KR880009909A - 2-아미노아세트아미드 유도체 - Google Patents
2-아미노아세트아미드 유도체 Download PDFInfo
- Publication number
- KR880009909A KR880009909A KR1019880001056A KR880001056A KR880009909A KR 880009909 A KR880009909 A KR 880009909A KR 1019880001056 A KR1019880001056 A KR 1019880001056A KR 880001056 A KR880001056 A KR 880001056A KR 880009909 A KR880009909 A KR 880009909A
- Authority
- KR
- South Korea
- Prior art keywords
- amino
- acetamide
- methylethyl
- diphenyl
- methyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
- C07C237/06—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Anesthesiology (AREA)
- General Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
내용 없음.
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (10)
- 일반식(Ⅰ)의 화합물.상기식에서, B는 수소, 저급 알킬(C1-C4) 또는 메톡시카보닐이고; R1은 수소 또는 메틸이며; W 및 Q는 독립적으로 페닐 및 4-플루오로페닐 중에서 선택된다.
- 2-아미노-N-(1,2-디페닐-1-메틸에틸)아세트아미드 히드로클로라이드.
- 2-아미노-N-〔1,2-비스(4-플루오로페닐)-1-메틸에틸〕아세트아미드.
- 2-아미노-N-(1-에틸-1,2-디페닐에틸)아세트아미드.
- 2-아미노-N-(1,2-디페닐에틸)아세트아미드 히드록클로라이드.
- 2-아미노-N-〔1,2-디페닐-1-(메톡시카보닐)에틸〕아세트아미드 말리에이트.
- (+)-2-아미노-N-(1,2-디페닐-1-메틸에틸)아세트아미드 푸마레이트.
- (-)-2-아미노-N-(1,2-디페닐-1-메틸에틸)아세트아미드 푸마레이트.
- 2-아미노-N-메틸-N-(1,2-디페닐에틸)아세트아미드 말리에이트.
- 2-아미노-N-메틸-N-(1,2-디페닐-1-메틸에틸)아세트아미드 말리에이트.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US011982 | 1987-02-02 | ||
US1198287A | 1987-02-06 | 1987-02-06 | |
US011,982 | 1987-02-06 |
Publications (2)
Publication Number | Publication Date |
---|---|
KR880009909A true KR880009909A (ko) | 1988-10-05 |
KR960004186B1 KR960004186B1 (ko) | 1996-03-27 |
Family
ID=21752812
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019880001056A KR960004186B1 (ko) | 1987-02-06 | 1988-02-05 | 2-아미노아세트아미드 유도체 및 이를 함유하는 약제학적 조성물 |
Country Status (19)
Country | Link |
---|---|
EP (1) | EP0279937B1 (ko) |
JP (1) | JPH0653715B2 (ko) |
KR (1) | KR960004186B1 (ko) |
AT (1) | ATE68174T1 (ko) |
AU (1) | AU601782B2 (ko) |
BR (1) | BR1100967A (ko) |
CA (1) | CA1338121C (ko) |
DE (1) | DE3773658D1 (ko) |
DK (1) | DK175076B1 (ko) |
ES (1) | ES2038159T3 (ko) |
FI (1) | FI91853C (ko) |
HK (1) | HK87793A (ko) |
IE (1) | IE59940B1 (ko) |
IL (1) | IL84305A (ko) |
MX (1) | MX9202994A (ko) |
NO (1) | NO174771C (ko) |
NZ (1) | NZ222359A (ko) |
PT (1) | PT86250B (ko) |
ZA (1) | ZA878799B (ko) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SG52662A1 (en) * | 1988-08-12 | 1998-09-28 | Astra Ab | Arylkalkyl-amines and -amides having anticonvulsant and neuroprotective properties |
AU639722B2 (en) * | 1989-10-27 | 1993-08-05 | Astra Aktiebolag | Use of arylalkylamides in the treatment of neurodegenerative diseases |
GB9626319D0 (en) * | 1996-12-19 | 1997-02-05 | Astra Pharma Prod | Synthetic method |
SE9702793D0 (sv) | 1997-07-24 | 1997-07-24 | Astra Pharma Prod | Novel formulation |
AR016212A1 (es) * | 1998-04-28 | 2001-06-20 | Astra Ab | Uso de compuestos farmaceuticos que tienen una actividad antagonista de nmda para preparar un medicamento para el tratamiento del sindrome de intestino irritable (ibs), y composiciones farmaceuticas |
SE9901077D0 (sv) * | 1999-03-23 | 1999-03-23 | Astra Ab | Novel use |
KR20040088519A (ko) | 2002-02-22 | 2004-10-16 | 뉴 리버 파마슈티칼스, 인크. | 활성 제제 전달 시스템 및 활성 제제의 보호 및 투여 방법 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE955508C (de) * | 1954-07-28 | 1957-01-03 | Cilag Ag | Verfahren zur Herstellung von antikonvulsivisch wirkenden Carbonsaeureamiden |
-
1987
- 1987-10-28 IL IL84305A patent/IL84305A/xx not_active IP Right Cessation
- 1987-10-29 NZ NZ222359A patent/NZ222359A/xx unknown
- 1987-10-30 IE IE293087A patent/IE59940B1/en not_active IP Right Cessation
- 1987-11-10 CA CA000551548A patent/CA1338121C/en not_active Expired - Fee Related
- 1987-11-20 AU AU81430/87A patent/AU601782B2/en not_active Ceased
- 1987-11-24 ZA ZA878799A patent/ZA878799B/xx unknown
- 1987-11-30 PT PT86250A patent/PT86250B/pt unknown
- 1987-12-14 DE DE87118506T patent/DE3773658D1/de not_active Expired - Fee Related
- 1987-12-14 EP EP87118506A patent/EP0279937B1/en not_active Expired - Lifetime
- 1987-12-14 AT AT87118506T patent/ATE68174T1/de not_active IP Right Cessation
- 1987-12-14 ES ES198787118506T patent/ES2038159T3/es not_active Expired - Lifetime
-
1988
- 1988-02-04 JP JP63022957A patent/JPH0653715B2/ja not_active Expired - Fee Related
- 1988-02-05 NO NO880523A patent/NO174771C/no unknown
- 1988-02-05 FI FI880548A patent/FI91853C/fi active IP Right Grant
- 1988-02-05 KR KR1019880001056A patent/KR960004186B1/ko not_active IP Right Cessation
- 1988-02-05 DK DK198800585A patent/DK175076B1/da not_active IP Right Cessation
-
1992
- 1992-06-18 MX MX9202994A patent/MX9202994A/es unknown
-
1993
- 1993-08-26 HK HK877/93A patent/HK87793A/xx not_active IP Right Cessation
-
1997
- 1997-05-14 BR BR1100967-5A patent/BR1100967A/pt active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
ZA878799B (en) | 1988-05-20 |
HK87793A (en) | 1993-09-03 |
DK58588D0 (da) | 1988-02-05 |
CA1338121C (en) | 1996-03-05 |
IE872930L (en) | 1988-08-06 |
IE59940B1 (en) | 1994-05-04 |
NO880523L (no) | 1988-08-08 |
ES2038159T3 (es) | 1993-07-16 |
EP0279937A1 (en) | 1988-08-31 |
IL84305A (en) | 1992-01-15 |
EP0279937B1 (en) | 1991-10-09 |
FI91853C (fi) | 1994-08-25 |
NO880523D0 (no) | 1988-02-05 |
MX9202994A (es) | 1992-07-01 |
FI880548A (fi) | 1988-08-07 |
DK58588A (da) | 1988-09-21 |
DE3773658D1 (ko) | 1991-11-14 |
FI91853B (fi) | 1994-05-13 |
NO174771C (no) | 1994-07-06 |
JPH0653715B2 (ja) | 1994-07-20 |
ATE68174T1 (de) | 1991-10-15 |
NO174771B (no) | 1994-03-28 |
AU601782B2 (en) | 1990-09-20 |
IL84305A0 (en) | 1988-03-31 |
NZ222359A (en) | 1989-12-21 |
KR960004186B1 (ko) | 1996-03-27 |
PT86250B (pt) | 1991-02-08 |
PT86250A (en) | 1987-12-01 |
FI880548A0 (fi) | 1988-02-05 |
DK175076B1 (da) | 2004-05-24 |
JPS63216853A (ja) | 1988-09-09 |
BR1100967A (pt) | 1999-10-13 |
AU8143087A (en) | 1988-08-04 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
A201 | Request for examination | ||
E902 | Notification of reason for refusal | ||
G160 | Decision to publish patent application | ||
N231 | Notification of change of applicant | ||
E701 | Decision to grant or registration of patent right | ||
GRNT | Written decision to grant | ||
FPAY | Annual fee payment |
Payment date: 20060113 Year of fee payment: 11 |
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LAPS | Lapse due to unpaid annual fee |