KR910000138A - 약제학적 조성물 - Google Patents

약제학적 조성물 Download PDF

Info

Publication number
KR910000138A
KR910000138A KR1019890007835A KR890007835A KR910000138A KR 910000138 A KR910000138 A KR 910000138A KR 1019890007835 A KR1019890007835 A KR 1019890007835A KR 890007835 A KR890007835 A KR 890007835A KR 910000138 A KR910000138 A KR 910000138A
Authority
KR
South Korea
Prior art keywords
ibuprofen
salt
magnesium
solution
complex
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR1019890007835A
Other languages
English (en)
Korean (ko)
Inventor
헌터 크리스토퍼
야유 데이비드
Original Assignee
피터 로스 밀리간
레키트 앤드 콜맨 프로덕트 리미티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 피터 로스 밀리간, 레키트 앤드 콜맨 프로덕트 리미티드 filed Critical 피터 로스 밀리간
Publication of KR910000138A publication Critical patent/KR910000138A/ko
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Nanotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
KR1019890007835A 1988-06-09 1989-06-08 약제학적 조성물 Ceased KR910000138A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB888813682A GB8813682D0 (en) 1988-06-09 1988-06-09 Pharmaceutical compositions
GB8813682.5 1988-06-09

Publications (1)

Publication Number Publication Date
KR910000138A true KR910000138A (ko) 1991-01-29

Family

ID=10638367

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019890007835A Ceased KR910000138A (ko) 1988-06-09 1989-06-08 약제학적 조성물

Country Status (18)

Country Link
US (1) US5019563A (enExample)
EP (1) EP0346006B1 (enExample)
JP (1) JPH02243649A (enExample)
KR (1) KR910000138A (enExample)
AT (1) ATE83924T1 (enExample)
AU (1) AU609988B2 (enExample)
CA (1) CA1320192C (enExample)
DE (1) DE68904121T2 (enExample)
DK (1) DK280789A (enExample)
ES (1) ES2052914T3 (enExample)
FI (1) FI93692C (enExample)
GB (2) GB8813682D0 (enExample)
GR (1) GR3006729T3 (enExample)
IE (1) IE61616B1 (enExample)
NO (1) NO175039B (enExample)
NZ (1) NZ229204A (enExample)
PT (1) PT90760B (enExample)
ZA (1) ZA893913B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100730393B1 (ko) * 2005-06-10 2007-06-20 한국콜마 주식회사 이부프로펜 및 아르기닌을 함유하는 약학 조성물의제조방법

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3827974A1 (de) * 1988-08-18 1990-02-22 Boehringer Mannheim Gmbh Kombinationspraeparate von proteinkinase-c-inhibitoren mit lipiden, lipid-analoga, cytostatica oder inhibitoren von phospholipasen
MY106598A (en) * 1988-08-31 1995-06-30 Australian Commercial Res & Development Ltd Compositions and methods for drug delivery and chromatography.
DE3922441A1 (de) * 1989-07-07 1991-01-17 Pharmatrans Sanaq Ag Ibuprofen- und s-(+)-ibuprofen-zubereitungen und verfahren zu ihrer herstellung
US5262179A (en) * 1989-09-13 1993-11-16 Nicholas Kiwi Pty Ltd. Non-effervescent ibuprofen compositions
FR2660195B1 (fr) * 1990-03-28 1994-10-07 Crinex Sa Laboratoires Composition pharmaceutique a macher, antiinflammatoire et/ou analgesique.
ATE143805T1 (de) * 1991-03-22 1996-10-15 Merck & Co Inc Arzneizubereitung mit hohem gehalt an ibuprofenlysinat
EP1004318A3 (en) * 1991-06-21 2002-08-07 Takeda Chemical Industries, Ltd. Cyclodextrin composition
US5321014A (en) * 1991-06-28 1994-06-14 The United States Of America As Represented By The Department Of Health And Human Services Molecular encapsulation and delivery of alkenes alkynes and long chain alkanes, to living mammalian cells
IT1255007B (it) * 1991-07-01 1995-10-11 Altergon Sa Sale solubile dell'ibuprofen c0n n-(2-idrossietil) pirrolidina e composizioni farmaceutiche che li contengono.
GB9207990D0 (en) * 1992-04-10 1992-05-27 Smithkline Beecham Plc Pharmaceutical composition
IT1272149B (it) * 1993-03-26 1997-06-11 Zambon Spa Composizione farmeceutiche ad attivita' analgesica
HU210922B (en) * 1993-05-24 1995-09-28 Europharmaceuticals Sa Nimesulide alkali salt cyclodextrin inclusion complexes their preparation and pharmaceutical compositions containing them
CN1088600C (zh) * 1993-07-31 2002-08-07 史密丝克莱恩比彻姆有限公司 布洛芬－β－环糊精配合物的用途
US5582351A (en) * 1993-08-09 1996-12-10 Tsau; Josef Convenient to use aspartame and method of making
US5866162A (en) * 1993-08-10 1999-02-02 Smithkline Beecham P.L.C. Pharmaceutical composition containing a drug/β-cyclodextrin complex in combination with an acid-base couple
GB9316580D0 (en) * 1993-08-10 1993-09-29 Smithkline Beecham Plc Pharmaceutical composition
CZ306394A3 (en) * 1993-12-14 1995-08-16 Lilly Co Eli Aqueous solution of inclusion complex of benzothiophene derivative with water-soluble cyclodextrins, process of its preparation and a pharmaceutical composition containing thereof
US5646131A (en) * 1994-02-22 1997-07-08 The Arab Company For Drug Industries And Medical Applicances (Acdima) Method for solubilizing drugs using cyclodextrins and carboxylic acids
EP0760680A1 (en) * 1994-05-27 1997-03-12 Farmarc Nederland Bv Pharmaceutical composition
BE1008307A3 (fr) * 1994-06-16 1996-04-02 Europharmaceuticals Sa Sel de nimesulide hydrosoluble, solution aqueuse le contenant, sa preparation et son utilisation.
ZA959469B (en) * 1994-11-15 1996-05-15 South African Druggists Ltd Pharmaceutical composition
US5942501A (en) * 1996-08-16 1999-08-24 Collaborative Laboratories, Inc. Cyclodextrin derivative complex
IT1301966B1 (it) 1998-07-30 2000-07-20 Zambon Spa Composizioni farmaceutiche ad attivita' analgesica
US6287603B1 (en) * 1999-09-16 2001-09-11 Nestec S.A. Cyclodextrin flavor delivery systems
ES2171110B1 (es) * 2000-03-03 2003-06-16 Aplicaciones Farmacodinamicas Composicion farmaceutica a base de ibuprofeno y procedimiento para su preparacion.
US7704975B2 (en) * 2000-12-19 2010-04-27 Cephalon, Inc. Modafinil compound and cyclodextrin mixtures
US7141555B2 (en) * 2000-12-19 2006-11-28 Cephalon, Inc. Modafinil compound and cyclodextrin mixtures
US6727286B2 (en) 2001-11-02 2004-04-27 Cumberland Pharmaceuticals Inc. Pharmaceutical composition of 2-(4-isobutylphenyl) propionic acid
KR100451485B1 (ko) * 2002-03-28 2004-10-06 주식회사종근당 푸마질롤 유도체 또는 그 염의 포접 화합물, 및 이를포함하는 약제학적 조성물
US20060233873A1 (en) * 2003-01-24 2006-10-19 Julien Meissonnier Dispersion of taste masked crystals or granules of active substances, chewable soft capsules filled with said dispersion, and process for preparing same
FR2850275B1 (fr) * 2003-01-24 2005-04-08 Scherer Technologies Inc R P Capsules molles a macher contenant une substance active a gout masque
US20050137262A1 (en) * 2003-12-22 2005-06-23 Hu Patrick C. Highly concentrated pourable aqueous solutions of potassium ibuprofen, their preparation and their uses
MXPA06014185A (es) * 2004-06-07 2007-04-16 Strides Arcolab Ltd Composicion farmaceutica que contiene una solucion estable y clara de medicamento anti-inflmatorio en capsulas de gelatina blanda, y proceso para producirlo.
GB2423710A (en) * 2005-03-01 2006-09-06 Boots Healthcare Int Ltd Lozenge production process
EP1942877A4 (en) * 2005-11-02 2011-09-14 Teikoku Pharma Usa Inc ORGANOLEPTICALLY ACCEPTABLE ORAL DOSAGE FORMS OF IBUPROFEN, MANUFACTURING METHOD AND APPLICATION
MX2008011823A (es) * 2006-03-16 2008-10-31 Novartis Ag Forma de dosificacion solida que contiene un agente activo de sabor encubierto.
FR2914187B1 (fr) * 2007-03-28 2011-01-21 Pf Medicament Complexes d'ibuprofene, de cyclodextrines et d'agents ternaires, et leurs utilisations en pharmaceutique.
US20110144207A1 (en) * 2008-08-14 2011-06-16 Shasun Chemicals And Drugs Limited Aryl alkyl carboxylic acid salts, process for preparation and dosage forms
EP2238973A1 (en) 2009-04-07 2010-10-13 Cephalon France Lyophilized preparations of proteasome inhibitors
US20120101159A1 (en) * 2009-04-27 2012-04-26 Laboratorio De Aplicaciones Farmacodinamicas, S.A. Ibuprofen lysinate oral suspension
ES2347754B8 (es) * 2009-04-27 2012-06-04 Laboratorio De Aplicaciones Farmacodinamicas, S.A Suspension oral de lisinato de ibuprofeno
DK2253329T3 (en) * 2009-04-27 2017-01-16 Laboratorio De Aplicaciones Farm S A Oral ibuprofen lysinate suspension.
TWI542344B (zh) * 2009-06-22 2016-07-21 惠氏有限責任公司 異丁苯丙酸鈉錠及製備包含異丁苯丙酸鈉之醫藥組合物之方法
CN101978955A (zh) * 2010-11-05 2011-02-23 航天中心医院 右旋布洛芬氨基酸盐片剂及其制备方法
US10098964B2 (en) 2015-03-12 2018-10-16 The Board Of Trustees Of The University Of Illinois Inclusion complexes and methods for making the same
CN114588107B (zh) * 2022-04-06 2023-04-18 河北一品生物医药有限公司 一种布洛芬赖氨酸盐注射液及其制备方法
GR1010732B (el) * 2023-06-02 2024-07-25 Ιουλια Κλεωνος Τσετη Φαρμακευτικη συνθεση ιβουπροφαινης και παρακεταμολης για απο του στοματος χορηγηση
CN116688154B (zh) * 2023-07-10 2026-04-17 山东新华制药股份有限公司 一种包合物药品的生产方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5646837A (en) * 1979-09-27 1981-04-28 Kowa Yakuhin Kogyo Kk Preparation of ibuprofen clathrate compound
DE3346123A1 (de) * 1983-12-21 1985-06-27 Janssen Pharmaceutica, N.V., Beerse Pharmazeutische praeparate von in wasser schwerloeslichen oder instabilen arzneistoffen und verfahren zu ihrer herstellung
US4795698A (en) * 1985-10-04 1989-01-03 Immunicon Corporation Magnetic-polymer particles
GB8613688D0 (en) * 1986-06-05 1986-07-09 Euro Celtique Sa Pharmaceutical composition
CA1298290C (en) * 1987-01-09 1992-03-31 Herand M. Markarian Solution ibuprofen complexes, compositions and processes for preparing the same

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100730393B1 (ko) * 2005-06-10 2007-06-20 한국콜마 주식회사 이부프로펜 및 아르기닌을 함유하는 약학 조성물의제조방법

Also Published As

Publication number Publication date
PT90760A (pt) 1989-12-29
NO175039C (enExample) 1994-08-24
NO175039B (no) 1994-05-16
NZ229204A (en) 1992-03-26
GB8911938D0 (en) 1989-07-12
GR3006729T3 (enExample) 1993-06-30
ZA893913B (en) 1990-02-28
ES2052914T3 (es) 1994-07-16
EP0346006A1 (en) 1989-12-13
US5019563A (en) 1991-05-28
FI892780L (fi) 1989-12-10
IE891757L (en) 1989-12-09
GB2219585A (en) 1989-12-13
DE68904121T2 (de) 1993-05-06
AU609988B2 (en) 1991-05-09
ATE83924T1 (de) 1993-01-15
IE61616B1 (en) 1994-11-16
FI892780A0 (fi) 1989-06-07
GB2219585B (en) 1991-11-06
DE68904121D1 (de) 1993-02-11
FI93692C (fi) 1995-05-26
NO892340L (no) 1989-12-11
EP0346006B1 (en) 1992-12-30
NO892340D0 (no) 1989-06-07
AU3492789A (en) 1989-12-14
PT90760B (pt) 1994-10-31
CA1320192C (en) 1993-07-13
DK280789A (da) 1989-12-12
JPH02243649A (ja) 1990-09-27
GB8813682D0 (en) 1988-07-13
FI93692B (fi) 1995-02-15
DK280789D0 (da) 1989-06-08

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PA0109 Patent application

Patent event code: PA01091R01D

Comment text: Patent Application

Patent event date: 19890608

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PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 19940330

Comment text: Request for Examination of Application

Patent event code: PA02011R01I

Patent event date: 19890608

Comment text: Patent Application

E902 Notification of reason for refusal
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PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 19970730

Patent event code: PE09021S01D

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Patent event date: 19970730

Comment text: Notification of Change of Applicant

Patent event code: PN23011R01D

E601 Decision to refuse application
PE0601 Decision on rejection of patent

Patent event date: 19971027

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Patent event code: PE06012S01D

Patent event date: 19970730

Comment text: Notification of reason for refusal

Patent event code: PE06011S01I