KR940000829B1 - 항정신병성 융합-환의 피리디닐 피페라진 유도체의 제조방법 - Google Patents

항정신병성 융합-환의 피리디닐 피페라진 유도체의 제조방법 Download PDF

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Publication number
KR940000829B1
KR940000829B1 KR1019860003445A KR860003445A KR940000829B1 KR 940000829 B1 KR940000829 B1 KR 940000829B1 KR 1019860003445 A KR1019860003445 A KR 1019860003445A KR 860003445 A KR860003445 A KR 860003445A KR 940000829 B1 KR940000829 B1 KR 940000829B1
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KR
South Korea
Prior art keywords
compound
hydrogen
formula
lower alkyl
preparing
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KR1019860003445A
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English (en)
Korean (ko)
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KR860009008A (ko
Inventor
스트워트 뉴 제임스
피. 예비취 죠셉
Original Assignee
브리스톨-마이어즈 스퀴브 캄파니
이삭 쟈코브스키
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Publication of KR860009008A publication Critical patent/KR860009008A/ko
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Publication of KR940000829B1 publication Critical patent/KR940000829B1/ko

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
KR1019860003445A 1985-05-06 1986-05-02 항정신병성 융합-환의 피리디닐 피페라진 유도체의 제조방법 KR940000829B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US73120185A 1985-05-06 1985-05-06
US731,201 1985-05-06

Publications (2)

Publication Number Publication Date
KR860009008A KR860009008A (ko) 1986-12-19
KR940000829B1 true KR940000829B1 (ko) 1994-02-02

Family

ID=24938510

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019860003445A KR940000829B1 (ko) 1985-05-06 1986-05-02 항정신병성 융합-환의 피리디닐 피페라진 유도체의 제조방법

Country Status (25)

Country Link
JP (1) JPH0753728B2 (es)
KR (1) KR940000829B1 (es)
CN (1) CN1017901B (es)
AT (1) AT398572B (es)
AU (1) AU593244B2 (es)
BE (1) BE904724A (es)
CA (1) CA1278792C (es)
CH (1) CH672787A5 (es)
DE (1) DE3615180C2 (es)
DK (1) DK165745C (es)
EG (1) EG18206A (es)
ES (6) ES8801250A1 (es)
FI (1) FI85484C (es)
FR (1) FR2581385B1 (es)
GB (1) GB2174703B (es)
GR (1) GR861149B (es)
HU (1) HU195509B (es)
IE (1) IE59201B1 (es)
IT (1) IT1208607B (es)
LU (1) LU86421A1 (es)
MY (1) MY100777A (es)
NL (1) NL8601146A (es)
PT (1) PT82523B (es)
SE (1) SE465270B (es)
ZA (1) ZA862046B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5801186A (en) * 1987-11-20 1998-09-01 Hoechst Marion Roussel, Inc. 3- 4-(1-substituted-4-piperazinyl)butyl!-4-thiazolidinone and related compounds
US4880930A (en) * 1987-11-30 1989-11-14 New James S Psychotropic acyclic amide derivatives
US4780466A (en) * 1988-03-17 1988-10-25 Hoechst-Roussel Pharmaceuticals, Inc. Arylpiperazinylalkoxy derivatives of cyclic imides
IE903410A1 (en) * 1989-10-09 1991-04-10 Novo Nordisk As Indole derivatives, their preparation and use
US5272148A (en) * 1992-09-09 1993-12-21 Hoechst-Roussel Pharmaceuticals Incorporated Heteroarenylpiperazines
FR2738822B1 (fr) * 1995-09-15 1997-10-31 Synthelabo Derives de 4-(omega-(4-(thieno(3,2-c)pyridin-4-yl)piperazin- 1-yl)alkyl)quinolein-2(1h)-one, leur preparation et leur application en therapeutique
FR2738823B1 (fr) * 1995-09-15 1997-10-31 Synthelabo Derives de 3-(omega-(4-(thieno(3,2-c)pyridin-4-yl)piperazin- 1-yl)alkyl)-3,4-dihydroquinolein-2(1h)-one,leur preparation et leur application en therapeutique
FR2738824B1 (fr) * 1995-09-15 1997-10-31 Synthelabo Derives de 3-(omega(4-(thieno(3,2-c)pyridin-4-yl)piperazin-1 -yl)alkyl)-3,4-dihydroquinazolin-2(1h)-one,leur preparation et leur application en therapeutique
JP3335362B2 (ja) * 1995-09-15 2002-10-15 サノフィ―サンテラボ キノレイン−２（１ｈ）−オン誘導体セロトニンアンタゴニスト
FR2761071B1 (fr) * 1997-03-20 1999-12-03 Synthelabo Derives de quinolein-2(1h)-one et de dihydroquinolein-2(1h)- one, leur preparation et leur application en therapeutique
FR2797874B1 (fr) * 1999-08-27 2002-03-29 Adir Nouveaux derives de la pyridine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4367335A (en) * 1981-08-03 1983-01-04 Mead Johnson & Company Thiazolidinylalkylene piperazine derivatives
US4452799A (en) * 1981-12-23 1984-06-05 Mead Johnson & Company Benzisothiazole and benzisoxazole piperazine derivatives
US4361565A (en) * 1981-12-28 1982-11-30 Mead Johnson & Company 2-[4-[(4,4-Dialkyl-2,6-piperidinedion-1-yl)butyl]-1-piperazinyl]pyridines

Also Published As

Publication number Publication date
GB2174703B (en) 1988-10-26
AU593244B2 (en) 1990-02-08
HU195509B (en) 1988-05-30
FI85484B (fi) 1992-01-15
DK165745C (da) 1993-06-14
DE3615180C2 (de) 1996-03-07
JPH0753728B2 (ja) 1995-06-07
HUT43848A (en) 1987-12-28
GR861149B (en) 1986-09-09
IT1208607B (it) 1989-07-10
NL8601146A (nl) 1986-12-01
ES8900253A1 (es) 1989-05-16
ATA121486A (de) 1994-05-15
SE8602061D0 (sv) 1986-05-05
GB2174703A (en) 1986-11-12
ES8801250A1 (es) 1987-12-16
AU5679586A (en) 1986-11-13
LU86421A1 (fr) 1986-12-05
FI85484C (fi) 1992-04-27
ES554659A0 (es) 1987-12-16
FR2581385A1 (fr) 1986-11-07
CN86103071A (zh) 1987-03-18
GB8610810D0 (en) 1986-06-11
ES9000005A1 (es) 1989-11-01
ES557809A0 (es) 1988-09-01
ES557855A0 (es) 1989-05-16
PT82523A (en) 1986-06-01
ES8802149A1 (es) 1988-04-01
ZA862046B (en) 1986-11-26
SE465270B (sv) 1991-08-19
ES557757A0 (es) 1988-04-01
IE59201B1 (en) 1994-01-26
ES8900138A1 (es) 1989-01-16
ES557839A0 (es) 1989-01-16
FI861820A0 (fi) 1986-04-30
DK207186D0 (da) 1986-05-05
IE861193L (en) 1986-11-06
AT398572B (de) 1994-12-27
BE904724A (fr) 1986-11-05
MY100777A (en) 1991-02-14
SE8602061L (sv) 1986-11-07
FI861820A (fi) 1986-11-07
CH672787A5 (es) 1989-12-29
DK165745B (da) 1993-01-11
JPS61268681A (ja) 1986-11-28
DE3615180A1 (de) 1986-11-06
CN1017901B (zh) 1992-08-19
EG18206A (en) 1992-09-30
PT82523B (pt) 1988-10-14
ES8802614A1 (es) 1988-09-01
KR860009008A (ko) 1986-12-19
CA1278792C (en) 1991-01-08
FR2581385B1 (fr) 1991-10-04
DK207186A (da) 1986-11-07
IT8620313A0 (it) 1986-05-06

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