SG11201808453UA - Thiazolide compounds for treating viral infections - Google Patents

Thiazolide compounds for treating viral infections

Info

Publication number
SG11201808453UA
SG11201808453UA SG11201808453UA SG11201808453UA SG11201808453UA SG 11201808453U A SG11201808453U A SG 11201808453UA SG 11201808453U A SG11201808453U A SG 11201808453UA SG 11201808453U A SG11201808453U A SG 11201808453UA SG 11201808453U A SG11201808453U A SG 11201808453UA
Authority
SG
Singapore
Prior art keywords
viral infections
treating viral
thiazolide compounds
thiazolide
compounds
Prior art date
Application number
SG11201808453UA
Inventor
Jean-Francois Rossignol
Maria Gabriella Santoro
Original Assignee
Romark Laboratories Lc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Romark Laboratories Lc filed Critical Romark Laboratories Lc
Publication of SG11201808453UA publication Critical patent/SG11201808453UA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/4261,3-Thiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
SG11201808453UA 2016-03-31 2017-03-30 Thiazolide compounds for treating viral infections SG11201808453UA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662316463P 2016-03-31 2016-03-31
PCT/US2017/024976 WO2017173056A1 (en) 2016-03-31 2017-03-30 Thiazolide compounds for treating viral infections

Publications (1)

Publication Number Publication Date
SG11201808453UA true SG11201808453UA (en) 2018-10-30

Family

ID=58530692

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201808453UA SG11201808453UA (en) 2016-03-31 2017-03-30 Thiazolide compounds for treating viral infections

Country Status (26)

Country Link
US (2) US11135202B2 (en)
EP (2) EP3436074B1 (en)
JP (2) JP6567781B2 (en)
KR (3) KR20210035339A (en)
CN (1) CN108289961A (en)
AU (2) AU2017244145B2 (en)
BR (1) BR112018069974A2 (en)
CA (2) CA3113354A1 (en)
CY (1) CY1123221T1 (en)
DK (1) DK3436074T3 (en)
EA (2) EA036505B1 (en)
ES (1) ES2810303T3 (en)
HK (1) HK1250945A1 (en)
HR (1) HRP20201261T1 (en)
HU (1) HUE050601T2 (en)
IL (2) IL262018A (en)
LT (1) LT3436074T (en)
MX (1) MX2021004464A (en)
PH (1) PH12018502058A1 (en)
PL (1) PL3436074T3 (en)
PT (1) PT3436074T (en)
SG (1) SG11201808453UA (en)
SI (1) SI3436074T1 (en)
UA (1) UA126114C2 (en)
WO (1) WO2017173056A1 (en)
ZA (1) ZA201806644B (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111012778B (en) * 2018-10-10 2022-06-24 北京市农林科学院 Application of Nitazoxanide in inhibiting canine parvovirus
CN109536460A (en) * 2018-12-07 2019-03-29 中国医学科学院医学生物学研究所 A kind of CV-A10 virus seed culture of viruses and its inactivated vaccine for human
CN110787161B (en) * 2019-09-19 2022-09-27 中山大学 New application of thiazole compound in resisting fish virus
CN111012788B (en) * 2019-12-12 2021-01-15 武汉职业技术学院 Application of nitazoxanide and tizoxanide in preparation of medicine for resisting porcine reproductive and respiratory syndrome virus
WO2022020243A1 (en) * 2020-07-20 2022-01-27 Romark Laboratories L.C. Crystalline salts of tizoxanide and 2-hydroxy-n-(5-chloro-1,3-thiazol-2-yl)benzamide (rm-4848) with ethanolamine, morpholine, propanolamine, piperazine and n-methylpiperazine
JP2023538136A (en) 2020-08-24 2023-09-06 ロマーク ラボラトリーズ,リミティド カンパニー Use of thiazolides against coronavirus
CA3219500A1 (en) * 2021-05-28 2022-12-01 Theodore HENDERSON Treatment using an antiviral compound and nitazoxanide
JP2024533532A (en) 2021-09-15 2024-09-12 ワングローブ ホールディングス リミテッド Novel drug combinations, pharmaceutical compositions and uses thereof for treating coronavirus infections
CN114404439B (en) * 2022-02-11 2023-07-11 山东农业大学 Blocking agent for inhibiting different types of porcine reproductive and respiratory syndrome virus infection
CN118161479A (en) * 2024-03-12 2024-06-11 中国动物卫生与流行病学中心 Application of ginkgo biflavone in preparation of preparation for resisting porcine saikavirus

Family Cites Families (25)

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GB1437800A (en) 1973-08-08 1976-06-03 Phavic Sprl Derivatives of 2-benzamido-5-nitro-thiazoles
US5387598A (en) 1994-04-13 1995-02-07 Rossignol; Jean-Francois Composition and galenic formulation suitable for combatting affections of the lower abdomen
US5968961A (en) 1997-05-07 1999-10-19 Romark Laboratories, L.C. Pharmaceutical compositions of tizoxanide and nitazoxanide
US5859038A (en) 1994-09-08 1999-01-12 Romark Laboratories, L.C. Method for treatment of helicobacter pylori infections
MX9604483A (en) 1994-09-08 1998-02-28 Jean-Francois Rossignol Benzamide derivative, compositions containing said derivative and use thereof.
US5965590A (en) 1994-09-08 1999-10-12 Romark Lab Lc Method for treatment of opportunistic infections with pharmaceutical compositions of tizoxanide and nitazoxanide
US5856348A (en) 1994-09-08 1999-01-05 Romark Laboratories, L.C. Method for treatment of trematodes with pharmaceutical compositions of tizoxanide and nitazoxanide
US5935591A (en) 1998-01-15 1999-08-10 Romark Laboratories, L.C. Method for treatment of equine protozoal myeloencephalitis with thiazolides
US7582297B2 (en) 2003-04-11 2009-09-01 Medimmune, Llc Methods of treating respiratory conditions
UA90864C2 (en) 2004-09-09 2010-06-10 Ромарк Лебораториз, Л.К. Halogenated benzamide derivatives
US20060194853A1 (en) 2004-10-08 2006-08-31 Rossignol Jean F Alkyl benzamides
AU2006235490A1 (en) * 2005-04-12 2006-10-19 Romark Laboratories, L.C. Methods for treating diseases through the function of molecular chaperones such as protein disulfide isomerases, pharmaceutical compositions comprising them, and screening methods for identifying therapeutic agents
BRPI0706379A2 (en) 2006-01-09 2011-03-22 Romark Lab Lc viral hepatitis treatment
CN101835765B (en) 2007-08-03 2013-05-29 罗马克实验室有限公司 Alkylsulfonyl-substituted thiazolide compounds
GB0716292D0 (en) * 2007-08-21 2007-09-26 Biofocus Dpi Ltd Imidazopyrazine compounds
AU2010213678B2 (en) 2009-02-13 2015-11-26 Romark Laboratories L.C. Controlled release pharmaceutical formulations of nitazoxanide
NZ596538A (en) 2009-05-12 2014-04-30 Romark Lab Lc Haloalkyl heteroaryl benzamide compounds
CN108042535A (en) * 2009-06-26 2018-05-18 罗马克实验室有限公司 For treating the Compounds and methods for of influenza
WO2011160191A1 (en) * 2010-06-25 2011-12-29 Biota Scientific Management Pty Ltd Compound for the treatment of enteroviruses
WO2012061190A1 (en) 2010-11-01 2012-05-10 Romark Laboratories L.C. Alkylsulfinyl-substituted thiazolide compounds
KR102037162B1 (en) 2011-05-16 2019-10-29 로마크 레버러토리즈, 엘.씨. Use of thiazolide compounds for the prevention and treatment of viral diseases, cancer and diseases caused by intracellular infections
JP5904270B2 (en) 2012-03-15 2016-04-13 トヨタ自動車株式会社 Vehicle travel control device
SG10201804835VA (en) * 2013-10-11 2018-07-30 Alios Biopharma Inc Substituted nucleosides, nucleotides and analogs thereof
WO2016044656A1 (en) * 2014-09-17 2016-03-24 Ansun Biopharma, Inc. Treatment of infection by human enterovirus d68
CN107105660A (en) 2014-11-11 2017-08-29 罗马克实验室有限公司 Use the therapeutic combination and treatment method of the prodrug of tizoxanide, its analog or salt

Also Published As

Publication number Publication date
CN108289961A (en) 2018-07-17
JP6567781B2 (en) 2019-08-28
IL262018A (en) 2018-10-31
WO2017173056A1 (en) 2017-10-05
UA126114C2 (en) 2022-08-17
BR112018069974A2 (en) 2019-01-29
PT3436074T (en) 2020-08-21
SI3436074T1 (en) 2020-09-30
US20220125767A1 (en) 2022-04-28
KR20210035339A (en) 2021-03-31
CY1123221T1 (en) 2021-10-29
ES2810303T3 (en) 2021-03-08
DK3436074T3 (en) 2020-08-03
HRP20201261T1 (en) 2021-02-05
ZA201806644B (en) 2021-02-24
KR102233826B1 (en) 2021-03-31
AU2019236602A1 (en) 2019-10-17
CA3113354A1 (en) 2017-10-05
HK1250945A1 (en) 2019-01-18
EA201891975A1 (en) 2019-03-29
CA3019326C (en) 2021-05-25
EP3436074A1 (en) 2019-02-06
PL3436074T3 (en) 2020-11-02
MX2021004464A (en) 2021-06-04
AU2017244145B2 (en) 2019-08-01
US20170281603A1 (en) 2017-10-05
EP3677282A1 (en) 2020-07-08
KR20180124970A (en) 2018-11-21
CA3019326A1 (en) 2017-10-05
JP2019203014A (en) 2019-11-28
PH12018502058A1 (en) 2019-06-24
EA036505B1 (en) 2020-11-18
LT3436074T (en) 2020-09-25
EP3436074B1 (en) 2020-06-10
HUE050601T2 (en) 2020-12-28
AU2017244145A1 (en) 2018-11-15
IL280327A (en) 2021-03-01
KR20180125552A (en) 2018-11-23
KR102136803B1 (en) 2020-07-22
EA202091849A1 (en) 2020-12-11
US11135202B2 (en) 2021-10-05
JP2019510044A (en) 2019-04-11

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