KR890006221A - 발열물질의 제거방법 - Google Patents

발열물질의 제거방법 Download PDF

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Publication number
KR890006221A
KR890006221A KR1019880013499A KR880013499A KR890006221A KR 890006221 A KR890006221 A KR 890006221A KR 1019880013499 A KR1019880013499 A KR 1019880013499A KR 880013499 A KR880013499 A KR 880013499A KR 890006221 A KR890006221 A KR 890006221A
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South Korea
Prior art keywords
molecular weight
exothermic material
solution
membrane
exothermic
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KR1019880013499A
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English (en)
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KR910004581B1 (ko
Inventor
다다시 사또
다이조 와다나베
사도시 미노베
다까시 니시무라
마사히로 가고다니
도모노부 아세
젠지로 혼다
신지 나가마쓰
Original Assignee
아다찌 게이지로오
다나베 세이야꾸 가부시끼가이샤
고지마 아끼오
다이셀 가가꾸 고오교오 가부시끼가이샤
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Application filed by 아다찌 게이지로오, 다나베 세이야꾸 가부시끼가이샤, 고지마 아끼오, 다이셀 가가꾸 고오교오 가부시끼가이샤 filed Critical 아다찌 게이지로오
Publication of KR890006221A publication Critical patent/KR890006221A/ko
Application granted granted Critical
Publication of KR910004581B1 publication Critical patent/KR910004581B1/ko

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D61/00Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14Ultrafiltration; Microfiltration
    • B01D61/145Ultrafiltration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/02Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
    • A61L2/022Filtration
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • CCHEMISTRY; METALLURGY
    • C02TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02FTREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F1/00Treatment of water, waste water, or sewage
    • C02F1/44Treatment of water, waste water, or sewage by dialysis, osmosis or reverse osmosis
    • C02F1/444Treatment of water, waste water, or sewage by dialysis, osmosis or reverse osmosis by ultrafiltration or microfiltration

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Water Supply & Treatment (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Hydrology & Water Resources (AREA)
  • Environmental & Geological Engineering (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Medicinal Preparation (AREA)
  • Water Treatment By Sorption (AREA)

Abstract

내용 없음

Description

발열물질의 제거방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제1도 내지 제3도는 각각 본 발명의 방법의 바람직한 구체예의 개략도.
제4도 내지 제7도는 각각 본 발명의 장치의 실시예의 개략도.
제8도와 제9도는 2개의 UF막을 사용하는 본 발명의 장치의 실시예의 개략도.

Claims (4)

  1. (1)용액을 막으로 처리한 다음, (2)얻어진 용액을 발열물질 흡착제로 처리하는 단계로 구성되는 것을 특징으로 하는 발열물질을 함유하는 용액으로부터 발열물질을 함유하는 용액으로부터 발열물질을 제거하는 방법.
  2. 제1항에 있어서, (1)발열물질을 함유하는 용액을 임계분자량이 10,000 내지 200,000인 한외여과막으로 처리하고 수만 내지 수백만의 분자량을 갖는 발열물질을 제거하기 위하여 기공 크기를 크게하고 물에 침투속도를 크게한 다음에, (2)분자량 수만 또는 그 이하인 내독소와 분자량이 약 2,000인 지질 A를 제거하기 위하여 용액을 발열물질 흡착제로 처리하는 단계로 구성되는 것을 특징으로 하는 방법.
  3. 제1항 또는 제2항에 있어서, 상기 막이 평균 20A 내지 0.1 마이크로미터의 기공크기를 갖는 것을 특징으로 하는 방법.
  4. 제1항에 있어서, 그 용액이 발열물질과 약리학적인 유효성분을 포함하며, 그 막은 성분보다 큰 분자량을 갖는 내독소를 통과할 수 없으나 그 성분을 통과할 수 있는 기공크기를 갖는 것을 특징으로 하는 방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019880013499A 1987-10-16 1988-10-15 발열물질의 제거방법 KR910004581B1 (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP62-261370 1987-10-16
JP26137087 1987-10-16
JP63-221877 1988-09-05
JP63221877A JPH0829316B2 (ja) 1987-10-16 1988-09-05 パイロジェンの除去方法

Publications (2)

Publication Number Publication Date
KR890006221A true KR890006221A (ko) 1989-06-12
KR910004581B1 KR910004581B1 (ko) 1991-07-06

Family

ID=26524551

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019880013499A KR910004581B1 (ko) 1987-10-16 1988-10-15 발열물질의 제거방법

Country Status (7)

Country Link
US (1) US4909942A (ko)
EP (1) EP0312104B1 (ko)
JP (1) JPH0829316B2 (ko)
KR (1) KR910004581B1 (ko)
CA (1) CA1330049C (ko)
DE (1) DE3887812T2 (ko)
ES (1) ES2063013T3 (ko)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5589591A (en) * 1986-07-03 1996-12-31 Advanced Magnetics, Inc. Endotoxin-free polysaccharides
US5032281A (en) * 1989-08-09 1991-07-16 Daicel Chemical Industries, Ltd. Separating membrane and separation method
US5136032A (en) * 1989-12-07 1992-08-04 Daicel Chemical Industries, Ltd. Method for separating phosphopolyol compounds using a separating agent
US5104546A (en) * 1990-07-03 1992-04-14 Aluminum Company Of America Pyrogens separations by ceramic ultrafiltration
DE4029088C1 (ko) * 1990-09-13 1992-02-13 Fresenius Ag, 6380 Bad Homburg, De
US5242595A (en) * 1991-04-25 1993-09-07 U.S. Filter/Illinois Water Treatment, Inc. Bacteria removal by ceramic microfiltration
US5731164A (en) * 1991-08-06 1998-03-24 Sanorell Pharma Gmbh & Co. method of checking the rate of removal of pyrogenic substances, in particular viruses, from organic material
US5346889A (en) * 1991-12-24 1994-09-13 Wako Pure Chemical Industries, Ltd. Process for extracting endotoxin
AUPN030794A0 (en) 1994-12-22 1995-01-27 Aruba International Pty Ltd Discontinuous plasma or serum delipidation
IT1279209B1 (it) * 1995-05-16 1997-12-04 Bellco Spa Filtro dializzatore/reattore atto ad effettuare la cattura di endotossine, e procedimento per la sua realizzazione.
IT1275427B (it) * 1995-05-16 1997-08-07 Bracco Spa Processo per la depirogenazione di soluzioni farmaceutiche iniettabili
DE19609479A1 (de) * 1996-03-11 1997-09-18 Biotechnolog Forschung Gmbh Endotoxin-spezifische Membranen
DE19736472C1 (de) * 1997-08-21 1999-04-22 Bernhard Dr Sixt Verfahren zum Herstellen von weitgehend nebenwirkungsfreien Kontrastmitteln
EP1180241A4 (en) * 1999-05-25 2003-03-05 Univ Nebraska METHOD FOR DETECTING AND QUANTIFYING ENDOTOXINS
US6585890B2 (en) 2000-02-04 2003-07-01 Applied Research Associates, Inc. Process for producing sterile water for injection from potable water
US6716970B2 (en) * 2000-04-21 2004-04-06 Adjuvant Pharmaceuticals, Llc Water soluble, randomly substituted partial N-partial O-acetylated chitosan, preserving compositions containing chitosan, and processes for making thereof
DK1289629T3 (da) * 2000-05-18 2004-11-22 Novozymes As Mikrofiltrering under anvendelse af aktivt kul
US7439052B2 (en) * 2000-06-29 2008-10-21 Lipid Sciences Method of making modified immunodeficiency virus particles
US20090017069A1 (en) * 2000-06-29 2009-01-15 Lipid Sciences, Inc. SARS Vaccine Compositions and Methods of Making and Using Them
US7407662B2 (en) 2000-06-29 2008-08-05 Lipid Sciences, Inc. Modified viral particles with immunogenic properties and reduced lipid content
US7407663B2 (en) * 2000-06-29 2008-08-05 Lipid Sciences, Inc. Modified immunodeficiency virus particles
AUPQ846900A0 (en) * 2000-06-29 2000-07-27 Aruba International Pty Ltd A vaccine
US20060060520A1 (en) * 2001-06-25 2006-03-23 Bomberger David C Systems and methods using a solvent for the removal of lipids from fluids
AU2002322284A1 (en) 2001-06-25 2003-01-08 Lipid Sciences, Inc. Systems and methods using multiple solvents for the removal of lipids from fluids
US6991727B2 (en) 2001-06-25 2006-01-31 Lipid Sciences, Inc. Hollow fiber contactor systems for removal of lipids from fluids
US20030127386A1 (en) * 2001-06-25 2003-07-10 Bomberger David C. Hollow fiber contactor systems for removal of lipids from fluids
CA2451633C (en) * 2001-06-25 2010-11-30 Lipid Sciences, Inc. Systems and methods using a solvent for the removal of lipids from fluids
US7122149B2 (en) * 2002-07-12 2006-10-17 Applied Research Associates, Inc. Apparatus and method for continuous depyrogenation and production of sterile water for injection
EP1534243A4 (en) * 2002-08-26 2008-08-13 Lipid Sciences Inc TREATMENT OF ALZHEIMER WITH ENTLIPIDED PROTEIN PARTICLES
US7393826B2 (en) * 2003-07-03 2008-07-01 Lipid Sciences, Inc. Methods and apparatus for creating particle derivatives of HDL with reduced lipid content
JP2007527387A (ja) * 2003-07-03 2007-09-27 リピッド サイエンシーズ,インコーポレイテッド 脂質含量の低下したhdlの粒子誘導体を製造するための方法及び装置
US7125967B2 (en) * 2003-10-08 2006-10-24 Adjuvant Pharmaceuticals, Llc Water-soluble chitosan having low endotoxin concentration and methods for making and using the same
US6960803B2 (en) * 2003-10-23 2005-11-01 Silicon Storage Technology, Inc. Landing pad for use as a contact to a conductive spacer
CN104190387B (zh) * 2014-09-11 2016-08-17 福州新北生化工业有限公司 一种除液体中热原的凝胶及其制备方法和应用
CN105251049B (zh) * 2015-09-29 2018-04-10 浙江星月生物科技股份有限公司 一种去除生物医用材料中细菌内毒素的离子缓冲液及应用
US11027052B2 (en) 2017-11-22 2021-06-08 HDL Therapuetics, Inc. Systems and methods for priming fluid circuits of a plasma processing system
JP2021509894A (ja) 2017-12-28 2021-04-08 エイチディーエル セラピューティクス インコーポレイテッドHdl Therapeutics, Inc. ヒト血漿から抽出されたpre−β高密度リポタンパク質を保存および投与するための方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4261834A (en) * 1978-05-18 1981-04-14 Millipore Corporation Device and process for removing pyrogens from aqueous solutions
US4276177A (en) * 1979-08-13 1981-06-30 Vaponics Inc. High efficiency filtration with impurity concentration and ultrafiltration rejection flow recirculation
US4412985A (en) * 1980-10-06 1983-11-01 Edward Shanbrom Depyrogenation process
DE3173019D1 (en) * 1980-12-02 1986-01-02 Tracor Preparation of infusion grade water
GB2092470B (en) * 1981-02-10 1984-07-18 Tanabe Seiyaku Co Method for reducing the pyrogen content of or removing pyrogens from solutions contaminated therewith
AU540708B2 (en) * 1982-01-25 1984-11-29 Mitsubishi Rayon Company Limited Water purifying method and system
EP0110580A3 (en) * 1982-11-03 1986-06-11 Gelman Sciences, Inc. Improved process for removing pyrogens utilizing a hydrophobic microporous membrane
JPS59162991A (ja) * 1983-03-07 1984-09-13 Mitsubishi Rayon Co Ltd 水処理システム
JPS59196794A (ja) * 1983-04-20 1984-11-08 Toyo Soda Mfg Co Ltd 脱エンド・トキシン方法
JPS6013215U (ja) * 1983-07-04 1985-01-29 株式会社クラレ 飲料水製造装置
US4610790A (en) * 1984-02-10 1986-09-09 Sterimatics Company Limited Partnership Process and system for producing sterile water and sterile aqueous solutions
JPS6118493A (ja) * 1984-07-04 1986-01-27 Hitachi Ltd 純水製造装置における微生物汚染防止装置

Also Published As

Publication number Publication date
DE3887812D1 (de) 1994-03-24
JPH01194991A (ja) 1989-08-04
EP0312104B1 (en) 1994-02-16
CA1330049C (en) 1994-06-07
ES2063013T3 (es) 1995-01-01
US4909942A (en) 1990-03-20
EP0312104A3 (en) 1989-08-09
DE3887812T2 (de) 1994-05-19
JPH0829316B2 (ja) 1996-03-27
KR910004581B1 (ko) 1991-07-06
EP0312104A2 (en) 1989-04-19

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