KR950007805A - 인대 및 건 회복용 흡수성 구조물 (Absorbable structures for ligament and tendon repair) - Google Patents
인대 및 건 회복용 흡수성 구조물 (Absorbable structures for ligament and tendon repair) Download PDFInfo
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- KR950007805A KR950007805A KR1019940024682A KR19940024682A KR950007805A KR 950007805 A KR950007805 A KR 950007805A KR 1019940024682 A KR1019940024682 A KR 1019940024682A KR 19940024682 A KR19940024682 A KR 19940024682A KR 950007805 A KR950007805 A KR 950007805A
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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- A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
- A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
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Abstract
본 발명은, 생흡수성 합성 물질의 기공층, 생흡수성 필름 및 생흡수성 생중합체 스폰지 층으로 이루어진 나선형 층들을 포함하는 다중층 나선형 롤 형태의 손상된 인대 및/또는 건을 회복시키기 위한 완전 흡수성 인공기관에 관한 것이다. 본 발명은 또한, 생흡수성 물질의 기공층과 생흡수성 필름을 적층시키는 단계, 생성된 적층물을 생흡수성 중합체를 포함하는 수성 겔의 층으로 피복시키는 단계 및 적층물과 겔 층을 동그랗게 말아서 나선형 롤로 만든 다음 겔을 건조시켜 생흡수성 스폰지의 층을 형성하는 단계를 포함하는, 상기 인공기관의 제조방법을 제공한다.
기공층은 인장 강도가 큰 생흡수성 합성 중합체를 포함하는 것이 바람직하다. 생흡수성 필름과 스폰지 층은 콜라겐과 같은 화학물질 지향성 생중합체를 포함하는 것이 바람직이다.
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (27)
- 합성 생흡수성 물질인 기공층, 생흡수성 필름 및 생흡수성 스폰지 층으로 이루어진 나선형 층들을 포함하는 다중층으로 이루어진 나선형 롤 형태의 생흡수성 인대 또는 건 인공기관.
- 제1항에 있어서, 다중층 나선형 롤의 직경이 1.2내지 21㎜인 생흡수성 인공기관.
- 제1항 또는 제2항에 있어서, 기공층이 락트산 및/또는 글리콜산의 중합체 또는 공중합체, 산화 재생 셀룰로즈, 플리디옥사논(PDS), 락트산과 ε-카프로락탐의 공중합체, 폴리하이드록시부티르산, 또는 하이드록시부티르산과 하이드록시발레르산의 공중합체를 포함하는 생흡수성 인공기관.
- 제1항 내지 제3항 중의 어느 한 항에 있어서, 기공층이 생흡수성 필름 또는 스폰지 층 속에 삽입된 생흡수성 인공기관.
- 제1항 내지 제4항 중의 어느 한 항에 있어서, 기공층의 최대 두께가 0.02내지 0.3㎜의 범위인 생흡수성 인공기관.
- 제1항 내지 제5항 중의 어느 한 항에 있어서, 생흡수성 필름이 생중합체 또는 화학적으로 가교결합된 생중합체 유도체를 포함하는 생흡수성 인공기관.
- 제6항에 있어서, 생중합체가 콜라겐 또는 글리코스아미노글리칸을 포함하는 생흡수성 인공기관.
- 제1항 내지 제7항 중의 어느 한 항에 있어서, 오일 미세액적이 생흡수성 필름에 분산되어 있는 생흡수성 인공기관.
- 제8항에 있어서, 오일이 생흡수성 필름의 중량을 기준으로 하여 1내지 90중량%의 양으로 존재하는 생흡수성 인공기관.
- 제1항 내지 제9항 중의 어느 한 항에 있어서, 생흡수성 필름의 두께가 0.01내지 0.1㎜의 범위인 생흡수성 인공기관.
- 제1항 내지 제10항 중의 어느 한 항에 있어서, 생흡수성 스폰지가 생중합체 또는 화학적으로 가교결합된 생중합체 유도체인 생흡수성 인공기관.
- 제11항에 있어서, 생흡수성 스폰지가 콜라겐 또는 글리코스아미노글리칸을 포함하는 생흡수성 인공기관.
- 제1항 내지 제12항 중의 어느 한 항에 있어서, 생흡수성 스폰지에 분산된 생흡수성 오일의 미세액적을 추가로 포함하는 생흡수성 인공기관.
- 제13항에 있어서, 생흡수성 오일이 생흡수성 스폰지의 중량을 기준으로 하여 1내지 90중량%의 양으로 존재하는 생흡수성 인공기관.
- 제1항 내지 제14항 중의 어느 한 항에 있어서, 생분해성 스폰지 층의 두께가 0.5내지 2.5㎜의 범위인 생흡수성 인공기관.
- 실질적으로 제1도에 도시되어 있는 바와 같은 생흡수성 인공기관.
- 손상된 건 또는 인대 회복용 외과 이식 조직을 제조하기 위한, 제1항 내지 제16항 중의 어느 한 항에 따르는 생흡수성 인공기관의 용도.
- 생흡수성 물질의 기공층과 생흡수성 필름을 적층시키는 단계, 생성된 적층물을 생흡수성 중합체를 포함하는 수성 겔층으로 피복하는 단계, 적층물과 겔 층을 동그랗게 말아서 나선형 롤로 만드는 단계 및 겔을 건조시켜 생흡수성 스폰지 층을 형성하는 단계를 포함하는, 손상된 인대 또는 건물 외과적으로 회복하는데 사용하기 위한 생흡수성 인공기관의 제조방법.
- 제18항에 있어서, 동그랗게 마는 단계가 360° 완전 회전을 2내지 6회 수행함을 포함하는, 생흡수성 인공기판의 제조방법.
- 제18항 또는 제19항에 있어서, 생흡수성 필름의 제조단계가 생흡수성 물질의 수용액 또는 현탁액의 층을 제조한 다음 이를 건조시키는 단계를 포함하는, 생흡수성 인공기관의 제조방법.
- 제20항에 있어서, 생흡수성 물질의 수용액 또는 현탁액의 층을 생흡수성 합성 물질의 기공층 위에 피복시키거나 생흡수성 합성 물질의 층을 생흡수성 물질의 수용액 또는 현탁액의 층속에 참지시키는, 생흡수성 인공기관의 제조방법.
- 제20항 또는 제21항에 있어서, 생흡수성 오일을 생흡수성 물질의 수용액 또는 현탁액 속에 유화시키는 단계를 추가로 포함하는 생흡수성 인공기관의 제조방법.
- 제18항 내지 제22항 중의 어느 한 항에 있어서, 수성 겔이 산으로 팽윤된 콜라겐을 포함하는, 생흡수성 인공기관의 제조방법.
- 제18항 내지 제23항 중의 어느 한 항에 있어서, 수성 겔속에 생흡수성 오일을 유화시키는 단계를 추가로 포함하는, 생흡수성 인공기관의 제조방법.
- 제18항 내지 제24항 중의 어느 한 항에 있어서, 겔을 건조시켜 생흡수성 스폰지를 형성하는 단계가, 겔을 동결시킨 다음 감압하에 물을 중발시킴으로써 동결건조시키는 단계를 포함하는, 생흡수성 인공기관의 제조방법.
- 제18항 내지 제25항 중의 어느 한 항에 있어서, 겔을 건조시켜 생흡수성 스폰지를 형성하는 단계가, 겔을 동결시킨 다음 동결된 겔을 용매 건조시키는 단계를 포함하는, 생흡수성 인공기관의 제조방법.
- 실질적으로 실시예에 기술되어 있는 바와 같은 생흡수성 인공기관의 제조방법.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (2)
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GB9320100A GB2282328B (en) | 1993-09-29 | 1993-09-29 | Absorbable structures for ligament and tendon repair |
GB9320100.2 | 1993-09-29 |
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KR950007805A true KR950007805A (ko) | 1995-04-15 |
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KR1019940024682A KR950007805A (ko) | 1993-09-29 | 1994-09-29 | 인대 및 건 회복용 흡수성 구조물 (Absorbable structures for ligament and tendon repair) |
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US (2) | US5514181A (ko) |
EP (1) | EP0645149B1 (ko) |
JP (1) | JP2963015B2 (ko) |
KR (1) | KR950007805A (ko) |
AT (1) | ATE180977T1 (ko) |
AU (1) | AU673769B2 (ko) |
CA (1) | CA2133028A1 (ko) |
ES (1) | ES2134907T3 (ko) |
GB (1) | GB2282328B (ko) |
HK (1) | HK1002251A1 (ko) |
IN (1) | IN182132B (ko) |
MY (1) | MY114130A (ko) |
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-
1993
- 1993-09-29 GB GB9320100A patent/GB2282328B/en not_active Expired - Fee Related
-
1994
- 1994-09-19 ZA ZA947263A patent/ZA947263B/xx unknown
- 1994-09-19 IN IN752CA1994 patent/IN182132B/en unknown
- 1994-09-27 CA CA002133028A patent/CA2133028A1/en not_active Abandoned
- 1994-09-28 MY MYPI94002577A patent/MY114130A/en unknown
- 1994-09-28 EP EP94307076A patent/EP0645149B1/en not_active Expired - Lifetime
- 1994-09-28 JP JP6257351A patent/JP2963015B2/ja not_active Expired - Fee Related
- 1994-09-28 AT AT94307076T patent/ATE180977T1/de not_active IP Right Cessation
- 1994-09-28 AU AU74306/94A patent/AU673769B2/en not_active Ceased
- 1994-09-28 ES ES94307076T patent/ES2134907T3/es not_active Expired - Lifetime
- 1994-09-29 US US08/314,986 patent/US5514181A/en not_active Expired - Lifetime
- 1994-09-29 KR KR1019940024682A patent/KR950007805A/ko not_active Application Discontinuation
- 1994-10-14 TW TW083109525A patent/TW298565B/zh active
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1995
- 1995-06-07 US US08/485,244 patent/US5595621A/en not_active Expired - Lifetime
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1998
- 1998-02-16 HK HK98101185A patent/HK1002251A1/xx not_active IP Right Cessation
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ES2134907T3 (es) | 1999-10-16 |
ZA947263B (en) | 1996-03-19 |
GB2282328B (en) | 1997-10-08 |
EP0645149B1 (en) | 1999-06-09 |
HK1002251A1 (en) | 1998-08-07 |
EP0645149A1 (en) | 1995-03-29 |
IN182132B (ko) | 1999-01-09 |
US5595621A (en) | 1997-01-21 |
US5514181A (en) | 1996-05-07 |
JP2963015B2 (ja) | 1999-10-12 |
JPH07250889A (ja) | 1995-10-03 |
AU673769B2 (en) | 1996-11-21 |
AU7430694A (en) | 1995-04-13 |
ATE180977T1 (de) | 1999-06-15 |
GB2282328A (en) | 1995-04-05 |
TW298565B (ko) | 1997-02-21 |
CA2133028A1 (en) | 1995-03-30 |
MY114130A (en) | 2002-08-30 |
GB9320100D0 (en) | 1993-11-17 |
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