 (lt)
BR (1) BR112018069974A2 (lt)
CA (2) CA3113354A1 (lt)
CY (1) CY1123221T1 (lt)
DK (1) DK3436074T3 (lt)
EA (2) EA202091849A1 (lt)
ES (1) ES2810303T3 (lt)
HK (1) HK1250945A1 (lt)
HR (1) HRP20201261T1 (lt)
HU (1) HUE050601T2 (lt)
IL (2) IL262018A (lt)
LT (1) LT3436074T (lt)
MX (2) MX381896B (lt)
PH (1) PH12018502058A1 (lt)
PL (1) PL3436074T3 (lt)
PT (1) PT3436074T (lt)
SG (1) SG11201808453UA (lt)
SI (1) SI3436074T1 (lt)
UA (1) UA126114C2 (lt)
WO (1) WO2017173056A1 (lt)
ZA (1) ZA201806644B (lt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111012778B (zh) * 2018-10-10 2022-06-24 北京市农林科学院 Nitazoxanide在抑制犬细小病毒中的应用
CN109536460A (zh) * 2018-12-07 2019-03-29 中国医学科学院医学生物学研究所 一种cv-a10病毒毒种及其人用灭活疫苗
CN110787161B (zh) * 2019-09-19 2022-09-27 中山大学 噻唑类化合物用于抗鱼类病毒的新用途
CN111012788B (zh) * 2019-12-12 2021-01-15 武汉职业技术学院 硝唑尼特和替唑尼特在制备抗猪繁殖与呼吸综合征病毒药物中的应用
JP2023537237A (ja) 2020-07-20 2023-08-31 ロマーク ラボラトリーズ,リミティド カンパニー チゾキサニドおよび2-ヒドロキシ-n-(5-クロロ-1,3-チアゾル-2-イル)ベンズアミド(rm-4848)とエタノールアミン、モルホリン、プロパノールアミン、ピペラジン、およびn-メチルピペラジンの結晶塩
WO2022046622A1 (en) 2020-08-24 2022-03-03 Romark Laboratories L.C. Use of thiazolides against coronaviruses
CA3219500A1 (en) * 2021-05-28 2022-12-01 Theodore HENDERSON Treatment using an antiviral compound and nitazoxanide
WO2023040990A1 (zh) 2021-09-15 2023-03-23 南京强新生物医药有限公司 治疗冠状病毒感染的新联用药物、药物组合物及其用途
CN114404439B (zh) * 2022-02-11 2023-07-11 山东农业大学 抑制不同类型猪繁殖与呼吸综合症病毒感染的阻断剂
CN116966178B (zh) * 2022-04-29 2025-10-03 成都贝诺科成生物科技有限公司 一种氨基硝基噻唑衍生物在制备预防和治疗病毒感染及其引起的相关疾病的药物中的用途
CN118161479B (zh) * 2024-03-12 2025-01-28 中国动物卫生与流行病学中心 银杏双黄酮在制备抗猪塞内卡病毒的制剂中的应用

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1437800A (en) 1973-08-08 1976-06-03 Phavic Sprl Derivatives of 2-benzamido-5-nitro-thiazoles
US5387598A (en) 1994-04-13 1995-02-07 Rossignol; Jean-Francois Composition and galenic formulation suitable for combatting affections of the lower abdomen
MX9604483A (es) 1994-09-08 1998-02-28 Jean-Francois Rossignol Derivados de benzamida, composiciones que contienen dicho derivado y uso de las mismas.
US5968961A (en) 1997-05-07 1999-10-19 Romark Laboratories, L.C. Pharmaceutical compositions of tizoxanide and nitazoxanide
US5965590A (en) 1994-09-08 1999-10-12 Romark Lab Lc Method for treatment of opportunistic infections with pharmaceutical compositions of tizoxanide and nitazoxanide
US5856348A (en) 1994-09-08 1999-01-05 Romark Laboratories, L.C. Method for treatment of trematodes with pharmaceutical compositions of tizoxanide and nitazoxanide
US5859038A (en) 1994-09-08 1999-01-12 Romark Laboratories, L.C. Method for treatment of helicobacter pylori infections
US5935591A (en) 1998-01-15 1999-08-10 Romark Laboratories, L.C. Method for treatment of equine protozoal myeloencephalitis with thiazolides
WO2004091519A2 (en) 2003-04-11 2004-10-28 Medimmune, Inc. Methods of preventing or treating respiratory conditions
UA90864C2 (en) 2004-09-09 2010-06-10 Ромарк Лебораториз, Л.К. Halogenated benzamide derivatives
US20060194853A1 (en) 2004-10-08 2006-08-31 Rossignol Jean F Alkyl benzamides
EP1871365A2 (en) * 2005-04-12 2008-01-02 Romark Laboratories, L.C. Methods for treating diseases through inhibition the function of molecular chaperones such as protein disulfide isomerases , pharmaceutical compositions comprising them, and screening methods for identifying therapeutic agents
AP2907A (en) 2006-01-09 2014-05-31 Romark Lab Lc Viral hepatitis treatment
ES2550755T3 (es) 2007-08-03 2015-11-12 Romark Laboratories, L.C. Compuestos de tiazolida sustituidos con alquilsulfonilo
GB0716292D0 (en) * 2007-08-21 2007-09-26 Biofocus Dpi Ltd Imidazopyrazine compounds
EP2395840B1 (en) 2009-02-13 2020-04-15 Romark Laboratories, L.C. Controlled release pharmaceutical formulations of nitazoxanide
CN105853415A (zh) * 2009-05-12 2016-08-17 罗马克实验室有限公司 卤代烷基杂芳基苯甲酰胺化合物
MX391013B (es) * 2009-06-26 2025-03-21 Romark Laboratories Lc Compuestos y metodos para tratar influenza.
WO2011160191A1 (en) * 2010-06-25 2011-12-29 Biota Scientific Management Pty Ltd Compound for the treatment of enteroviruses
EP2635124A4 (en) 2010-11-01 2014-04-16 Romark Lab Lc ALKYLSULFINYL-SUBSTITUTED THIAZOLIDE COMPOUNDS
KR102037162B1 (ko) 2011-05-16 2019-10-29 로마크 레버러토리즈, 엘.씨. 바이러스병, 암 및 세포내 감염으로 인한 질병의 예방 및 치료를 위한 티아졸리드 화합물의 용도
JP5904270B2 (ja) 2012-03-15 2016-04-13 トヨタ自動車株式会社 車両走行制御装置
AU2014331863C1 (en) * 2013-10-11 2019-05-16 Alios Biopharma, Inc. Substituted nucleosides, nucleotides and analogs thereof
US10328128B2 (en) * 2014-09-17 2019-06-25 Ansun Biopharma, Inc. Treatment of infection by human enterovirus D68
EP3217795A4 (en) 2014-11-11 2018-08-22 Romark Laboratories, L.C. Compositions and methods of treatment with prodrugs of tizoxanide, an analogue or salt thereof

Also Published As

Publication number Publication date
KR102136803B1 (ko) 2020-07-22
SG11201808453UA (en) 2018-10-30
EP3436074A1 (en) 2019-02-06
JP6567781B2 (ja) 2019-08-28
PT3436074T (pt) 2020-08-21
KR20210035339A (ko) 2021-03-31
MX381896B (es) 2025-03-13
EP3436074B1 (en) 2020-06-10
US20220125767A1 (en) 2022-04-28
KR102233826B1 (ko) 2021-03-31
MX2021004464A (es) 2021-06-04
IL280327A (en) 2021-03-01
WO2017173056A1 (en) 2017-10-05
CA3113354A1 (en) 2017-10-05
UA126114C2 (uk) 2022-08-17
BR112018069974A2 (pt) 2019-01-29
PH12018502058A1 (en) 2019-06-24
AU2017244145A1 (en) 2018-11-15
HRP20201261T1 (hr) 2021-02-05
CN108289961A (zh) 2018-07-17
EP3677282A1 (en) 2020-07-08
HUE050601T2 (hu) 2020-12-28
JP2019510044A (ja) 2019-04-11
AU2019236602A1 (en) 2019-10-17
US11135202B2 (en) 2021-10-05
CA3019326C (en) 2021-05-25
ES2810303T3 (es) 2021-03-08
CY1123221T1 (el) 2021-10-29
ZA201806644B (en) 2021-02-24
KR20180124970A (ko) 2018-11-21
EA036505B1 (ru) 2020-11-18
JP2019203014A (ja) 2019-11-28
CA3019326A1 (en) 2017-10-05
EA202091849A1 (ru) 2020-12-11
SI3436074T1 (sl) 2020-09-30
AU2017244145B2 (en) 2019-08-01
PL3436074T3 (pl) 2020-11-02
DK3436074T3 (da) 2020-08-03
EA201891975A1 (ru) 2019-03-29
HK1250945A1 (zh) 2019-01-18
KR20180125552A (ko) 2018-11-23
IL262018A (en) 2018-10-31
US20170281603A1 (en) 2017-10-05

Similar Documents

Publication Publication Date Title
IL263972A (en) Dihydropyranopyrimidines for the treatment of viral infections
IL280459A (en) Phosphoramidates for the treatment of hepatitis b virus
HUE058737T2 (hu) Eljárások arenaviridae vírusok okozta fertõzések kezelésére
LT3436074T (lt) Tiazolido junginiai, skirti virusinių infekcijų gydymui
HUE045137T2 (hu) HIV vírusfertõzés megelõzõ vagy terápiás kezelésére alkalmas terápiás vegyületek
IL253062A0 (en) Pyrazine compounds for the treatment of infectious diseases
LT3468965T (lt) 1-tetrahidropiranilkarbonil-2,3-dihidro-1h-indolo junginiai vėžio gydymui
HRP20181130T1 (hr) Postupci za liječenje infekcija virusom filoviridae
DK3474804T4 (da) Medicinsk forbinding
PL3681872T3 (pl) Podstawione heteroarylem beta-hydroksyetylaminy do stosowania w leczeniu hiperglikemii
HUE053191T2 (hu) 2-Heteroaril-3-oxo-2,3-dihidropiridazin-4-karboxamidok rák kezelésére
DK3511328T3 (da) Organiske monobactam-forbindelser til behandling af bakterieinfektioner
HRP20190580T1 (hr) Kombinirana terapija radi liječenja rezistentnih bakterijskih infekcija
HUE045906T2 (hu) Új szulfonimidoilpurinon vegyületek és származékok vírusfertõzés kezelésére és megelõzésére
LT3210973T (lt) Heteroarilo junginiai, skirti akių ligų gydymui
HUE060517T2 (hu) Immunhiányos betegség kezelésére szolgáló eljárások
PL3400269T3 (pl) Zastosowanie 4-bora-3a,4a-diaza-s-indacenów do zabezpieczania
LT3534885T (lt) Farneziltransferazės inhibitoriai, skirti naudoti vėžio gydymui
IL256327B (en) Pharmaceutical preparations for the treatment of viral problems of the eye
LT3113778T (lt) Piridazino dariniai, skirti naudoti ataksinio sutrikimo profilaktikai arba gydymui
DK3373931T3 (da) Heterocykliske forbindelser til behandling af sygdom
LT3273957T (lt) Biotinas, skirtas demielinizuojančių neuropatijų gydymui
KR20180084983A (ko) 암의 치료를 위한 피리미도-피리미다지논의 용도
DK3506956T3 (da) Lægemiddel, særlig til behandling af fistler
DK3471732T3 (da) Liposomer til behandling af virusinfektioner