KR930010016A - 단백질 분해효소 억제제인 사카린 유도체 - Google Patents

단백질 분해효소 억제제인 사카린 유도체 Download PDF

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Publication number
KR930010016A
KR930010016A KR1019920021438A KR920021438A KR930010016A KR 930010016 A KR930010016 A KR 930010016A KR 1019920021438 A KR1019920021438 A KR 1019920021438A KR 920021438 A KR920021438 A KR 920021438A KR 930010016 A KR930010016 A KR 930010016A
Authority
KR
South Korea
Prior art keywords
alkoxy
compound
alkyl
hlr
alkylamino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR1019920021438A
Other languages
English (en)
Korean (ko)
Inventor
폴 던랩 리챠드
조셉 뮤라 알버트
존 라스타 데니스
치맨랄 데사이 란지트
해밀톤 라티머 리
수브라마니암 챠크라파니
Original Assignee
폴 이. 듀퐁
스터링 윈드롭 인코포레이티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 폴 이. 듀퐁, 스터링 윈드롭 인코포레이티드 filed Critical 폴 이. 듀퐁
Publication of KR930010016A publication Critical patent/KR930010016A/ko
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
    • C07D275/04—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D275/06—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems with hetero atoms directly attached to the ring sulfur atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1019920021438A 1991-11-15 1992-11-14 단백질 분해효소 억제제인 사카린 유도체 Ceased KR930010016A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US79303591A 1991-11-15 1991-11-15
US793,035 1991-11-15

Publications (1)

Publication Number Publication Date
KR930010016A true KR930010016A (ko) 1993-06-21

Family

ID=25158888

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019920021438A Ceased KR930010016A (ko) 1991-11-15 1992-11-14 단백질 분해효소 억제제인 사카린 유도체

Country Status (15)

Country Link
EP (1) EP0542371A1 (cg-RX-API-DMAC7.html)
JP (1) JPH06122675A (cg-RX-API-DMAC7.html)
KR (1) KR930010016A (cg-RX-API-DMAC7.html)
AU (1) AU656027B2 (cg-RX-API-DMAC7.html)
CA (1) CA2082774A1 (cg-RX-API-DMAC7.html)
CZ (1) CZ338892A3 (cg-RX-API-DMAC7.html)
FI (1) FI925166A7 (cg-RX-API-DMAC7.html)
HU (2) HUT65694A (cg-RX-API-DMAC7.html)
IL (1) IL103747A (cg-RX-API-DMAC7.html)
MX (1) MX9206568A (cg-RX-API-DMAC7.html)
NO (1) NO302887B1 (cg-RX-API-DMAC7.html)
NZ (1) NZ245126A (cg-RX-API-DMAC7.html)
RU (1) RU2114835C1 (cg-RX-API-DMAC7.html)
SG (1) SG52778A1 (cg-RX-API-DMAC7.html)
TW (1) TW282463B (cg-RX-API-DMAC7.html)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5321217A (en) * 1990-07-18 1994-06-14 Otis Elevator Company Apparatus and method for controlling an elevator horizontal suspension
US5308938A (en) * 1990-07-18 1994-05-03 Otis Elevator Company Elevator active suspension system
US5322144A (en) * 1990-07-18 1994-06-21 Otis Elevator Company Active control of elevator platform
US5294757A (en) * 1990-07-18 1994-03-15 Otis Elevator Company Active vibration control system for an elevator, which reduces horizontal and rotational forces acting on the car
US5306818A (en) * 1990-11-01 1994-04-26 Sterling Winthrop Inc. Tetrahydro 2-saccharinylmerthyl aryl carboxylates
AU668694B2 (en) * 1991-12-19 1996-05-16 Sanofi-Synthelabo Saccharin derivative proteolytic enzyme inhibitors
US5378720A (en) * 1991-12-19 1995-01-03 Sterling Winthrop Inc. Saccharin derivative proteolytic enzyme inhibitors
TW226016B (cg-RX-API-DMAC7.html) * 1991-12-30 1994-07-01 Sterling Winthrop Inc
DE4427996A1 (de) * 1994-08-08 1996-02-15 Basf Ag Verfahren zur Herstellung von Saccharincarbonsäuren und -carbonsäureestern
DE19533643A1 (de) * 1995-09-12 1997-03-13 Nycomed Arzneimittel Gmbh Neue cyclische Derivate von Benzolsulfonamiden
WO2001017501A1 (en) * 1999-09-10 2001-03-15 The Procter & Gamble Company Enzyme inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ233521A (en) * 1989-05-04 1992-05-26 Sterling Drug Inc 2-substituted saccharin derivatives, preparation and pharmaceutical compositions thereof
US5236917A (en) * 1989-05-04 1993-08-17 Sterling Winthrop Inc. Saccharin derivatives useful as proteolytic enzyme inhibitors and compositions and method of use thereof
DE3917597A1 (de) * 1989-05-26 1990-11-29 Schering Ag Neue leukotrien-b(pfeil abwaerts)4(pfeil abwaerts)-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
AU642537B2 (en) * 1990-11-01 1993-10-21 Sanofi 2-saccharinylmethyl aryl carboxylates useful as proteolytic enzyme inhibitors and compositions and method of use thereof

Also Published As

Publication number Publication date
NO302887B1 (no) 1998-05-04
IL103747A (en) 1998-06-15
AU2605792A (en) 1993-05-20
CZ338892A3 (en) 1993-06-16
SG52778A1 (en) 1998-09-28
CA2082774A1 (en) 1993-05-16
NO924402D0 (no) 1992-11-13
HUT65694A (en) 1994-07-28
EP0542371A1 (en) 1993-05-19
TW282463B (cg-RX-API-DMAC7.html) 1996-08-01
FI925166L (fi) 1993-05-16
HU211664A9 (en) 1995-12-28
RU2114835C1 (ru) 1998-07-10
MX9206568A (es) 1993-05-01
JPH06122675A (ja) 1994-05-06
FI925166A0 (fi) 1992-11-13
HU9203561D0 (en) 1993-01-28
IL103747A0 (en) 1993-04-04
NZ245126A (en) 1996-01-26
NO924402L (no) 1993-05-18
FI925166A7 (fi) 1993-05-16
AU656027B2 (en) 1995-01-19

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PA0109 Patent application

Patent event code: PA01091R01D

Comment text: Patent Application

Patent event date: 19921114

PG1501 Laying open of application
N231 Notification of change of applicant
PN2301 Change of applicant

Patent event date: 19971008

Comment text: Notification of Change of Applicant

Patent event code: PN23011R01D

A201 Request for examination
PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 19971114

Comment text: Request for Examination of Application

Patent event code: PA02011R01I

Patent event date: 19921114

Comment text: Patent Application

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PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 19990821

Patent event code: PE09021S01D

E601 Decision to refuse application
PE0601 Decision on rejection of patent

Patent event date: 19991129

Comment text: Decision to Refuse Application

Patent event code: PE06012S01D

Patent event date: 19990821

Comment text: Notification of reason for refusal

Patent event code: PE06011S01I