LT2890699T - Kristalinės 1-(5'-(5-(3,5-dichlor-4-fluorfenil)-5-(trifluormetil)-4,5-dihidroizoksazol-3-il)-3'h-spiro[azetidin-3,1'-izobenzofuran]-1-il)-2-(metilsulfonil)etano formos - Google Patents
Kristalinės 1-(5'-(5-(3,5-dichlor-4-fluorfenil)-5-(trifluormetil)-4,5-dihidroizoksazol-3-il)-3'h-spiro[azetidin-3,1'-izobenzofuran]-1-il)-2-(metilsulfonil)etano formosInfo
- Publication number
- LT2890699T LT2890699T LTEP13756985.1T LT13756985T LT2890699T LT 2890699 T LT2890699 T LT 2890699T LT 13756985 T LT13756985 T LT 13756985T LT 2890699 T LT2890699 T LT 2890699T
- Authority
- LT
- Lithuania
- Prior art keywords
- dihydroisoxazol
- isobenzofuran
- azetidine
- ethanone
- methylsulfonyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- C07D491/107—Spiro-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/14—Ectoparasiticides, e.g. scabicides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261695410P | 2012-08-31 | 2012-08-31 | |
| PCT/US2013/056945 WO2014036056A1 (en) | 2012-08-31 | 2013-08-28 | Crystalline forms of 1-(5'-(5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-3'h-spiro[azetidine-3,1'-isobenzofuran]-1-yl)-2-(methylsulfonyl)ethanone |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| LT2890699T true LT2890699T (lt) | 2018-06-25 |
Family
ID=49115603
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| LTEP13756985.1T LT2890699T (lt) | 2012-08-31 | 2013-08-28 | Kristalinės 1-(5'-(5-(3,5-dichlor-4-fluorfenil)-5-(trifluormetil)-4,5-dihidroizoksazol-3-il)-3'h-spiro[azetidin-3,1'-izobenzofuran]-1-il)-2-(metilsulfonil)etano formos |
Country Status (29)
| Country | Link |
|---|---|
| US (1) | US9200003B2 (lt) |
| EP (1) | EP2890699B1 (lt) |
| JP (1) | JP6109942B2 (lt) |
| KR (1) | KR101736643B1 (lt) |
| CN (1) | CN104812758B (lt) |
| AR (1) | AR092409A1 (lt) |
| AU (1) | AU2013308887B2 (lt) |
| BR (1) | BR112015004135B8 (lt) |
| CA (1) | CA2881467C (lt) |
| CL (1) | CL2015000332A1 (lt) |
| CY (1) | CY1120611T1 (lt) |
| DK (1) | DK2890699T3 (lt) |
| ES (1) | ES2671271T3 (lt) |
| HK (1) | HK1209125A1 (lt) |
| HR (1) | HRP20180861T1 (lt) |
| HU (1) | HUE037667T2 (lt) |
| LT (1) | LT2890699T (lt) |
| MX (1) | MX351463B (lt) |
| NO (1) | NO2931268T3 (lt) |
| NZ (1) | NZ704175A (lt) |
| PH (1) | PH12015500441B1 (lt) |
| PL (1) | PL2890699T3 (lt) |
| PT (1) | PT2890699T (lt) |
| RS (1) | RS57284B1 (lt) |
| RU (1) | RU2614978C2 (lt) |
| SI (1) | SI2890699T1 (lt) |
| TR (1) | TR201807735T4 (lt) |
| WO (1) | WO2014036056A1 (lt) |
| ZA (1) | ZA201500728B (lt) |
Families Citing this family (68)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ704627A (en) | 2012-09-07 | 2016-01-29 | Zoetis Services Llc | Spirocyclic isoxazoline parasiticidal combinations |
| AU2013312896A1 (en) * | 2012-09-07 | 2015-02-26 | Zoetis Services Llc | Spirocyclic derivatives as antiparasitic agents |
| AR096346A1 (es) * | 2013-05-20 | 2015-12-23 | Zoetis Llc | Composiciones antiparasitarias de espiro-isoxazolina de acción prolongada |
| EP3204390B1 (en) | 2014-10-06 | 2019-06-05 | Basf Se | Substituted pyrimidinium compounds for combating animal pests |
| US20180368404A1 (en) | 2014-11-06 | 2018-12-27 | Basf Se | 3-pyridyl heterobicyclic compound for controlling invertebrate pests |
| US11064696B2 (en) | 2015-04-07 | 2021-07-20 | Basf Agrochemical Products B.V. | Use of an insecticidal carboxamide compound against pests on cultivated plants |
| WO2016198613A1 (en) | 2015-06-11 | 2016-12-15 | Basf Se | N-(thio)acylimino compounds |
| WO2016198611A1 (en) | 2015-06-11 | 2016-12-15 | Basf Se | N-(thio)acylimino heterocyclic compounds |
| WO2017016883A1 (en) | 2015-07-24 | 2017-02-02 | Basf Se | Process for preparation of cyclopentene compounds |
| EP3356341B1 (en) | 2015-10-02 | 2020-04-01 | Basf Se | Imino compounds with a 2-chloropyrimidin-5-yl substituent as pest-control agents |
| CA3003956A1 (en) | 2015-11-30 | 2017-06-08 | Basf Se | Mixtures of cis-jasmone and bacillus amyloliquefaciens |
| US20190077809A1 (en) | 2016-03-09 | 2019-03-14 | Basf Se | Spirocyclic Derivatives |
| CN108697089A (zh) | 2016-03-11 | 2018-10-23 | 巴斯夫欧洲公司 | 防除植物害虫的方法 |
| BR112018068851B1 (pt) | 2016-04-01 | 2022-11-22 | Basf Se | Composto de fórmula i, composição, métodos de combate ou controle de pragas invertebradas e de proteção de plantas, semente revestida e uso de pelo menos um composto |
| WO2018082962A1 (en) * | 2016-11-02 | 2018-05-11 | Basf Se | Process for preparation of tetrahydrothiophene derivatives |
| MX2019007120A (es) | 2016-12-16 | 2019-09-16 | Basf Se | Compuestos plaguicidas. |
| WO2018162312A1 (en) | 2017-03-10 | 2018-09-13 | Basf Se | Spirocyclic derivatives |
| WO2018166855A1 (en) | 2017-03-16 | 2018-09-20 | Basf Se | Heterobicyclic substituted dihydroisoxazoles |
| MX2019011626A (es) | 2017-03-28 | 2019-12-05 | Basf Se | Compuestos plaguicidas. |
| CN116102580A (zh) | 2017-03-31 | 2023-05-12 | 巴斯夫欧洲公司 | 用于防除动物害虫的嘧啶鎓化合物及其混合物 |
| WO2018192793A1 (en) | 2017-04-20 | 2018-10-25 | Basf Se | Substituted rhodanine derivatives |
| RU2019136972A (ru) | 2017-04-26 | 2021-05-26 | Басф Се | Замещенные сукцинимидные производные в качестве пестицидов |
| IL270403B (en) | 2017-05-10 | 2022-06-01 | Basf Se | Cyclical pesticidal compounds |
| WO2018224455A1 (en) | 2017-06-07 | 2018-12-13 | Basf Se | Substituted cyclopropyl derivatives |
| WO2018229202A1 (en) | 2017-06-16 | 2018-12-20 | Basf Se | Mesoionic imidazolium compounds and derivatives for combating animal pests |
| CN110678469B (zh) | 2017-06-19 | 2023-03-03 | 巴斯夫欧洲公司 | 用于防除动物害虫的取代嘧啶鎓化合物和衍生物 |
| WO2018234488A1 (en) | 2017-06-23 | 2018-12-27 | Basf Se | SUBSTITUTED CYCLOPROPYL DERIVATIVES |
| WO2019042932A1 (en) | 2017-08-31 | 2019-03-07 | Basf Se | METHOD FOR CONTROLLING RICE PARASITES IN RICE |
| EP3453706A1 (en) | 2017-09-08 | 2019-03-13 | Basf Se | Pesticidal imidazole compounds |
| EP3694852A1 (en) | 2017-10-13 | 2020-08-19 | Basf Se | Imidazolidine pyrimidinium compounds for combating animal pests |
| WO2019099669A1 (en) * | 2017-11-16 | 2019-05-23 | Avista Pharma Solutions, Inc. | Single enantiomer antiparasitic compounds |
| BR112020012018A2 (pt) | 2017-12-15 | 2020-11-24 | Tarsus Pharmaceuticals, Inc. | formulações de parasiticida de isoxazolina e métodos para tratar blefarite |
| WO2019121143A1 (en) | 2017-12-20 | 2019-06-27 | Basf Se | Substituted cyclopropyl derivatives |
| MX2020006566A (es) | 2017-12-21 | 2020-09-25 | Basf Se | Compuestos plaguicidas. |
| AU2019211978A1 (en) | 2018-01-09 | 2020-07-09 | Basf Se | Silylethynyl hetaryl compounds as nitrification inhibitors |
| WO2019137995A1 (en) | 2018-01-11 | 2019-07-18 | Basf Se | Novel pyridazine compounds for controlling invertebrate pests |
| EP3758491A1 (en) | 2018-02-28 | 2021-01-06 | Basf Se | Use of pyrazole propargyl ethers as nitrification inhibitors |
| MX2020009022A (es) | 2018-02-28 | 2020-10-12 | Basf Se | Uso de alcoxipirazoles como inhibidores de la nitrificacion. |
| US11578012B2 (en) | 2018-02-28 | 2023-02-14 | Basf Se | Use of N-functionalized alkoxy pyrazole compounds as nitrification inhibitors |
| WO2019175713A1 (en) | 2018-03-14 | 2019-09-19 | Basf Corporation | New catechol molecules and their use as inhibitors to p450 related metabolic pathways |
| WO2019175712A1 (en) | 2018-03-14 | 2019-09-19 | Basf Corporation | New uses for catechol molecules as inhibitors to glutathione s-transferase metabolic pathways |
| WO2019185413A1 (en) | 2018-03-27 | 2019-10-03 | Basf Se | Pesticidal substituted cyclopropyl derivatives |
| CN112423590B (zh) | 2018-05-15 | 2022-07-08 | 巴斯夫欧洲公司 | 包含benzpyrimoxan和oxazosulfyl的混合物和用途以及它们的施用方法 |
| WO2019224092A1 (en) | 2018-05-22 | 2019-11-28 | Basf Se | Pesticidally active c15-derivatives of ginkgolides |
| WO2020002472A1 (en) | 2018-06-28 | 2020-01-02 | Basf Se | Use of alkynylthiophenes as nitrification inhibitors |
| US20210340073A1 (en) | 2018-07-23 | 2021-11-04 | Basf Se | Use of substituted 2-thiazolines as nitrification inhibitors |
| EP3826982B1 (en) | 2018-07-23 | 2023-11-01 | Basf Se | Use of a substituted thiazolidine compound as nitrification inhibitor |
| EP3613736A1 (en) | 2018-08-22 | 2020-02-26 | Basf Se | Substituted glutarimide derivatives |
| AU2019348280A1 (en) | 2018-09-28 | 2021-04-22 | Basf Se | Method of controlling pests by seed treatment application of a mesoionic compound or mixture thereof |
| EP3628156A1 (en) | 2018-09-28 | 2020-04-01 | Basf Se | Method for controlling pests of sugarcane, citrus, rapeseed, and potato plants |
| EP3628158A1 (en) | 2018-09-28 | 2020-04-01 | Basf Se | Pesticidal mixture comprising a mesoionic compound and a biopesticide |
| EP3628157A1 (en) | 2018-09-28 | 2020-04-01 | Basf Se | Method of controlling insecticide resistant insects and virus transmission to plants |
| EP3643705A1 (en) | 2018-10-24 | 2020-04-29 | Basf Se | Pesticidal compounds |
| WO2020109039A1 (en) | 2018-11-28 | 2020-06-04 | Basf Se | Pesticidal compounds |
| WO2020126591A1 (en) | 2018-12-18 | 2020-06-25 | Basf Se | Substituted pyrimidinium compounds for combating animal pests |
| EP3696177A1 (en) | 2019-02-12 | 2020-08-19 | Basf Se | Heterocyclic compounds for the control of invertebrate pests |
| EP3769623A1 (en) | 2019-07-22 | 2021-01-27 | Basf Se | Mesoionic imidazolium compounds and derivatives for combating animal pests |
| US20220202017A1 (en) | 2019-05-29 | 2022-06-30 | Basf Se | Mesoionic imidazolium compounds and derivatives for combating animal pests |
| EP3766879A1 (en) | 2019-07-19 | 2021-01-20 | Basf Se | Pesticidal pyrazole derivatives |
| WO2022061914A1 (zh) * | 2020-09-28 | 2022-03-31 | 台州臻挚生物科技有限公司 | 一种3,5-二卤三氟苯乙酮及其衍生物的制备方法 |
| CN116829521A (zh) | 2021-02-02 | 2023-09-29 | 巴斯夫欧洲公司 | Dcd和烷氧基吡唑作为硝化抑制剂的协同增效作用 |
| AR125955A1 (es) | 2021-05-21 | 2023-08-30 | Basf Se | Uso de un compuesto de alcoxi pirazol n-funcionalizado como inhibidor de nitrificación |
| CA3219022A1 (en) | 2021-05-21 | 2022-11-24 | Barbara Nave | Use of ethynylpyridine compounds as nitrification inhibitors |
| EP4358725A1 (en) | 2021-06-21 | 2024-05-01 | Basf Se | Metal-organic frameworks with pyrazole-based building blocks |
| EP4358847A1 (en) | 2021-06-23 | 2024-05-01 | Kimtron, Inc. | System and method for ultra-close proximity irradiation of rotating biomass |
| WO2023203066A1 (en) | 2022-04-21 | 2023-10-26 | Basf Se | Synergistic action as nitrification inhibitors of dcd oligomers with alkoxypyrazole and its oligomers |
| WO2024028243A1 (en) | 2022-08-02 | 2024-02-08 | Basf Se | Pyrazolo pesticidal compounds |
| CN117263825A (zh) * | 2023-11-23 | 2023-12-22 | 内蒙古百灵科技有限公司 | 一种双甲脒结晶的方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102292331A (zh) * | 2009-01-22 | 2011-12-21 | 先正达参股股份有限公司 | 杀虫化合物 |
| WO2011104089A1 (en) * | 2010-02-25 | 2011-09-01 | Syngenta Participations Ag | Process for the preparation of isoxazoline derivatives |
| CA2807005C (en) * | 2010-08-05 | 2015-04-07 | Ah Usa 42 Llc | Isoxazoline derivatives as antiparasitic agents |
| WO2012086462A1 (ja) * | 2010-12-20 | 2012-06-28 | 日本曹達株式会社 | イソオキサゾリン化合物および有害生物防除剤 |
| RU2566083C3 (ru) * | 2011-03-10 | 2017-11-09 | Зоетис Сервисиз ЛЛК | Спироциклические производные изоксазолина в качестве противопаразитарных агентов |
-
2013
- 2013-08-28 NZ NZ704175A patent/NZ704175A/en unknown
- 2013-08-28 AU AU2013308887A patent/AU2013308887B2/en active Active
- 2013-08-28 RU RU2015107052A patent/RU2614978C2/ru active
- 2013-08-28 DK DK13756985.1T patent/DK2890699T3/en active
- 2013-08-28 PL PL13756985T patent/PL2890699T3/pl unknown
- 2013-08-28 WO PCT/US2013/056945 patent/WO2014036056A1/en active Application Filing
- 2013-08-28 CN CN201380044821.9A patent/CN104812758B/zh active Active
- 2013-08-28 MX MX2015002679A patent/MX351463B/es active IP Right Grant
- 2013-08-28 EP EP13756985.1A patent/EP2890699B1/en active Active
- 2013-08-28 RS RS20180636A patent/RS57284B1/sr unknown
- 2013-08-28 TR TR2018/07735T patent/TR201807735T4/tr unknown
- 2013-08-28 US US14/422,098 patent/US9200003B2/en active Active
- 2013-08-28 BR BR112015004135A patent/BR112015004135B8/pt active IP Right Grant
- 2013-08-28 SI SI201331062T patent/SI2890699T1/en unknown
- 2013-08-28 JP JP2015529970A patent/JP6109942B2/ja active Active
- 2013-08-28 KR KR1020157004953A patent/KR101736643B1/ko active IP Right Grant
- 2013-08-28 LT LTEP13756985.1T patent/LT2890699T/lt unknown
- 2013-08-28 PT PT137569851T patent/PT2890699T/pt unknown
- 2013-08-28 ES ES13756985.1T patent/ES2671271T3/es active Active
- 2013-08-28 HU HUE13756985A patent/HUE037667T2/hu unknown
- 2013-08-28 CA CA2881467A patent/CA2881467C/en active Active
- 2013-08-30 AR ARP130103110A patent/AR092409A1/es unknown
- 2013-12-13 NO NO13863231A patent/NO2931268T3/no unknown
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2015
- 2015-01-30 ZA ZA2015/00728A patent/ZA201500728B/en unknown
- 2015-02-11 CL CL2015000332A patent/CL2015000332A1/es unknown
- 2015-02-27 PH PH12015500441A patent/PH12015500441B1/en unknown
- 2015-10-12 HK HK15109932.5A patent/HK1209125A1/xx unknown
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2018
- 2018-05-30 HR HRP20180861TT patent/HRP20180861T1/hr unknown
- 2018-06-13 CY CY181100619T patent/CY1120611T1/el unknown
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