KR940703827A - - Google Patents
Info
- Publication number
- KR940703827A KR940703827A KR19940702080A KR19940702080A KR940703827A KR 940703827 A KR940703827 A KR 940703827A KR 19940702080 A KR19940702080 A KR 19940702080A KR 19940702080 A KR19940702080 A KR 19940702080A KR 940703827 A KR940703827 A KR 940703827A
- Authority
- KR
- South Korea
- Prior art keywords
- compound
- formula
- disclosed
- pharmaceutically acceptable
- effective amount
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Ophthalmology & Optometry (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Cardiology (AREA)
- Nutrition Science (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Immunology (AREA)
- Hospice & Palliative Care (AREA)
- Anesthesiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Materials For Medical Uses (AREA)
- Saccharide Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US81065191A | 1991-12-18 | 1991-12-18 | |
| PCT/US1992/010698 WO1993012107A1 (en) | 1991-12-18 | 1992-12-16 | Imidazoylalkyl substituted with a six membered nitrogen containing heterocyclic ring |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR940703827A true KR940703827A (enExample) | 1994-12-12 |
| KR0142801B1 KR0142801B1 (en) | 1998-07-15 |
Family
ID=25204344
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR94702080A Expired - Fee Related KR0142801B1 (en) | 1991-12-18 | 1992-12-16 | Imidazoylalkyl substituted with a six membered nitrogen containing heterocyclic ring t |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP0619818B1 (enExample) |
| JP (1) | JPH07121938B2 (enExample) |
| KR (1) | KR0142801B1 (enExample) |
| AT (1) | ATE140223T1 (enExample) |
| AU (1) | AU665604B2 (enExample) |
| CA (1) | CA2126086C (enExample) |
| DE (1) | DE69212164T2 (enExample) |
| DK (1) | DK0619818T3 (enExample) |
| ES (1) | ES2089782T3 (enExample) |
| GR (1) | GR3021195T3 (enExample) |
| HK (1) | HK31097A (enExample) |
| IL (1) | IL104124A (enExample) |
| MX (1) | MX9207392A (enExample) |
| MY (1) | MY108904A (enExample) |
| NZ (1) | NZ246434A (enExample) |
| SG (1) | SG44565A1 (enExample) |
| TW (1) | TW263503B (enExample) |
| WO (1) | WO1993012107A1 (enExample) |
| ZA (1) | ZA929785B (enExample) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL9302045A (nl) * | 1993-08-27 | 1995-03-16 | Vrije Universiteit | Nieuwe imidazoolafgeleide met agonistische of antagonistische activiteit op de histamine H3-receptor. |
| AU7823894A (en) * | 1993-08-27 | 1995-03-21 | Vrije Universiteit | New imidazole derivatives having agonistic or antagonistic activity on the histamine h3 receptor |
| FR2732017B1 (fr) * | 1995-03-21 | 2000-09-22 | Inst Nat Sante Rech Med | Nouveaux derives de l'imidazole antagonistes et/ou agonistes du recepteur h3 de l'histamine, leur preparation et leurs applications therapeutiques |
| WO1997018813A1 (en) * | 1995-11-22 | 1997-05-29 | Merck & Co., Inc. | Inhibitors of farnesyl-protein transferase |
| AU715603B2 (en) * | 1996-04-03 | 2000-02-03 | Merck & Co., Inc. | Inhibitors of farnesyl-protein transferase |
| US6072057A (en) * | 1996-06-06 | 2000-06-06 | Gliatech Inc. | 1H-4(5)-cyclo-substituted imidazole derivatives as histamine H3 receptor agents |
| US6407132B1 (en) | 1997-07-25 | 2002-06-18 | James Black Foundation Limited | Substituted imidazole derivatives and their use as histamine H3 receptor ligands |
| KR20010031839A (ko) * | 1997-11-07 | 2001-04-16 | 둘락 노먼 씨. | 한 개의 질소원자를 함유하는 5, 6 또는 7원헤테로사이클릭 환으로 치환된 이미다조일알킬 |
| US6034251A (en) * | 1997-11-07 | 2000-03-07 | Schering Corporation | Phenyl-alkyl-imidazoles |
| US5990147A (en) * | 1997-11-07 | 1999-11-23 | Schering Corporation | H3 receptor ligands of the phenyl-alkyl-imidazoles type |
| PT1036065E (pt) * | 1997-12-04 | 2004-09-30 | Allergan Inc | Derivados de imidazol substituidos com actividade do tipo agonista nos receptores alfa 2b ou 2b/2c adrenergicos |
| US6133291A (en) * | 1998-10-16 | 2000-10-17 | Schering Corporation | N-(imidazolylalkyl)substituted cyclic amines as histamine-H3 agonists or antagonists |
| US6100279A (en) * | 1998-11-05 | 2000-08-08 | Schering Corporation | Imidazoylalkyl substituted with a five, six or seven membered heterocyclic ring containing one nitrogen atom |
| WO2000042023A1 (en) | 1999-01-18 | 2000-07-20 | Novo Nordisk A/S | Substituted imidazoles, their preparation and use |
| US6211182B1 (en) * | 1999-03-08 | 2001-04-03 | Schering Corporation | Imidazole compounds substituted with a six or seven membered heterocyclic ring containing two nitrogen atoms |
| US6908926B1 (en) | 1999-04-16 | 2005-06-21 | Novo Nordisk A/S | Substituted imidazoles, their preparation and use |
| US6437147B1 (en) | 2000-03-17 | 2002-08-20 | Novo Nordisk | Imidazole compounds |
| US6610721B2 (en) | 2000-03-17 | 2003-08-26 | Novo Nordisk A/S | Imidazo heterocyclic compounds |
| EP1313470A4 (en) | 2000-08-17 | 2005-02-16 | Gliatech Inc | NEW ALICYCLIC IMIDAZOLE AS H 3 ACTIVE SUBSTANCES |
| US6951944B2 (en) | 2002-02-21 | 2005-10-04 | Azwell Inc. | Production of imidazole derivatives and novel intermediates of the derivatives |
| EP1707203A1 (en) | 2005-04-01 | 2006-10-04 | Bioprojet | Treatment of parkinson's disease obstructive sleep apnea, dementia with lewy bodies, vascular dementia with non-imidazole alkylamines histamine H3- receptor ligands |
| EP1717233A1 (en) | 2005-04-29 | 2006-11-02 | Bioprojet | Histamine H3-receptor ligands and their therapeutic application |
| EP1717235A3 (en) | 2005-04-29 | 2007-02-28 | Bioprojet | Phenoxypropylpiperidines and -pyrrolidines and their use as histamine H3-receptor ligands |
| SI2076508T1 (sl) | 2006-10-18 | 2011-04-29 | Pfizer Prod Inc | Spojine biaril eter sečnine |
| WO2013151982A1 (en) | 2012-04-03 | 2013-10-10 | Arena Pharmaceuticals, Inc. | Methods and compounds useful in treating pruritus, and methods for identifying such compounds |
| US11114499B2 (en) | 2018-01-02 | 2021-09-07 | Seoul Viosys Co., Ltd. | Display device having light emitting stacked structure |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2579596B1 (fr) * | 1985-03-26 | 1987-11-20 | Inst Nat Sante Rech Med | (imidazolyl-4) piperidines, leur preparation et leur application en therapeutique |
| FR2586562B1 (fr) * | 1985-09-02 | 1989-03-10 | Inst Nat Sante Rech Med | Composition pharmaceutique contenant de l'a-methylhistamine |
| EP0372125A1 (en) * | 1988-11-08 | 1990-06-13 | Akzo N.V. | Oxazole and thiazole derivatives |
| US4925851A (en) * | 1989-05-23 | 1990-05-15 | Sandoz Pharmaceuticals Corp. | 2- or 4-substituted-[2-(1H-imidazol-1-yl)ethyl]piperidines |
-
1992
- 1992-12-16 JP JP5511084A patent/JPH07121938B2/ja not_active Expired - Lifetime
- 1992-12-16 AT AT93901399T patent/ATE140223T1/de not_active IP Right Cessation
- 1992-12-16 SG SG1996002412A patent/SG44565A1/en unknown
- 1992-12-16 WO PCT/US1992/010698 patent/WO1993012107A1/en not_active Ceased
- 1992-12-16 AU AU32758/93A patent/AU665604B2/en not_active Ceased
- 1992-12-16 KR KR94702080A patent/KR0142801B1/ko not_active Expired - Fee Related
- 1992-12-16 ES ES93901399T patent/ES2089782T3/es not_active Expired - Lifetime
- 1992-12-16 DK DK93901399.1T patent/DK0619818T3/da active
- 1992-12-16 NZ NZ246434A patent/NZ246434A/en unknown
- 1992-12-16 CA CA002126086A patent/CA2126086C/en not_active Expired - Fee Related
- 1992-12-16 EP EP93901399A patent/EP0619818B1/en not_active Expired - Lifetime
- 1992-12-16 DE DE69212164T patent/DE69212164T2/de not_active Expired - Fee Related
- 1992-12-17 TW TW081110145A patent/TW263503B/zh active
- 1992-12-17 ZA ZA929785A patent/ZA929785B/xx unknown
- 1992-12-17 MY MYPI92002333A patent/MY108904A/en unknown
- 1992-12-17 MX MX9207392A patent/MX9207392A/es not_active IP Right Cessation
- 1992-12-17 IL IL10412492A patent/IL104124A/en not_active IP Right Cessation
-
1996
- 1996-09-30 GR GR960402550T patent/GR3021195T3/el unknown
-
1997
- 1997-03-13 HK HK31097A patent/HK31097A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| IL104124A (en) | 1998-12-06 |
| DE69212164T2 (de) | 1996-12-05 |
| ZA929785B (en) | 1993-06-21 |
| ES2089782T3 (es) | 1996-10-01 |
| ATE140223T1 (de) | 1996-07-15 |
| WO1993012107A1 (en) | 1993-06-24 |
| TW263503B (enExample) | 1995-11-21 |
| SG44565A1 (en) | 1997-12-19 |
| NZ246434A (en) | 1996-02-27 |
| HK31097A (en) | 1997-03-21 |
| MY108904A (en) | 1996-11-30 |
| IL104124A0 (en) | 1993-05-13 |
| CA2126086C (en) | 2000-03-28 |
| KR0142801B1 (en) | 1998-07-15 |
| JPH06511252A (ja) | 1994-12-15 |
| EP0619818A1 (en) | 1994-10-19 |
| CA2126086A1 (en) | 1993-06-24 |
| AU3275893A (en) | 1993-07-19 |
| MX9207392A (es) | 1993-06-01 |
| DK0619818T3 (da) | 1996-11-25 |
| EP0619818B1 (en) | 1996-07-10 |
| JPH07121938B2 (ja) | 1995-12-25 |
| AU665604B2 (en) | 1996-01-11 |
| GR3021195T3 (en) | 1996-12-31 |
| DE69212164D1 (de) | 1996-08-14 |
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| TW263503B (enExample) | ||
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| TW268950B (enExample) | ||
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| WO1999024421A8 (en) | Imidazoylalkyl substituted with a five, six or seven membered heterocyclic ring containing one nitrogen atom | |
| NO172640C (no) | Analogifremgangsmaate ved fremstilling av terapeutisk aktive piperazinderivater | |
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| NO165195C (no) | Analogifremgangsmaate for fremstilling av terapeutisk aktive nye derivater av 4,5-dihydro-oksazolyl-2-((2-pyridyl)-metyl-tio- eller metylsulfinyl)-benz- eller tienoimidazoler. | |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0105 | International application |
St.27 status event code: A-0-1-A10-A15-nap-PA0105 |
|
| R17-X000 | Change to representative recorded |
St.27 status event code: A-3-3-R10-R17-oth-X000 |
|
| A201 | Request for examination | ||
| P11-X000 | Amendment of application requested |
St.27 status event code: A-2-2-P10-P11-nap-X000 |
|
| P13-X000 | Application amended |
St.27 status event code: A-2-2-P10-P13-nap-X000 |
|
| PA0201 | Request for examination |
St.27 status event code: A-1-2-D10-D11-exm-PA0201 |
|
| PG1501 | Laying open of application |
St.27 status event code: A-1-1-Q10-Q12-nap-PG1501 |
|
| E902 | Notification of reason for refusal | ||
| PE0902 | Notice of grounds for rejection |
St.27 status event code: A-1-2-D10-D21-exm-PE0902 |
|
| T11-X000 | Administrative time limit extension requested |
St.27 status event code: U-3-3-T10-T11-oth-X000 |
|
| T11-X000 | Administrative time limit extension requested |
St.27 status event code: U-3-3-T10-T11-oth-X000 |
|
| T11-X000 | Administrative time limit extension requested |
St.27 status event code: U-3-3-T10-T11-oth-X000 |
|
| P11-X000 | Amendment of application requested |
St.27 status event code: A-2-2-P10-P11-nap-X000 |
|
| P13-X000 | Application amended |
St.27 status event code: A-2-2-P10-P13-nap-X000 |
|
| E701 | Decision to grant or registration of patent right | ||
| PE0701 | Decision of registration |
St.27 status event code: A-1-2-D10-D22-exm-PE0701 |
|
| GRNT | Written decision to grant | ||
| PR0701 | Registration of establishment |
St.27 status event code: A-2-4-F10-F11-exm-PR0701 |
|
| PR1002 | Payment of registration fee |
St.27 status event code: A-2-2-U10-U12-oth-PR1002 Fee payment year number: 1 |
|
| PG1601 | Publication of registration |
St.27 status event code: A-4-4-Q10-Q13-nap-PG1601 |
|
| LAPS | Lapse due to unpaid annual fee | ||
| PC1903 | Unpaid annual fee |
St.27 status event code: A-4-4-U10-U13-oth-PC1903 Not in force date: 20010404 Payment event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE |
|
| PC1903 | Unpaid annual fee |
St.27 status event code: N-4-6-H10-H13-oth-PC1903 Ip right cessation event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE Not in force date: 20010404 |
|
| R18-X000 | Changes to party contact information recorded |
St.27 status event code: A-5-5-R10-R18-oth-X000 |
|
| R18-X000 | Changes to party contact information recorded |
St.27 status event code: A-5-5-R10-R18-oth-X000 |