KR880000970B1 - 생물학적 유용성이 높은 경구용 약학적 조성물의 제조방법 - Google Patents

생물학적 유용성이 높은 경구용 약학적 조성물의 제조방법 Download PDF

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Publication number
KR880000970B1
KR880000970B1 KR8203134A KR820003134A KR880000970B1 KR 880000970 B1 KR880000970 B1 KR 880000970B1 KR 8203134 A KR8203134 A KR 8203134A KR 820003134 A KR820003134 A KR 820003134A KR 880000970 B1 KR880000970 B1 KR 880000970B1
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KR
South Korea
Prior art keywords
water
drug
oil
unsaturated fatty
fatty acid
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Expired
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KR8203134A
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English (en)
Korean (ko)
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KR840000233A (ko
Inventor
시메수 모또야마
사또시 사또
세이이찌 우메다
히로쓰네 야수미
에미꼬 수도
다꾸이찌 쯔지노
아끼라 아까자와
Original Assignee
후꾸시마 야스유기
후로인트 산교 가부시끼 가이샤
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP10977781A external-priority patent/JPS5813508A/ja
Priority claimed from JP17516881A external-priority patent/JPS5877810A/ja
Application filed by 후꾸시마 야스유기, 후로인트 산교 가부시끼 가이샤 filed Critical 후꾸시마 야스유기
Publication of KR840000233A publication Critical patent/KR840000233A/ko
Application granted granted Critical
Publication of KR880000970B1 publication Critical patent/KR880000970B1/ko
Expired legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Emergency Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR8203134A 1981-07-14 1982-07-14 생물학적 유용성이 높은 경구용 약학적 조성물의 제조방법 Expired KR880000970B1 (ko)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
JP10977781A JPS5813508A (ja) 1981-07-14 1981-07-14 ポリグリセロール飽和脂肪酸エステルを含む経口薬剤組成物
JP109777/81 1981-07-14
JP109777/81? 1981-07-14
JP175168/81 1981-11-01
JP17516881A JPS5877810A (ja) 1981-11-01 1981-11-01 ポリグリセロ−ル不飽和脂肪酸エステルを含む経口薬剤組成物
JP175168/81? 1981-11-11

Publications (2)

Publication Number Publication Date
KR840000233A KR840000233A (ko) 1984-02-18
KR880000970B1 true KR880000970B1 (ko) 1988-06-07

Family

ID=26449492

Family Applications (1)

Application Number Title Priority Date Filing Date
KR8203134A Expired KR880000970B1 (ko) 1981-07-14 1982-07-14 생물학적 유용성이 높은 경구용 약학적 조성물의 제조방법

Country Status (4)

Country Link
US (1) US4751241A (OSRAM)
KR (1) KR880000970B1 (OSRAM)
CH (1) CH652307A5 (OSRAM)
DE (1) DE3224619A1 (OSRAM)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5656620A (en) * 1984-01-28 1997-08-12 Ismail; Roshdy Method for treating pain
DE3588023D1 (de) * 1984-01-28 1995-06-29 Roshdy Ismail Mittel zur Behandlung von Herzerkrankungen.
US5229164A (en) * 1985-12-19 1993-07-20 Capsoid Pharma Gmbh Process for producing individually dosed administration forms
SE457693B (sv) * 1986-07-01 1989-01-23 Drilletten Ab Komposition med reglerad frigoering vari ett biologiskt material aer loest eller dispergerat i en l2-fas
JP2643217B2 (ja) * 1988-01-22 1997-08-20 エーザイ株式会社 脂溶性物質水性液
AU645003B2 (en) * 1988-11-08 1994-01-06 Takeda Chemical Industries Ltd. Sustained release preparations
JP2893191B2 (ja) * 1988-11-08 1999-05-17 武田薬品工業株式会社 放出制御性マトリックス剤
JPH02188523A (ja) * 1989-01-13 1990-07-24 M S C:Kk 睡眠時無呼吸症治療薬
DE69008534T2 (de) * 1989-08-03 1994-08-18 Hisamitsu Pharmaceutical Co Hautcremezubereitung zur äusserlichen verwendung.
IE65045B1 (en) * 1990-04-28 1995-10-04 Takeda Chemical Industries Ltd Granulated preparations and method of producing the same
US5179122A (en) * 1991-02-11 1993-01-12 Eastman Kodak Company Nutritional supplement containing vitamin e
EP0573978B1 (en) * 1992-06-12 1999-04-21 Kao Corporation Bath additive composition comprising surfactant-containing seamless capsules and method for producing the capsules.
IT1256386B (it) * 1992-11-13 1995-12-04 Luigi Boltri Composizioni farmaceutiche comprendenti un farmaco,una sostanza polimerica reticolata,un olio ed un agente tensioattivo
WO1994015595A1 (en) * 1993-01-06 1994-07-21 Jemo-Pharm A/S Medium comprising a pharmacological/biological active substance
DE19647352C2 (de) * 1996-11-15 2000-06-29 Aqua Nova Getraenketechnologie Nicht alkoholisches Getränk mit einem Gehalt an Q 10
DE19722405A1 (de) * 1997-05-28 1998-12-03 Ifac Inst Fuer Angewandte Coll Einkapseln von wasserunlöslichen Wirkstoffen mit amphiphilem Charakter
WO1999022719A1 (fr) * 1997-10-30 1999-05-14 Morishita Jintan Co., Ltd. Preparation de capsule contenant un acide gras insature ou un derive de celui-ci, et procede de fabrication
US6280770B1 (en) 1998-08-13 2001-08-28 Cima Labs Inc. Microemulsions as solid dosage forms for oral administration
IT1304406B1 (it) * 1998-10-21 2001-03-19 Danital Italia S R L Preparazione per la veicolazione di principi attivi basata su acidigrassi polinsaturi del gruppo omega 3.
CZ20022047A3 (cs) 1999-12-23 2003-09-17 Pfizer Products Inc. Farmaceutické kompozice poskytující zvýšenou koncentraci léčiva
US6692771B2 (en) * 2001-02-23 2004-02-17 Cima Labs Inc. Emulsions as solid dosage forms for oral administration
DE10133305B4 (de) * 2001-07-12 2004-06-03 Aquanova German Solubilisate Technologies (Agt) Gmbh Ubichinon Konzentrat
JP3549197B2 (ja) * 2001-08-10 2004-08-04 日清ファルマ株式会社 ユビキノン含有製剤
TW200302056A (en) * 2002-01-18 2003-08-01 Kaneka Corp Method for stabilizing reduced coenzyme Q10 and composition therefor
CA2513276C (en) * 2003-01-17 2012-09-04 Taiyo Kagaku Co., Ltd. Compositions containing coenzyme q10
CA2520660C (en) * 2003-03-28 2013-08-20 Sigmoid Biotechnologies Limited Solid oral dosage form containing seamless microcapsules
US20080020018A1 (en) * 2004-09-27 2008-01-24 Joey Moodley Combination Products
US8480797B2 (en) 2005-09-12 2013-07-09 Abela Pharmaceuticals, Inc. Activated carbon systems for facilitating use of dimethyl sulfoxide (DMSO) by removal of same, related compounds, or associated odors
AU2006291134C1 (en) 2005-09-12 2013-08-15 Abela Pharmaceuticals, Inc. Systems for removing dimethyl sulfoxide (DMSO) or related compounds, or odors associated with same
WO2007033180A1 (en) 2005-09-12 2007-03-22 Abela Pharmaceuticals, Inc. Materials for facilitating administration of dimethyl sulfoxide (dmso) and related compounds
EP1937286B1 (en) 2005-09-12 2016-03-09 Abela Pharmaceuticals, Inc. Compositions comprising dimethyl sulfoxide (dmso)
US8506956B2 (en) * 2005-10-31 2013-08-13 Kaneka Corporation Method for stabilizing reduced coenzyme Q10
JP5128801B2 (ja) * 2006-10-16 2013-01-23 フロイント産業株式会社 高水分散性粉末とその製造方法
WO2008122965A2 (en) * 2007-04-04 2008-10-16 Sigmoid Pharma Limited Pharmaceutical cyclosporin compositions
JP2010527285A (ja) * 2007-04-26 2010-08-12 シグモイド・ファーマ・リミテッド 複数のミニカプセルの製造
WO2008132710A2 (en) * 2007-05-01 2008-11-06 Sigmoid Pharma Limited Pharmaceutical nimodipine compositions
TW200918096A (en) * 2007-06-22 2009-05-01 Kaneka Corp Composition comprising bioactive substance
EP2186789B1 (en) * 2007-08-22 2013-12-25 Kaneka Corporation Method of producing reduced coenzyme q10 and method of stabilizing the same
WO2009025372A1 (ja) * 2007-08-23 2009-02-26 Kaneka Corporation 還元型補酵素ｑ１０含有組成物及びその安定化方法
BRPI0921494A2 (pt) * 2008-11-03 2018-10-30 Prad Reasearch And Development Ltd método de planejamento de uma operação de amostragem para uma formação subterrãnea, método de contolar uma operação de amostragem de formação subterrânea, método de controlar uma operação de perfuração para uma formação subterrãnea, e método de realizar uma amostragem durante a operação de perfuração.
WO2010133609A2 (en) 2009-05-18 2010-11-25 Sigmoid Pharma Limited Composition comprising oil drops
US9878036B2 (en) 2009-08-12 2018-01-30 Sigmoid Pharma Limited Immunomodulatory compositions comprising a polymer matrix and an oil phase
US9855212B2 (en) 2009-10-30 2018-01-02 Abela Pharmaceuticals, Inc. Dimethyl sulfoxide (DMSO) or DMSO and methylsulfonylmethane (MSM) formulations to treat infectious diseases
GB201020032D0 (en) 2010-11-25 2011-01-12 Sigmoid Pharma Ltd Composition
GB201212010D0 (en) 2012-07-05 2012-08-22 Sigmoid Pharma Ltd Formulations
GB201319791D0 (en) 2013-11-08 2013-12-25 Sigmoid Pharma Ltd Formulations
AU2015217651A1 (en) * 2014-02-13 2016-09-01 Clariant International Ltd. Preparation of polyglycerols
AU2015341695B2 (en) 2014-11-07 2021-07-08 Sublimity Therapeutics Limited Compositions comprising cyclosporin
JP7560982B2 (ja) * 2020-09-18 2024-10-03 日清ファルマ株式会社 コエンザイムｑ１０含有水溶性組成物

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3932634A (en) * 1973-06-28 1976-01-13 Pfizer Inc. High potency vitamin water dispersible formulations
US3966632A (en) * 1974-06-06 1976-06-29 G. D. Searle & Co. Vegetable oil emulsion
US4073943A (en) * 1974-09-11 1978-02-14 Apoteksvarucentralen Vitrum Ab Method of enhancing the administration of pharmalogically active agents
US3996355A (en) * 1975-01-02 1976-12-07 American Home Products Corporation Permanent suspension pharmaceutical dosage form
SE445174B (sv) * 1978-03-07 1986-06-09 Sandoz Ag Farmaceutisk komposition innehallande en cyklosporin och en berarsubstans
JPS574916A (en) * 1980-05-28 1982-01-11 Furointo Sangyo Kk Activation of medical preparation
US4327076A (en) * 1980-11-17 1982-04-27 Life Savers, Inc. Compressed chewable antacid tablet and method for forming same
US4327077A (en) * 1981-05-29 1982-04-27 Life Savers, Inc. Compressed chewable antacid tablet and method for forming same

Also Published As

Publication number Publication date
DE3224619A1 (de) 1983-05-19
KR840000233A (ko) 1984-02-18
CH652307A5 (de) 1985-11-15
US4751241A (en) 1988-06-14
DE3224619C2 (OSRAM) 1990-10-04

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