SI3436074T1 - Tiazolidne spojine za zdravljenje virusnih infekcij - Google Patents

Tiazolidne spojine za zdravljenje virusnih infekcij

Info

Publication number
SI3436074T1
SI3436074T1 SI201730344T SI201730344T SI3436074T1 SI 3436074 T1 SI3436074 T1 SI 3436074T1 SI 201730344 T SI201730344 T SI 201730344T SI 201730344 T SI201730344 T SI 201730344T SI 3436074 T1 SI3436074 T1 SI 3436074T1
Authority
SI
Slovenia
Prior art keywords
viral infections
treating viral
thiazolide compounds
thiazolide
compounds
Prior art date
Application number
SI201730344T
Other languages
English (en)
Inventor
Jean-Francois Rossignol
Maria Gabriella Santoro
Original Assignee
Romark Laboratories, L.C.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Romark Laboratories, L.C. filed Critical Romark Laboratories, L.C.
Publication of SI3436074T1 publication Critical patent/SI3436074T1/sl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/4261,3-Thiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
SI201730344T 2016-03-31 2017-03-30 Tiazolidne spojine za zdravljenje virusnih infekcij SI3436074T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662316463P 2016-03-31 2016-03-31
EP17716741.8A EP3436074B1 (en) 2016-03-31 2017-03-30 Thiazolide compounds for treating viral infections
PCT/US2017/024976 WO2017173056A1 (en) 2016-03-31 2017-03-30 Thiazolide compounds for treating viral infections

Publications (1)

Publication Number Publication Date
SI3436074T1 true SI3436074T1 (sl) 2020-09-30

Family

ID=58530692

Family Applications (1)

Application Number Title Priority Date Filing Date
SI201730344T SI3436074T1 (sl) 2016-03-31 2017-03-30 Tiazolidne spojine za zdravljenje virusnih infekcij

Country Status (26)

Country Link
US (2) US11135202B2 (sl)
EP (2) EP3677282A1 (sl)
JP (2) JP6567781B2 (sl)
KR (3) KR102136803B1 (sl)
CN (1) CN108289961A (sl)
AU (2) AU2017244145B2 (sl)
BR (1) BR112018069974A2 (sl)
CA (2) CA3113354A1 (sl)
CY (1) CY1123221T1 (sl)
DK (1) DK3436074T3 (sl)
EA (2) EA036505B1 (sl)
ES (1) ES2810303T3 (sl)
HK (1) HK1250945A1 (sl)
HR (1) HRP20201261T1 (sl)
HU (1) HUE050601T2 (sl)
IL (2) IL262018A (sl)
LT (1) LT3436074T (sl)
MX (1) MX2021004464A (sl)
PH (1) PH12018502058A1 (sl)
PL (1) PL3436074T3 (sl)
PT (1) PT3436074T (sl)
SG (1) SG11201808453UA (sl)
SI (1) SI3436074T1 (sl)
UA (1) UA126114C2 (sl)
WO (1) WO2017173056A1 (sl)
ZA (1) ZA201806644B (sl)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111012778B (zh) * 2018-10-10 2022-06-24 北京市农林科学院 Nitazoxanide在抑制犬细小病毒中的应用
CN109536460A (zh) * 2018-12-07 2019-03-29 中国医学科学院医学生物学研究所 一种cv-a10病毒毒种及其人用灭活疫苗
CN110787161B (zh) * 2019-09-19 2022-09-27 中山大学 噻唑类化合物用于抗鱼类病毒的新用途
CN111012788B (zh) * 2019-12-12 2021-01-15 武汉职业技术学院 硝唑尼特和替唑尼特在制备抗猪繁殖与呼吸综合征病毒药物中的应用
JP2023537237A (ja) * 2020-07-20 2023-08-31 ロマーク ラボラトリーズ,リミティド カンパニー チゾキサニドおよび2-ヒドロキシ-n-(5-クロロ-1,3-チアゾル-2-イル)ベンズアミド(rm-4848)とエタノールアミン、モルホリン、プロパノールアミン、ピペラジン、およびn-メチルピペラジンの結晶塩
CN116367892A (zh) 2020-08-24 2023-06-30 罗马克实验室有限公司 噻唑化物抗冠状病毒的用途
CA3219500A1 (en) * 2021-05-28 2022-12-01 Theodore HENDERSON Treatment using an antiviral compound and nitazoxanide
TW202327621A (zh) 2021-09-15 2023-07-16 大陸商南京強新生物醫藥有限公司 治療冠狀病毒感染的新聯用藥物、藥物組合物及其用途
CN114404439B (zh) * 2022-02-11 2023-07-11 山东农业大学 抑制不同类型猪繁殖与呼吸综合症病毒感染的阻断剂
CN118161479A (zh) * 2024-03-12 2024-06-11 中国动物卫生与流行病学中心 银杏双黄酮在制备抗猪塞内卡病毒的制剂中的应用

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1437800A (en) 1973-08-08 1976-06-03 Phavic Sprl Derivatives of 2-benzamido-5-nitro-thiazoles
US5387598A (en) 1994-04-13 1995-02-07 Rossignol; Jean-Francois Composition and galenic formulation suitable for combatting affections of the lower abdomen
US5965590A (en) 1994-09-08 1999-10-12 Romark Lab Lc Method for treatment of opportunistic infections with pharmaceutical compositions of tizoxanide and nitazoxanide
US5859038A (en) 1994-09-08 1999-01-12 Romark Laboratories, L.C. Method for treatment of helicobacter pylori infections
MX9604483A (es) 1994-09-08 1998-02-28 Jean-Francois Rossignol Derivados de benzamida, composiciones que contienen dicho derivado y uso de las mismas.
US5856348A (en) 1994-09-08 1999-01-05 Romark Laboratories, L.C. Method for treatment of trematodes with pharmaceutical compositions of tizoxanide and nitazoxanide
US5968961A (en) 1997-05-07 1999-10-19 Romark Laboratories, L.C. Pharmaceutical compositions of tizoxanide and nitazoxanide
US5935591A (en) 1998-01-15 1999-08-10 Romark Laboratories, L.C. Method for treatment of equine protozoal myeloencephalitis with thiazolides
US7582297B2 (en) 2003-04-11 2009-09-01 Medimmune, Llc Methods of treating respiratory conditions
UA90864C2 (en) * 2004-09-09 2010-06-10 Ромарк Лебораториз, Л.К. Halogenated benzamide derivatives
US20060194853A1 (en) 2004-10-08 2006-08-31 Rossignol Jean F Alkyl benzamides
JP2008538362A (ja) * 2005-04-12 2008-10-23 ロマーク ラボラトリーズ エル.シー. タンパク質の成熟の遮断を介して疾患を処置するための方法、タンパク質ジスルフィドイソメラーゼなどの分子シャペロンの機能を阻害する、またはグリコシル化を妨害する化合物、それらを含む薬学的組成物、および治療剤を同定するためのスクリーニング方法
ES2422556T3 (es) 2006-01-09 2013-09-12 Romark Lab Lc Tratamiento de hepatitis vírica
BRPI0815057B8 (pt) 2007-08-03 2021-05-25 Romark Laboratories Lc composto, composição farmacêutica, e, uso de um composto
GB0716292D0 (en) * 2007-08-21 2007-09-26 Biofocus Dpi Ltd Imidazopyrazine compounds
CA2752233C (en) 2009-02-13 2017-01-03 Romark Laboratories L.C. Controlled release pharmaceutical formulations of nitazoxanide
JP5918124B2 (ja) 2009-05-12 2016-05-18 ロマーク ラボラトリーズ エル.シー. ハロアルキルヘテロアリールベンズアミド化合物
BRPI1014322A2 (pt) * 2009-06-26 2015-08-25 Romark Lab Lc Método para tratar infecção, e para interromper ou evitar a produção de partículas virais infecciosas, combinação, e, composição farmacêutica.
EP2585067B1 (en) * 2010-06-25 2017-08-09 Biota Scientific Management Pty Ltd Compound for the treatment of enteroviruses
EP2635124A4 (en) 2010-11-01 2014-04-16 Romark Lab Lc ALKYLSULFINYL-SUBSTITUTED THIAZOLIDE COMPOUNDS
CA2836253C (en) 2011-05-16 2021-02-16 Romark Laboratories, L.C. Use of thiazolide compounds for the prevention and treatment of viral diseases, cancer and diseases caused by intracellular infections
WO2013136495A1 (ja) 2012-03-15 2013-09-19 トヨタ自動車株式会社 車両走行制御装置
SG10201804835VA (en) * 2013-10-11 2018-07-30 Alios Biopharma Inc Substituted nucleosides, nucleotides and analogs thereof
WO2016044656A1 (en) * 2014-09-17 2016-03-24 Ansun Biopharma, Inc. Treatment of infection by human enterovirus d68
BR112017009651A2 (pt) 2014-11-11 2017-12-19 Romark Laboratories Lc composto, composição farmacêutica, e, método para tratamento de uma infecção por protozoário intracelular, uma infecção viral ou um câncer.

Also Published As

Publication number Publication date
ES2810303T3 (es) 2021-03-08
EP3436074B1 (en) 2020-06-10
HRP20201261T1 (hr) 2021-02-05
HK1250945A1 (zh) 2019-01-18
IL280327A (en) 2021-03-01
JP2019203014A (ja) 2019-11-28
UA126114C2 (uk) 2022-08-17
US20170281603A1 (en) 2017-10-05
US20220125767A1 (en) 2022-04-28
IL262018A (en) 2018-10-31
KR102136803B1 (ko) 2020-07-22
AU2017244145A1 (en) 2018-11-15
CN108289961A (zh) 2018-07-17
EA036505B1 (ru) 2020-11-18
KR20180125552A (ko) 2018-11-23
PH12018502058A1 (en) 2019-06-24
MX2021004464A (es) 2021-06-04
HUE050601T2 (hu) 2020-12-28
JP2019510044A (ja) 2019-04-11
LT3436074T (lt) 2020-09-25
CA3113354A1 (en) 2017-10-05
AU2017244145B2 (en) 2019-08-01
ZA201806644B (en) 2021-02-24
WO2017173056A1 (en) 2017-10-05
CA3019326A1 (en) 2017-10-05
KR20210035339A (ko) 2021-03-31
US11135202B2 (en) 2021-10-05
CY1123221T1 (el) 2021-10-29
PL3436074T3 (pl) 2020-11-02
PT3436074T (pt) 2020-08-21
CA3019326C (en) 2021-05-25
DK3436074T3 (da) 2020-08-03
EP3436074A1 (en) 2019-02-06
KR102233826B1 (ko) 2021-03-31
EP3677282A1 (en) 2020-07-08
EA202091849A1 (ru) 2020-12-11
BR112018069974A2 (pt) 2019-01-29
SG11201808453UA (en) 2018-10-30
KR20180124970A (ko) 2018-11-21
AU2019236602A1 (en) 2019-10-17
EA201891975A1 (ru) 2019-03-29
JP6567781B2 (ja) 2019-08-28

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