KR900700081A - 부양성 경구용 투약 치료 기제(浮揚性 經口用 投藥 治療 基劑) - Google Patents

부양성 경구용 투약 치료 기제(浮揚性 經口用 投藥 治療 基劑)

Info

Publication number
KR900700081A
KR900700081A KR1019890701835A KR890701835A KR900700081A KR 900700081 A KR900700081 A KR 900700081A KR 1019890701835 A KR1019890701835 A KR 1019890701835A KR 890701835 A KR890701835 A KR 890701835A KR 900700081 A KR900700081 A KR 900700081A
Authority
KR
South Korea
Prior art keywords
therapeutic
base according
structural element
substrate
active ingredient
Prior art date
Application number
KR1019890701835A
Other languages
English (en)
Inventor
밀러 발터
안데르스 에드자르트
Original Assignee
프랑크 베커 쥬리겐 마쓰
엘테에스 로오만 데라피-지스테메 게엠베하 운트 콤파니 카케
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6346718&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR900700081(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 프랑크 베커 쥬리겐 마쓰, 엘테에스 로오만 데라피-지스테메 게엠베하 운트 콤파니 카케 filed Critical 프랑크 베커 쥬리겐 마쓰
Publication of KR900700081A publication Critical patent/KR900700081A/ko

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0065—Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

내용 없음

Description

부양성 경구용 투약 치료 기제(浮揚性 經口用 投藥 治療 基劑)
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제1도는 본 발명의 치료기재의 단면도이고, 제2도는 본 발명의 다층구성 정제의 투시도이고, 제3도는 정심(錠芯) : tablet core)이 미세공의 구조적 요소로 이루어진 정제 모양의 치료기재를 보이는 투시도.

Claims (16)

  1. 포말 또는 공동체(hollow body)와 같은 강실(carty)이 있는 1이상의 구조적 요소로 이루어짐을 특징으로 하는 부양성 경구용 치료기재.
  2. 제1항에 있어서, 구조적 요소(12)가 기재 내에 균일하게 분포되어 있는 치료기재.
  3. 제1항에 있어서, 구조적 요소가 필름 형상인 치료기재.
  4. 제1항에 있어서, 구조적 요소가 유효성분을 함유하는 치료기재.
  5. 제1항 내지 제4항의 어느 한항에 있어서, 구조적 요소가 아래(가)의 중합체, (나)의 공중합체 또는 폴리실록산을 함유함을 특징으로 하는 기재.
    (가) 중합체 : 폴리에틸렌. 폴리프로필렌, 폴리아미드, 폴리스티렌, 폴리에스테르, 폴리아크릴레이트, 폴리테트라 플루오로에틸렌, 염화폴리비닐 또는 염화 폴리비닐리덴.
    (나) 공중합체 : 단량체 및 이와 결합한 상기 중합체로 이루어진 것.
  6. 제1항 내지 제4항의 어느한 항에 있어서, 구조적 요소가 유리 또는 세라믹 물질 같은 무기 물질을 함유하는 치료 기재.
  7. 제1항 내지 제6항의 어느한 항에 있어서, 유효성분을 운반하는 조절격막(7)이 구성된 치료기재.
  8. 제1항 내지 제7항의 어느한 항에 있어서, 유효성분을 함유하는 열용융 물질(1)이 함유되고, 그 안에 구조적 요소가 구성된 치료기재.
  9. 제1항 내지 제7항의 어느 한 항에 있어서, 구조적 요소가 유효성분을 함유하는 형상물(shaped article)안에 구성되어 있는 치료기재.
  10. 제9항에 있어서, 형상물이 수성 겔(hydro gel)이거나, 위액과 접촉 형성하는 수성겔인 치료기재.
  11. 제1항에 있어서, 중심부가 강실 비율이 높은 구조적 요소로 이루어지고 구조적 요소는 유효성분 함유 피복층이나 유효성분을 보유한 부양성 부기재로 구성된 치료기재.
  12. 제11항에 있어서, 부양성 부기재가 생리적 조건하에 가용성인 캡슐내에 구성된 치료기재.
  13. 제11항에 또는 제12항에 있어서, 부양성 부기재가 결속재(binder) 0과 결합하여 형상물을 형성하고, 위액 및/또는 장액 접촉하에 결속재가 용해하는 동안 일탈(release)할수 있는 치료기재.
  14. 제1항 내지 제13항의 어느 한항에 있어서, 다층 피복(multicoating)형태이거나, 1이상의 피복층인 부양성 구조적 요소로 구성된 치료기재.
  15. 제3항, 제4항 또는 제14항에 있어서 투여전에 함께 접거나 말아서, 투약된 위장내에서 퍼지거나 풀려질수 있는 치료기재.
  16. 제1항 내지 제15항의 어느 한항에 있어서, 생리적 조건하에 전부 또는 일부가 분해될수 있는 치료기재.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019890701835A 1988-02-05 1989-01-10 부양성 경구용 투약 치료 기제(浮揚性 經口用 投藥 治療 基劑) KR900700081A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DEP3803482.4 1988-02-05
DE3803482A DE3803482A1 (de) 1988-02-05 1988-02-05 Schwimmfaehiges orales therapeutisches system
PCT/DE1989/000008 WO1989006956A1 (en) 1988-02-05 1989-01-10 Floating system for oral therapy

Publications (1)

Publication Number Publication Date
KR900700081A true KR900700081A (ko) 1990-08-11

Family

ID=6346718

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019890701835A KR900700081A (ko) 1988-02-05 1989-01-10 부양성 경구용 투약 치료 기제(浮揚性 經口用 投藥 治療 基劑)

Country Status (25)

Country Link
US (1) US5626876A (ko)
EP (1) EP0326816A1 (ko)
JP (1) JP2929548B2 (ko)
KR (1) KR900700081A (ko)
AU (1) AU637043B2 (ko)
CA (1) CA1325366C (ko)
CZ (1) CZ288441B6 (ko)
DD (1) DD278720A5 (ko)
DE (1) DE3803482A1 (ko)
DK (1) DK489189D0 (ko)
FI (1) FI894688A (ko)
HR (1) HRP920835A2 (ko)
HU (1) HU215971B (ko)
IE (1) IE890135L (ko)
IL (1) IL89105A (ko)
MY (1) MY104821A (ko)
NO (1) NO301688B1 (ko)
NZ (1) NZ227859A (ko)
PL (1) PL165146B1 (ko)
PT (1) PT89618A (ko)
SI (1) SI8910254A (ko)
SK (1) SK281011B6 (ko)
WO (1) WO1989006956A1 (ko)
YU (1) YU25489A (ko)
ZA (1) ZA89506B (ko)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995005809A1 (fr) * 1993-08-20 1995-03-02 Nippon Shinyaku Co., Ltd. Preparation restant dans l'estomac, forme moulee gonflee, et procede de preparation
DE4406424A1 (de) * 1994-02-28 1995-08-31 Bayer Ag Expandierbare Arzneiformen
GB9718664D0 (en) * 1997-09-04 1997-11-05 Scherer Corp R P Improvements in or relating to capsules
IN186245B (ko) 1997-09-19 2001-07-14 Ranbaxy Lab Ltd
DE19822278A1 (de) * 1998-05-18 1999-12-02 Lohmann Therapie Syst Lts Vorrichtung zur kontrollierten Freisetzung von Wirkstoff im Gastrointestinaltrakt mit verzögerter Pyloruspassage
US6351665B1 (en) 1999-05-07 2002-02-26 Kenneth L Koch Method and apparatus for evaluating myoelectric signals and identifying artifact
EP1066836A1 (en) * 1999-06-11 2001-01-10 Sensus, part of Coöperatie COSUN U.A. Filler/binder hollow particles for tablets
FR2797185B1 (fr) * 1999-08-06 2001-10-26 Galenix Dev Composition pharmaceutique flottante comprenant une phase active et une phase non active
DE10014588A1 (de) 2000-03-27 2001-10-04 Basf Ag Wirkstoffhaltige Schwimmformen enthaltend Polyvinylacetat und Polyvinylpyrrolidon, deren Verwendung und Herstellung
DE10032456A1 (de) 2000-07-04 2002-01-31 Lohmann Therapie Syst Lts Schnell zerfallende Darreichungsform zur Freisetzung von Wirkstoffen im Mundraum oder in Körperhöhlen
AU2005202270B2 (en) * 2000-07-04 2006-10-26 Lts Lohmann Therapie-Systeme Ag Rapidly Disintegrating Dosage form For Releasing Nicotine in the Oral Cavity or in Body Cavities
EP1245227A1 (en) * 2001-03-31 2002-10-02 Jagotec Ag A pharmaceutical tablet system that floats in the stomach for programmed release of active substance and process of producing buoyant material contained in same
GB0214013D0 (en) * 2002-06-18 2002-07-31 Euro Celtique Sa Pharmaceutical product
DE102004023069A1 (de) 2004-05-11 2005-12-08 Bayer Healthcare Ag Neue Darreichungsformen des PDE 5-Inhibitors Vardenafil
CN1853728A (zh) * 2005-04-19 2006-11-01 上海天博生物科技有限公司 一种改善药物或营养物口服吸收的方法、配方及其应用
AT505225A1 (de) 2007-04-26 2008-11-15 Sanochemia Pharmazeutika Ag 0erfahren zur herstellung von hoch reinem 2,4'-dimethyl-3-piperidino-propiophenon (tolperison), dieses enthaltende pharmazeutische zusammensetzungen, sowie tolperison enthaltende wirkstoffformulierungen
DE102007026037A1 (de) 2007-06-04 2008-12-11 Lts Lohmann Therapie-Systeme Ag Gastroretentives System mit Alginat-Körper
EP2133071A1 (en) * 2008-06-09 2009-12-16 Université de la Méditerranée Process for making gastroretentive dosage forms
US20100249423A1 (en) * 2009-03-09 2010-09-30 Sanochemia Pharmazeutika Ag Tolperisone controlled release tablet
FR2945947B1 (fr) 2009-05-29 2011-07-29 Flamel Tech Sa Compositions pharmaceutiques flottantes a liberation controlee
FR2945945B1 (fr) * 2009-05-29 2011-07-29 Flamel Tech Sa Procede de preparation de particules creuses et leurs applications
JP5594484B2 (ja) * 2009-07-06 2014-09-24 杏林製薬株式会社 中空構造を有する錠剤
EP2444064A1 (en) * 2010-10-22 2012-04-25 Meliatys Process for making multiparticulate gastroretentive dosage forms
AU2012322323B2 (en) 2011-10-11 2016-04-21 Sun Pharmaceutical Industries Limited A gastroretentive dosage system and process of preparation thereof
WO2015060814A1 (en) * 2013-10-22 2015-04-30 Capso Vision Inc. System and method for capsule device with multiple phases of density
CA3018011A1 (en) * 2016-03-18 2017-09-21 Grunenthal Gmbh Floating pharmaceutical dosage form
WO2018228440A1 (zh) * 2017-06-14 2018-12-20 江苏恒瑞医药股份有限公司 一种非布司他控释组合物及其制备方法
WO2019069108A1 (en) * 2017-10-04 2019-04-11 Debreceni Egyetem SOLID GALENIC FORM, MOLDED, GASTRIC RETENTION AND EXTENDED RELEASE AND METHOD OF PREPARING THE SAME
JP2023516370A (ja) * 2020-03-02 2023-04-19 クラフト ヘルス プライベート リミテッド 持続的薬物放出のための経口剤形
US11529310B2 (en) 2020-12-08 2022-12-20 Ruminant Biotech Corp Limited Devices and methods for delivery of substances to animals

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5512411B2 (ko) * 1974-03-12 1980-04-02
GB2077585A (en) * 1980-06-12 1981-12-23 Standard Telephones Cables Ltd Sustained-release bodies of soluble glass tubules
US4764380A (en) * 1982-03-22 1988-08-16 Alza Corporation Drug delivery system comprising a volume increasing matrix containing a plurality of tiny pills
US4451260A (en) * 1982-03-26 1984-05-29 Minnesota Mining And Manufacturing Company Sustained release oral medicinal delivery device
DE3214667C2 (de) * 1982-04-21 1985-07-18 Akzo Gmbh, 5600 Wuppertal Zusammengesetzter Körper für die Langzeitabgabe von Wirkstoffen
US4539256A (en) * 1982-09-09 1985-09-03 Minnesota Mining And Manufacturing Co. Microporous sheet material, method of making and articles made therewith
US4818542A (en) * 1983-11-14 1989-04-04 The University Of Kentucky Research Foundation Porous microspheres for drug delivery and methods for making same
US4865789A (en) * 1983-11-14 1989-09-12 Akzo Nv Method for making porous structures
EP0162492B1 (en) * 1984-04-11 1989-08-02 Thiemann Arzneimittel GmbH Dosage units for controlled release of active material
PL149493B1 (en) * 1985-04-12 1990-02-28 Method of obtaining a tablet capable to buoy over surface of gastric juice
GB8518301D0 (en) * 1985-07-19 1985-08-29 Fujisawa Pharmaceutical Co Hydrodynamically explosive systems
WO1987004077A1 (en) * 1986-01-03 1987-07-16 The University Of Melbourne Gastro-oesophageal reflux composition
DE3612212A1 (de) * 1986-04-11 1987-10-15 Basf Ag Verfahren zur herstellung von festen pharmazeutischen formen
DE3630603A1 (de) * 1986-09-09 1988-03-10 Desitin Arzneimittel Gmbh Darreichungs- und dosierungsform fuer arzneimittelwirkstoffe, reagentien oder dergleichen sowie verfahren zu deren herstellung
US4830860A (en) * 1986-10-30 1989-05-16 Pfizer Inc. Stressed polymeric device for controlled release of a substance to an ambient environment

Also Published As

Publication number Publication date
HU215971B (hu) 1999-03-29
IL89105A (en) 1993-02-21
NZ227859A (en) 1992-01-29
JPH02503087A (ja) 1990-09-27
SK49389A3 (en) 2000-10-09
NO893838D0 (no) 1989-09-27
HU890731D0 (ko) 1990-03-28
HUT54490A (en) 1991-03-28
PT89618A (pt) 1989-10-04
MY104821A (en) 1994-06-30
CA1325366C (en) 1993-12-21
AU637043B2 (en) 1993-05-20
CZ49389A3 (cs) 1999-08-11
SK281011B6 (sk) 2000-10-09
PL277506A1 (en) 1989-10-30
JP2929548B2 (ja) 1999-08-03
US5626876A (en) 1997-05-06
NO301688B1 (no) 1997-12-01
CZ288441B6 (en) 2001-06-13
DD278720A5 (de) 1990-05-16
SI8910254A (en) 1997-02-28
HRP920835A2 (en) 1994-10-31
WO1989006956A1 (en) 1989-08-10
IE890135L (en) 1989-08-05
IL89105A0 (en) 1989-08-15
FI894688A0 (fi) 1989-10-03
YU25489A (en) 1991-04-30
FI894688A (fi) 1989-10-03
DK489189A (da) 1989-10-04
DE3803482A1 (de) 1989-08-17
AU2914389A (en) 1989-08-25
DK489189D0 (da) 1989-10-04
EP0326816A1 (de) 1989-08-09
NO893838L (no) 1989-09-27
ZA89506B (en) 1990-02-28
PL165146B1 (pl) 1994-11-30

Similar Documents

Publication Publication Date Title
KR900700081A (ko) 부양성 경구용 투약 치료 기제(浮揚性 經口用 投藥 治療 基劑)
EP0090560B1 (en) Sustained release oral medicinal delivery device
KR910004178A (ko) 위내 보유 장치
AU670410B2 (en) Transdermal drug delivery device using a membrane-protected microporous membrane to achieve delayed onset
USRE39588E1 (en) Transdermal drug delivery device
ES2051698T3 (es) Granulos destinados a permanecer en el estomago.
PT795324E (pt) Comprimido farmaceutico caracterizado por apresentar um elevado aumento volumerico quando colocado em contacto com fluidos biologicos
CA2145513A1 (en) Pharmaceutical Tablet Capable of Liberating One or More Drugs at Different Release Rates
NZ260630A (en) Tri-layer sustained release tablet coated with impermeable film apart from a small area on one face
JP2005526757A5 (ko)
WO1993003696A1 (en) Transdermal drug delivery device using an unfilled microporous membrane to achieve delayed onset
KR950007808A (ko) 약물투여용 의료용구
KR910018045A (ko) 흡입에 의해 약제를 투여하기 위한 운반 기구
CA2391393A1 (en) Film preparation for biphasic release of pharmacologically active or other substances
CA2344672A1 (en) Expandable gastroretentive therapy system having a prolonged gastric residence time
JP2020510086A (ja) 活性分子を送達するためのマイクロセルシステム
ATE195418T1 (de) Kombiniertes antipyretisches und analgetisches arzneimittel
JPS59118529U (ja) 薬剤含有積層フイルム
WO2005084255A2 (en) Aspirin transdermal patch
KR870009728A (ko) 조절된 방출속도로 화학물질을 투여하기 위한 적충 구조물
JP3124971B2 (ja) 長時間持続性の経皮投与用消炎鎮痛剤
JP2758002B2 (ja) 貼付剤
JPH0278616A (ja) 貼付剤
GB1473076A (ko)
JPH02143925U (ko)

Legal Events

Date Code Title Description
A201 Request for examination
E902 Notification of reason for refusal
E601 Decision to refuse application