KR920006910B1 - 데오필린-함유 서방성 제제의 제조방법 - Google Patents

데오필린-함유 서방성 제제의 제조방법 Download PDF

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Publication number
KR920006910B1
KR920006910B1 KR1019850009678A KR850009678A KR920006910B1 KR 920006910 B1 KR920006910 B1 KR 920006910B1 KR 1019850009678 A KR1019850009678 A KR 1019850009678A KR 850009678 A KR850009678 A KR 850009678A KR 920006910 B1 KR920006910 B1 KR 920006910B1
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KR
South Korea
Prior art keywords
deophylline
matrix
pellets
hours
sustained release
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
KR1019850009678A
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English (en)
Korean (ko)
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KR860004634A (ko
Inventor
베네딕트 제랄트
스타이니잔스 폴커
Original Assignee
비크 굴덴 롬베르그 케미쉐 파브리크 지엠비에이치
헤르베르트 주키, 헤르베르트 루프
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Publication date
Application filed by 비크 굴덴 롬베르그 케미쉐 파브리크 지엠비에이치, 헤르베르트 주키, 헤르베르트 루프 filed Critical 비크 굴덴 롬베르그 케미쉐 파브리크 지엠비에이치
Publication of KR860004634A publication Critical patent/KR860004634A/ko
Application granted granted Critical
Publication of KR920006910B1 publication Critical patent/KR920006910B1/ko
Expired legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5015—Organic compounds, e.g. fats, sugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Steroid Compounds (AREA)
KR1019850009678A 1984-12-21 1985-12-21 데오필린-함유 서방성 제제의 제조방법 Expired KR920006910B1 (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CH611184 1984-12-21
CH6111/84-6 1984-12-21
CH2683/85-5 1985-06-24
CH268385 1985-06-24

Publications (2)

Publication Number Publication Date
KR860004634A KR860004634A (ko) 1986-07-11
KR920006910B1 true KR920006910B1 (ko) 1992-08-22

Family

ID=25691137

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019850009678A Expired KR920006910B1 (ko) 1984-12-21 1985-12-21 데오필린-함유 서방성 제제의 제조방법

Country Status (20)

Country Link
US (1) US4803080A (https=)
EP (1) EP0185331B1 (https=)
KR (1) KR920006910B1 (https=)
CN (1) CN1008060B (https=)
AU (1) AU581274B2 (https=)
BG (1) BG60833B2 (https=)
CA (1) CA1261268A (https=)
CS (1) CS396391A3 (https=)
DE (1) DE3572924D1 (https=)
DK (1) DK164843C (https=)
ES (1) ES8704079A1 (https=)
FI (1) FI84782C (https=)
GR (1) GR853051B (https=)
HU (1) HU193359B (https=)
IE (1) IE58246B1 (https=)
IL (1) IL77322A (https=)
NO (1) NO171827C (https=)
NZ (1) NZ214534A (https=)
PT (1) PT81714B (https=)
SK (1) SK278868B6 (https=)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4753945A (en) * 1986-02-19 1988-06-28 Eye Research Institute Of Retina Foundation Stimulation of tear secretion with phosphodiesterase inhibitors
GB8628728D0 (en) * 1986-12-02 1987-01-07 Euro Celtique Sa Spheroids
EP0327295A3 (en) * 1988-02-01 1989-09-06 F.H. FAULDING & CO. LTD. Tetracycline dosage form
US5202128A (en) * 1989-01-06 1993-04-13 F. H. Faulding & Co. Limited Sustained release pharmaceutical composition
US5196203A (en) * 1989-01-06 1993-03-23 F. H. Faulding & Co. Limited Theophylline dosage form
DE3929864A1 (de) * 1989-09-08 1991-03-14 Nordmark Arzneimittel Gmbh Verfahren zur herstellung von theophyllin-pellets
GB2284761A (en) * 1993-12-03 1995-06-21 Euro Celtique Sa Prophylactic treatment of asthma
CN101111245A (zh) * 2005-01-27 2008-01-23 阿雷姆贝克有限公司 左乙拉西坦延长释放制剂
US20080014264A1 (en) * 2006-07-13 2008-01-17 Ucb, S.A. Novel pharmaceutical compositions comprising levetiracetam
RU2631597C2 (ru) 2011-07-15 2017-09-25 Нусерт Сайенсиз, Инк. Композиции и способы модулирования метаболических путей
SG10201709195TA (en) 2012-11-13 2017-12-28 Nusirt Sciences Inc Compositions and methods for increasing energy metabolism
WO2014113404A1 (en) 2013-01-15 2014-07-24 Nusirt Sciences, Inc. Treating pulmonary conditions
CN105228627B (zh) 2013-03-15 2018-07-13 纽斯尔特科学公司 亮氨酸和烟酸降低脂质水平
KR20160119863A (ko) 2014-02-27 2016-10-14 뉴서트 사이언시스, 인크. 간 지방증의 감소 또는 예방을 위한 조성물 및 방법
JP6826730B2 (ja) * 2015-04-16 2021-02-10 学校法人 関西大学 抗氷核活性剤
CN106176682A (zh) * 2016-08-30 2016-12-07 铜陵翔宇商贸有限公司 茶碱缓释制胶囊剂及其制备方法
WO2020067887A1 (en) 2018-09-24 2020-04-02 Erasmus University Medical Center Rotterdam Specific inhibition of janus kinase 3 (jak3) for modulating anti-tumor immune responses
GB202001237D0 (en) * 2020-01-29 2020-03-11 Sisteks D O O Granular pharmaceutical product for oral administration from a pre-filled straw and method of manufacturing such pharmaceutical product

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1091289B (de) * 1956-01-25 1960-10-20 Hans Lowey Verfahren zur Herstellung einer oral anzuwendenden Arzneiform mit verlaengerter Wirkungsdauer
DE2336218C3 (de) * 1973-07-17 1985-11-14 Byk Gulden Lomberg Chemische Fabrik Gmbh, 7750 Konstanz Orale Arzneiform
US4587118A (en) * 1981-07-15 1986-05-06 Key Pharmaceuticals, Inc. Dry sustained release theophylline oral formulation
DE3278491D1 (en) * 1981-07-15 1988-06-23 Key Pharma Sustained release theophyline
US4704284A (en) * 1982-08-12 1987-11-03 Pfizer Inc. Long-acting matrix tablet formulations
IE55745B1 (en) * 1983-04-06 1991-01-02 Elan Corp Plc Sustained absorption pharmaceutical composition
DE3435325A1 (de) * 1983-04-09 1986-04-17 Nikken Chemicals Co., Ltd., Tokio/Tokyo Langzeitwirkende theophyllin-tablette und verfahren zu deren herstellung

Also Published As

Publication number Publication date
NO171827C (no) 1993-05-12
EP0185331A1 (de) 1986-06-25
BG60833B2 (bg) 1996-04-30
PT81714B (pt) 1988-04-21
FI84782C (fi) 1992-01-27
CA1261268A (en) 1989-09-26
IL77322A (en) 1990-07-12
FI84782B (fi) 1991-10-15
AU5161885A (en) 1986-07-17
DK600485A (da) 1986-06-22
SK278868B6 (sk) 1998-04-08
AU581274B2 (en) 1989-02-16
GR853051B (https=) 1986-02-03
DE3572924D1 (en) 1989-10-19
FI854973L (fi) 1986-06-22
CN1008060B (zh) 1990-05-23
DK600485D0 (da) 1985-12-20
NO171827B (no) 1993-02-01
FI854973A0 (fi) 1985-12-16
NO855215L (no) 1986-06-23
US4803080A (en) 1989-02-07
HUT40334A (en) 1986-12-28
IE853107L (en) 1986-06-21
IE58246B1 (en) 1993-08-11
EP0185331B1 (de) 1989-09-13
DK164843C (da) 1993-01-11
DK164843B (da) 1992-08-31
HU193359B (en) 1987-09-28
CS396391A3 (en) 1992-06-17
CN85109688A (zh) 1986-06-10
ES550291A0 (es) 1987-04-01
KR860004634A (ko) 1986-07-11
PT81714A (de) 1986-01-01
ES8704079A1 (es) 1987-04-01
NZ214534A (en) 1988-08-30

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