DE3850410D1 - cDNS KODIEREND FÜR SOMATOTROPIN, EXPRESSIONSVEKTOREN UND -WIRTE. - Google Patents

cDNS KODIEREND FÜR SOMATOTROPIN, EXPRESSIONSVEKTOREN UND -WIRTE.

Info

Publication number
DE3850410D1
DE3850410D1 DE3850410T DE3850410T DE3850410D1 DE 3850410 D1 DE3850410 D1 DE 3850410D1 DE 3850410 T DE3850410 T DE 3850410T DE 3850410 T DE3850410 T DE 3850410T DE 3850410 D1 DE3850410 D1 DE 3850410D1
Authority
DE
Germany
Prior art keywords
innkeepers
somatotropin
expression vectors
cdna coding
vectors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE3850410T
Other languages
English (en)
Other versions
DE3850410T2 (de
Inventor
Che-Shen Tomich
Eric Olson
John Mott
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of DE3850410D1 publication Critical patent/DE3850410D1/de
Application granted granted Critical
Publication of DE3850410T2 publication Critical patent/DE3850410T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • C07K14/592—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH] at least 1 amino acid in D-form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/61—Growth hormone [GH], i.e. somatotropin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Plant Pathology (AREA)
  • Endocrinology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Reproductive Health (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Radio Relay Systems (AREA)
  • Compression, Expansion, Code Conversion, And Decoders (AREA)
  • Peptides Or Proteins (AREA)
  • Cosmetics (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Compression Or Coding Systems Of Tv Signals (AREA)
  • Detergent Compositions (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Two-Way Televisions, Distribution Of Moving Picture Or The Like (AREA)
DE3850410T 1987-02-19 1988-02-09 cDNS KODIEREND FÜR SOMATOTROPIN, EXPRESSIONSVEKTOREN UND -WIRTE. Expired - Fee Related DE3850410T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1629487A 1987-02-19 1987-02-19
PCT/US1988/000328 WO1988006186A2 (en) 1987-02-19 1988-01-27 cDNAs ENCODING SOMATOTROPIN, EXPRESSION VECTORS AND HOSTS

Publications (2)

Publication Number Publication Date
DE3850410D1 true DE3850410D1 (de) 1994-07-28
DE3850410T2 DE3850410T2 (de) 1994-10-27

Family

ID=21776383

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3850410T Expired - Fee Related DE3850410T2 (de) 1987-02-19 1988-02-09 cDNS KODIEREND FÜR SOMATOTROPIN, EXPRESSIONSVEKTOREN UND -WIRTE.

Country Status (9)

Country Link
EP (1) EP0418219B1 (de)
JP (1) JP2580303B2 (de)
KR (1) KR960016704B1 (de)
AT (1) ATE107696T1 (de)
AU (1) AU615432B2 (de)
DE (1) DE3850410T2 (de)
DK (1) DK580188D0 (de)
HK (1) HK65497A (de)
WO (1) WO1988006186A2 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5104806A (en) * 1987-03-12 1992-04-14 Amgen, Inc. Porcine growth hormone analogs encoding dna
EP0398983A1 (de) * 1988-01-27 1990-11-28 The Upjohn Company Expressionsvektoren
US5268284A (en) * 1988-03-11 1993-12-07 The Upjohn Company Ribosome binding site
AU4315089A (en) * 1988-11-04 1990-05-28 Upjohn Company, The Somatotropin expression using a serratia promoter
ES2069277T3 (es) * 1990-01-31 1995-05-01 Upjohn Co Cepa ral-4, util para la produccion de proteinas y peptidos pequeños.

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ201918A (en) * 1981-09-18 1987-04-30 Genentech Inc N-terminal methionyl analogues of bovine growth hormone
EP0111814A3 (de) * 1982-12-16 1985-08-14 Mgi Pharma, Inc. Klonierung und Expression von nucleotiden Sequenzen die für Rinderwachstumshormon kodieren
GB8308236D0 (en) * 1983-03-25 1983-05-05 Celltech Ltd Dna vectors
JPS6011557A (ja) * 1983-04-19 1985-01-21 ジエネツクス・コ−ポレイシヨン クロ−ンヒツジ成長ホルモン遺伝子
BG49718A3 (en) * 1983-07-15 1992-01-15 Bio Technology General Corp Method for preparing of polypeptid with superoxiddismutasne activitty
US4710473A (en) * 1983-08-10 1987-12-01 Amgen, Inc. DNA plasmids
AU557486B2 (en) * 1984-01-27 1986-12-24 Monsanto Company Composition for improved bovine feeding and milk production
EP0159123B1 (de) * 1984-03-06 1992-01-15 Eli Lilly And Company Expressionsvektoren für Rinderwachstumshormonderivate
US4758512A (en) * 1984-03-06 1988-07-19 President And Fellows Of Harvard College Hosts and methods for producing recombinant products in high yields
EP0355460B1 (de) * 1988-08-24 2000-12-27 American Cyanamid Company Stabilisierung von Somatotropinen durch Modifikation von Cystein-Resten durch orts-spezifische Mutagenese oder chemische Derivatisierung

Also Published As

Publication number Publication date
WO1988006186A2 (en) 1988-08-25
WO1988006186A3 (en) 1988-11-03
AU615432B2 (en) 1991-10-03
HK65497A (en) 1997-05-23
AU1363988A (en) 1988-09-14
DK580188A (da) 1988-10-18
EP0418219A1 (de) 1991-03-27
EP0418219B1 (de) 1994-06-22
DK580188D0 (da) 1988-10-18
DE3850410T2 (de) 1994-10-27
KR960016704B1 (ko) 1996-12-20
JPH02502245A (ja) 1990-07-26
JP2580303B2 (ja) 1997-02-12
ATE107696T1 (de) 1994-07-15
KR890700663A (ko) 1989-04-26

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: PHARMACIA & UPJOHN CO., KALAMAZOO, MICH., US

8339 Ceased/non-payment of the annual fee