DE69739928D1 - Gewebetransplantat aus der Magensubmukosa zur Reparatur neurologischen Gewebes - Google Patents

Gewebetransplantat aus der Magensubmukosa zur Reparatur neurologischen Gewebes

Info

Publication number
DE69739928D1
DE69739928D1 DE69739928T DE69739928T DE69739928D1 DE 69739928 D1 DE69739928 D1 DE 69739928D1 DE 69739928 T DE69739928 T DE 69739928T DE 69739928 T DE69739928 T DE 69739928T DE 69739928 D1 DE69739928 D1 DE 69739928D1
Authority
DE
Germany
Prior art keywords
tissue
repair
neurological
stomach submucosa
graft
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69739928T
Other languages
English (en)
Inventor
Mark A Cobb
Stephen F Badylak
Gary Isom
Archana Sharma
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Purdue Research Foundation
Original Assignee
Purdue Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Purdue Research Foundation filed Critical Purdue Research Foundation
Application granted granted Critical
Publication of DE69739928D1 publication Critical patent/DE69739928D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/37—Digestive system
    • A61K35/38—Stomach; Intestine; Goblet cells; Oral mucosa; Saliva
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1825—Fibroblast growth factor [FGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/185—Nerve growth factor [NGF]; Brain derived neurotrophic factor [BDNF]; Ciliary neurotrophic factor [CNTF]; Glial derived neurotrophic factor [GDNF]; Neurotrophins, e.g. NT-3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0679—Cells of the gastro-intestinal tract
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/13—Nerve growth factor [NGF]; Brain-derived neurotrophic factor [BDNF]; Cilliary neurotrophic factor [CNTF]; Glial-derived neurotrophic factor [GDNF]; Neurotrophins [NT]; Neuregulins
DE69739928T 1996-09-16 1997-09-16 Gewebetransplantat aus der Magensubmukosa zur Reparatur neurologischen Gewebes Expired - Lifetime DE69739928D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US2619796P 1996-09-16 1996-09-16

Publications (1)

Publication Number Publication Date
DE69739928D1 true DE69739928D1 (de) 2010-08-19

Family

ID=21830422

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69727483T Expired - Lifetime DE69727483T2 (de) 1996-09-16 1997-09-16 Gewebetransplantat aus der magensubmukosa zur reparatur neurologischen gewebes
DE69739928T Expired - Lifetime DE69739928D1 (de) 1996-09-16 1997-09-16 Gewebetransplantat aus der Magensubmukosa zur Reparatur neurologischen Gewebes

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE69727483T Expired - Lifetime DE69727483T2 (de) 1996-09-16 1997-09-16 Gewebetransplantat aus der magensubmukosa zur reparatur neurologischen gewebes

Country Status (9)

Country Link
US (1) US6241981B1 (de)
EP (1) EP0925067B1 (de)
JP (1) JP4572009B2 (de)
AU (1) AU731768B2 (de)
CA (1) CA2263898C (de)
DE (2) DE69727483T2 (de)
DK (1) DK0925067T3 (de)
ES (1) ES2213835T3 (de)
WO (1) WO1998010775A1 (de)

Families Citing this family (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6334872B1 (en) 1994-02-18 2002-01-01 Organogenesis Inc. Method for treating diseased or damaged organs
US6485723B1 (en) * 1995-02-10 2002-11-26 Purdue Research Foundation Enhanced submucosal tissue graft constructs
US20020095218A1 (en) 1996-03-12 2002-07-18 Carr Robert M. Tissue repair fabric
EP0925077B1 (de) * 1996-08-23 2003-10-15 Cook Biotech, Inc. Verfahren zur gewinnung einer gereignigten matrix auf kollagenbasis aus submukosa gewebe
US6666892B2 (en) 1996-08-23 2003-12-23 Cook Biotech Incorporated Multi-formed collagenous biomaterial medical device
JP4341049B2 (ja) * 1998-06-05 2009-10-07 オルガノジェネシス インク． 生物工学により作成したチューブ状移植片補綴
CA2334228C (en) * 1998-06-05 2010-09-28 Organogenesis Inc. Bioengineered vascular graft support prostheses
JP4606583B2 (ja) * 1998-06-05 2011-01-05 オルガノジェネシス インク． 生物工学的手法による平面シート状移植補綴
JP4341050B2 (ja) * 1998-06-05 2009-10-07 オルガノジェネシス インク． 生体工学により作成した血管移植片補綴
US6448076B2 (en) 1998-09-15 2002-09-10 The Regents Of The University Of Michigan Method for chemically acellularizing a biological tissue sample
US6918396B1 (en) 1998-12-01 2005-07-19 Purdue Research Foundation Method for vocal cord reconstruction
US8882850B2 (en) 1998-12-01 2014-11-11 Cook Biotech Incorporated Multi-formed collagenous biomaterial medical device
WO2000032254A1 (en) * 1998-12-01 2000-06-08 Purdue Research Foundation Method for vocal cord reconstruction
EP1320390A2 (de) * 2000-09-18 2003-06-25 Organogenesis Inc. Bioartifizielle flache schichtförmige prothesen und ihre verwendung
DE10146903C1 (de) * 2001-09-24 2002-11-14 Cytonet Gmbh & Co Kg Verfahren zur Herstellung von in vitro-Hohlorganen
US8529956B2 (en) 2002-03-18 2013-09-10 Carnell Therapeutics Corporation Methods and apparatus for manufacturing plasma based plastics and bioplastics produced therefrom
US20100254900A1 (en) * 2002-03-18 2010-10-07 Campbell Phil G Biocompatible polymers and Methods of use
CA2483908C (en) * 2002-05-02 2012-02-21 Purdue Research Foundation Vascularization enhanced graft constructs
NZ536563A (en) * 2002-05-02 2008-03-28 Purdue Research Foundation Vascularization enhanced graft constructs
EP1503789A4 (de) * 2002-05-02 2006-08-02 Purdue Research Foundation Durch vaskularisierung verstärkte prothesenkonstrukte
US7326571B2 (en) 2003-07-17 2008-02-05 Boston Scientific Scimed, Inc. Decellularized bone marrow extracellular matrix
US20050125049A1 (en) * 2003-10-21 2005-06-09 The Regents Of The University Of Michigan Tissue engineered vascular construct and method for producing same
WO2005077433A1 (en) * 2004-02-09 2005-08-25 Cook Biotech Incorporated Stent graft devices having collagen coating
WO2006050459A2 (en) * 2004-10-28 2006-05-11 Cook Incorporated Methods and systems for modifying vascular valves
US20060292227A1 (en) * 2005-06-23 2006-12-28 Mcpherson Timothy B Extracellular matrix material particles and methods of preparation
EP2093256A3 (de) 2005-07-28 2009-10-14 Carnegie Mellon University Biokompatible Polymere und Verwendungsverfahren
CN1903144A (zh) * 2005-07-29 2007-01-31 广东冠昊生物科技有限公司 生物型人工韧带及其制备方法
CN1903143A (zh) * 2005-07-29 2007-01-31 广东冠昊生物科技有限公司 生物型人工血管及其制备方法
CN100482178C (zh) * 2005-08-04 2009-04-29 广东冠昊生物科技有限公司 带生物膜的血管瘤夹
CN1986007B (zh) * 2005-12-20 2011-09-14 广东冠昊生物科技股份有限公司 生物型外科补片
CN1986006A (zh) * 2005-12-20 2007-06-27 广州知光生物科技有限公司 生物型神经导管
CN1986001B (zh) * 2005-12-20 2011-09-14 广东冠昊生物科技股份有限公司 生物护创膜
CN1985778B (zh) * 2005-12-20 2010-10-13 广东冠昊生物科技股份有限公司 生物型人工角膜
US20100023129A1 (en) * 2008-07-22 2010-01-28 Guo-Feng Xu Jawbone prosthesis and method of manufacture
CN101332316B (zh) * 2008-07-22 2012-12-26 广东冠昊生物科技股份有限公司 生物型鼻梁植入体
CN101332314B (zh) * 2008-07-22 2012-11-14 广东冠昊生物科技股份有限公司 生物型关节软骨修补件
US8529959B2 (en) 2006-10-17 2013-09-10 Carmell Therapeutics Corporation Methods and apparatus for manufacturing plasma based plastics and bioplastics produced therefrom
US8764828B2 (en) * 2007-02-02 2014-07-01 The Regents Of The University Of Michigan System and method for forming bone, ligament, and bone-ligament constructs
US8361503B2 (en) 2007-03-02 2013-01-29 University of Pittsburgh—of the Commonwealth System of Higher Education Extracellular matrix-derived gels and related methods
US8679176B2 (en) 2007-12-18 2014-03-25 Cormatrix Cardiovascular, Inc Prosthetic tissue valve
US8257434B2 (en) 2007-12-18 2012-09-04 Cormatrix Cardiovascular, Inc. Prosthetic tissue valve
US8735054B1 (en) 2008-01-04 2014-05-27 Lifecell Corporation Acellular tissue matrix preservation solution
US9150318B1 (en) 2009-01-02 2015-10-06 Lifecell Corporation Method for sterilizing an acellular tissue matrix
WO2010096458A1 (en) * 2009-02-18 2010-08-26 Cormatrix Cardiovascular, Inc. Compositions and methods for preventing cardiac arrhythmia
US20100267143A1 (en) * 2009-04-16 2010-10-21 Snu R&Db Foundation Method for Surface Modification of Polymeric Scaffold for Stem Cell Transplantation Using Decellularized Extracellular Matrix
SG194880A1 (en) 2011-05-27 2013-12-30 Cormatrix Cardiovascular Inc Sterilized, acellular extracellular matrix compositions and methods ofmaking thereof
US9011368B2 (en) * 2013-09-25 2015-04-21 Amanda C. Rivera-Begeman Methods for improving cerebrospinal fluid flow
US9878071B2 (en) 2013-10-16 2018-01-30 Purdue Research Foundation Collagen compositions and methods of use
JP6681872B2 (ja) 2014-03-21 2020-04-15 ユニバーシティ オブ ピッツバーグ −オブ ザ コモンウェルス システム オブ ハイヤー エデュケイション 細胞外マトリクス由来最終滅菌ヒドロゲルの調製方法
WO2016172365A1 (en) 2015-04-21 2016-10-27 Purdue Research Foundation Office Of Technology Commercialization Cell-collagen-silica composites and methods of making and using the same
FR3058321B1 (fr) 2016-11-07 2020-01-31 Tbf Genie Tissulaire (Tbf) Guide implantable pour la regeneration tissulaire
EP3589294B1 (de) 2017-03-02 2022-10-26 University of Pittsburgh - Of the Commonwealth System of Higher Education Hydrogel aus extrazellulärer matrix (ecm) und lösliche fraktion davon zur verwendung in der behandlung von krebs
EP4252842A3 (de) 2017-03-02 2023-10-25 University of Pittsburgh- Of the Commonwealth System of Higher Education Ecm-hydrogel zur behandlung von ösophagealer entzündung
EP3615568A4 (de) 2017-04-25 2021-01-20 Purdue Research Foundation Dreidimensionaler (3d) gewebegezüchteter muskel zur geweberestauration
KR20190141775A (ko) 2017-05-05 2019-12-24 유니버시티 오브 피츠버그 - 오브 더 커먼웰쓰 시스템 오브 하이어 에듀케이션 기질 결합 소낭의 안구에의 적용
US11826490B1 (en) 2020-12-29 2023-11-28 Acell, Inc. Extracellular matrix sheet devices with improved mechanical properties and method of making

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4902508A (en) * 1988-07-11 1990-02-20 Purdue Research Foundation Tissue graft composition
ES2185615T3 (es) * 1990-05-16 2003-05-01 Southern Res Inst Uso y liberacion controlada de las microcapsulas para estimular el crecimiento de la fibra nerviosa.
US5281422A (en) 1991-09-24 1994-01-25 Purdue Research Foundation Graft for promoting autogenous tissue growth
US5275826A (en) * 1992-11-13 1994-01-04 Purdue Research Foundation Fluidized intestinal submucosa and its use as an injectable tissue graft
GB2282328B (en) 1993-09-29 1997-10-08 Johnson & Johnson Medical Absorbable structures for ligament and tendon repair
US5695998A (en) * 1995-02-10 1997-12-09 Purdue Research Foundation Submucosa as a growth substrate for islet cells
US5711969A (en) * 1995-04-07 1998-01-27 Purdue Research Foundation Large area submucosal tissue graft constructs

Also Published As

Publication number Publication date
US6241981B1 (en) 2001-06-05
WO1998010775A1 (en) 1998-03-19
JP2001500512A (ja) 2001-01-16
DE69727483D1 (de) 2004-03-11
EP0925067A4 (de) 2001-05-30
AU4348597A (en) 1998-04-02
DK0925067T3 (da) 2004-05-03
JP4572009B2 (ja) 2010-10-27
CA2263898C (en) 2009-12-08
CA2263898A1 (en) 1998-03-19
EP0925067A1 (de) 1999-06-30
ES2213835T3 (es) 2004-09-01
EP0925067B1 (de) 2004-02-04
AU731768B2 (en) 2001-04-05
DE69727483T2 (de) 2004-11-25

Similar Documents

Publication Publication Date Title
DE69739928D1 (de) Gewebetransplantat aus der Magensubmukosa zur Reparatur neurologischen Gewebes
DE69734218D1 (de) Gewebetransplantat aus der Magensubmukosa
DE69737285D1 (de) Perforierte Transplantatkonstruktionen aus submukosalem Gewebe
ID18204A (id) Pembuatan poliamida dari aminonitril
DE69621612D1 (de) Gewebetransplantat aus der submucosa der harnblase
DE59700503D1 (de) Abdrucksystem für einen aus der menschlichen gewebestruktur austretenden implantatabschluss
DE59703559D1 (de) Schnellanschlusskupplung
DE59710628D1 (de) Starres endoskop mit beleuchtung
ID15886A (id) Pembuatan alkil ester secara kontiniu dari asam met-akrilik
ID15885A (id) Pembuatan alkil ester secara kontiniu dari asam met-akrilik
ID17664A (id) Pembuatan kaprolaktam dari 6-aminokapronitril
ID22707A (id) Komposisi pembersih
BR9500921A (pt) Conjunto de barra de tração de tipo sem folga
DE69713417T2 (de) Transversale Wirbelsäulenverbindungsvorrichtung
DE29618012U1 (de) Gerät zur Reinigung der Zunge
DE59702174D1 (de) Anhängevorrichtung
NO971973L (no) Tilhenger- eller påsalingsplog
DE29611694U1 (de) Anhängevorrichtung
FR2743915B1 (fr) Ardoise communiquante
DE29607752U1 (de) Lotstab
DE29611811U1 (de) Filtrationsanlage
DE29614764U1 (de) Wasserspeicher
DE29712325U1 (de) Wasserspeicher
DE59802707D1 (de) Schaltungsanordnung zur zweidraht-vierdraht-umsetzung
DE29613091U1 (de) Interfaceschaltung zur Realisierung einer S/T-Schnittstelle nach Spezifikation ITU I.430