LT3250230T - Komplemento aktyvumo moduliatoriai - Google Patents

Komplemento aktyvumo moduliatoriai

Info

Publication number
LT3250230T
LT3250230T LTEPPCT/US2016/015412T LT16015412T LT3250230T LT 3250230 T LT3250230 T LT 3250230T LT 16015412 T LT16015412 T LT 16015412T LT 3250230 T LT3250230 T LT 3250230T
Authority
LT
Lithuania
Prior art keywords
modulators
complement activity
complement
activity
Prior art date
Application number
LTEPPCT/US2016/015412T
Other languages
English (en)
Lithuanian (lt)
Inventor
Michelle HOARTY
Ketki DHAMNASKAR
Daniel Elbaum
Kristopher JOSEPHSON
Kelley LARSON
Zhong MA
Nathan NIMS
Alonso RICARDO
Kathleen Seyb
Guo-Qing Tang
Douglas Treco
Zhaolin Wang
Ping Ye
Hong Zheng
Sarah PERLMUTTER
Original Assignee
Ra Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2015/035473 external-priority patent/WO2015191951A2/en
Application filed by Ra Pharmaceuticals, Inc. filed Critical Ra Pharmaceuticals, Inc.
Publication of LT3250230T publication Critical patent/LT3250230T/lt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/36—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood coagulation factors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Transplantation (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Amplifiers (AREA)
  • Oscillators With Electromechanical Resonators (AREA)
LTEPPCT/US2016/015412T 2015-01-28 2016-01-28 Komplemento aktyvumo moduliatoriai LT3250230T (lt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201562108772P 2015-01-28 2015-01-28
PCT/US2015/035473 WO2015191951A2 (en) 2014-06-12 2015-06-12 Modulation of complement activity
US201562185298P 2015-06-26 2015-06-26
PCT/US2016/015412 WO2016123371A1 (en) 2015-01-28 2016-01-28 Modulators of complement activity

Publications (1)

Publication Number Publication Date
LT3250230T true LT3250230T (lt) 2021-12-27

Family

ID=56544343

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEPPCT/US2016/015412T LT3250230T (lt) 2015-01-28 2016-01-28 Komplemento aktyvumo moduliatoriai

Country Status (14)

Country Link
US (6) US9937222B2 (cg-RX-API-DMAC10.html)
EP (2) EP3250230B9 (cg-RX-API-DMAC10.html)
JP (2) JP6640229B2 (cg-RX-API-DMAC10.html)
CY (1) CY1124761T1 (cg-RX-API-DMAC10.html)
ES (1) ES2900998T3 (cg-RX-API-DMAC10.html)
HR (1) HRP20211824T1 (cg-RX-API-DMAC10.html)
HU (1) HUE056613T2 (cg-RX-API-DMAC10.html)
LT (1) LT3250230T (cg-RX-API-DMAC10.html)
PL (1) PL3250230T3 (cg-RX-API-DMAC10.html)
PT (1) PT3250230T (cg-RX-API-DMAC10.html)
RS (1) RS62630B9 (cg-RX-API-DMAC10.html)
SI (1) SI3250230T1 (cg-RX-API-DMAC10.html)
SM (1) SMT202100688T1 (cg-RX-API-DMAC10.html)
WO (1) WO2016123371A1 (cg-RX-API-DMAC10.html)

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KR20260070290A (ko) * 2015-12-16 2026-05-18 유씨비 홀딩스 인코포레이티드 보체 활성의 조절인자
JP7301741B2 (ja) * 2016-12-07 2023-07-03 ラ ファーマシューティカルズ インコーポレイテッド 補体活性のモジュレータ
CN110831617A (zh) * 2017-04-21 2020-02-21 沃卢申伊缪诺制药公司 用于治疗瘢痕性眼部发炎性病症的Coversin
JP7209637B2 (ja) 2017-04-21 2023-01-20 ヴォリューション イミュノ ファーマシューティカルズ エスエイ 自己免疫性水疱症の治療のためのコバーシン
SG11202103972SA (en) 2018-10-22 2021-05-28 Ra Pharmaceuticals Inc Neurological disease treatment with zilucoplan
ES2973767T3 (es) 2019-06-04 2024-06-24 Ra Pharmaceuticals Inc Tratamiento de enfermedades inflamatorias con inhibidores del complemento
JP6773930B1 (ja) 2019-08-09 2020-10-21 住友化学株式会社 液晶ポリエステル樹脂成形体、液晶ポリエステル樹脂ペレット、及び液晶ポリエステル樹脂ペレットの製造方法
CA3150594A1 (en) 2019-09-12 2021-03-18 Ra Pharmaceuticals, Inc. Neurological disease treatment with complement inhibitors
WO2022177635A2 (en) * 2021-02-22 2022-08-25 Ra Pharmaceuticals, Inc. Compositions and methods for microbial disease treatment
CN122255228A (zh) * 2024-12-20 2026-06-23 重庆派金生物科技有限公司 靶向抑制c3与c5补体的双功能多肽、多肽偶联物及它们的应用

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Also Published As

Publication number Publication date
US20180193408A1 (en) 2018-07-12
HRP20211824T1 (hr) 2022-03-04
US20180021402A1 (en) 2018-01-25
ES2900998T3 (es) 2022-03-21
US10918691B2 (en) 2021-02-16
US20190307835A1 (en) 2019-10-10
US20200155639A1 (en) 2020-05-21
CY1124761T1 (el) 2022-11-25
PT3250230T (pt) 2021-12-07
US10328115B2 (en) 2019-06-25
HK1246672A1 (zh) 2018-09-14
US20210283212A1 (en) 2021-09-16
HUE056613T2 (hu) 2022-02-28
SMT202100688T1 (it) 2022-01-10
US12239684B2 (en) 2025-03-04
EP3250230B9 (en) 2022-02-23
JP6640229B2 (ja) 2020-02-05
US10588936B2 (en) 2020-03-17
EP3250230B1 (en) 2021-11-10
EP3988110A1 (en) 2022-04-27
PL3250230T3 (pl) 2022-02-14
EP3250230A1 (en) 2017-12-06
RS62630B1 (sr) 2021-12-31
US11707503B2 (en) 2023-07-25
JP6915034B2 (ja) 2021-08-04
SI3250230T1 (sl) 2022-01-31
US9937222B2 (en) 2018-04-10
US20240156896A1 (en) 2024-05-16
JP2018509388A (ja) 2018-04-05
RS62630B9 (sr) 2022-04-29
JP2020073526A (ja) 2020-05-14
EP3250230A4 (en) 2019-01-23
WO2016123371A1 (en) 2016-08-04

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