KR890004166A - 생물학 응용 센서 - Google Patents

생물학 응용 센서 Download PDF

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Publication number
KR890004166A
KR890004166A KR1019880010671A KR880010671A KR890004166A KR 890004166 A KR890004166 A KR 890004166A KR 1019880010671 A KR1019880010671 A KR 1019880010671A KR 880010671 A KR880010671 A KR 880010671A KR 890004166 A KR890004166 A KR 890004166A
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South Korea
Prior art keywords
sensor
block
sensor according
layer
hemisphere
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KR1019880010671A
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English (en)
Inventor
프란시스 핀랜 마틴
모리스 미드글레이 존에드워드
알렉산더 챨스 스테픈
크리스토퍼 어램 제임스
Original Assignee
유스티스 앤터니 에번스
애머샴 인터내쇼날 피엘씨
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26292635&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR890004166(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB878719885A external-priority patent/GB8719885D0/en
Priority claimed from GB878720854A external-priority patent/GB8720854D0/en
Application filed by 유스티스 앤터니 에번스, 애머샴 인터내쇼날 피엘씨 filed Critical 유스티스 앤터니 에번스
Publication of KR890004166A publication Critical patent/KR890004166A/ko

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/534—Production of labelled immunochemicals with radioactive label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/55—Specular reflectivity
    • G01N21/552—Attenuated total reflection
    • G01N21/553—Attenuated total reflection and using surface plasmons
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings

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  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

내용 없음

Description

생물학 응용 센서
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제 1 및 제 2 도는 표면 플라스먼 공명 효과를 입증시키기 위한 실험장치의 개략도. 제 3 도는 본 발명의 일예에 따른 센서 단면의 개략도.

Claims (13)

  1. 전자계 방사선용 투명한 물질 블럭과, 상기 블럭으로 이루어진 최소한 제 1 표면의 일부분에 도표되어진 금속성 물질층과, 상기 금속성 층에 도표되어진 감지성 물질층과, 분석할 샘플과 반응하도록 감지층에 유도하기 위한 수단과, 상기 방사선원 상기 표면의 일부분으로 부터 벗어나 내부에서 반사되어 상기 투명한 블럭으로 지향된 전자계 반사선원과, 팬형태에 입사빔에서 상기 표면의 일부분에 상기 방사선원을 접속하기위한 수단과, 내부에서 반사된 빔을 수용하기 위해 위치 설정된 검출기 수단과, 상기 표면 내부로 입사한 팬-형태빔이 플라스먼공명을 일으키도록 입사각 열을 이루는 배열을 구비하는 생물학적, 생화학적 및 화학적 테스트용 센서에 있어서, 상기 감시수단에 의해 검출된 공명은 샘플 및 감지층 사이의 방응에 의한 것을 특징으로 하는 생물학적, 생화학적 또는 화학적 테스트용 센서.
  2. 제 1 항에 있어서, 상기 과원으로 부터나온 방사선은 제 2 곡선 표면을 지나 블럭에 입사되는 것을 특징으로 하는 센서.
  3. 제 2 항에 있어서, 상기 제 2 표먼의 곡률 중심부가 상기 제 1 표면에 배치된 것을 특징으로 하는 센서.
  4. 제 2 항 또는 제 3 항에 있어서, 상기 제 2 표면은 원형인 것을 특징으로 하는 센서.
  5. 제 2 항, 제 3 항 또는 제 4 항에 있어서, 전자계 방사선의 입력빔은 입사점에서 표면에 탄젠트가 되는 직각방향의 블럭에 입사되는 것을 특징으호 하는 센서.
  6. 전술한 항중 어느 한항에 있어서, 상기 검출기 수단은 상기 블럭의 외부에 위치 설정되고, 내부에서 반사된 빔은 블록의 제 3 곡선 표면을 지나 상기 블럭으로부터 나온것을 특징으로 하는 센서.
  7. 제 6 항에 있어서, 상기 제 3 표면의 곡률 중심부는 상기 제 1 표면에 배치된 것을 특징으로 하는 센서.
  8. 제 2 항 내지 제 7 항중 어느 한항에 있어서, 상기 투명체는 상기 제 1 표면인 반구의 평면과 상기 제 2 표면을 포함하는 반구의 원형 표면을 형성하고, 상기 제 1 표면의 일부분이 제 1 표면의 중심부에 위치 설정되는 것을 특징으로 하는 센서.
  9. 제 2 항 내지 제 7 항중 어느 한항에 있어서, 상기 투명체는 상기 제 1 표면인 반구의 평면과 상기 제 2 표면을 포함하는 반구의 곡선 표면을 형성하고 상기 제 1 표면의 일부분이 상기 제 1 표면의 길이방향 중심축상에 위치 설정되는 것을 특징으로 하는 센서.
  10. 제 8 항 또는 제 9 항에 있어서, 곡선 표면체의 정상부가 전달되어 절단형 반구 또는 반원인 것을 특징으로 하는 센서.
  11. 전술한 항중 어느 한항에 있어서, 검출기 수단은 방사빔 전체를 모으기 위해 위치 설정된 대영역 검출기 형태인 것을 특징으로 하는 센서.
  12. 전술한 항중 어느 한항에 있어서, 검출기 수단은 방사빔 전체를 모으기 위해 각이지게 일정하게 위치 설정된 검출기의 배열 형태를 이루는 것을 특징으로 하는 센서.
  13. 전술한 항중 어느 한항에 있어서, 상기 감지층은 항체층 형태 대응 항원을 포함하는 샘플과 방응하는 것을 특징으로 하는 센서.
    ※ 참고사항 : 최초출원내용에 의하여 공개하는 것임.
KR1019880010671A 1987-08-22 1988-08-22 생물학 응용 센서 KR890004166A (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB878719885A GB8719885D0 (en) 1987-08-22 1987-08-22 Sensor arrangement
GB8719885 1987-08-22
GB878720854A GB8720854D0 (en) 1987-09-04 1987-09-04 Biological sensors
GB8720854 1987-09-04

Publications (1)

Publication Number Publication Date
KR890004166A true KR890004166A (ko) 1989-04-20

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KR1019880010671A KR890004166A (ko) 1987-08-22 1988-08-22 생물학 응용 센서

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Country Link
US (1) US4997278A (ko)
EP (1) EP0305109B1 (ko)
JP (1) JP2758904B2 (ko)
KR (1) KR890004166A (ko)
AT (1) ATE92186T1 (ko)
AU (1) AU602423B2 (ko)
CA (1) CA1321488C (ko)
DE (1) DE3882620T2 (ko)
ES (1) ES2041802T3 (ko)
FI (1) FI94805C (ko)

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US4997278A (en) 1991-03-05
DE3882620T2 (de) 1993-11-04
CA1321488C (en) 1993-08-24
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FI94805B (fi) 1995-07-14
FI883868A (fi) 1989-02-23
AU2110988A (en) 1989-02-23
DE3882620D1 (de) 1993-09-02
EP0305109A1 (en) 1989-03-01
AU602423B2 (en) 1990-10-11
JPH01138443A (ja) 1989-05-31
EP0305109B1 (en) 1993-07-28
ATE92186T1 (de) 1994-02-25
ES2041802T3 (es) 1993-12-01
FI94805C (fi) 1995-10-25

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