JPS574916A - Activation of medical preparation - Google Patents
Activation of medical preparationInfo
- Publication number
- JPS574916A JPS574916A JP7010480A JP7010480A JPS574916A JP S574916 A JPS574916 A JP S574916A JP 7010480 A JP7010480 A JP 7010480A JP 7010480 A JP7010480 A JP 7010480A JP S574916 A JPS574916 A JP S574916A
- Authority
- JP
- Japan
- Prior art keywords
- water
- preparation
- ubidecarenone
- emulsified
- fine particles
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Medicinal Preparation (AREA)
Abstract
PURPOSE: A medicine such as ubidecarenone is emulsified by a specific method, then water is removed to produce the objective preparation of high intestinal absorption.
CONSTITUTION: A medicine bearing isoprenoid side chains such as ubidecarenone, menatetrenone or tocopherol nicotinate is dissolved in a hydrophobic organic solvent such as jujube oil. The solution is emulsified in water in the presence of a water- soluble high-molecular substance such as gum arabic and at least the water is evaporated off to give the preparation of fine particles. The resultant preparation is readily redispersible in water due to its fine particles and shows high intestinal absorption, thus being high bioavailability.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP7010480A JPS574916A (en) | 1980-05-28 | 1980-05-28 | Activation of medical preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP7010480A JPS574916A (en) | 1980-05-28 | 1980-05-28 | Activation of medical preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS574916A true JPS574916A (en) | 1982-01-11 |
Family
ID=13421887
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP7010480A Pending JPS574916A (en) | 1980-05-28 | 1980-05-28 | Activation of medical preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS574916A (en) |
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS62294612A (en) * | 1986-06-16 | 1987-12-22 | Eisai Co Ltd | Menatetrenone-containing composition having improved absorption |
US4751241A (en) * | 1981-07-14 | 1988-06-14 | Freund Industrial Company, Ltd. | Pharmaceutical composition of cyclandelate having a high degree of bioavailability |
JPH10502621A (en) * | 1994-07-01 | 1998-03-10 | エフ・ホフマン−ラ ロシユ アーゲー | Multiple microencapsulation of lipophilic substances |
US7026361B2 (en) | 2001-08-10 | 2006-04-11 | Nisshin Pharma Inc. | Composition comprising ubiquinone |
WO2007148798A1 (en) * | 2006-06-22 | 2007-12-27 | Kaneka Corporation | Reduced coenzyme q10-containing composition and method for producing the same |
JPWO2009001786A1 (en) * | 2007-06-22 | 2010-08-26 | 株式会社カネカ | Bioactive substance-containing composition |
JP5256041B2 (en) * | 2006-10-31 | 2013-08-07 | 株式会社カネカ | Biologically active substance-containing particulate composition and method for producing the same |
-
1980
- 1980-05-28 JP JP7010480A patent/JPS574916A/en active Pending
Cited By (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4751241A (en) * | 1981-07-14 | 1988-06-14 | Freund Industrial Company, Ltd. | Pharmaceutical composition of cyclandelate having a high degree of bioavailability |
JPS62294612A (en) * | 1986-06-16 | 1987-12-22 | Eisai Co Ltd | Menatetrenone-containing composition having improved absorption |
JPH10502621A (en) * | 1994-07-01 | 1998-03-10 | エフ・ホフマン−ラ ロシユ アーゲー | Multiple microencapsulation of lipophilic substances |
US7026361B2 (en) | 2001-08-10 | 2006-04-11 | Nisshin Pharma Inc. | Composition comprising ubiquinone |
WO2007148798A1 (en) * | 2006-06-22 | 2007-12-27 | Kaneka Corporation | Reduced coenzyme q10-containing composition and method for producing the same |
US9295656B2 (en) | 2006-06-22 | 2016-03-29 | Kaneka Corporation | Composition containing reduced coenzyme Q10 and production method thereof |
US9981899B2 (en) | 2006-06-22 | 2018-05-29 | Kaneka Corporation | Composition containing reduced coenzyme Q10 and production method thereof |
JP5256041B2 (en) * | 2006-10-31 | 2013-08-07 | 株式会社カネカ | Biologically active substance-containing particulate composition and method for producing the same |
JPWO2009001786A1 (en) * | 2007-06-22 | 2010-08-26 | 株式会社カネカ | Bioactive substance-containing composition |
JP5343002B2 (en) * | 2007-06-22 | 2013-11-13 | 株式会社カネカ | Bioactive substance-containing composition |
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