KR890700663A - 소마토트로핀 암호화 cDNA, 발현 벡터 및 숙주 - Google Patents

소마토트로핀 암호화 cDNA, 발현 벡터 및 숙주

Info

Publication number
KR890700663A
KR890700663A KR1019880701313A KR880701313A KR890700663A KR 890700663 A KR890700663 A KR 890700663A KR 1019880701313 A KR1019880701313 A KR 1019880701313A KR 880701313 A KR880701313 A KR 880701313A KR 890700663 A KR890700663 A KR 890700663A
Authority
KR
South Korea
Prior art keywords
somatotropin
host
expression vector
encoding cdna
somatotropins
Prior art date
Application number
KR1019880701313A
Other languages
English (en)
Other versions
KR960016704B1 (ko
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of KR890700663A publication Critical patent/KR890700663A/ko
Application granted granted Critical
Publication of KR960016704B1 publication Critical patent/KR960016704B1/ko

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • C07K14/592—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH] at least 1 amino acid in D-form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/61—Growth hormone [GH], i.e. somatotropin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Reproductive Health (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Compression, Expansion, Code Conversion, And Decoders (AREA)
  • Radio Relay Systems (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Cosmetics (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Detergent Compositions (AREA)
  • Compression Or Coding Systems Of Tv Signals (AREA)
  • Two-Way Televisions, Distribution Of Moving Picture Or The Like (AREA)
KR1019880701313A 1987-02-19 1988-02-09 소마토트로핀 암호화 cDNA, 발현 벡터 및 숙주 KR960016704B1 (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US1629487A 1987-02-19 1987-02-19
US016,294 1987-02-19
PCT/US1988/000328 WO1988006186A2 (en) 1987-02-19 1988-01-27 cDNAs ENCODING SOMATOTROPIN, EXPRESSION VECTORS AND HOSTS
USPCTUS88/00328 1988-02-09

Publications (2)

Publication Number Publication Date
KR890700663A true KR890700663A (ko) 1989-04-26
KR960016704B1 KR960016704B1 (ko) 1996-12-20

Family

ID=21776383

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019880701313A KR960016704B1 (ko) 1987-02-19 1988-02-09 소마토트로핀 암호화 cDNA, 발현 벡터 및 숙주

Country Status (9)

Country Link
EP (1) EP0418219B1 (ko)
JP (1) JP2580303B2 (ko)
KR (1) KR960016704B1 (ko)
AT (1) ATE107696T1 (ko)
AU (1) AU615432B2 (ko)
DE (1) DE3850410T2 (ko)
DK (1) DK580188D0 (ko)
HK (1) HK65497A (ko)
WO (1) WO1988006186A2 (ko)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5104806A (en) * 1987-03-12 1992-04-14 Amgen, Inc. Porcine growth hormone analogs encoding dna
EP0398983A1 (en) * 1988-01-27 1990-11-28 The Upjohn Company Expression vectors
US5268284A (en) * 1988-03-11 1993-12-07 The Upjohn Company Ribosome binding site
AU4315089A (en) * 1988-11-04 1990-05-28 Upjohn Company, The Somatotropin expression using a serratia promoter
ES2069277T3 (es) * 1990-01-31 1995-05-01 Upjohn Co Cepa ral-4, util para la produccion de proteinas y peptidos pequeños.

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ201918A (en) * 1981-09-18 1987-04-30 Genentech Inc N-terminal methionyl analogues of bovine growth hormone
EP0111814A3 (en) * 1982-12-16 1985-08-14 Mgi Pharma, Inc. The cloning and expression of nucleotide sequences encoding bovine growth hormone
GB8308236D0 (en) * 1983-03-25 1983-05-05 Celltech Ltd Dna vectors
JPS6011557A (ja) * 1983-04-19 1985-01-21 ジエネツクス・コ−ポレイシヨン クロ−ンヒツジ成長ホルモン遺伝子
BG49718A3 (en) * 1983-07-15 1992-01-15 Bio Technology General Corp Method for preparing of polypeptid with superoxiddismutasne activitty
US4710473A (en) * 1983-08-10 1987-12-01 Amgen, Inc. DNA plasmids
AU557486B2 (en) * 1984-01-27 1986-12-24 Monsanto Company Composition for improved bovine feeding and milk production
EP0159123B1 (en) * 1984-03-06 1992-01-15 Eli Lilly And Company Vectors for expressing bovine growth hormone derivatives
US4758512A (en) * 1984-03-06 1988-07-19 President And Fellows Of Harvard College Hosts and methods for producing recombinant products in high yields
EP0355460B1 (en) * 1988-08-24 2000-12-27 American Cyanamid Company Stabilization of somatotropins by modification of cysteine residues utilizing site directed mutagenesis or chemical derivatization

Also Published As

Publication number Publication date
DE3850410D1 (de) 1994-07-28
WO1988006186A2 (en) 1988-08-25
WO1988006186A3 (en) 1988-11-03
AU615432B2 (en) 1991-10-03
HK65497A (en) 1997-05-23
AU1363988A (en) 1988-09-14
DK580188A (da) 1988-10-18
EP0418219A1 (en) 1991-03-27
EP0418219B1 (en) 1994-06-22
DK580188D0 (da) 1988-10-18
DE3850410T2 (de) 1994-10-27
KR960016704B1 (ko) 1996-12-20
JPH02502245A (ja) 1990-07-26
JP2580303B2 (ja) 1997-02-12
ATE107696T1 (de) 1994-07-15

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