ZA929785B - Imidazoylalkyl substituted with a six membered nitrogen containing heterocyclic ring. - Google Patents
Imidazoylalkyl substituted with a six membered nitrogen containing heterocyclic ring.Info
- Publication number
- ZA929785B ZA929785B ZA929785A ZA929785A ZA929785B ZA 929785 B ZA929785 B ZA 929785B ZA 929785 A ZA929785 A ZA 929785A ZA 929785 A ZA929785 A ZA 929785A ZA 929785 B ZA929785 B ZA 929785B
- Authority
- ZA
- South Africa
- Prior art keywords
- compound
- formula
- disclosed
- heterocyclic ring
- containing heterocyclic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Ophthalmology & Optometry (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Immunology (AREA)
- Heart & Thoracic Surgery (AREA)
- Anesthesiology (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Nutrition Science (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Materials For Medical Uses (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US81065191A | 1991-12-18 | 1991-12-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA929785B true ZA929785B (en) | 1993-06-21 |
Family
ID=25204344
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA929785A ZA929785B (en) | 1991-12-18 | 1992-12-17 | Imidazoylalkyl substituted with a six membered nitrogen containing heterocyclic ring. |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP0619818B1 (xx) |
| JP (1) | JPH07121938B2 (xx) |
| KR (1) | KR0142801B1 (xx) |
| AT (1) | ATE140223T1 (xx) |
| AU (1) | AU665604B2 (xx) |
| CA (1) | CA2126086C (xx) |
| DE (1) | DE69212164T2 (xx) |
| DK (1) | DK0619818T3 (xx) |
| ES (1) | ES2089782T3 (xx) |
| GR (1) | GR3021195T3 (xx) |
| HK (1) | HK31097A (xx) |
| IL (1) | IL104124A (xx) |
| MX (1) | MX9207392A (xx) |
| MY (1) | MY108904A (xx) |
| NZ (1) | NZ246434A (xx) |
| SG (1) | SG44565A1 (xx) |
| TW (1) | TW263503B (xx) |
| WO (1) | WO1993012107A1 (xx) |
| ZA (1) | ZA929785B (xx) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1995006037A1 (en) * | 1993-08-27 | 1995-03-02 | Vrije Universiteit | New imidazole derivatives having agonistic or antagonistic activity on the histamine h3 receptor |
| NL9302045A (nl) * | 1993-08-27 | 1995-03-16 | Vrije Universiteit | Nieuwe imidazoolafgeleide met agonistische of antagonistische activiteit op de histamine H3-receptor. |
| FR2732017B1 (fr) * | 1995-03-21 | 2000-09-22 | Inst Nat Sante Rech Med | Nouveaux derives de l'imidazole antagonistes et/ou agonistes du recepteur h3 de l'histamine, leur preparation et leurs applications therapeutiques |
| WO1997018813A1 (en) * | 1995-11-22 | 1997-05-29 | Merck & Co., Inc. | Inhibitors of farnesyl-protein transferase |
| CA2250353A1 (en) * | 1996-04-03 | 1997-10-09 | Christopher J. Dinsmore | Inhibitors of farnesyl-protein transferase |
| US6072057A (en) * | 1996-06-06 | 2000-06-06 | Gliatech Inc. | 1H-4(5)-cyclo-substituted imidazole derivatives as histamine H3 receptor agents |
| US6407132B1 (en) | 1997-07-25 | 2002-06-18 | James Black Foundation Limited | Substituted imidazole derivatives and their use as histamine H3 receptor ligands |
| HUP0102662A3 (en) * | 1997-11-07 | 2003-01-28 | Schering Corp | Imidazoylalkyl substituted with a five, six or seven membered heterocyclic ring containing one nitrogen atom |
| US5990147A (en) * | 1997-11-07 | 1999-11-23 | Schering Corporation | H3 receptor ligands of the phenyl-alkyl-imidazoles type |
| US6034251A (en) * | 1997-11-07 | 2000-03-07 | Schering Corporation | Phenyl-alkyl-imidazoles |
| RU2235092C2 (ru) * | 1997-12-04 | 2004-08-27 | Оллерган Инк. | Замещенные производные имидазола, способ введения активного соединения и способ лечения на основе этих соединений |
| US6133291A (en) * | 1998-10-16 | 2000-10-17 | Schering Corporation | N-(imidazolylalkyl)substituted cyclic amines as histamine-H3 agonists or antagonists |
| US6100279A (en) * | 1998-11-05 | 2000-08-08 | Schering Corporation | Imidazoylalkyl substituted with a five, six or seven membered heterocyclic ring containing one nitrogen atom |
| AU3033100A (en) | 1999-01-18 | 2000-08-01 | Boehringer Ingelheim International Gmbh | Substituted imidazoles, their preparation and use |
| US6211182B1 (en) * | 1999-03-08 | 2001-04-03 | Schering Corporation | Imidazole compounds substituted with a six or seven membered heterocyclic ring containing two nitrogen atoms |
| US6908926B1 (en) | 1999-04-16 | 2005-06-21 | Novo Nordisk A/S | Substituted imidazoles, their preparation and use |
| US6610721B2 (en) | 2000-03-17 | 2003-08-26 | Novo Nordisk A/S | Imidazo heterocyclic compounds |
| US6437147B1 (en) | 2000-03-17 | 2002-08-20 | Novo Nordisk | Imidazole compounds |
| WO2002013821A1 (en) | 2000-08-17 | 2002-02-21 | Gliatech, Inc. | Novel alicyclic imidazoles as h3 agents |
| JPWO2003070722A1 (ja) * | 2002-02-21 | 2005-06-09 | アルフレッサファーマ株式会社 | イミダゾール誘導体の改良製法およびその新規中間体 |
| EP1707203A1 (en) | 2005-04-01 | 2006-10-04 | Bioprojet | Treatment of parkinson's disease obstructive sleep apnea, dementia with lewy bodies, vascular dementia with non-imidazole alkylamines histamine H3- receptor ligands |
| EP1717233A1 (en) | 2005-04-29 | 2006-11-02 | Bioprojet | Histamine H3-receptor ligands and their therapeutic application |
| EP1717235A3 (en) | 2005-04-29 | 2007-02-28 | Bioprojet | Phenoxypropylpiperidines and -pyrrolidines and their use as histamine H3-receptor ligands |
| PL2076508T3 (pl) | 2006-10-18 | 2011-05-31 | Pfizer Prod Inc | Związki biaryloeteru mocznika |
| WO2013151982A1 (en) | 2012-04-03 | 2013-10-10 | Arena Pharmaceuticals, Inc. | Methods and compounds useful in treating pruritus, and methods for identifying such compounds |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2579596B1 (fr) * | 1985-03-26 | 1987-11-20 | Inst Nat Sante Rech Med | (imidazolyl-4) piperidines, leur preparation et leur application en therapeutique |
| FR2586562B1 (fr) * | 1985-09-02 | 1989-03-10 | Inst Nat Sante Rech Med | Composition pharmaceutique contenant de l'a-methylhistamine |
| EP0372125A1 (en) * | 1988-11-08 | 1990-06-13 | Akzo N.V. | Oxazole and thiazole derivatives |
| US4925851A (en) * | 1989-05-23 | 1990-05-15 | Sandoz Pharmaceuticals Corp. | 2- or 4-substituted-[2-(1H-imidazol-1-yl)ethyl]piperidines |
-
1992
- 1992-12-16 CA CA002126086A patent/CA2126086C/en not_active Expired - Fee Related
- 1992-12-16 SG SG1996002412A patent/SG44565A1/en unknown
- 1992-12-16 EP EP93901399A patent/EP0619818B1/en not_active Expired - Lifetime
- 1992-12-16 WO PCT/US1992/010698 patent/WO1993012107A1/en active IP Right Grant
- 1992-12-16 KR KR94702080A patent/KR0142801B1/ko not_active IP Right Cessation
- 1992-12-16 DK DK93901399.1T patent/DK0619818T3/da active
- 1992-12-16 AU AU32758/93A patent/AU665604B2/en not_active Ceased
- 1992-12-16 AT AT93901399T patent/ATE140223T1/de not_active IP Right Cessation
- 1992-12-16 ES ES93901399T patent/ES2089782T3/es not_active Expired - Lifetime
- 1992-12-16 DE DE69212164T patent/DE69212164T2/de not_active Expired - Fee Related
- 1992-12-16 JP JP5511084A patent/JPH07121938B2/ja not_active Expired - Lifetime
- 1992-12-16 NZ NZ246434A patent/NZ246434A/en unknown
- 1992-12-17 ZA ZA929785A patent/ZA929785B/xx unknown
- 1992-12-17 MY MYPI92002333A patent/MY108904A/en unknown
- 1992-12-17 IL IL10412492A patent/IL104124A/en not_active IP Right Cessation
- 1992-12-17 TW TW081110145A patent/TW263503B/zh active
- 1992-12-17 MX MX9207392A patent/MX9207392A/es not_active IP Right Cessation
-
1996
- 1996-09-30 GR GR960402550T patent/GR3021195T3/el unknown
-
1997
- 1997-03-13 HK HK31097A patent/HK31097A/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| IL104124A0 (en) | 1993-05-13 |
| GR3021195T3 (en) | 1996-12-31 |
| MY108904A (en) | 1996-11-30 |
| CA2126086C (en) | 2000-03-28 |
| SG44565A1 (en) | 1997-12-19 |
| NZ246434A (en) | 1996-02-27 |
| HK31097A (en) | 1997-03-21 |
| KR940703827A (xx) | 1994-12-12 |
| CA2126086A1 (en) | 1993-06-24 |
| ES2089782T3 (es) | 1996-10-01 |
| IL104124A (en) | 1998-12-06 |
| WO1993012107A1 (en) | 1993-06-24 |
| EP0619818B1 (en) | 1996-07-10 |
| TW263503B (xx) | 1995-11-21 |
| JPH06511252A (ja) | 1994-12-15 |
| AU665604B2 (en) | 1996-01-11 |
| MX9207392A (es) | 1993-06-01 |
| EP0619818A1 (en) | 1994-10-19 |
| DE69212164D1 (de) | 1996-08-14 |
| DK0619818T3 (da) | 1996-11-25 |
| KR0142801B1 (en) | 1998-07-15 |
| DE69212164T2 (de) | 1996-12-05 |
| JPH07121938B2 (ja) | 1995-12-25 |
| AU3275893A (en) | 1993-07-19 |
| ATE140223T1 (de) | 1996-07-15 |
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