KR870010080A - 면역촉진 활성을 갖는 트리펩티드 - Google Patents
면역촉진 활성을 갖는 트리펩티드 Download PDFInfo
- Publication number
- KR870010080A KR870010080A KR870003455A KR870003455A KR870010080A KR 870010080 A KR870010080 A KR 870010080A KR 870003455 A KR870003455 A KR 870003455A KR 870003455 A KR870003455 A KR 870003455A KR 870010080 A KR870010080 A KR 870010080A
- Authority
- KR
- South Korea
- Prior art keywords
- tripeptide
- immunostimulatory activity
- arg
- ala
- trifluoroacetate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 230000003308 immunostimulating effect Effects 0.000 title claims 3
- QNAYBMKLOCPYGJ-REOHCLBHSA-N L-alanine Chemical compound C[C@H](N)C(O)=O QNAYBMKLOCPYGJ-REOHCLBHSA-N 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 claims 1
- SGYSTDWPNPKJPP-GUBZILKMSA-N Arg-Ala-Arg Chemical compound NC(=N)NCCC[C@H](N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O SGYSTDWPNPKJPP-GUBZILKMSA-N 0.000 claims 1
- 239000004475 Arginine Substances 0.000 claims 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims 1
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 claims 1
- DTQVDTLACAAQTR-UHFFFAOYSA-M Trifluoroacetate Chemical compound [O-]C(=O)C(F)(F)F DTQVDTLACAAQTR-UHFFFAOYSA-M 0.000 claims 1
- 235000004279 alanine Nutrition 0.000 claims 1
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 claims 1
- 230000007812 deficiency Effects 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 210000000987 immune system Anatomy 0.000 claims 1
- 238000007911 parenteral administration Methods 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 230000001225 therapeutic effect Effects 0.000 claims 1
- 238000010586 diagram Methods 0.000 description 1
- 238000004128 high performance liquid chromatography Methods 0.000 description 1
- 230000003595 spectral effect Effects 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0815—Tripeptides with the first amino acid being basic
- C07K5/0817—Tripeptides with the first amino acid being basic the first amino acid being Arg
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT20027/86A IT1188646B (it) | 1986-04-09 | 1986-04-09 | Tripeptide ad attivita' immunostimolante |
| IT20027A | 1986-04-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR870010080A true KR870010080A (ko) | 1987-11-30 |
Family
ID=11163225
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR870003455A Ceased KR870010080A (ko) | 1986-04-09 | 1987-04-09 | 면역촉진 활성을 갖는 트리펩티드 |
Country Status (17)
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2058553C1 (ru) * | 1994-03-18 | 1996-04-20 | Иван Николаевич Головистиков | Способ определения супрессорного звена иммунного статуса человека |
| RU2056852C1 (ru) * | 1994-03-18 | 1996-03-27 | Иван Николаевич Головистиков | Средство для лечения аутоиммунных заболеваний с иммунодефицитом супрессоров и способ лечения аутоиммунных заболеваний |
| GB0130285D0 (en) * | 2001-12-19 | 2002-02-06 | Astrazeneca Ab | Chemical process |
| GB0130286D0 (en) * | 2001-12-19 | 2002-02-06 | Astrazeneca Ab | Chemical process |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3778426A (en) * | 1970-12-16 | 1973-12-11 | Research Corp | Therapeutically useful polypeptides |
| US4215112A (en) * | 1979-03-14 | 1980-07-29 | Ortho Pharmaceutical Corporation | Tripeptides and methods |
-
1986
- 1986-04-09 IT IT20027/86A patent/IT1188646B/it active
-
1987
- 1987-04-06 IE IE88187A patent/IE59806B1/en not_active IP Right Cessation
- 1987-04-07 CH CH1336/87A patent/CH676467A5/it not_active IP Right Cessation
- 1987-04-07 SE SE8701457A patent/SE8701457L/ not_active Application Discontinuation
- 1987-04-08 CA CA000534201A patent/CA1322715C/en not_active Expired - Fee Related
- 1987-04-08 NL NL8700827A patent/NL8700827A/nl not_active Application Discontinuation
- 1987-04-08 AU AU71182/87A patent/AU597048B2/en not_active Ceased
- 1987-04-09 GR GR870568A patent/GR870568B/el unknown
- 1987-04-09 FR FR878705021A patent/FR2597107B1/fr not_active Expired - Fee Related
- 1987-04-09 JP JP62087896A patent/JPH0645637B2/ja not_active Expired - Lifetime
- 1987-04-09 AR AR87307260A patent/AR242799A1/es active
- 1987-04-09 GB GB8708492A patent/GB2189491B/en not_active Expired - Fee Related
- 1987-04-09 AT AT0088387A patent/ATA88387A/de not_active Application Discontinuation
- 1987-04-09 ES ES8701042A patent/ES2003043A6/es not_active Expired
- 1987-04-09 KR KR870003455A patent/KR870010080A/ko not_active Ceased
- 1987-04-09 BE BE8700377A patent/BE1000263A4/fr not_active IP Right Cessation
- 1987-04-09 DE DE19873712050 patent/DE3712050A1/de active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0645637B2 (ja) | 1994-06-15 |
| FR2597107A1 (fr) | 1987-10-16 |
| GB2189491B (en) | 1990-02-21 |
| IE870881L (en) | 1987-10-09 |
| GB2189491A (en) | 1987-10-28 |
| FR2597107B1 (fr) | 1991-02-22 |
| IT8620027A1 (it) | 1987-10-09 |
| AR242799A1 (es) | 1993-05-31 |
| IT8620027A0 (it) | 1986-04-09 |
| DE3712050C2 (enrdf_load_stackoverflow) | 1992-02-13 |
| DE3712050A1 (de) | 1987-10-15 |
| NL8700827A (nl) | 1987-11-02 |
| JPS62267296A (ja) | 1987-11-19 |
| CA1322715C (en) | 1993-10-05 |
| IT1188646B (it) | 1988-01-20 |
| ATA88387A (de) | 1996-05-15 |
| ES2003043A6 (es) | 1988-10-01 |
| AU597048B2 (en) | 1990-05-24 |
| SE8701457D0 (sv) | 1987-04-07 |
| GB8708492D0 (en) | 1987-05-13 |
| GR870568B (en) | 1987-08-12 |
| IE59806B1 (en) | 1994-04-06 |
| BE1000263A4 (fr) | 1988-09-27 |
| AU7118287A (en) | 1987-10-15 |
| SE8701457L (sv) | 1987-10-10 |
| CH676467A5 (enrdf_load_stackoverflow) | 1991-01-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES2058796T3 (es) | Aislamiento y elucidacion estructural del depsipeptido citostatico lineal dolastatina 15. | |
| CA2029678A1 (en) | Isolation and structural elucidation of the cytostatic linear depsipeptide dolastatin 14 | |
| DK642587A (da) | Insulinpraeparat | |
| KR880000098A (ko) | 콘드로이틴 설페이트 면역자극 조성물 | |
| MXPA02007931A (es) | Analogos de nucleosido con base monociclica modificada con carboxamidina. | |
| ES2009216A6 (es) | Metodo de preparar un derivado de interleucina-lalfa. | |
| IL80149A (en) | Pharmaceutical compositions containing toluidide derivatives against graft-versus-host diseases and autoimmune diseases | |
| ES2179040T3 (es) | Utilizacion de 5-fluoro-2'-desoxi-3'-tiacitidina para el tratamiento de la hepatitis b. | |
| KR920702216A (ko) | 아세틸 d-카르니틴의 녹내장 치료에의 용도 | |
| AU7589587A (en) | Low dosage of interferon to enhance vaccine efficiency | |
| KR900007424A (ko) | 세포보호성 약제로서의 n-아세틸글루코사민의 사용방법 및 그 조성물 | |
| ES2062137T3 (es) | Utilizacion de 5'-deoxi-5'-metil-tioadenosina, s-adenosilmetionina y sus sales para la preparacion de composiciones farmaceuticas reductoras de seborrea. | |
| JPS52139713A (en) | Sustained release cefalexin preparations | |
| KR870010080A (ko) | 면역촉진 활성을 갖는 트리펩티드 | |
| AU2426592A (en) | New ganglioside derivatives | |
| GB8611946D0 (en) | Pharmaceutical preparations | |
| NO881778L (no) | Enkastiner: nye glykopeptider med enkefalinase-hemmende virkning. fremgangsmaate til deres fremstilling og deres anvendelse som farmasoeytiske preparater. | |
| KR870010079A (ko) | 면역촉진 활성을 갖는 트리펩티드 | |
| GB1483650A (en) | Pharmaceutical preparations based on mesterolone | |
| GB1351437A (en) | N-substituted amino acids having antiviral anti-inflammatory or anti-tumour activity | |
| GB1051686A (enrdf_load_stackoverflow) | ||
| MY114218A (en) | The use of bambuterol or a pharmaceutically acceptable salt thereof, to make lipid lowering pharmaceutical preparations. | |
| IT8748235A0 (it) | Peptidi e derivati peptidici, loro preparazione e loro impiego come medicamenti | |
| GB1363801A (en) | Peptides and their preparation | |
| ES2011230A4 (es) | Derivados peptidos del 3 - aminodihidrotiofeno - 2 - uno, procesos para la preparacion y uso terapeutico |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0109 | Patent application |
Patent event code: PA01091R01D Comment text: Patent Application Patent event date: 19870409 |
|
| PG1501 | Laying open of application | ||
| A201 | Request for examination | ||
| PA0201 | Request for examination |
Patent event code: PA02012R01D Patent event date: 19920313 Comment text: Request for Examination of Application Patent event code: PA02011R01I Patent event date: 19870409 Comment text: Patent Application |
|
| E902 | Notification of reason for refusal | ||
| PE0902 | Notice of grounds for rejection |
Comment text: Notification of reason for refusal Patent event date: 19950919 Patent event code: PE09021S01D |
|
| E601 | Decision to refuse application | ||
| PE0601 | Decision on rejection of patent |
Patent event date: 19960309 Comment text: Decision to Refuse Application Patent event code: PE06012S01D Patent event date: 19950919 Comment text: Notification of reason for refusal Patent event code: PE06011S01I |