KR930019673A - β-락탐 유도체의 제조방법 및 그이 합성 중간체 - Google Patents
β-락탐 유도체의 제조방법 및 그이 합성 중간체Info
- Publication number
- KR930019673A KR930019673A KR1019930003328A KR930003328A KR930019673A KR 930019673 A KR930019673 A KR 930019673A KR 1019930003328 A KR1019930003328 A KR 1019930003328A KR 930003328 A KR930003328 A KR 930003328A KR 930019673 A KR930019673 A KR 930019673A
- Authority
- KR
- South Korea
- Prior art keywords
- group
- compound
- lower alkyl
- formula
- protected
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 238000000034 method Methods 0.000 title claims 6
- 239000000543 intermediate Substances 0.000 title 1
- 150000003952 β-lactams Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 claims abstract 17
- 125000000217 alkyl group Chemical group 0.000 claims abstract 12
- -1 beta -lactam compound Chemical class 0.000 claims abstract 10
- 239000003795 chemical substances by application Substances 0.000 claims abstract 8
- 150000002148 esters Chemical group 0.000 claims abstract 6
- 150000003839 salts Chemical class 0.000 claims abstract 6
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims abstract 5
- 125000001570 methylene group Chemical group [H]C([H])([*:1])[*:2] 0.000 claims abstract 5
- 125000003277 amino group Chemical group 0.000 claims abstract 4
- 229910052717 sulfur Inorganic materials 0.000 claims abstract 4
- 125000004434 sulfur atom Chemical group 0.000 claims abstract 4
- 230000003009 desulfurizing effect Effects 0.000 claims abstract 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims abstract 3
- 125000000962 organic group Chemical group 0.000 claims abstract 2
- 125000004430 oxygen atom Chemical group O* 0.000 claims abstract 2
- OJMIONKXNSYLSR-UHFFFAOYSA-N phosphorous acid Chemical compound OP(O)O OJMIONKXNSYLSR-UHFFFAOYSA-N 0.000 claims 6
- 229910052783 alkali metal Inorganic materials 0.000 claims 4
- 239000002585 base Substances 0.000 claims 4
- 125000000219 ethylidene group Chemical group [H]C(=[*])C([H])([H])[H] 0.000 claims 4
- 125000004066 1-hydroxyethyl group Chemical group [H]OC([H])([*])C([H])([H])[H] 0.000 claims 3
- 125000003282 alkyl amino group Chemical group 0.000 claims 3
- 239000007983 Tris buffer Substances 0.000 claims 2
- 150000003973 alkyl amines Chemical class 0.000 claims 2
- 150000004982 aromatic amines Chemical class 0.000 claims 2
- 238000001816 cooling Methods 0.000 claims 2
- 238000006477 desulfuration reaction Methods 0.000 claims 2
- 230000023556 desulfurization Effects 0.000 claims 2
- 230000001681 protective effect Effects 0.000 claims 2
- 125000006239 protecting group Chemical group 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G11—INFORMATION STORAGE
- G11B—INFORMATION STORAGE BASED ON RELATIVE MOVEMENT BETWEEN RECORD CARRIER AND TRANSDUCER
- G11B27/00—Editing; Indexing; Addressing; Timing or synchronising; Monitoring; Measuring tape travel
- G11B27/10—Indexing; Addressing; Timing or synchronising; Measuring tape travel
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/02—Preparation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/02—Preparation
- C07D477/04—Preparation by forming the ring or condensed ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D515/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D515/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D515/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Cephalosporin Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Hydrogenated Pyridines (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP4099023A JP2569455B2 (ja) | 1992-03-06 | 1992-03-06 | β−ラクタム誘導体の製法 |
| JP92-99023 | 1992-03-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR930019673A true KR930019673A (ko) | 1993-10-18 |
Family
ID=14235638
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019930003328A Abandoned KR930019673A (ko) | 1992-03-06 | 1993-03-05 | β-락탐 유도체의 제조방법 및 그이 합성 중간체 |
Country Status (12)
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0612749B1 (en) * | 1993-02-12 | 2003-05-02 | Suntory Limited | Method of desilylating silylether compounds |
| US6769128B1 (en) | 1995-06-07 | 2004-07-27 | United Video Properties, Inc. | Electronic television program guide schedule system and method with data feed access |
| CN1941863B (zh) | 1997-07-21 | 2011-06-29 | 骏升发展（美国）有限公司 | 在电子节目导视中向用户显示目标广告的方法 |
| EP1019347B1 (en) * | 1997-08-21 | 2003-03-19 | Florida State University | Method for the synthesis of taxanes |
| US6763522B1 (en) | 1998-06-30 | 2004-07-13 | Sony Corporation | System and method for a digital television electronic program guide |
| US6898762B2 (en) | 1998-08-21 | 2005-05-24 | United Video Properties, Inc. | Client-server electronic program guide |
| US20040002600A1 (en) * | 2002-06-20 | 2004-01-01 | Orchid Chemicals And Pharmaceuticals Limited | Process for the conversion of penam ring system to cepham ring system |
| WO2004035539A1 (ja) * | 2002-10-18 | 2004-04-29 | Meiji Seika Kaisha, Ltd. | カルバペネム類の製造方法およびその製造に用いられる中間体 |
| KR101059339B1 (ko) * | 2002-11-13 | 2011-08-24 | 가부시키가이샤 가네카 | 경구 투여용 카르바페넴 화합물의 제조 방법 |
| CN101172962B (zh) * | 2002-11-13 | 2010-09-08 | 株式会社钟化 | 经口给药用碳青霉素烯化合物的合成中间体 |
| WO2005005446A1 (ja) * | 2003-07-11 | 2005-01-20 | Nippon Soda Co., Ltd. | カルバペネム中間体の製造方法 |
| JP5016480B2 (ja) * | 2005-03-29 | 2012-09-05 | 株式会社カネカ | 結晶形態の１β−メチルカルバペネム中間体 |
| HU227443B1 (en) * | 2007-10-18 | 2011-06-28 | Pannon Egyetem | Multifunction-compatibilisation package of additives for plastic and rubber compositions |
| EP2326648B1 (en) * | 2008-07-30 | 2012-09-19 | Ranbaxy Laboratories Limited | Process for the preparation of carbapenem compounds |
| US8235923B2 (en) | 2008-09-30 | 2012-08-07 | Tyco Healthcare Group Lp | Compression device with removable portion |
| US9166714B2 (en) | 2009-09-11 | 2015-10-20 | Veveo, Inc. | Method of and system for presenting enriched video viewing analytics |
| WO2011048583A1 (en) | 2009-10-23 | 2011-04-28 | Ranbaxy Laboratories Limited | Process for the preparation of carbapenem compounds |
| US10695322B2 (en) | 2016-01-29 | 2020-06-30 | The Johns Hopkins University | Inhibitors of bacterial growth |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4547371A (en) * | 1983-04-18 | 1985-10-15 | Merck & Co., Inc. | Substituted cephalosporin sulfones as anti-inflammatory and anti-degenerative agents |
| US4782145A (en) * | 1986-06-02 | 1988-11-01 | Pfizer Inc. | Process for penem derivatives |
| CA2050255C (en) * | 1990-09-07 | 1997-02-04 | Tameo Iwasaki | 1-methylcarbapenem derivatives and process for preparation thereof |
-
1992
- 1992-03-06 JP JP4099023A patent/JP2569455B2/ja not_active Expired - Lifetime
-
1993
- 1993-02-17 US US08/018,407 patent/US5414081A/en not_active Expired - Fee Related
- 1993-02-17 CA CA002085540A patent/CA2085540A1/en not_active Abandoned
- 1993-02-26 ES ES93400506T patent/ES2119872T3/es not_active Expired - Lifetime
- 1993-02-26 AT AT93400506T patent/ATE168693T1/de active
- 1993-02-26 SG SG1996001266A patent/SG46231A1/en unknown
- 1993-02-26 DK DK93400506T patent/DK0559533T3/da active
- 1993-02-26 EP EP93400506A patent/EP0559533B1/en not_active Expired - Lifetime
- 1993-02-26 DE DE69319764T patent/DE69319764T2/de not_active Expired - Fee Related
- 1993-03-05 KR KR1019930003328A patent/KR930019673A/ko not_active Abandoned
- 1993-03-05 TW TW082101621A patent/TW249233B/zh active
-
1995
- 1995-04-07 US US08/393,395 patent/US5589592A/en not_active Expired - Fee Related
-
1998
- 1998-08-31 GR GR980401966T patent/GR3027788T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0559533B1 (en) | 1998-07-22 |
| DE69319764T2 (de) | 1998-11-26 |
| DE69319764D1 (de) | 1998-08-27 |
| US5589592A (en) | 1996-12-31 |
| DK0559533T3 (da) | 1998-12-14 |
| GR3027788T3 (en) | 1998-11-30 |
| TW249233B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1995-06-11 |
| SG46231A1 (en) | 1998-02-20 |
| US5414081A (en) | 1995-05-09 |
| JP2569455B2 (ja) | 1997-01-08 |
| ATE168693T1 (de) | 1998-08-15 |
| JPH05279367A (ja) | 1993-10-26 |
| EP0559533A1 (en) | 1993-09-08 |
| ES2119872T3 (es) | 1998-10-16 |
| CA2085540A1 (en) | 1993-09-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0109 | Patent application |
Patent event code: PA01091R01D Comment text: Patent Application Patent event date: 19930305 |
|
| PG1501 | Laying open of application | ||
| A201 | Request for examination | ||
| PA0201 | Request for examination |
Patent event code: PA02012R01D Patent event date: 19961113 Comment text: Request for Examination of Application Patent event code: PA02011R01I Patent event date: 19930305 Comment text: Patent Application |
|
| E902 | Notification of reason for refusal | ||
| PE0902 | Notice of grounds for rejection |
Comment text: Notification of reason for refusal Patent event date: 19981027 Patent event code: PE09021S01D |
|
| E701 | Decision to grant or registration of patent right | ||
| PE0701 | Decision of registration |
Patent event code: PE07011S01D Comment text: Decision to Grant Registration Patent event date: 19981231 |
|
| NORF | Unpaid initial registration fee | ||
| PC1904 | Unpaid initial registration fee |