MX351463B - Formas cristalinas de 1-(5'-(5-(3,5-dicloro-4-fluorofenil)-5-(trif luorometil)-4,5-dihidroisoxazol-3-il)-3'h-espiro[azetidin-3,1'-is obenzofuran]-1-il)-2-(metilsulfonil)etanona. - Google Patents
Formas cristalinas de 1-(5'-(5-(3,5-dicloro-4-fluorofenil)-5-(trif luorometil)-4,5-dihidroisoxazol-3-il)-3'h-espiro[azetidin-3,1'-is obenzofuran]-1-il)-2-(metilsulfonil)etanona.Info
- Publication number
- MX351463B MX351463B MX2015002679A MX2015002679A MX351463B MX 351463 B MX351463 B MX 351463B MX 2015002679 A MX2015002679 A MX 2015002679A MX 2015002679 A MX2015002679 A MX 2015002679A MX 351463 B MX351463 B MX 351463B
- Authority
- MX
- Mexico
- Prior art keywords
- dihydroisoxazol
- isobenzofuran
- azetidine
- ethanone
- methylsulfonyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- C07D491/107—Spiro-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/14—Ectoparasiticides, e.g. scabicides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Abstract
La presente invención se refiere a nuevas modificaciones de 1-(5´-(5-(3,5-dicloro-4-fluorofenil)-5-(trifluorometil)-4,5-dihid roisoxazo-3-il)-3´H-espiro[azetidin-3,1´-isobenzofuran]-1-il)-2-( metilsulfonil)etanona; la presente invención también describe composiciones y métodos de tratamiento de una infección o infestación parasitaria en un animal que lo necesita; la presente invención se refiere también a un procedimiento para fabricar las formas cristalinas.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261695410P | 2012-08-31 | 2012-08-31 | |
| PCT/US2013/056945 WO2014036056A1 (en) | 2012-08-31 | 2013-08-28 | Crystalline forms of 1-(5'-(5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-3'h-spiro[azetidine-3,1'-isobenzofuran]-1-yl)-2-(methylsulfonyl)ethanone |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2015002679A MX2015002679A (es) | 2015-05-12 |
| MX351463B true MX351463B (es) | 2017-10-16 |
Family
ID=49115603
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2015002679A MX351463B (es) | 2012-08-31 | 2013-08-28 | Formas cristalinas de 1-(5'-(5-(3,5-dicloro-4-fluorofenil)-5-(trif luorometil)-4,5-dihidroisoxazol-3-il)-3'h-espiro[azetidin-3,1'-is obenzofuran]-1-il)-2-(metilsulfonil)etanona. |
Country Status (29)
| Country | Link |
|---|---|
| US (1) | US9200003B2 (es) |
| EP (1) | EP2890699B1 (es) |
| JP (1) | JP6109942B2 (es) |
| KR (1) | KR101736643B1 (es) |
| CN (1) | CN104812758B (es) |
| AR (1) | AR092409A1 (es) |
| AU (1) | AU2013308887B2 (es) |
| BR (1) | BR112015004135B8 (es) |
| CA (1) | CA2881467C (es) |
| CL (1) | CL2015000332A1 (es) |
| CY (1) | CY1120611T1 (es) |
| DK (1) | DK2890699T3 (es) |
| ES (1) | ES2671271T3 (es) |
| HK (1) | HK1209125A1 (es) |
| HR (1) | HRP20180861T1 (es) |
| HU (1) | HUE037667T2 (es) |
| LT (1) | LT2890699T (es) |
| MX (1) | MX351463B (es) |
| NO (1) | NO2931268T3 (es) |
| NZ (1) | NZ704175A (es) |
| PH (1) | PH12015500441B1 (es) |
| PL (1) | PL2890699T3 (es) |
| PT (1) | PT2890699T (es) |
| RS (1) | RS57284B1 (es) |
| RU (1) | RU2614978C2 (es) |
| SI (1) | SI2890699T1 (es) |
| TR (1) | TR201807735T4 (es) |
| WO (1) | WO2014036056A1 (es) |
| ZA (1) | ZA201500728B (es) |
Families Citing this family (68)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9221835B2 (en) * | 2012-09-07 | 2015-12-29 | Zoetis Services Llc | Spirocyclic derivatives as antiparasitic agents |
| JP5978478B2 (ja) | 2012-09-07 | 2016-08-24 | ゾエティス・サービシーズ・エルエルシー | スピロ環式イソオキサゾリン寄生虫駆除配合物 |
| US20160081986A1 (en) * | 2013-05-20 | 2016-03-24 | Zoetis Services Llc | Long-acting spiro-isoxazoline antiparasitic compositions |
| EP3204390B1 (en) | 2014-10-06 | 2019-06-05 | Basf Se | Substituted pyrimidinium compounds for combating animal pests |
| CN107873027A (zh) | 2014-11-06 | 2018-04-03 | 巴斯夫欧洲公司 | 用于防治无脊椎动物害虫的3‑吡啶基杂双环化合物 |
| US11064696B2 (en) | 2015-04-07 | 2021-07-20 | Basf Agrochemical Products B.V. | Use of an insecticidal carboxamide compound against pests on cultivated plants |
| WO2016198613A1 (en) | 2015-06-11 | 2016-12-15 | Basf Se | N-(thio)acylimino compounds |
| WO2016198611A1 (en) | 2015-06-11 | 2016-12-15 | Basf Se | N-(thio)acylimino heterocyclic compounds |
| WO2017016883A1 (en) | 2015-07-24 | 2017-02-02 | Basf Se | Process for preparation of cyclopentene compounds |
| MX2018004055A (es) | 2015-10-02 | 2019-02-20 | Basf Se | Compuestos de imino con un sustituyente de 2-cloropirimidin-5-ilo como agentes de control de plagas. |
| WO2017093163A1 (en) | 2015-11-30 | 2017-06-08 | Basf Se | Mixtures of cis-jasmone and bacillus amyloliquefaciens |
| CN108699075A (zh) | 2016-03-09 | 2018-10-23 | 巴斯夫欧洲公司 | 螺环衍生物 |
| BR112018068042A2 (pt) | 2016-03-11 | 2019-01-08 | Basf Se | métodos para controlar pragas de plantas, material de propagação de planta e uso de um ou mais compostos de fórmula i |
| JP7027329B2 (ja) | 2016-04-01 | 2022-03-01 | ビーエーエスエフ ソシエタス・ヨーロピア | 二環式化合物 |
| WO2018082962A1 (en) * | 2016-11-02 | 2018-05-11 | Basf Se | Process for preparation of tetrahydrothiophene derivatives |
| CN110291072A (zh) | 2016-12-16 | 2019-09-27 | 巴斯夫欧洲公司 | 农药化合物 |
| WO2018162312A1 (en) | 2017-03-10 | 2018-09-13 | Basf Se | Spirocyclic derivatives |
| WO2018166855A1 (en) | 2017-03-16 | 2018-09-20 | Basf Se | Heterobicyclic substituted dihydroisoxazoles |
| AU2018241406B2 (en) | 2017-03-28 | 2021-11-11 | Basf Se | Pesticidal compounds |
| BR112019018126A2 (pt) | 2017-03-31 | 2020-04-07 | Basf Se | composto, misturas, composição pesticida, métodos de controle de insetos, acarídeos ou nematoides, de proteção de plantas e de proteção de material de propagação vegetal e semente |
| WO2018192793A1 (en) | 2017-04-20 | 2018-10-25 | Basf Se | Substituted rhodanine derivatives |
| CN110582492A (zh) | 2017-04-26 | 2019-12-17 | 巴斯夫欧洲公司 | 作为农药的取代的琥珀酰亚胺衍生物 |
| KR20200005585A (ko) | 2017-05-10 | 2020-01-15 | 바스프 에스이 | 바이시클릭 화합물 |
| WO2018224455A1 (en) | 2017-06-07 | 2018-12-13 | Basf Se | Substituted cyclopropyl derivatives |
| WO2018229202A1 (en) | 2017-06-16 | 2018-12-20 | Basf Se | Mesoionic imidazolium compounds and derivatives for combating animal pests |
| BR112019025191B1 (pt) | 2017-06-19 | 2023-11-28 | Basf Se | Compostos de pirimidínio substituídos, composição, método para proteger culturas, semente revestida, uso dos compostos e uso de um composto |
| WO2018234488A1 (en) | 2017-06-23 | 2018-12-27 | Basf Se | SUBSTITUTED CYCLOPROPYL DERIVATIVES |
| WO2019042932A1 (en) | 2017-08-31 | 2019-03-07 | Basf Se | METHOD FOR CONTROLLING RICE PARASITES IN RICE |
| EP3453706A1 (en) | 2017-09-08 | 2019-03-13 | Basf Se | Pesticidal imidazole compounds |
| EP3694852A1 (en) | 2017-10-13 | 2020-08-19 | Basf Se | Imidazolidine pyrimidinium compounds for combating animal pests |
| US10807992B2 (en) | 2017-11-16 | 2020-10-20 | Avista Pharma Solutions, Inc. | Single enantiomer antiparasitic compounds |
| IL307992A (en) | 2017-12-15 | 2023-12-01 | Tarsus Pharmaceuticals Inc | Parasitic formulations containing isoxazoline and methods for treating blepharitis |
| WO2019121143A1 (en) | 2017-12-20 | 2019-06-27 | Basf Se | Substituted cyclopropyl derivatives |
| MX2020006566A (es) | 2017-12-21 | 2020-09-25 | Basf Se | Compuestos plaguicidas. |
| IL275726B1 (en) | 2018-01-09 | 2024-02-01 | Basf Se | Hetaryl silylethynyl compounds as nitrification inhibitors |
| WO2019137995A1 (en) | 2018-01-11 | 2019-07-18 | Basf Se | Novel pyridazine compounds for controlling invertebrate pests |
| PE20211753A1 (es) | 2018-02-28 | 2021-09-06 | Basf Se | Uso de alcoxipirazoles como inhibidores de la nitrificacion |
| PE20211754A1 (es) | 2018-02-28 | 2021-09-06 | Basf Se | Uso de compuestos de alcoxi pirazol funcionalizados con n como inhibidores de la nitrificacion |
| CN111683528B (zh) | 2018-02-28 | 2022-12-13 | 巴斯夫欧洲公司 | 吡唑炔丙基醚作为硝化抑制剂的用途 |
| WO2019175713A1 (en) | 2018-03-14 | 2019-09-19 | Basf Corporation | New catechol molecules and their use as inhibitors to p450 related metabolic pathways |
| WO2019175712A1 (en) | 2018-03-14 | 2019-09-19 | Basf Corporation | New uses for catechol molecules as inhibitors to glutathione s-transferase metabolic pathways |
| WO2019185413A1 (en) | 2018-03-27 | 2019-10-03 | Basf Se | Pesticidal substituted cyclopropyl derivatives |
| WO2019219529A1 (en) | 2018-05-15 | 2019-11-21 | Basf Se | Mixtures comprising benzpyrimoxan and oxazosulfyl and uses and methods of applying them |
| WO2019224092A1 (en) | 2018-05-22 | 2019-11-28 | Basf Se | Pesticidally active c15-derivatives of ginkgolides |
| WO2020002472A1 (en) | 2018-06-28 | 2020-01-02 | Basf Se | Use of alkynylthiophenes as nitrification inhibitors |
| EP3826983A1 (en) | 2018-07-23 | 2021-06-02 | Basf Se | Use of substituted 2-thiazolines as nitrification inhibitors |
| PL3826982T3 (pl) | 2018-07-23 | 2024-04-02 | Basf Se | Zastosowanie podstawionych związków tiazolidynowych jako inhibitora nitryfikacji |
| EP3613736A1 (en) | 2018-08-22 | 2020-02-26 | Basf Se | Substituted glutarimide derivatives |
| EP3628158A1 (en) | 2018-09-28 | 2020-04-01 | Basf Se | Pesticidal mixture comprising a mesoionic compound and a biopesticide |
| EP3628157A1 (en) | 2018-09-28 | 2020-04-01 | Basf Se | Method of controlling insecticide resistant insects and virus transmission to plants |
| WO2020064492A1 (en) | 2018-09-28 | 2020-04-02 | Basf Se | Method of controlling pests by seed treatment application of a mesoionic compound or mixture thereof |
| EP3628156A1 (en) | 2018-09-28 | 2020-04-01 | Basf Se | Method for controlling pests of sugarcane, citrus, rapeseed, and potato plants |
| EP3643705A1 (en) | 2018-10-24 | 2020-04-29 | Basf Se | Pesticidal compounds |
| US20220002284A1 (en) | 2018-11-28 | 2022-01-06 | Basf Se | Pesticidal compounds |
| WO2020126591A1 (en) | 2018-12-18 | 2020-06-25 | Basf Se | Substituted pyrimidinium compounds for combating animal pests |
| EP3696177A1 (en) | 2019-02-12 | 2020-08-19 | Basf Se | Heterocyclic compounds for the control of invertebrate pests |
| CN113923987A (zh) | 2019-05-29 | 2022-01-11 | 巴斯夫欧洲公司 | 用于防除动物害虫的介离子咪唑鎓化合物和衍生物 |
| EP3769623A1 (en) | 2019-07-22 | 2021-01-27 | Basf Se | Mesoionic imidazolium compounds and derivatives for combating animal pests |
| EP3766879A1 (en) | 2019-07-19 | 2021-01-20 | Basf Se | Pesticidal pyrazole derivatives |
| WO2022061914A1 (zh) * | 2020-09-28 | 2022-03-31 | 台州臻挚生物科技有限公司 | 一种3,5-二卤三氟苯乙酮及其衍生物的制备方法 |
| AU2022216425A1 (en) | 2021-02-02 | 2023-08-17 | Basf Se | Synergistic action of dcd and alkoxypyrazoles as nitrification inhibitors |
| AR125955A1 (es) | 2021-05-21 | 2023-08-30 | Basf Se | Uso de un compuesto de alcoxi pirazol n-funcionalizado como inhibidor de nitrificación |
| AR125954A1 (es) | 2021-05-21 | 2023-08-30 | Basf Se | Uso de compuestos de etinilpiridina como inhibidores de nitrificación |
| AU2022296764A1 (en) | 2021-06-21 | 2024-01-04 | Basf Se | Metal-organic frameworks with pyrazole-based building blocks |
| US11583602B2 (en) | 2021-06-23 | 2023-02-21 | Kimtron, Inc. | System and method for ultra-close proximity irradiation of rotating biomass |
| WO2023203066A1 (en) | 2022-04-21 | 2023-10-26 | Basf Se | Synergistic action as nitrification inhibitors of dcd oligomers with alkoxypyrazole and its oligomers |
| WO2024028243A1 (en) | 2022-08-02 | 2024-02-08 | Basf Se | Pyrazolo pesticidal compounds |
| CN117263825A (zh) * | 2023-11-23 | 2023-12-22 | 内蒙古百灵科技有限公司 | 一种双甲脒结晶的方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010084067A2 (en) * | 2009-01-22 | 2010-07-29 | Syngenta Participations Ag | Insecticidal compounds |
| KR20120133401A (ko) * | 2010-02-25 | 2012-12-10 | 신젠타 리미티드 | 이속사졸린 유도체의 제조 방법 |
| BR112013002871B1 (pt) * | 2010-08-05 | 2018-11-21 | Zoetis Llc | derivados de isoxazolina, seu uso e composição farmacêutica ou veterinária |
| WO2012086462A1 (ja) * | 2010-12-20 | 2012-06-28 | 日本曹達株式会社 | イソオキサゾリン化合物および有害生物防除剤 |
| EP2683723B1 (en) * | 2011-03-10 | 2016-05-25 | Zoetis Services LLC | Spirocyclic isoxazoline derivatives as antiparasitic agents |
-
2013
- 2013-08-28 NZ NZ704175A patent/NZ704175A/en unknown
- 2013-08-28 CN CN201380044821.9A patent/CN104812758B/zh active Active
- 2013-08-28 TR TR2018/07735T patent/TR201807735T4/tr unknown
- 2013-08-28 PT PT137569851T patent/PT2890699T/pt unknown
- 2013-08-28 ES ES13756985.1T patent/ES2671271T3/es active Active
- 2013-08-28 DK DK13756985.1T patent/DK2890699T3/en active
- 2013-08-28 RU RU2015107052A patent/RU2614978C2/ru active
- 2013-08-28 RS RS20180636A patent/RS57284B1/sr unknown
- 2013-08-28 HU HUE13756985A patent/HUE037667T2/hu unknown
- 2013-08-28 JP JP2015529970A patent/JP6109942B2/ja active Active
- 2013-08-28 LT LTEP13756985.1T patent/LT2890699T/lt unknown
- 2013-08-28 US US14/422,098 patent/US9200003B2/en active Active
- 2013-08-28 AU AU2013308887A patent/AU2013308887B2/en active Active
- 2013-08-28 EP EP13756985.1A patent/EP2890699B1/en active Active
- 2013-08-28 SI SI201331062T patent/SI2890699T1/en unknown
- 2013-08-28 MX MX2015002679A patent/MX351463B/es active IP Right Grant
- 2013-08-28 CA CA2881467A patent/CA2881467C/en active Active
- 2013-08-28 WO PCT/US2013/056945 patent/WO2014036056A1/en active Application Filing
- 2013-08-28 BR BR112015004135A patent/BR112015004135B8/pt active IP Right Grant
- 2013-08-28 KR KR1020157004953A patent/KR101736643B1/ko active IP Right Grant
- 2013-08-28 PL PL13756985T patent/PL2890699T3/pl unknown
- 2013-08-30 AR ARP130103110A patent/AR092409A1/es unknown
- 2013-12-13 NO NO13863231A patent/NO2931268T3/no unknown
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2015
- 2015-01-30 ZA ZA2015/00728A patent/ZA201500728B/en unknown
- 2015-02-11 CL CL2015000332A patent/CL2015000332A1/es unknown
- 2015-02-27 PH PH12015500441A patent/PH12015500441B1/en unknown
- 2015-10-12 HK HK15109932.5A patent/HK1209125A1/xx unknown
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2018
- 2018-05-30 HR HRP20180861TT patent/HRP20180861T1/hr unknown
- 2018-06-13 CY CY181100619T patent/CY1120611T1/el unknown
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