KR950701075A - 생물학적 유체내 리간드의 양을 측정하는 방법 및 이를 수행하기 위한 키트(Method for determination of the amount of a ligand in a biololgical fluid and kit for carrying out such a method) - Google Patents

생물학적 유체내 리간드의 양을 측정하는 방법 및 이를 수행하기 위한 키트(Method for determination of the amount of a ligand in a biololgical fluid and kit for carrying out such a method)

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Publication number
KR950701075A
KR950701075A KR1019940703529A KR19940703529A KR950701075A KR 950701075 A KR950701075 A KR 950701075A KR 1019940703529 A KR1019940703529 A KR 1019940703529A KR 19940703529 A KR19940703529 A KR 19940703529A KR 950701075 A KR950701075 A KR 950701075A
Authority
KR
South Korea
Prior art keywords
ligand
amount
test tube
thyroid hormone
pct
Prior art date
Application number
KR1019940703529A
Other languages
English (en)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6458274&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR950701075(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed filed Critical
Publication of KR950701075A publication Critical patent/KR950701075A/ko

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G01N33/78Thyroid gland hormones, e.g. T3, T4, TBH, TBG or their receptors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306Solid-phase reaction mechanisms
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854Immunoglobulins
    • G01N33/686Anti-idiotype
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/961Chemistry: molecular biology and microbiology including a step of forming, releasing, or exposing the antigen or forming the hapten-immunogenic carrier complex or the antigen per se
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/962Prevention or removal of interfering materials or reactants or other treatment to enhance results, e.g. determining or preventing nonspecific binding
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/968High energy substrates, e.g. fluorescent, chemiluminescent, radioactive
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/971Capture of complex after antigen-antibody reaction
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/975Kit
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/807Apparatus included in process claim, e.g. physical support structures
    • Y10S436/808Automated or kit
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/815Test for named compound or class of compounds
    • Y10S436/817Steroids or hormones
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/822Identified hapten
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/824Immunological separation techniques

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
KR1019940703529A 1992-05-06 1994-10-06 생물학적 유체내 리간드의 양을 측정하는 방법 및 이를 수행하기 위한 키트(Method for determination of the amount of a ligand in a biololgical fluid and kit for carrying out such a method) KR950701075A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4214922A DE4214922C2 (de) 1992-05-06 1992-05-06 Verfahren zur quantitativen Bestimmung des Anteils der freien Form eines Schilddrüsenhormon-Liganden in einer biologischen Flüssigkeit und Kit zur Durchführung eines solchen Verfahrens
PCT/EP1993/000981 WO1993022675A1 (en) 1992-05-06 1993-04-22 Method for the determination of the amount of a ligand in a biological fluid and kit for carrying out such a method

Publications (1)

Publication Number Publication Date
KR950701075A true KR950701075A (ko) 1995-02-20

Family

ID=6458274

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019940703529A KR950701075A (ko) 1992-05-06 1994-10-06 생물학적 유체내 리간드의 양을 측정하는 방법 및 이를 수행하기 위한 키트(Method for determination of the amount of a ligand in a biololgical fluid and kit for carrying out such a method)

Country Status (12)

Country Link
US (1) US5639670A (ko)
EP (1) EP0639272B2 (ko)
JP (1) JP3234947B2 (ko)
KR (1) KR950701075A (ko)
AT (1) ATE142339T1 (ko)
AU (1) AU4040993A (ko)
CA (1) CA2132830A1 (ko)
DE (2) DE4214922C2 (ko)
FI (1) FI944658A (ko)
HU (1) HUT69994A (ko)
NO (1) NO943759D0 (ko)
WO (1) WO1993022675A1 (ko)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4328070C1 (de) * 1993-08-20 1994-11-24 Henning Berlin Gmbh Verfahren zur Bestimmung eines Analyten in einem Volumen einer flüssigen Probe sowie seine Anwendung zur Bestimmung von anti-TSH-Rezeptor-Autoantikörpern in einem Patientenserum
DE19548028A1 (de) * 1995-12-21 1997-06-26 Bayer Ag Verfahren zur Herstellung eines synthetischen Kalibrators für den Einsatz in Sandwich-Immunoassays, bestehend aus einem Antikörper gegen einen der im Assay benutzten Antikörper und einer Sequenz des Analyten
US7271009B1 (en) * 1997-11-18 2007-09-18 Bio-Rad Laboratories, Inc. Multi-analyte diagnostic test for thyroid disorders
US6153440A (en) * 1998-09-23 2000-11-28 The Regents Of The University Of California Simultaneous measurement of free triiodothyronine and free thyroxine by equilibrium dialysis and immunoassay
DE19907094C1 (de) 1999-02-19 2000-04-13 Brahms Diagnostica Gmbh Verwendung von blockierenden Anti-TSH-Rezeptor-Antikörpern bei der Therapie von Hyperthyreosen sowie monoklonale Antikörper für eine solche Verwendung
CA2406321C (en) * 2000-04-13 2008-02-26 Bio-Rad Laboratories, Inc. Multi-analyte diagnostic test for thyroid disorders
US8956823B2 (en) * 2007-08-20 2015-02-17 Bio-Rad Laboratories, Inc. Anti-antibody reagent
ES2654906T3 (es) 2013-11-05 2018-02-15 Roche Diagnostics Gmbh Método para determinar la cantidad total y/o la concentración de un analito en presencia de una molécula ligante, así como kits, composiciones y usos relacionados con el mismo
CN108802369A (zh) * 2018-05-31 2018-11-13 湖南远璟生物技术有限公司 一种游离三碘甲状腺原氨酸磁微粒化学发光免疫定量检测试剂盒及其制备方法
CN108802361A (zh) * 2018-05-31 2018-11-13 湖南远璟生物技术有限公司 一种四碘甲状腺原氨酸酶结合物的制备方法
CN108802370A (zh) * 2018-05-31 2018-11-13 湖南远璟生物技术有限公司 一种三碘甲状腺原氨酸酶结合物的制备方法
CN108562752A (zh) * 2018-05-31 2018-09-21 湖南远璟生物技术有限公司 一种游离甲状腺素磁微粒化学发光免疫定量检测试剂盒及其制备方法
CN113125697B (zh) * 2019-12-31 2024-03-26 科美博阳诊断技术(上海)有限公司 一种睾酮均相化学发光检测试剂盒及其应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS604422B2 (ja) * 1976-10-07 1985-02-04 持田製薬株式会社 抗原の定量方法
US4366143A (en) * 1979-09-24 1982-12-28 Amersham International Public Limited Company Assay for the free portion of substances in biological fluids
EP0103605B1 (en) * 1982-03-19 1990-12-05 EKINS, Roger Philip Method for free ligand assays
US5304498A (en) * 1982-03-19 1994-04-19 Ekins Roger Philip Method and composition for free ligand assay
EP0089806B1 (en) * 1982-03-22 1989-06-28 AMERSHAM INTERNATIONAL plc Assay for the free portion of substances in biological fluids
DE3377531D1 (en) * 1982-09-29 1988-09-01 Serono Diagnostics Ltd Immunoassay of antigens
ZA837119B (en) * 1982-10-07 1984-12-24 Amersham Int Plc Assay for the free portion of substances in biological fluids
GB8317124D0 (en) * 1983-06-23 1983-07-27 Ekins R P Free ligand assay
GB2158578B (en) * 1984-05-08 1988-03-09 Farmos Group Ltd Immunometric method for the determination of a hapten
DE3727238A1 (de) * 1987-08-14 1989-02-23 Henning Berlin Gmbh Immunologisches bestimmungsverfahren zur bestimmung von hapteneigenschaften aufweisenden freien substanzen
GB8800419D0 (en) * 1988-01-08 1988-02-10 Amersham Int Plc Method for measuring free fraction of ligands in biological fluids
GB8812213D0 (en) * 1988-05-24 1988-06-29 Ares Serono Res & Dev Ltd Method of assay

Also Published As

Publication number Publication date
EP0639272B2 (en) 2002-07-10
ATE142339T1 (de) 1996-09-15
JP3234947B2 (ja) 2001-12-04
HUT69994A (en) 1995-09-28
DE4214922A1 (de) 1993-11-11
JPH07507388A (ja) 1995-08-10
DE69304528D1 (de) 1996-10-10
NO943759L (no) 1994-10-06
EP0639272B1 (en) 1996-09-04
WO1993022675A1 (en) 1993-11-11
DE69304528T2 (de) 1997-03-20
HU9402865D0 (en) 1995-01-30
CA2132830A1 (en) 1993-11-11
EP0639272A1 (en) 1995-02-22
AU4040993A (en) 1993-11-29
FI944658A0 (fi) 1994-10-05
DE4214922C2 (de) 1996-06-13
DE69304528T3 (de) 2002-12-05
FI944658A (fi) 1994-10-05
US5639670A (en) 1997-06-17
NO943759D0 (no) 1994-10-06

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