KR890006221A - 발열물질의 제거방법 - Google Patents
발열물질의 제거방법 Download PDFInfo
- Publication number
- KR890006221A KR890006221A KR1019880013499A KR880013499A KR890006221A KR 890006221 A KR890006221 A KR 890006221A KR 1019880013499 A KR1019880013499 A KR 1019880013499A KR 880013499 A KR880013499 A KR 880013499A KR 890006221 A KR890006221 A KR 890006221A
- Authority
- KR
- South Korea
- Prior art keywords
- molecular weight
- exothermic material
- solution
- membrane
- exothermic
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
- B01D61/14—Ultrafiltration; Microfiltration
- B01D61/145—Ultrafiltration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/02—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
- A61L2/022—Filtration
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
-
- C—CHEMISTRY; METALLURGY
- C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F1/00—Treatment of water, waste water, or sewage
- C02F1/44—Treatment of water, waste water, or sewage by dialysis, osmosis or reverse osmosis
- C02F1/444—Treatment of water, waste water, or sewage by dialysis, osmosis or reverse osmosis by ultrafiltration or microfiltration
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Water Supply & Treatment (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Hydrology & Water Resources (AREA)
- Environmental & Geological Engineering (AREA)
- Organic Chemistry (AREA)
- Analytical Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Medicinal Preparation (AREA)
- Water Treatment By Sorption (AREA)
Abstract
내용 없음
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제1도 내지 제3도는 각각 본 발명의 방법의 바람직한 구체예의 개략도.
제4도 내지 제7도는 각각 본 발명의 장치의 실시예의 개략도.
제8도와 제9도는 2개의 UF막을 사용하는 본 발명의 장치의 실시예의 개략도.
Claims (4)
- (1)용액을 막으로 처리한 다음, (2)얻어진 용액을 발열물질 흡착제로 처리하는 단계로 구성되는 것을 특징으로 하는 발열물질을 함유하는 용액으로부터 발열물질을 함유하는 용액으로부터 발열물질을 제거하는 방법.
- 제1항에 있어서, (1)발열물질을 함유하는 용액을 임계분자량이 10,000 내지 200,000인 한외여과막으로 처리하고 수만 내지 수백만의 분자량을 갖는 발열물질을 제거하기 위하여 기공 크기를 크게하고 물에 침투속도를 크게한 다음에, (2)분자량 수만 또는 그 이하인 내독소와 분자량이 약 2,000인 지질 A를 제거하기 위하여 용액을 발열물질 흡착제로 처리하는 단계로 구성되는 것을 특징으로 하는 방법.
- 제1항 또는 제2항에 있어서, 상기 막이 평균 20A 내지 0.1 마이크로미터의 기공크기를 갖는 것을 특징으로 하는 방법.
- 제1항에 있어서, 그 용액이 발열물질과 약리학적인 유효성분을 포함하며, 그 막은 성분보다 큰 분자량을 갖는 내독소를 통과할 수 없으나 그 성분을 통과할 수 있는 기공크기를 갖는 것을 특징으로 하는 방법.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP62-261370 | 1987-10-16 | ||
JP26137087 | 1987-10-16 | ||
JP63-221877 | 1988-09-05 | ||
JP63221877A JPH0829316B2 (ja) | 1987-10-16 | 1988-09-05 | パイロジェンの除去方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
KR890006221A true KR890006221A (ko) | 1989-06-12 |
KR910004581B1 KR910004581B1 (ko) | 1991-07-06 |
Family
ID=26524551
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019880013499A KR910004581B1 (ko) | 1987-10-16 | 1988-10-15 | 발열물질의 제거방법 |
Country Status (7)
Country | Link |
---|---|
US (1) | US4909942A (ko) |
EP (1) | EP0312104B1 (ko) |
JP (1) | JPH0829316B2 (ko) |
KR (1) | KR910004581B1 (ko) |
CA (1) | CA1330049C (ko) |
DE (1) | DE3887812T2 (ko) |
ES (1) | ES2063013T3 (ko) |
Families Citing this family (37)
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US5589591A (en) * | 1986-07-03 | 1996-12-31 | Advanced Magnetics, Inc. | Endotoxin-free polysaccharides |
US5032281A (en) * | 1989-08-09 | 1991-07-16 | Daicel Chemical Industries, Ltd. | Separating membrane and separation method |
US5136032A (en) * | 1989-12-07 | 1992-08-04 | Daicel Chemical Industries, Ltd. | Method for separating phosphopolyol compounds using a separating agent |
US5104546A (en) * | 1990-07-03 | 1992-04-14 | Aluminum Company Of America | Pyrogens separations by ceramic ultrafiltration |
DE4029088C1 (ko) * | 1990-09-13 | 1992-02-13 | Fresenius Ag, 6380 Bad Homburg, De | |
US5242595A (en) * | 1991-04-25 | 1993-09-07 | U.S. Filter/Illinois Water Treatment, Inc. | Bacteria removal by ceramic microfiltration |
US5731164A (en) * | 1991-08-06 | 1998-03-24 | Sanorell Pharma Gmbh & Co. | method of checking the rate of removal of pyrogenic substances, in particular viruses, from organic material |
US5346889A (en) * | 1991-12-24 | 1994-09-13 | Wako Pure Chemical Industries, Ltd. | Process for extracting endotoxin |
AUPN030794A0 (en) | 1994-12-22 | 1995-01-27 | Aruba International Pty Ltd | Discontinuous plasma or serum delipidation |
IT1279209B1 (it) * | 1995-05-16 | 1997-12-04 | Bellco Spa | Filtro dializzatore/reattore atto ad effettuare la cattura di endotossine, e procedimento per la sua realizzazione. |
IT1275427B (it) * | 1995-05-16 | 1997-08-07 | Bracco Spa | Processo per la depirogenazione di soluzioni farmaceutiche iniettabili |
DE19609479A1 (de) * | 1996-03-11 | 1997-09-18 | Biotechnolog Forschung Gmbh | Endotoxin-spezifische Membranen |
DE19736472C1 (de) * | 1997-08-21 | 1999-04-22 | Bernhard Dr Sixt | Verfahren zum Herstellen von weitgehend nebenwirkungsfreien Kontrastmitteln |
EP1180241A4 (en) * | 1999-05-25 | 2003-03-05 | Univ Nebraska | METHOD FOR DETECTING AND QUANTIFYING ENDOTOXINS |
US6585890B2 (en) | 2000-02-04 | 2003-07-01 | Applied Research Associates, Inc. | Process for producing sterile water for injection from potable water |
US6716970B2 (en) * | 2000-04-21 | 2004-04-06 | Adjuvant Pharmaceuticals, Llc | Water soluble, randomly substituted partial N-partial O-acetylated chitosan, preserving compositions containing chitosan, and processes for making thereof |
DK1289629T3 (da) * | 2000-05-18 | 2004-11-22 | Novozymes As | Mikrofiltrering under anvendelse af aktivt kul |
US7439052B2 (en) * | 2000-06-29 | 2008-10-21 | Lipid Sciences | Method of making modified immunodeficiency virus particles |
US20090017069A1 (en) * | 2000-06-29 | 2009-01-15 | Lipid Sciences, Inc. | SARS Vaccine Compositions and Methods of Making and Using Them |
US7407662B2 (en) | 2000-06-29 | 2008-08-05 | Lipid Sciences, Inc. | Modified viral particles with immunogenic properties and reduced lipid content |
US7407663B2 (en) * | 2000-06-29 | 2008-08-05 | Lipid Sciences, Inc. | Modified immunodeficiency virus particles |
AUPQ846900A0 (en) * | 2000-06-29 | 2000-07-27 | Aruba International Pty Ltd | A vaccine |
US20060060520A1 (en) * | 2001-06-25 | 2006-03-23 | Bomberger David C | Systems and methods using a solvent for the removal of lipids from fluids |
AU2002322284A1 (en) | 2001-06-25 | 2003-01-08 | Lipid Sciences, Inc. | Systems and methods using multiple solvents for the removal of lipids from fluids |
US6991727B2 (en) | 2001-06-25 | 2006-01-31 | Lipid Sciences, Inc. | Hollow fiber contactor systems for removal of lipids from fluids |
US20030127386A1 (en) * | 2001-06-25 | 2003-07-10 | Bomberger David C. | Hollow fiber contactor systems for removal of lipids from fluids |
CA2451633C (en) * | 2001-06-25 | 2010-11-30 | Lipid Sciences, Inc. | Systems and methods using a solvent for the removal of lipids from fluids |
US7122149B2 (en) * | 2002-07-12 | 2006-10-17 | Applied Research Associates, Inc. | Apparatus and method for continuous depyrogenation and production of sterile water for injection |
EP1534243A4 (en) * | 2002-08-26 | 2008-08-13 | Lipid Sciences Inc | TREATMENT OF ALZHEIMER WITH ENTLIPIDED PROTEIN PARTICLES |
US7393826B2 (en) * | 2003-07-03 | 2008-07-01 | Lipid Sciences, Inc. | Methods and apparatus for creating particle derivatives of HDL with reduced lipid content |
JP2007527387A (ja) * | 2003-07-03 | 2007-09-27 | リピッド サイエンシーズ,インコーポレイテッド | 脂質含量の低下したhdlの粒子誘導体を製造するための方法及び装置 |
US7125967B2 (en) * | 2003-10-08 | 2006-10-24 | Adjuvant Pharmaceuticals, Llc | Water-soluble chitosan having low endotoxin concentration and methods for making and using the same |
US6960803B2 (en) * | 2003-10-23 | 2005-11-01 | Silicon Storage Technology, Inc. | Landing pad for use as a contact to a conductive spacer |
CN104190387B (zh) * | 2014-09-11 | 2016-08-17 | 福州新北生化工业有限公司 | 一种除液体中热原的凝胶及其制备方法和应用 |
CN105251049B (zh) * | 2015-09-29 | 2018-04-10 | 浙江星月生物科技股份有限公司 | 一种去除生物医用材料中细菌内毒素的离子缓冲液及应用 |
US11027052B2 (en) | 2017-11-22 | 2021-06-08 | HDL Therapuetics, Inc. | Systems and methods for priming fluid circuits of a plasma processing system |
JP2021509894A (ja) | 2017-12-28 | 2021-04-08 | エイチディーエル セラピューティクス インコーポレイテッドHdl Therapeutics, Inc. | ヒト血漿から抽出されたpre−β高密度リポタンパク質を保存および投与するための方法 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4261834A (en) * | 1978-05-18 | 1981-04-14 | Millipore Corporation | Device and process for removing pyrogens from aqueous solutions |
US4276177A (en) * | 1979-08-13 | 1981-06-30 | Vaponics Inc. | High efficiency filtration with impurity concentration and ultrafiltration rejection flow recirculation |
US4412985A (en) * | 1980-10-06 | 1983-11-01 | Edward Shanbrom | Depyrogenation process |
DE3173019D1 (en) * | 1980-12-02 | 1986-01-02 | Tracor | Preparation of infusion grade water |
GB2092470B (en) * | 1981-02-10 | 1984-07-18 | Tanabe Seiyaku Co | Method for reducing the pyrogen content of or removing pyrogens from solutions contaminated therewith |
AU540708B2 (en) * | 1982-01-25 | 1984-11-29 | Mitsubishi Rayon Company Limited | Water purifying method and system |
EP0110580A3 (en) * | 1982-11-03 | 1986-06-11 | Gelman Sciences, Inc. | Improved process for removing pyrogens utilizing a hydrophobic microporous membrane |
JPS59162991A (ja) * | 1983-03-07 | 1984-09-13 | Mitsubishi Rayon Co Ltd | 水処理システム |
JPS59196794A (ja) * | 1983-04-20 | 1984-11-08 | Toyo Soda Mfg Co Ltd | 脱エンド・トキシン方法 |
JPS6013215U (ja) * | 1983-07-04 | 1985-01-29 | 株式会社クラレ | 飲料水製造装置 |
US4610790A (en) * | 1984-02-10 | 1986-09-09 | Sterimatics Company Limited Partnership | Process and system for producing sterile water and sterile aqueous solutions |
JPS6118493A (ja) * | 1984-07-04 | 1986-01-27 | Hitachi Ltd | 純水製造装置における微生物汚染防止装置 |
-
1988
- 1988-09-05 JP JP63221877A patent/JPH0829316B2/ja not_active Expired - Lifetime
- 1988-10-12 US US07/256,729 patent/US4909942A/en not_active Expired - Fee Related
- 1988-10-14 CA CA000580150A patent/CA1330049C/en not_active Expired - Fee Related
- 1988-10-14 EP EP88117146A patent/EP0312104B1/en not_active Expired - Lifetime
- 1988-10-14 DE DE3887812T patent/DE3887812T2/de not_active Expired - Fee Related
- 1988-10-14 ES ES88117146T patent/ES2063013T3/es not_active Expired - Lifetime
- 1988-10-15 KR KR1019880013499A patent/KR910004581B1/ko not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DE3887812D1 (de) | 1994-03-24 |
JPH01194991A (ja) | 1989-08-04 |
EP0312104B1 (en) | 1994-02-16 |
CA1330049C (en) | 1994-06-07 |
ES2063013T3 (es) | 1995-01-01 |
US4909942A (en) | 1990-03-20 |
EP0312104A3 (en) | 1989-08-09 |
DE3887812T2 (de) | 1994-05-19 |
JPH0829316B2 (ja) | 1996-03-27 |
KR910004581B1 (ko) | 1991-07-06 |
EP0312104A2 (en) | 1989-04-19 |
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Payment date: 19960704 Year of fee payment: 6 |
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