KR900013961A - 기억력 및 학습력 증강 또는 인식 또는 정신장해 치료용 d-시클로세린 및 d-알라닌 함유 조성물 - Google Patents

기억력 및 학습력 증강 또는 인식 또는 정신장해 치료용 d-시클로세린 및 d-알라닌 함유 조성물 Download PDF

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Publication number
KR900013961A
KR900013961A KR1019900003482A KR900003482A KR900013961A KR 900013961 A KR900013961 A KR 900013961A KR 1019900003482 A KR1019900003482 A KR 1019900003482A KR 900003482 A KR900003482 A KR 900003482A KR 900013961 A KR900013961 A KR 900013961A
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KR
South Korea
Prior art keywords
therapeutically effective
effective amount
alanine
cycloserine
ratio
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR1019900003482A
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English (en)
Korean (ko)
Inventor
에이.코르디 알렉시스
알.잔스 미카엘
Original Assignee
파울 디. 마투카이티스
지.디.썰 앤드 캄파니
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 파울 디. 마투카이티스, 지.디.썰 앤드 캄파니 filed Critical 파울 디. 마투카이티스
Publication of KR900013961A publication Critical patent/KR900013961A/ko
Ceased legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Detergent Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
KR1019900003482A 1989-03-15 1990-03-15 기억력 및 학습력 증강 또는 인식 또는 정신장해 치료용 d-시클로세린 및 d-알라닌 함유 조성물 Ceased KR900013961A (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US32427989A 1989-03-15 1989-03-15
US324,279 1989-03-25
US07/473,241 US5061721A (en) 1989-03-15 1990-02-06 Composition containing d-cycloserine and d-alanine for memory and learning enhancement or treatment of a cognitive or psychotic disorder
US473,241 1990-02-06

Publications (1)

Publication Number Publication Date
KR900013961A true KR900013961A (ko) 1990-10-22

Family

ID=26984373

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019900003482A Ceased KR900013961A (ko) 1989-03-15 1990-03-15 기억력 및 학습력 증강 또는 인식 또는 정신장해 치료용 d-시클로세린 및 d-알라닌 함유 조성물

Country Status (17)

Country Link
US (1) US5061721A (enExample)
EP (1) EP0387867B1 (enExample)
JP (1) JP2963720B2 (enExample)
KR (1) KR900013961A (enExample)
AT (1) ATE88890T1 (enExample)
AU (1) AU624917B2 (enExample)
CA (1) CA2010635C (enExample)
DE (1) DE69001503T2 (enExample)
DK (1) DK0387867T3 (enExample)
ES (1) ES2055197T3 (enExample)
FI (1) FI901289A7 (enExample)
GR (1) GR3008225T3 (enExample)
IE (1) IE64130B1 (enExample)
IL (1) IL93562A (enExample)
NO (1) NO901198L (enExample)
NZ (1) NZ232809A (enExample)
PT (1) PT93424B (enExample)

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US6551993B1 (en) * 1999-08-16 2003-04-22 Thomas Jefferson University Partial agonists at the glycine modulatory site of the NMDA receptor for treating cognitive dysfunction
US6399574B1 (en) 2000-03-22 2002-06-04 University Of Utah Research Foundation Use of conantokins
US20040122090A1 (en) * 2001-12-07 2004-06-24 Lipton Stuart A. Methods for treating neuropsychiatric disorders with nmda receptor antagonists
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CA2442798A1 (en) 2001-04-02 2002-10-10 Panorama Research, Inc. Antioxidant nitroxides and nitrones as therapeutic agents
CA2446074C (en) * 2001-05-02 2011-09-06 Blanchette Rockefeller Neurosciences Institute Carbonic anhydrase activators for enhancing learning and memory
CA2478808A1 (en) * 2002-03-15 2003-09-25 H. Lundbeck A/S Use of asc-1 inhibitors to treat neurological and psychiatric disorders
AU2004251636B2 (en) 2003-05-27 2006-11-09 Merz Pharma Gmbh & Co. Kgaa Combination of an NMDA receptor antagonist and a selective serotonin reuptake inhibitor for the treatment of depression and other mood disorders
US7244764B2 (en) 2003-06-23 2007-07-17 Neurochem (International) Limited Methods and compositions for treating amyloid-related diseases
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WO2005065308A2 (en) 2003-12-29 2005-07-21 Jason Mcdevitt Compositions and methods to treat recurrent medical conditions
TW201206425A (en) 2004-05-18 2012-02-16 Brni Neurosciences Inst Treatment of depressive disorders
US7619007B2 (en) * 2004-11-23 2009-11-17 Adamas Pharmaceuticals, Inc. Method and composition for administering an NMDA receptor antagonist to a subject
CA2900876A1 (en) 2004-12-22 2006-08-17 Bhi Limited Partnership Methods and compositions for treating amyloid-related diseases
BRPI0607017B8 (pt) 2005-04-06 2021-05-25 Adamas Pharmaceuticals Inc composição farmacêutica compreendendo memantina e donezepil, e seu uso para o tratamento de condições relacionadas ao snc
TW200716088A (en) 2005-04-15 2007-05-01 Neurochem Int Ltd Formulations and methods for treating amyloidosis
PT2089417E (pt) 2006-10-12 2015-04-14 Bhi Ltd Partnership Métodos, compostos, composições e veículos para administrar o ácido 3-amino-1-propanossulfónico
WO2008124814A2 (en) * 2007-04-10 2008-10-16 Mcdevitt Jason P Sublingual formulations of d-cycloserine and methods of using same
EP2331571B1 (en) 2008-09-18 2015-08-26 Northwestern University Nmda receptor modulators and uses thereof
WO2010099217A1 (en) 2009-02-25 2010-09-02 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
US8951968B2 (en) 2009-10-05 2015-02-10 Northwestern University Methods of treating depression and other related diseases
TWI544923B (zh) * 2009-12-29 2016-08-11 何應瑞 用於治療神經退化性疾病之醫藥組合物
RU2566821C2 (ru) 2010-02-11 2015-10-27 Нортвестерн Юниверсити Модулятор nmda-рецептора со стабилизированной вторичной структурой и его применение
KR101692275B1 (ko) 2010-02-11 2017-01-04 노오쓰웨스턴 유니버시티 2차 구조 안정화된 nmda 수용체 조절제 및 그의 용도
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WO2018026798A1 (en) 2016-08-01 2018-02-08 Aptinyx Inc. Spiro-lactam nmda modulators and methods of using same
ES2973283T3 (es) 2016-08-01 2024-06-19 Tenacia Biotechnology Hong Kong Co Ltd Moduladores de receptores de NMDA espirolactámicos y usos de los mismos
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Also Published As

Publication number Publication date
CA2010635A1 (en) 1990-09-15
ATE88890T1 (de) 1993-05-15
ES2055197T3 (es) 1994-08-16
DE69001503D1 (de) 1993-06-09
GR3008225T3 (enExample) 1993-09-30
IE900921L (en) 1990-09-15
IL93562A0 (en) 1990-11-29
IE64130B1 (en) 1995-07-12
NO901198L (no) 1990-09-17
AU5073490A (en) 1990-09-20
PT93424B (pt) 1996-08-30
DE69001503T2 (de) 1993-09-09
FI901289A0 (fi) 1990-03-15
NO901198D0 (no) 1990-03-14
NZ232809A (en) 1992-05-26
PT93424A (pt) 1990-11-07
EP0387867B1 (en) 1993-05-05
CA2010635C (en) 2001-03-06
DK0387867T3 (da) 1993-06-01
AU624917B2 (en) 1992-06-25
US5061721A (en) 1991-10-29
JP2963720B2 (ja) 1999-10-18
EP0387867A1 (en) 1990-09-19
IL93562A (en) 1996-01-31
JPH03148221A (ja) 1991-06-25
FI901289A7 (fi) 1990-09-16

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