KR890009380A - 서방성 약학제제 - Google Patents
서방성 약학제제 Download PDFInfo
- Publication number
- KR890009380A KR890009380A KR1019880017054A KR880017054A KR890009380A KR 890009380 A KR890009380 A KR 890009380A KR 1019880017054 A KR1019880017054 A KR 1019880017054A KR 880017054 A KR880017054 A KR 880017054A KR 890009380 A KR890009380 A KR 890009380A
- Authority
- KR
- South Korea
- Prior art keywords
- pharmaceutical dosage
- dosage form
- form according
- active ingredient
- coating mixture
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
- A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
Abstract
내용 없음
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (9)
- 유효성분을 함유하며 에틸셀룰로오스와 유드라짓 RS의 혼합물로 피복된 미립자와 구성되는 것을 특징으로 하는 pH에 무관하게 유효성분의 조절된 용해를 허용하는 서방성 약학 투여형태.
- 제1항에 있어서, 피복혼합물은 60내지 40중량%의 에틸 셀룰로오스와 40내지 60중량%의 유드라짓 RS로 구성되는 것을 특징으로 하는 약학 투여형태.
- 제1항 또는 제2항에 있어서, 피복혼합물은 45중량%의 에틸 셀룰로오스와 55중량%의 유드라짓 RS로 구성되는 것을 특징으로 하는 약학 투여형태.
- 제1항 내지 제3항중 어느 하나에 있어서, 피복혼합물은 또한 가소제를 함유하는 것을 특징으로 하는 약학 투여형태.
- 제4항에 있어서, 피복 혼합물은 아세틸화 모노글리세리드를 함유하는 것을 특징으로 하는 약학 투여형태.
- 제1항 내지 제5항중 어느 하나에 있어서, 미립자는 희석제 및 결합제와 조합하여 유효성분을 함유하는 것을 특징으로 하는 약학 투여형태.
- 제6항에 있어서, 희석제를 미소 결정성 셀룰로오스인 것을 특징으로 하는 약학 투여형태.
- 제6항 또는 제7항에 있어서, 결합제는 카르복시 메틸셀룰로오스인 것을 특징으로 하는 약학 투여형태.
- 제1항 내지 제8항중 어느 한항에 있어서, 유효성분은 딜티아젬 염산염인 것을 특징으로 하는 약학 투여형태.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8717855 | 1987-12-21 | ||
FR8717855A FR2624732B1 (fr) | 1987-12-21 | 1987-12-21 | Formulation pharmaceutique a liberation prolongee |
Publications (2)
Publication Number | Publication Date |
---|---|
KR890009380A true KR890009380A (ko) | 1989-08-01 |
KR960009650B1 KR960009650B1 (en) | 1996-07-23 |
Family
ID=9358116
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR88017054A KR960009650B1 (en) | 1987-12-21 | 1988-12-20 | Sustained release pharmaceutical composition of diltiazem |
Country Status (23)
Country | Link |
---|---|
US (1) | US5112621A (ko) |
EP (1) | EP0322277B1 (ko) |
JP (1) | JPH082782B2 (ko) |
KR (1) | KR960009650B1 (ko) |
AR (1) | AR243378A1 (ko) |
AT (1) | ATE71837T1 (ko) |
AU (1) | AU609916B2 (ko) |
CA (1) | CA1332567C (ko) |
DE (1) | DE3868037D1 (ko) |
DK (1) | DK172370B1 (ko) |
ES (1) | ES2051881T3 (ko) |
FI (1) | FI97445C (ko) |
FR (1) | FR2624732B1 (ko) |
GR (1) | GR3003826T3 (ko) |
HU (1) | HU199685B (ko) |
IE (1) | IE60313B1 (ko) |
IL (1) | IL88736A (ko) |
IT (1) | IT8723196A0 (ko) |
MX (1) | MX169322B (ko) |
NO (1) | NO179357C (ko) |
NZ (1) | NZ227412A (ko) |
PT (1) | PT89276B (ko) |
ZA (1) | ZA889495B (ko) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100407519B1 (ko) * | 2001-08-31 | 2003-12-18 | 부광약품 주식회사 | 건조황산제일철과 방출조절제로서 엘-글루타민을 함유하는서방성 정제 및 그의 제조방법 |
Families Citing this family (53)
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JPH03145418A (ja) * | 1989-10-27 | 1991-06-20 | Sumitomo Pharmaceut Co Ltd | 塩基性薬物塩酸塩の徐放性製剤 |
DE69111287T2 (de) * | 1990-04-18 | 1995-12-21 | Asahi Chemical Ind | Kugelförmige Keimkerne, kugelförmige Granulate sowie Verfahren zu deren Herstellung. |
US5286497A (en) * | 1991-05-20 | 1994-02-15 | Carderm Capital L.P. | Diltiazem formulation |
ZA923474B (en) * | 1991-05-20 | 1993-01-27 | Marion Merrell Dow Inc | Diltiazem formulation |
US5288505A (en) * | 1991-06-26 | 1994-02-22 | Galephar P.R., Inc., Ltd. | Extended release form of diltiazem |
KR100221695B1 (ko) * | 1991-08-12 | 1999-09-15 | 그린 마틴, 브라이언 쥐 테슬리 | 약학적 구상 제형 |
GB2258613B (en) * | 1991-08-12 | 1996-01-10 | Euro Celtique Sa | Pharmaceutical diltiazem formulation |
US5968551A (en) * | 1991-12-24 | 1999-10-19 | Purdue Pharma L.P. | Orally administrable opioid formulations having extended duration of effect |
US5681585A (en) | 1991-12-24 | 1997-10-28 | Euro-Celtique, S.A. | Stabilized controlled release substrate having a coating derived from an aqueous dispersion of hydrophobic polymer |
US5472712A (en) * | 1991-12-24 | 1995-12-05 | Euroceltique, S.A. | Controlled-release formulations coated with aqueous dispersions of ethylcellulose |
US5580578A (en) * | 1992-01-27 | 1996-12-03 | Euro-Celtique, S.A. | Controlled release formulations coated with aqueous dispersions of acrylic polymers |
US7070806B2 (en) * | 1992-01-27 | 2006-07-04 | Purdue Pharma Lp | Controlled release formulations coated with aqueous dispersions of acrylic polymers |
US5260068A (en) * | 1992-05-04 | 1993-11-09 | Anda Sr Pharmaceuticals Inc. | Multiparticulate pulsatile drug delivery system |
US5837277A (en) * | 1992-06-04 | 1998-11-17 | Smithkline Beecham Corporation | Palatable pharmaceutical compositions |
WO1993024109A1 (en) * | 1992-06-04 | 1993-12-09 | Smithkline Beecham Corporation | Palatable pharmaceutical compositions |
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JP3264722B2 (ja) * | 1993-02-25 | 2002-03-11 | 第一製薬株式会社 | カプセル製剤 |
US5834024A (en) | 1995-01-05 | 1998-11-10 | Fh Faulding & Co. Limited | Controlled absorption diltiazem pharmaceutical formulation |
US5567441A (en) * | 1995-03-24 | 1996-10-22 | Andrx Pharmaceuticals Inc. | Diltiazem controlled release formulation |
FR2742660B1 (fr) | 1995-12-22 | 1998-04-03 | Ethypharm Lab Prod Ethiques | Nouvelles formes de microgranules a liberation prolongee contenant du diltiazem comme principe actif |
US6245351B1 (en) | 1996-03-07 | 2001-06-12 | Takeda Chemical Industries, Ltd. | Controlled-release composition |
US5830503A (en) * | 1996-06-21 | 1998-11-03 | Andrx Pharmaceuticals, Inc. | Enteric coated diltiazem once-a-day formulation |
AU8293498A (en) | 1997-07-02 | 1999-01-25 | Euro-Celtique S.A. | Stabilized sustained release tramadol formulations |
TR200002771T2 (tr) * | 1998-03-26 | 2001-02-21 | Fujisawa Pharmaceutical Co.,Ltd. | Devamlı salımı olan preparatlar |
US6524620B2 (en) | 1998-07-20 | 2003-02-25 | Andrx Pharmaceuticals, Inc. | Diltiazem controlled release formulation and method of manufacture |
US5997905A (en) * | 1998-09-04 | 1999-12-07 | Mcneil-Ppc | Preparation of pharmaceutically active particles |
UA67802C2 (uk) | 1998-10-23 | 2004-07-15 | Пфайзер Рісьоч Енд Дівелепмент Компані, Н.В./С.А. | Фармацевтична композиція з контрольованим вивільненням інгібітора цгмф фде-5 (варіанти), спосіб її одержання та спосіб лікування еректильної дисфункції |
GB9825988D0 (en) * | 1998-11-27 | 1999-01-20 | Pfizer Ltd | Indole derivatives |
US7108866B1 (en) | 1999-12-10 | 2006-09-19 | Biovall Laboratories International Srl | Chronotherapeutic diltiazem formulations and the administration thereof |
US20060153914A1 (en) * | 1999-12-10 | 2006-07-13 | Biovail Laboratories International S.R.L. | Chronotherapeutic diltiazem formulations and the administration thereof |
US6635277B2 (en) | 2000-04-12 | 2003-10-21 | Wockhardt Limited | Composition for pulsatile delivery of diltiazem and process of manufacture |
GB0018968D0 (en) * | 2000-08-02 | 2000-09-20 | Pfizer Ltd | Particulate composition |
US6663896B1 (en) | 2001-08-01 | 2003-12-16 | Alvin S. Blum | Delayed release aspirin for vascular obstruction prophylaxis |
KR100446818B1 (ko) * | 2001-11-06 | 2004-09-01 | 김재윤 | 질산 이소소르비드 서방성 펠렛 제형 |
RU2376988C2 (ru) | 2003-10-29 | 2009-12-27 | Уайт | Фармацевтические композиции замедленного высвобождения, содержащие аплиндор и его производные |
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KR100775957B1 (ko) * | 2006-02-07 | 2007-11-13 | 경상대학교산학협력단 | 애기장대 유래의 개화시기를 조절 단백질 co의 돌연변이단백질, 상기 단백질을 이용한 식물의 개화시기 조절전사인자의 분리방법 및 식물의 개화시기 조절방법 |
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WO2008135855A2 (en) * | 2007-05-03 | 2008-11-13 | Pfizer Products Inc. | Nanoparticles comprising a cholesteryl ester transfer protein inhibitor and a nonionizable polymer |
US9545384B2 (en) | 2007-06-04 | 2017-01-17 | Bend Research, Inc. | Nanoparticles comprising drug, a non-ionizable cellulosic polymer and tocopheryl polyethylene glocol succinate |
US8974827B2 (en) * | 2007-06-04 | 2015-03-10 | Bend Research, Inc. | Nanoparticles comprising a non-ionizable cellulosic polymer and an amphiphilic non-ionizable block copolymer |
US20100215747A1 (en) * | 2007-07-13 | 2010-08-26 | Corey Jay Bloom | Nanoparticles comprising ionizable, poorly water soluble cellulosic polymers |
US9233078B2 (en) * | 2007-12-06 | 2016-01-12 | Bend Research, Inc. | Nanoparticles comprising a non-ionizable polymer and an Amine-functionalized methacrylate copolymer |
WO2009073215A1 (en) * | 2007-12-06 | 2009-06-11 | Bend Research, Inc. | Pharmaceutical compositions comprising nanoparticles and a resuspending material |
EP2550863A1 (de) * | 2011-07-27 | 2013-01-30 | Bayer Intellectual Property GmbH | Aktivstoffhaltige Partikel auf Polyacrylat-Basis |
SI2970101T1 (sl) | 2013-03-14 | 2018-09-28 | Alkermes Pharma Ireland Limited | Prozdravila fumaratov in njihova uporaba pri zdravljenju različnih bolezni |
CA2936741C (en) | 2014-10-31 | 2018-11-06 | Purdue Pharma | Methods and compositions particularly for treatment of attention deficit disorder |
KR101639163B1 (ko) * | 2015-07-08 | 2016-07-22 | 울산대학교 산학협력단 | 저전송 영상 정보 및 센싱 정보 송수신 장치 및 이의 동작 방법 |
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Family Cites Families (7)
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HU187215B (en) * | 1983-01-26 | 1985-11-28 | Egyt Gyogyszervegyeszeti Gyar | Method for producing pharmaceutical product of high actor content and prolonged effect |
US4533674A (en) * | 1983-10-24 | 1985-08-06 | Basf Wyandotte Corporation | Process for preparing a sugar and starch free spray-dried vitamin C powder containing 90 percent ascorbic acid |
SE457505B (sv) * | 1984-01-10 | 1989-01-09 | Lejus Medical Ab | Laminatbelagd oral farmaceutisk komposition och foerfarande foer dess framstaellning |
JPH0625055B2 (ja) * | 1985-03-18 | 1994-04-06 | 日本ケミフア株式会社 | 持続性錠剤 |
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US4800087A (en) * | 1986-11-24 | 1989-01-24 | Mehta Atul M | Taste-masked pharmaceutical compositions |
-
1987
- 1987-12-21 FR FR8717855A patent/FR2624732B1/fr not_active Expired - Fee Related
- 1987-12-23 IT IT8723196A patent/IT8723196A0/it unknown
-
1988
- 1988-12-13 EP EP88403161A patent/EP0322277B1/fr not_active Expired - Lifetime
- 1988-12-13 DE DE8888403161T patent/DE3868037D1/de not_active Expired - Lifetime
- 1988-12-13 AT AT88403161T patent/ATE71837T1/de not_active IP Right Cessation
- 1988-12-13 ES ES88403161T patent/ES2051881T3/es not_active Expired - Lifetime
- 1988-12-20 IL IL88736A patent/IL88736A/xx unknown
- 1988-12-20 PT PT89276A patent/PT89276B/pt not_active IP Right Cessation
- 1988-12-20 NO NO885641A patent/NO179357C/no unknown
- 1988-12-20 IE IE381088A patent/IE60313B1/en not_active IP Right Cessation
- 1988-12-20 CA CA000586481A patent/CA1332567C/en not_active Expired - Lifetime
- 1988-12-20 JP JP63321856A patent/JPH082782B2/ja not_active Expired - Lifetime
- 1988-12-20 MX MX014267A patent/MX169322B/es unknown
- 1988-12-20 AR AR88312796A patent/AR243378A1/es active
- 1988-12-20 DK DK708088A patent/DK172370B1/da not_active IP Right Cessation
- 1988-12-20 HU HU886514A patent/HU199685B/hu unknown
- 1988-12-20 AU AU27077/88A patent/AU609916B2/en not_active Expired
- 1988-12-20 KR KR88017054A patent/KR960009650B1/ko not_active IP Right Cessation
- 1988-12-20 FI FI885884A patent/FI97445C/fi not_active IP Right Cessation
- 1988-12-20 ZA ZA889495A patent/ZA889495B/xx unknown
- 1988-12-20 NZ NZ227412A patent/NZ227412A/xx unknown
-
1990
- 1990-07-26 US US07/559,429 patent/US5112621A/en not_active Expired - Lifetime
-
1992
- 1992-02-18 GR GR920400248T patent/GR3003826T3/el unknown
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100407519B1 (ko) * | 2001-08-31 | 2003-12-18 | 부광약품 주식회사 | 건조황산제일철과 방출조절제로서 엘-글루타민을 함유하는서방성 정제 및 그의 제조방법 |
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FPAY | Annual fee payment |
Payment date: 20100719 Year of fee payment: 15 |
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