KR900009596A - N-피리디닐-9h-카바졸-9-아민, 이의 제조방법 및 이의 약제로서의 용도 - Google Patents

N-피리디닐-9h-카바졸-9-아민, 이의 제조방법 및 이의 약제로서의 용도 Download PDF

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Publication number
KR900009596A
KR900009596A KR1019890019472A KR890019472A KR900009596A KR 900009596 A KR900009596 A KR 900009596A KR 1019890019472 A KR1019890019472 A KR 1019890019472A KR 890019472 A KR890019472 A KR 890019472A KR 900009596 A KR900009596 A KR 900009596A
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KR
South Korea
Prior art keywords
compound
lower alkyl
hydrogen
formula
halogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
KR1019890019472A
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English (en)
Korean (ko)
Inventor
챨스 에프랜드 리챠드
토마스 클레인 죠셉
데이비스 래리
에드워드 올센 고돈
Original Assignee
원본미기재
훽스트-러셀 파마슈티칼즈 인코포레이티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 원본미기재, 훽스트-러셀 파마슈티칼즈 인코포레이티드 filed Critical 원본미기재
Publication of KR900009596A publication Critical patent/KR900009596A/ko
Withdrawn legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/61—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Hydrogenated Pyridines (AREA)
  • Indole Compounds (AREA)
KR1019890019472A 1988-12-27 1989-12-26 N-피리디닐-9h-카바졸-9-아민, 이의 제조방법 및 이의 약제로서의 용도 Withdrawn KR900009596A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/289,887 US4868190A (en) 1988-12-27 1988-12-27 N-pyridinyl-9H-carbazol-9-amines
US289887 1988-12-27

Publications (1)

Publication Number Publication Date
KR900009596A true KR900009596A (ko) 1990-07-05

Family

ID=23113557

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019890019472A Withdrawn KR900009596A (ko) 1988-12-27 1989-12-26 N-피리디닐-9h-카바졸-9-아민, 이의 제조방법 및 이의 약제로서의 용도

Country Status (19)

Country Link
US (1) US4868190A (enExample)
EP (1) EP0376155B1 (enExample)
JP (1) JPH0725749B2 (enExample)
KR (1) KR900009596A (enExample)
AT (1) ATE79118T1 (enExample)
AU (1) AU623205B2 (enExample)
CA (1) CA2006529C (enExample)
DE (1) DE68902386T2 (enExample)
DK (1) DK662189A (enExample)
ES (1) ES2044043T3 (enExample)
FI (1) FI896243A7 (enExample)
GR (1) GR3006140T3 (enExample)
IE (1) IE894175L (enExample)
IL (1) IL92867A0 (enExample)
NO (1) NO895222L (enExample)
NZ (1) NZ231943A (enExample)
PH (1) PH27122A (enExample)
PT (1) PT92696A (enExample)
ZA (1) ZA899904B (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4916135A (en) * 1989-05-08 1990-04-10 Hoechst Roussel Pharmaceuticals Inc. N-heteroaryl-4-quinolinamines
DE69016531T2 (de) * 1989-08-02 1995-07-06 Hoechst Roussel Pharma 2,3-Dihydro-1-(pyridinylamino)-indole, Verfahren zu ihrer Herstellung und ihre Anwendung als Arzneimittel.
US5179099A (en) * 1989-08-02 1993-01-12 Hoechst-Roussel Pharmaceuticals Incorporated 2,3-dihydro-1-(pyridinylamino)-indoles
US4994472A (en) * 1989-08-02 1991-02-19 Hoechst-Roussel Pharmaceuticals Incorporated 1-(pyridinylamino)-2-pyrrolidinones as pain relievers
US4983608A (en) * 1989-09-05 1991-01-08 Hoechst-Roussell Pharmaceuticals, Inc. N-substituted-4-pyrimidinamines and pyrimidinediamines
MX9800774A (es) * 1995-07-27 1998-04-30 Hoechst Marion Roussel Inc Uso de n-(pirrol-1-il)piridinaminas no sustituidas y sustituidas como agentes anticonvulsivos.
US5776955A (en) * 1995-07-27 1998-07-07 Hoechst Marion Roussel, Inc. Use of unsubstituted and substituted n-(pyrrol-1-yl)pyridinamines as anticonvulsant agents
ZA989365B (en) * 1997-10-15 1999-04-15 Boehringer Mannheim Pharm Corp Preparation for treating alzheimer's disease
US20020107283A1 (en) * 2000-07-21 2002-08-08 Codd Ellen E. Carbamate compounds for use in preventing or treating neuropathic pain and cluster and migraine headache-associated pain

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH475982A (de) * 1966-11-16 1969-07-31 Wander Ag Dr A Verfahren zur Herstellung von Carbazolderivaten
EP0073849A1 (en) * 1981-09-03 1983-03-16 Schering Corporation Novel phenyl-1,2,3,4-tetrahydrocarbazoles, their preparation and pharmaceutical compositions containing them
US4752610A (en) * 1985-12-04 1988-06-21 Hoechst-Roussel Pharmaceuticals Inc. N-(pyrrol-1-yl)pyridinamines having memory enhancing properties
US4792562A (en) * 1985-12-04 1988-12-20 Hoechst-Roussel Pharmaceuticals, Inc. N-(pyrrol-1-yl)pyridinamines having memory enhancing activity
ATE115143T1 (de) * 1987-04-24 1994-12-15 Hoechst Roussel Pharma N-(pyridinyl)-1h-indol-1-amine, verfahren zu deren herstellung und ihre verwendung als arzneimittel.
US4806554A (en) * 1988-01-11 1989-02-21 Hoechst-Roussel Pharmaceuticals, Inc. Pyrazol and indazolpyridinamines
US4916135A (en) * 1989-05-08 1990-04-10 Hoechst Roussel Pharmaceuticals Inc. N-heteroaryl-4-quinolinamines
DE69016531T2 (de) * 1989-08-02 1995-07-06 Hoechst Roussel Pharma 2,3-Dihydro-1-(pyridinylamino)-indole, Verfahren zu ihrer Herstellung und ihre Anwendung als Arzneimittel.
US5006537A (en) * 1989-08-02 1991-04-09 Hoechst-Roussel Pharmaceuticals, Inc. 1,3-dihydro-1-(pyridinylamino)-2H-indol-2-ones

Also Published As

Publication number Publication date
DK662189D0 (da) 1989-12-22
PH27122A (en) 1993-03-16
PT92696A (pt) 1990-06-29
GR3006140T3 (enExample) 1993-06-21
CA2006529C (en) 1999-08-10
EP0376155B1 (en) 1992-08-05
CA2006529A1 (en) 1990-06-27
NO895222L (no) 1990-06-28
JPH0725749B2 (ja) 1995-03-22
ATE79118T1 (de) 1992-08-15
US4868190A (en) 1989-09-19
ZA899904B (en) 1991-02-27
JPH02247173A (ja) 1990-10-02
AU623205B2 (en) 1992-05-07
ES2044043T3 (es) 1994-01-01
NZ231943A (en) 1992-06-25
DK662189A (da) 1990-06-28
EP0376155A1 (en) 1990-07-04
IL92867A0 (en) 1990-09-17
DE68902386D1 (de) 1992-09-10
DE68902386T2 (de) 1993-02-11
FI896243A0 (fi) 1989-12-22
NO895222D0 (no) 1989-12-22
AU4720389A (en) 1990-07-05
FI896243A7 (fi) 1990-06-28
IE894175L (en) 1990-06-27

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Legal Events

Date Code Title Description
PA0109 Patent application

Patent event code: PA01091R01D

Comment text: Patent Application

Patent event date: 19891226

PG1501 Laying open of application
PC1203 Withdrawal of no request for examination
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid