KR910700260A - 호중구-활성화 펩티드-2 - Google Patents

호중구-활성화 펩티드-2

Info

Publication number
KR910700260A
KR910700260A KR1019900701733A KR900701733A KR910700260A KR 910700260 A KR910700260 A KR 910700260A KR 1019900701733 A KR1019900701733 A KR 1019900701733A KR 900701733 A KR900701733 A KR 900701733A KR 910700260 A KR910700260 A KR 910700260A
Authority
KR
South Korea
Prior art keywords
fragment
derivative
neutrophil
functional variant
activating factor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
KR1019900701733A
Other languages
English (en)
Korean (ko)
Inventor
바기올리니 마르코
죤 클레멧슨 케네스
월츠 알프레드
Original Assignee
예안 크라메트, 한스 루돌프 하우스
산도즈 아게
바기올리니 마르코
테오도르 코헤르 인스티튜트
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB888828728A external-priority patent/GB8828728D0/en
Priority claimed from GB898909681A external-priority patent/GB8909681D0/en
Application filed by 예안 크라메트, 한스 루돌프 하우스, 산도즈 아게, 바기올리니 마르코, 테오도르 코헤르 인스티튜트 filed Critical 예안 크라메트, 한스 루돌프 하우스
Publication of KR910700260A publication Critical patent/KR910700260A/ko
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/521Chemokines
    • C07K14/522Alpha-chemokines, e.g. NAP-2, ENA-78, GRO-alpha/MGSA/NAP-3, GRO-beta/MIP-2alpha, GRO-gamma/MIP-2beta, IP-10, GCP-2, MIG, PBSF, PF-4, KC
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/54Interleukins [IL]
    • C07K14/5421IL-8
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
KR1019900701733A 1988-12-08 1989-11-17 호중구-활성화 펩티드-2 Withdrawn KR910700260A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB8828728 1988-12-08
GB888828728A GB8828728D0 (en) 1988-12-08 1988-12-08 Neutrophil-stimulating activity i
GB898909681A GB8909681D0 (en) 1989-04-27 1989-04-27 Neutrophil-stimulating activity 1
GB8909681 1989-04-27
PCT/EP1989/001389 WO1990006321A1 (en) 1988-12-08 1989-11-17 Neutrophil-activating peptide-2

Publications (1)

Publication Number Publication Date
KR910700260A true KR910700260A (ko) 1991-03-14

Family

ID=26294713

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019900701733A Withdrawn KR910700260A (ko) 1988-12-08 1989-11-17 호중구-활성화 펩티드-2

Country Status (19)

Country Link
US (1) US5759533A (enExample)
JP (1) JP3051160B2 (enExample)
KR (1) KR910700260A (enExample)
AU (1) AU634508B2 (enExample)
BE (1) BE1003636A4 (enExample)
CA (1) CA2004685A1 (enExample)
CH (1) CH681625A5 (enExample)
DK (1) DK188690A (enExample)
ES (1) ES2047458A6 (enExample)
FI (1) FI903931A0 (enExample)
FR (1) FR2640142B1 (enExample)
GB (1) GB2231872B (enExample)
GR (1) GR1000455B (enExample)
IL (1) IL92557A0 (enExample)
NL (1) NL8921262A (enExample)
NZ (1) NZ231652A (enExample)
PT (1) PT92509A (enExample)
SE (1) SE9002589L (enExample)
WO (1) WO1990006321A1 (enExample)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3051160B2 (ja) * 1988-12-08 2000-06-12 ノバルティス・アクチエンゲゼルシャフト 好中球活性化ペプチド‐2
US6673893B1 (en) 1990-02-01 2004-01-06 University Of South Florida Leukocyte derived growth factor 2
CA2075196A1 (en) * 1990-02-01 1991-08-02 Gary R. Grotendorst Leukocyte-derived growth factor
WO1993001826A1 (en) * 1991-07-19 1993-02-04 East Carolina University Method of treating asthma
WO1993009794A1 (en) * 1991-11-15 1993-05-27 University Of Pennsylvania Suppression of megakaryocytopoiesis by neutrophil activating peptide-2
EP0677106A4 (en) * 1993-01-07 1998-12-09 Univ South Florida GROWTH FACTORS MADE OF LEUKOCYTEN.
US5578569A (en) * 1993-03-12 1996-11-26 Tam; Cherk S. Method of increasing bone growth
US5786327A (en) 1993-03-12 1998-07-28 Gensci Regeneration Sciences Inc. Bone stimulating factor, methods of isolating same, and methods of increasing bone growth comprising administering same
US6458349B1 (en) 1995-06-02 2002-10-01 Human Genome Sciences, Inc. Chemokine β-4 polypeptides
US6391589B1 (en) 1994-08-23 2002-05-21 Human Genome Sciences, Inc. Human chemokine beta-10 mutant polypeptides
US6174995B1 (en) 1994-08-23 2001-01-16 Haodong Li Human chemokines, CKβ4 and CKβ10/MCP-4
US5912232A (en) * 1994-09-23 1999-06-15 Board Of Regents Of The University Of Nebraska Anti-inflammatory polypeptide antagonists of human I1-8
US6352973B1 (en) 1995-06-07 2002-03-05 Osteopharm Inc. Bone stimulating factor
US6117839A (en) * 1995-06-07 2000-09-12 Gensci Regeneration Sciences, Inc. Bone stimulating factor
US5880094A (en) * 1995-06-07 1999-03-09 Osteopharm Limited Polypeptides that stimulate bone growth
US6693081B2 (en) * 1995-09-26 2004-02-17 Osteopharm Inc. Bone stimulating factor
US6290948B1 (en) * 1996-05-14 2001-09-18 Smithkline Beecham Corporation Method of treating sepsis and ARDS using chamohine beta-10
US6838435B1 (en) 1997-09-25 2005-01-04 Academisch Ziekenhuis Bij De Universiteit Van Amsterdam Isolated and recombinant antimicrobial peptides thrombocidin-1 (TC-1) and thrombocidin-2(TC-2) or variants thereof
GB9807721D0 (en) * 1998-04-08 1998-06-10 Chiron Spa Antigen
CA2723031C (en) * 2000-03-07 2014-05-20 Japan Tobacco Inc. Polypeptides having neutrophil stimulating activity
US6815421B1 (en) 2001-03-22 2004-11-09 Osteopharm Inc. Polypeptides for use in ameliorating effects of aging in mammals
EP1534752B1 (en) 2002-05-01 2011-08-03 Human Genome Sciences, Inc. Antibodies that specifically bind to chemokine beta-4
US7177246B2 (en) * 2003-09-12 2007-02-13 Hewlett-Packard Development Company, L.P. Optical disk drive focusing apparatus using sum signal
PH12013500990A1 (en) 2010-11-19 2022-11-23 Eisai R&D Man Co Ltd Neutralizing anti-ccl20 antibodies

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4897348A (en) * 1983-08-25 1990-01-30 Sri International Recombinant materials and methods for producing human connective tissue-activating peptide-III and analogs thereof
DE3737703A1 (de) * 1987-11-06 1989-05-18 Ferring Arzneimittel Gmbh Neutrophilen aktivierendes polypeptid, verfahren zu dessen herstellung sowie dessen verwendung als arzneimittel und diagnostikum
US5026639A (en) * 1988-01-14 1991-06-25 Nippon Mining Company, Limited Method to improve mRNA translation and use thereof for production of platelet factor-4
JP3051160B2 (ja) * 1988-12-08 2000-06-12 ノバルティス・アクチエンゲゼルシャフト 好中球活性化ペプチド‐2

Also Published As

Publication number Publication date
SE9002589D0 (sv) 1990-08-07
BE1003636A4 (fr) 1992-05-12
GR890100810A (en) 1991-03-15
AU4655689A (en) 1990-06-26
FI903931A7 (fi) 1990-08-08
IL92557A0 (en) 1990-08-31
PT92509A (pt) 1990-06-29
CA2004685A1 (en) 1990-06-08
US5759533A (en) 1998-06-02
FR2640142B1 (fr) 1994-09-23
JPH03503767A (ja) 1991-08-22
WO1990006321A1 (en) 1990-06-14
FI903931A0 (fi) 1990-08-08
ES2047458A6 (es) 1994-02-16
DK188690D0 (da) 1990-08-07
AU634508B2 (en) 1993-02-25
DK188690A (da) 1990-08-07
GB2231872B (en) 1992-07-22
NL8921262A (nl) 1990-11-01
NZ231652A (en) 1993-02-25
FR2640142A1 (fr) 1990-06-15
SE9002589L (sv) 1990-08-07
GR1000455B (el) 1992-07-30
CH681625A5 (enExample) 1993-04-30
GB9011468D0 (en) 1990-08-29
GB2231872A (en) 1990-11-28
JP3051160B2 (ja) 2000-06-12

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Legal Events

Date Code Title Description
PA0109 Patent application

Patent event code: PA01091R01D

Comment text: Patent Application

Patent event date: 19900807

PG1501 Laying open of application
PC1203 Withdrawal of no request for examination
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid