KR890007721A - 맛 은폐를 위한 수단을 포함하는 저작가능한 의약 정제 - Google Patents

맛 은폐를 위한 수단을 포함하는 저작가능한 의약 정제 Download PDF

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Publication number
KR890007721A
KR890007721A KR1019880014950A KR880014950A KR890007721A KR 890007721 A KR890007721 A KR 890007721A KR 1019880014950 A KR1019880014950 A KR 1019880014950A KR 880014950 A KR880014950 A KR 880014950A KR 890007721 A KR890007721 A KR 890007721A
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KR
South Korea
Prior art keywords
weight percent
chewable tablet
mixture
coated granules
cellulose acetate
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Application number
KR1019880014950A
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English (en)
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KR970007899B1 (ko
Inventor
니콜라스 줄리안 토마스
웨슬리 레이드보프 갈렌
Original Assignee
원본미기재
맥네일 컨슈머 프로덕츠 캄파니
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication of KR890007721A publication Critical patent/KR890007721A/ko
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Publication of KR970007899B1 publication Critical patent/KR970007899B1/ko

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

내용 없음

Description

맛 은폐를 위한 수단을 포함하는 저작가능한 의약 정제
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제1도는 본 발명에 따라 만들어진 저작가능한 APAP정제에 있어서 시간에 대한 백분율 용출의 그래프이다.
제2도는 본 발명에 따라 만들어진 저작가능한 APAP정제에 있어서 시간에 대한 백분율 용출의 그래프이다.

Claims (8)

  1. (a) 셀룰로스 아세테이트 또는 셀룰로스 아세테이트부티레이트 및 (b) 폴리비닐 피롤리돈의 혼합물로 피복된 의약을 각각 함유하는 압축 피복된 과립을 함유함을 특징으로하는 의약의저작가능한 정제.
  2. 제1항에 있어서, 의약이 아세틸 p-아미노페놀인 저작가능한 정제.
  3. 제1항에 있어서, 혼합물이 셀룰로오스 아세테이트 약 80내지 약 97중량%를 함유하며, 나머지가 폴리비닐 피롤리돈인 저작가능한 정제.
  4. 제2항에 있어서, 혼합물이 셀룰로오스 아세테이트 약 80내지 약 97중량%를 함유하며, 나머지가 폴리비닐 피롤리돈인 저작가능한 정제.
  5. 제1항에 있어서, 피복된 과립이 상술한 혼합물 약 5내지 약 20중량%를 함유하는 저작가능한 정제.
  6. 제2항에 있어서, 피복된 과립이 상술한 혼합물 약 5내지 약 20중량%를 함유하는 저작가능한 정제.
  7. 제3항에 있어서, 피복된 과립이 상술한 혼합물 약 5내지 약 20중량%를 함유하는 저작가능한 정제.
  8. 제4항에 있어서, 피복된 과립이 상술한 혼합물 약 5내지 약 20중량%를 함유하는 저작가능한 정제.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019880014950A 1987-11-16 1988-11-14 맛 은폐를 위한 수단을 포함하는 저작가능한 의약 정제 KR970007899B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12169287A 1987-11-16 1987-11-16
US121,692 1987-11-16

Publications (2)

Publication Number Publication Date
KR890007721A true KR890007721A (ko) 1989-07-05
KR970007899B1 KR970007899B1 (ko) 1997-05-17

Family

ID=22398221

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019880014950A KR970007899B1 (ko) 1987-11-16 1988-11-14 맛 은폐를 위한 수단을 포함하는 저작가능한 의약 정제

Country Status (14)

Country Link
EP (1) EP0317274B1 (ko)
JP (1) JP2599189B2 (ko)
KR (1) KR970007899B1 (ko)
AU (1) AU604170B2 (ko)
CA (1) CA1336069C (ko)
DE (1) DE3879111T2 (ko)
ES (1) ES2053768T3 (ko)
GR (1) GR1000261B (ko)
IE (1) IE62128B1 (ko)
MX (1) MX169815B (ko)
MY (1) MY103455A (ko)
NZ (1) NZ226822A (ko)
PH (1) PH25419A (ko)
PT (1) PT89006B (ko)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20020083324A (ko) * 2001-04-27 2002-11-02 조덕형 의약캡슐

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ234587A (en) * 1989-08-04 1991-11-26 Mcneil Ppc Inc A chewable pharmaceutical tablet of compressed coated granules
US5460825A (en) * 1990-05-23 1995-10-24 Mcneil-Ppc, Inc. Taste mask coatings for preparing chewable pharmaceutical tablets
US5075114A (en) * 1990-05-23 1991-12-24 Mcneil-Ppc, Inc. Taste masking and sustained release coatings for pharmaceuticals
KR920002148A (ko) * 1990-07-03 1992-02-28 안드레아 엘. 콜비 비스테로이드계 소염제에 의해 유발된 위장 증상을 완화시키기 위한 약제 조성물 및 이를 완화시키는 방법
US5260072A (en) * 1990-08-30 1993-11-09 Mcneil-Ppc, Inc. Rotogranulations and taste masking coatings for preparation of chewable pharmaceutical tablets
CA2052679C (en) * 1990-08-30 1997-12-02 Edward J. Roche Rotogranulations and taste masking coatings for preparation of chewable pharmaceutical tablets
CA2068402C (en) * 1991-06-14 1998-09-22 Michael R. Hoy Taste mask coatings for preparation of chewable pharmaceutical tablets
US5178867A (en) * 1991-08-19 1993-01-12 Alza Corporation Dosage form for delivering drug in short-time period
CA2128820A1 (en) * 1993-07-27 1995-01-28 Walter G. Gowan, Jr. Rapidly disintegrating pharmaceutical dosage form and process for preparation thereof
CA2128821A1 (en) * 1993-07-27 1995-01-28 Dilip J. Gole Freeze-dried pharmaceutical dosage form and process for separation thereof
US5536505A (en) * 1993-12-15 1996-07-16 Eastman Chemical Company Controlled release matrix system using cellulose acetate/poly-2-ethyl-2-oxazoline blends
US5523095A (en) * 1993-12-15 1996-06-04 Eastman Chemical Company Controlled release matrix system using cellulose acetate/polyvinylpyrrolidone blends
UA65607C2 (uk) * 1998-03-04 2004-04-15 Орто-Макнейл Фармацевтикал, Інк. Фармацевтична композиція (варіанти) та спосіб її приготування
CA2328100C (en) 1998-04-10 2011-01-18 Kyowa Hakko Kogyo Co. Ltd. Tablet production method and tablet
AU1240800A (en) * 1998-10-30 2000-05-22 Mcneil-Ppc, Inc. Granular, free-flowing pharmaceutical composition, and straw-like dosage form for oral administration thereof
US20030157247A1 (en) * 2000-06-14 2003-08-21 Yoshiro Chikami Method for producing coated bioactive granule
WO2009106824A2 (en) * 2008-02-25 2009-09-03 Cipla Limited Pharmaceutical formulations
WO2013164559A1 (en) * 2012-05-03 2013-11-07 Cipla Limited Antiretroviral composition

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE56151B1 (en) * 1983-10-20 1991-05-08 Elan Corp Plc Tablet formulation
IE58110B1 (en) * 1984-10-30 1993-07-14 Elan Corp Plc Controlled release powder and process for its preparation

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20020083324A (ko) * 2001-04-27 2002-11-02 조덕형 의약캡슐

Also Published As

Publication number Publication date
AU604170B2 (en) 1990-12-06
NZ226822A (en) 1990-03-27
CA1336069C (en) 1995-06-27
JP2599189B2 (ja) 1997-04-09
EP0317274B1 (en) 1993-03-10
KR970007899B1 (ko) 1997-05-17
PH25419A (en) 1991-07-01
IE883420L (en) 1989-05-16
JPH02106A (ja) 1990-01-05
AU2495488A (en) 1989-05-18
EP0317274A1 (en) 1989-05-24
PT89006A (pt) 1989-11-30
PT89006B (pt) 1993-09-30
ES2053768T3 (es) 1994-08-01
MY103455A (en) 1993-06-30
IE62128B1 (en) 1994-12-14
GR1000261B (el) 1992-05-12
DE3879111T2 (de) 1993-07-15
MX169815B (es) 1993-07-27
DE3879111D1 (de) 1993-04-15

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