KR950702535A - 시그마 및 d₂-수용체 친화성을 가진 4-(4-플루오로페닐메틸)-피페리딘(4-(4-fluorophenylmethyl)-piperidines having sigma and d2-peceptor affinity) - Google Patents

시그마 및 d₂-수용체 친화성을 가진 4-(4-플루오로페닐메틸)-피페리딘(4-(4-fluorophenylmethyl)-piperidines having sigma and d2-peceptor affinity) Download PDF

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Publication number
KR950702535A
KR950702535A KR1019950700196A KR19950700196A KR950702535A KR 950702535 A KR950702535 A KR 950702535A KR 1019950700196 A KR1019950700196 A KR 1019950700196A KR 19950700196 A KR19950700196 A KR 19950700196A KR 950702535 A KR950702535 A KR 950702535A
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KR
South Korea
Prior art keywords
compound
formula
pharmaceutically acceptable
pharmaceutical composition
fluorophenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
KR1019950700196A
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English (en)
Korean (ko)
Inventor
라파엘 포켓
조르디 보로스
오레리오 사크리스탄
조세 오리쯔
Original Assignee
포겟 라파엘
페레르 인터내쇼날, 에스.에이.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by 포겟 라파엘, 페레르 인터내쇼날, 에스.에이. filed Critical 포겟 라파엘
Publication of KR950702535A publication Critical patent/KR950702535A/ko
Withdrawn legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1019950700196A 1993-05-18 1994-05-17 시그마 및 d₂-수용체 친화성을 가진 4-(4-플루오로페닐메틸)-피페리딘(4-(4-fluorophenylmethyl)-piperidines having sigma and d2-peceptor affinity) Withdrawn KR950702535A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SEP9301062 1993-05-18
ES09301062A ES2066721B1 (es) 1993-05-18 1993-05-18 Nuevos compuestos derivados de la piridina 1,4-disustituida.
PCT/EP1994/001594 WO1994026712A1 (en) 1993-05-18 1994-05-17 4-(4-fluorophenylmethyl)-piperidines having sigma and d2-receptor affinity

Publications (1)

Publication Number Publication Date
KR950702535A true KR950702535A (ko) 1995-07-29

Family

ID=8281846

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019950700196A Withdrawn KR950702535A (ko) 1993-05-18 1994-05-17 시그마 및 d₂-수용체 친화성을 가진 4-(4-플루오로페닐메틸)-피페리딘(4-(4-fluorophenylmethyl)-piperidines having sigma and d2-peceptor affinity)

Country Status (12)

Country Link
EP (1) EP0651744A1 (enrdf_load_stackoverflow)
JP (1) JPH07509255A (enrdf_load_stackoverflow)
KR (1) KR950702535A (enrdf_load_stackoverflow)
AU (1) AU675332B2 (enrdf_load_stackoverflow)
CA (1) CA2140260A1 (enrdf_load_stackoverflow)
ES (1) ES2066721B1 (enrdf_load_stackoverflow)
FI (1) FI950197L (enrdf_load_stackoverflow)
NO (1) NO301638B1 (enrdf_load_stackoverflow)
NZ (1) NZ267100A (enrdf_load_stackoverflow)
TW (1) TW252975B (enrdf_load_stackoverflow)
WO (1) WO1994026712A1 (enrdf_load_stackoverflow)
ZA (1) ZA943036B (enrdf_load_stackoverflow)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HN1999000149A (es) 1998-09-09 2000-01-12 Pfizer Prod Inc Derivados de 4,4-biarilpiperidina

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3576810A (en) * 1968-06-20 1971-04-27 Robins Co Inc A H 1-substituted-3-(-4)-aroylpiperidines
SE7409245L (enrdf_load_stackoverflow) * 1973-07-19 1975-01-20 Robins Co Inc A H
US3956296A (en) * 1974-12-11 1976-05-11 A. H. Robins Company, Incorporated 1-Substituted-4-benzylpiperidines
DK623586A (da) * 1985-12-27 1987-06-28 Eisai Co Ltd Piperidinderivater eller salte deraf og farmaceutiske kompositioner indeholdende forbindelserne
FR2681319B1 (fr) * 1991-09-12 1995-02-17 Synthelabo Derives de 1-(phenoxyalkyl)piperidine, leur preparation et leur application en therapeutique.
ES2060547B1 (es) * 1992-06-04 1995-06-16 Ferrer Int Mejoras en el objeto de la patente de invencion n/ 9201158 que se refiere a "procedimiento de obtencion de nuevos derivados de la 4-bencilpiperidina".

Also Published As

Publication number Publication date
FI950197A0 (fi) 1995-01-17
JPH07509255A (ja) 1995-10-12
ES2066721B1 (es) 1996-02-16
NO950062D0 (no) 1995-01-06
EP0651744A1 (en) 1995-05-10
FI950197A7 (fi) 1995-01-17
NO301638B1 (no) 1997-11-24
AU6928494A (en) 1994-12-12
NO950062L (no) 1995-01-06
AU675332B2 (en) 1997-01-30
WO1994026712A1 (en) 1994-11-24
ES2066721A1 (es) 1995-03-01
FI950197L (fi) 1995-01-17
ZA943036B (en) 1995-05-02
CA2140260A1 (en) 1994-11-24
TW252975B (enrdf_load_stackoverflow) 1995-08-01
NZ267100A (en) 1996-09-25

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Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 19950118

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
PC1203 Withdrawal of no request for examination
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid