KR920011486A - 항종양제 - Google Patents
항종양제 Download PDFInfo
- Publication number
- KR920011486A KR920011486A KR1019900019899A KR900019899A KR920011486A KR 920011486 A KR920011486 A KR 920011486A KR 1019900019899 A KR1019900019899 A KR 1019900019899A KR 900019899 A KR900019899 A KR 900019899A KR 920011486 A KR920011486 A KR 920011486A
- Authority
- KR
- South Korea
- Prior art keywords
- acidic
- quaternary salt
- composition
- methylenedioxybenzo
- phenanthridinium
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/056—Ortho-condensed systems with two or more oxygen atoms as ring hetero atoms in the oxygen-containing ring
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
내용 없음
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (9)
- 하기 구조식(A)의 7-히드록시-8-메톡시-5-메틸-2, 3-메틸렌디옥시벤조[C] 페난트리디늄 산성 4차염을 유효성분으로 함유하고 약제학적으로 허용되는 첨가제를 함유한 약제학적 조성물.(위의 식에서 X-는 산어성의 잔기이다.)
- 제1항에 있어서 산성 4차염이 할로게노산염인 조성물.
- 제1항에 있어서 산성 4차염이 염산염인 조성물.
- 제1항에 있어서 온혈동물의 악성종양의 성장억제, 전이억제 및 치료용 조성물.
- 악성종양의 치료, 성장억제 및 전이억제용 약제학적 조성물 제조를 위한 하기 구조식 (A)의 화합물의 용도.(위의 식에서 X-는 산성의 잔기이다)
- 의약용의 하기 구조식(A)의 7-히드록시-8-메톡시-5-메틸-2, 3-메틸렌디옥시벤조(C) 페난트리디늄산성 4차염(위의 식에서 X-는 산성의 잔기이다)
- 하기 구조식(A)의 7-히드록시-8-메톡시-5-메틸-2, 3-메틸렌디옥시벤조[C] 페난트리디늄 산성 4차염 유효투여량을 온혈동물에게 투여하여서 되는 종양이 있는 온혈동물의 종양의 성장억제, 전이억제 및 종양치료 방법.(위의 식에서 X-는 산성의 잔기이다)
- 제7항에 있어서 산성 4차염이 할로게노산염인 방법.
- 제7항에 있어서 산성 4차염이 염산염인 방법.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP1-321503 | 1989-12-13 | ||
JP1321503A JP2528370B2 (ja) | 1989-12-13 | 1989-12-13 | 抗腫瘍剤 |
JP01-321503 | 1989-12-13 |
Publications (2)
Publication Number | Publication Date |
---|---|
KR920011486A true KR920011486A (ko) | 1992-07-24 |
KR0159934B1 KR0159934B1 (ko) | 1998-12-01 |
Family
ID=18133292
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019900019899A KR0159934B1 (ko) | 1989-12-13 | 1990-12-05 | 항종양제 |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP0432630B1 (ko) |
JP (1) | JP2528370B2 (ko) |
KR (1) | KR0159934B1 (ko) |
AU (1) | AU629436B2 (ko) |
CA (1) | CA2032092A1 (ko) |
DE (1) | DE69007439T2 (ko) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2054569A1 (en) * | 1990-11-07 | 1992-05-08 | Masanobu Suzuki | Process for preparing benzo¬c|phenanthridinium derivatives, and novel compounds prepared by said process |
TW460464B (en) * | 1996-11-25 | 2001-10-21 | Nippon Kayaku Kk | Novel phenanthridinium derivative having an anti-tumor activity and pharmaceutical composition containing the same |
EP2968279A4 (en) * | 2013-03-15 | 2016-09-28 | Lixte Biotechnology Inc | SANGUINARIN ANALOG PPC2 HEMMER FOR CANCER TREATMENT |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4767626A (en) * | 1985-03-11 | 1988-08-30 | Theodore Cheng | Remedy for anemia and arthritis |
-
1989
- 1989-12-13 JP JP1321503A patent/JP2528370B2/ja not_active Expired - Lifetime
-
1990
- 1990-12-05 KR KR1019900019899A patent/KR0159934B1/ko not_active IP Right Cessation
- 1990-12-06 DE DE69007439T patent/DE69007439T2/de not_active Expired - Fee Related
- 1990-12-06 EP EP90123375A patent/EP0432630B1/en not_active Expired - Lifetime
- 1990-12-11 AU AU67945/90A patent/AU629436B2/en not_active Ceased
- 1990-12-12 CA CA002032092A patent/CA2032092A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP0432630B1 (en) | 1994-03-16 |
DE69007439D1 (de) | 1994-04-21 |
CA2032092A1 (en) | 1991-06-14 |
KR0159934B1 (ko) | 1998-12-01 |
JP2528370B2 (ja) | 1996-08-28 |
EP0432630A3 (en) | 1991-11-21 |
DE69007439T2 (de) | 1994-07-14 |
JPH03184916A (ja) | 1991-08-12 |
EP0432630A2 (en) | 1991-06-19 |
AU629436B2 (en) | 1992-10-01 |
AU6794590A (en) | 1991-06-20 |
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