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Tablets contg. 80-98% of a combination of a 2,4-diamino-pyrimidine and a sulphonamide, 1-5% of a granulating agent, and 1-5% of a dissolving agent with a swelling capability 5ml/g, used as a pharmaceutical formulation for oral administration, were prepd. Each tablet contained 400 mg sulfamethoxazole and 80mg trimethoprim. The tablets T50, or time required for 50% of the tablets to dissolve in 0.6% HCI, was 7 min.
KR7500268A1975-02-131975-02-13Process of manufacturing 2,4-diamino-pyrimidine with a sulphonamide
KR790000319B1
(en)
PROCESS FOR THE PREPARATION OF PHARMACEUTICAL OR MEDICINAL TABLETS FOR ORAL ADMINISTRATION, WITH DELAYED DELIVERY OF ACTIVE ACTIVE, IN TABLETS IN WHICH THE QUANTITY OF RELEASE OF THE ACTIVE AGENT IS DEFAULT.